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Article ; Online: Announcing a New Affiliated Society Member of Blood Purification: The Japan Association for Clinical Engineers.

Honma, Takashi

2018 Volume 46, Issue 2, Page(s) 143

Language	English
Publishing date	2018-04-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	605548-5
ISSN	1421-9735 ; 0253-5068
ISSN (online)	1421-9735
ISSN	0253-5068
DOI	10.1159/000489197
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Article: Announcing a New Affiliated Society Member of Blood Purification: The Japan Association for Clinical Engineers

Honma, Takashi

Blood Purification

2018 Volume 46, Issue 2, Page(s) 143–143

Language	English
Publishing date	2018-04-26
Publisher	S. Karger AG
Publishing place	Basel, Switzerland
Document type	Article
Note	Short Communication
ZDB-ID	605548-5
ISSN	1421-9735 ; 0253-5068
ISSN (online)	1421-9735
ISSN	0253-5068
DOI	10.1159/000489197
Database	Karger publisher's database

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Article ; Online: Primary pyomyositis in an infant following one-day afebrile upper limb monoplegia.

Takezawa, Yusuke / Niitsuma, Soh / Kawashima, Sayaka / Miyano, Shunsuke / Honma, Takashi

The journal of medical investigation : JMI

2021 Volume 68, Issue 3.4, Page(s) 372–375

Abstract: Background : Pyomyositis is a subacute bacterial infection of the skeletal muscles. Its most common features are fever, muscle swelling, and focal pain. There have been insufficient data regarding pyomyositis in healthy infants. Case report : A one-month- ...

Abstract	Background : Pyomyositis is a subacute bacterial infection of the skeletal muscles. Its most common features are fever, muscle swelling, and focal pain. There have been insufficient data regarding pyomyositis in healthy infants. Case report : A one-month-old boy presented with an impairment of his left arm movement. He was well-nourished and not under any apparent distress. His vital signs were within the normal limits but neurological examination revealed left forearm paralysis. Physical examination showed no abnormal findings in the region from the left shoulder joint to the fingertips. Considering these factors, an intracranial pathology was initially suspected. However, he developed a fever, regular tachycardia, and swelling in the left forearm. Magnetic resonance imaging revealed inflammation in the left forearm muscles. He was diagnosed with bacterial myositis and started on intravenous antibiotics. On the 17th day, he was discharged with oral antibiotic treatment, which was completed over 25 days without any sequelae nor relapse. Conclusion : Here we report the case of Japanese primary pyomyositis following one-day afebrile upper limb monoplegia in an infant. Even when infants exhibit afebrile symptoms, a bacterial infection should be suspected. J. Med. Invest. 68 : 372-375, August, 2021.
MeSH term(s)	Anti-Bacterial Agents/therapeutic use ; Forearm ; Hemiplegia/drug therapy ; Humans ; Infant ; Magnetic Resonance Imaging ; Male ; Pyomyositis/diagnosis ; Pyomyositis/drug therapy
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2021-11-10
Publishing country	Japan
Document type	Case Reports ; Journal Article
ZDB-ID	1435233-3
ISSN	1349-6867 ; 1343-1420
ISSN (online)	1349-6867
ISSN	1343-1420
DOI	10.2152/jmi.68.372
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Article ; Online: Walking aids and complicated orthopedic diseases are risk factors for falls in hemodialysis patients: an observational study.

Ishii, Takeo / Matsumoto, Wataru / Hoshino, Yui / Kagawa, Yasuhiro / Iwasaki, Emi / Takada, Hiromi / Honma, Takashi / Oyama, Kunio

BMC geriatrics

2023 Volume 23, Issue 1, Page(s) 319

Abstract: Background: Aging and an increased fall risk have been demonstrated in hemodialysis patients at home and in a facility. However, studies investigating the cause of falls to prevent fractures in dialysis rooms are scarce. This study aimed to explore the ... ...

Abstract	Background: Aging and an increased fall risk have been demonstrated in hemodialysis patients at home and in a facility. However, studies investigating the cause of falls to prevent fractures in dialysis rooms are scarce. This study aimed to explore the related factors for accidental falls statistically in dialysis facilities for future fall prevention. Methods: This study included 629 hemodialysis patients with end-stage renal disease. The patients were divided into two groups: the fall and non-fall groups. The main outcome was the presence or absence of falls in the dialysis room. Univariate and multivariate logistic analyses were performed; multivariate analysis was conducted using covariates significantly correlated in the univariate analysis. Results: A total of 133 patients experienced falling accidents during the study period. The multivariate analysis indicated that the use of walking aid (p < 0.001), orthopedic diseases (p < 0.05), cerebrovascular disease, and age were significantly correlated with falls. Conclusions: In the dialysis clinic, patients who use walking aids and have complicated orthopedic or cerebrovascular conditions are at a high risk of falling in the dialysis room. Therefore, establishing a safe environment may help prevent falls, not only for these patients but also among other patients with similar conditions.
MeSH term(s)	Humans ; Risk Factors ; Renal Dialysis/adverse effects ; Kidney Failure, Chronic/epidemiology ; Kidney Failure, Chronic/therapy ; Walking ; Ambulatory Care Facilities
Language	English
Publishing date	2023-05-22
Publishing country	England
Document type	Observational Study ; Journal Article
ZDB-ID	2059865-8
ISSN	1471-2318 ; 1471-2318
ISSN (online)	1471-2318
ISSN	1471-2318
DOI	10.1186/s12877-023-04015-9
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Book ; Conference proceedings: Casablanca - Chandigarh

Avermaete, Tom / Barrada, Yto / Casciato, Maristella / Honma, Takashi

a report on modernization ; [to accompany the exhibition "How architects, experts, politicians, international agencies, and citizens negotiate modern planning: Casablanca Chandigarh" presented at the CCA from 26 November 2013 to 20 April 2014]

2014

Institution	Canadian Centre for Architecture
Event/congress	Exhibition "How architects, experts, politicians, international agencies, and citizens negotiate modern planning: Casablanca Chandigarh (2013.11.29-2014.04.20, Montréal)
Author's details	Tom Avermaete; Maristella Casciato. Photogr. mission by Yto Barrada; Takahashi Homma
Language	English
Size	392 S., zahlr. Ill., Kt., 24 cm
Publisher	Park Books
Publishing place	Zürich
Document type	Book ; Conference proceedings
ISBN	9783906027364 ; 3906027368
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article ; Online: The effect of repetitive mild hyperthermia on body temperature, the autonomic nervous system, and innate and adaptive immunity.

Tomiyama, Chikako / Watanabe, Mayumi / Honma, Takashi / Inada, Akihiro / Hayakawa, Takayoshi / Ryufuku, Masae / Abo, Toru

Biomedical research (Tokyo, Japan)

2015 Volume 36, Issue 2, Page(s) 135–142

Abstract: The effect of repetitive mild hyperthermia on body temperature, the autonomic nervous system, and innate and adaptive immunity was investigated using a new hyperthermia treatment system, nanomist sauna (NMS). Six healthy volunteers participated and the ... ...

Abstract	The effect of repetitive mild hyperthermia on body temperature, the autonomic nervous system, and innate and adaptive immunity was investigated using a new hyperthermia treatment system, nanomist sauna (NMS). Six healthy volunteers participated and the concentration of catecholamines and cortisol, and the frequency and function of leukocytes in the peripheral blood were investigated before and after successive 7 days of hyperthermia treatment (20 min/day, 40°C, 100% relative humidity). After treatment, the blood level of adrenaline and cortisol on the 7th day was decreased compared with the 1st day, indicating the suppression of the sympathetic nervous system activity. Moreover, the frequency of CD56(+)NK, CD56(+)NKT and B cells on the 7th day tended to be increased compared with the 1st day. The frequency of HLA-DR-positive NK and NKT cells and expression of HLA-DR on B and T cells increased. The cytotoxicity of NK cells and proliferative response of B cells were also elevated. The results indicate that repetitive mild hyperthermia treatment might suppress excessive sympathetic dominance and modify immunity. Additionally, because it can provide the same effects as conventional hyperthermia treatments with minimal burden to the body, NMS may be a novel patient- and elderly-friendly hyperthermia treatment for health promotion.
MeSH term(s)	Adaptive Immunity ; Adult ; Autonomic Nervous System/metabolism ; B-Lymphocytes/metabolism ; Body Temperature ; Epinephrine/blood ; Histocompatibility Antigens Class II/metabolism ; Humans ; Hydrocortisone/blood ; Hyperthermia, Induced ; Immunity, Innate ; Male ; Middle Aged ; Natural Killer T-Cells/metabolism ; Norepinephrine/blood
Chemical Substances	Histocompatibility Antigens Class II ; Hydrocortisone (WI4X0X7BPJ) ; Norepinephrine (X4W3ENH1CV) ; Epinephrine (YKH834O4BH)
Language	English
Publishing date	2015
Publishing country	Japan
Document type	Journal Article
ZDB-ID	604561-3
ISSN	1880-313X ; 0388-6107
ISSN (online)	1880-313X
ISSN	0388-6107
DOI	10.2220/biomedres.36.135
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Zs.A 1654: Show issues

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Article: Somatodendritic localization of EFA6A, a guanine nucleotide exchange factor for ADP-ribosylation factor 6, and its possible interaction with alpha-actinin in dendritic spines.

Sakagami, Hiroyuki / Honma, Takashi / Sukegawa, Jun / Owada, Yuji / Yanagisawa, Teruyuki / Kondo, Hisatake

The European journal of neuroscience

2007 Volume 25, Issue 3, Page(s) 618–628

Abstract: EFA6A is a member of the guanine nucleotide exchange factors that can specifically activate ADP ribosylation factor 6 (ARF6). In this study, we identified alpha-actinin-1 as a possible interacting protein with EFA6A by the yeast two-hybrid screening with ...

Abstract	EFA6A is a member of the guanine nucleotide exchange factors that can specifically activate ADP ribosylation factor 6 (ARF6). In this study, we identified alpha-actinin-1 as a possible interacting protein with EFA6A by the yeast two-hybrid screening with its C-terminal region as bait. The central region of alpha-actinin-1 containing a part of spectrin repeat 1 and spectrin repeats 2-3 is responsible for this interaction. In the hippocampal formation, EFA6A immunoreactivity occurred at a high level as numerous fine puncta in the strata oriens, radiatum, lacunosum-moleculare of the hippocampal CA1-3 subfields and the dentate molecular layer, whereas the immunoreactivity was faint in the neuronal cell layers and the stratum lucidum, the mossy fiber-recipient layer of the CA3 subfield. Double-immunofluorescent analyses revealed a partial overlapping of EFA6A and alpha-actinin at the dendritic spines of in vivo and cultured hippocampal neurons. Our present findings suggest that EFA6A may form a protein complex with alpha-actinin and activate ARF6 in close proximity of the actin cytoskeleton and membrane proteins in the dendritic spines.
MeSH term(s)	ADP-Ribosylation Factors/metabolism ; Actinin/metabolism ; Animals ; Antibodies ; COS Cells ; Cells, Cultured ; Cercopithecus aethiops ; Dendritic Spines/metabolism ; Guanine/metabolism ; Guanine Nucleotide Exchange Factors/genetics ; Guanine Nucleotide Exchange Factors/immunology ; Guanine Nucleotide Exchange Factors/metabolism ; Hippocampus/cytology ; Hippocampus/physiology ; Immunohistochemistry ; Male ; Mice ; Mice, Inbred C57BL ; Neurons/physiology ; Neurons/ultrastructure ; Protein Binding/physiology ; Rabbits ; Two-Hybrid System Techniques ; Yeasts
Chemical Substances	Antibodies ; Guanine Nucleotide Exchange Factors ; Psd protein, mouse ; Actinin (11003-00-2) ; Guanine (5Z93L87A1R) ; ADP-Ribosylation Factors (EC 3.6.5.2) ; ADP-ribosylation factor 6 (EC 3.6.5.2)
Language	English
Publishing date	2007-02
Publishing country	France
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	645180-9
ISSN	1460-9568 ; 0953-816X
ISSN (online)	1460-9568
ISSN	0953-816X
DOI	10.1111/j.1460-9568.2007.05345.x
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Zs.A 2548: Show issues

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Article: Predominant localization of EFA6A, a guanine nucleotide exchange factor for ARF6, at the perisynaptic photoreceptor processes.

Katsumata, Osamu / Honma, Takashi / Sanda, Masashi / Kamata, Akifumi / Takeda, Shin'ichi / Kondo, Hisatake / Sakagami, Hiroyuki

Brain research

2008 Volume 1234, Page(s) 44–49

Abstract: EFA6A is a guanine nucleotide exchange factor that is highly expressed in the nervous system with the ability to activate ADP ribosylation factor 6 (ARF6). In this study, we demonstrated the immunohistochemical localization of EFA6A in the adult mouse ... ...

Abstract	EFA6A is a guanine nucleotide exchange factor that is highly expressed in the nervous system with the ability to activate ADP ribosylation factor 6 (ARF6). In this study, we demonstrated the immunohistochemical localization of EFA6A in the adult mouse retina. Strong immunoreactivity for EFA6A was detected predominantly in the outer plexiform layer (OPL), where EFA6A was partially overlapped with dystrophin and synaptophysin. Immunoelectron microscopic analysis revealed that EFA6A was localized predominantly at the perisynaptic processes of photoreceptor terminals without association with synaptic ribbons. These findings suggest that EFA6A-ARF6 pathway may play a specific role at a subcompartment of perisynaptic photoreceptor processes.
MeSH term(s)	ADP-Ribosylation Factors/metabolism ; Animals ; Dystrophin/metabolism ; Fluorescent Antibody Technique ; Guanine Nucleotide Exchange Factors/metabolism ; Guanine Nucleotides/metabolism ; Mice ; Mice, Inbred C57BL ; Microscopy, Immunoelectron ; Photoreceptor Cells, Vertebrate/metabolism ; Photoreceptor Cells, Vertebrate/ultrastructure ; Retina/metabolism ; Retina/ultrastructure ; Synapses/metabolism ; Synapses/ultrastructure ; Synaptophysin/metabolism
Chemical Substances	Dystrophin ; Guanine Nucleotide Exchange Factors ; Guanine Nucleotides ; Psd protein, mouse ; Synaptophysin ; ADP-Ribosylation Factors (EC 3.6.5.2) ; ADP-ribosylation factor 6 (EC 3.6.5.2)
Language	English
Publishing date	2008-10-09
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1200-2
ISSN	1872-6240 ; 0006-8993
ISSN (online)	1872-6240
ISSN	0006-8993
DOI	10.1016/j.brainres.2008.07.093
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Article: [A case of gastric mucosal bridge with Behçet's disease].

Nojima, Masanori / Abe, Takashi / Igarashi, Shinichi / Honma, Takashi / Oki, Mariko / Oikawa, Hiroto / Matsumoto, Shinichiro / Nishimura, Susumu / Matsunaga, Takahiro / Yawata, Atsushi / Kimura, Hirokazu / Takahashi, Hiroki / Imai, Kohzoh

Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology

2004 Volume 27, Issue 3, Page(s) 177–180

Abstract: A 69-year-old man visiting our hospital with an epigastralgia and tarry stool was diagnosed as having Behçet's disease on the basis of repetitious aphthous stomatitis, erythema nodosum and arthralgia in 1991. The next year, he suffered from double active ...

Abstract	A 69-year-old man visiting our hospital with an epigastralgia and tarry stool was diagnosed as having Behçet's disease on the basis of repetitious aphthous stomatitis, erythema nodosum and arthralgia in 1991. The next year, he suffered from double active ulcers in the antrum of the stomach, and he had been operated on for intestinal perforation. In 1994, endoscopic examination revealed the gastric mucosal bridge between the double ulcers. The double ulcer healed after an eradication therapy of H. pylori, but the gastric mucosal bridge has remained there on the gastrointestinal endoscopy. The gastric mucosal bridge with Behçet's disease has not been reported in Japan, being considered to be very rare.
MeSH term(s)	Aged ; Behcet Syndrome/complications ; Gastric Mucosa/pathology ; Gastroscopy ; Humans ; Intestinal Perforation/etiology ; Intestinal Perforation/surgery ; Male ; Pyloric Antrum/pathology ; Stomach Ulcer/complications ; Stomach Ulcer/pathology
Language	Japanese
Publishing date	2004-07-28
Publishing country	Japan
Document type	Case Reports ; English Abstract ; Journal Article
ZDB-ID	2019767-6
ISSN	1349-7413 ; 0911-4300
ISSN (online)	1349-7413
ISSN	0911-4300
DOI	10.2177/jsci.27.177
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Article: Performance of the newer type (Lixelle Type S-15) on direct hemoperfusion beta-2-microglobulin adsorption column for dialysis-related amyloidosis.

Hiyama, Emi / Hyodo, Toru / Kondo, Mitsuhiro / Otsuka, Kaori / Honma, Takashi / Taira, Takayasu / Yoshida, Kazunari / Uchida, Toyoaki / Endo, Tadao / Sakai, Tadasu / Baba, Siro / Hidai, Hideo

Nephron

2002 Volume 92, Issue 2, Page(s) 501–502

MeSH term(s)	Adsorption ; Amyloidosis/blood ; Amyloidosis/etiology ; Amyloidosis/therapy ; Hemoperfusion/instrumentation ; Hemoperfusion/methods ; Humans ; Renal Dialysis/adverse effects ; beta 2-Microglobulin/blood ; beta 2-Microglobulin/isolation & purification
Chemical Substances	beta 2-Microglobulin
Language	English
Publishing date	2002-10
Publishing country	Switzerland
Document type	Letter
ZDB-ID	207121-6
ISSN	1423-0186 ; 2235-3186 ; 1660-8151 ; 0028-2766
ISSN (online)	1423-0186 ; 2235-3186
ISSN	1660-8151 ; 0028-2766
DOI	10.1159/000063284
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