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  1. Article: Potential value of a rapid syndromic multiplex PCR for the diagnosis of native and prosthetic joint infections: a real-world evidence study.

    Pascual, Stéphanie / Noble, Brooklyn / Ahmad-Saeed, Nusreen / Aldridge, Catherine / Ambretti, Simone / Amit, Sharon / Annett, Rachel / O'Shea, Shaan Ashk / Barbui, Anna Maria / Barlow, Gavin / Barrett, Lucinda / Berth, Mario / Bondi, Alessandro / Boran, Nicola / Boyd, Sara E / Chaves, Catarina / Clauss, Martin / Davies, Peter / Dianzo-Delgado, Ileana T /
    Esteban, Jaime / Fuchs, Stefan / Friis-Hansen, Lennart / Goldenberger, Daniel / Golle, Andrej / Groonroos, Juha O / Hoffmann, Ines / Hoffmann, Tomer / Hughes, Harriet / Ivanova, Marina / Jezek, Peter / Jones, Gwennan / Ceren Karahan, Zeynep / Lass-Flörl, Cornelia / Laurent, Frédéric / Leach, Laura / Horsbøll Pedersen, Matilde Lee / Loiez, Caroline / Lynch, Maureen / Maloney, Robert J / Marsh, Martin / Milburn, Olivia / Mitchell, Shanine / Moore, Luke S P / Moffat, Lynn / Murdjeva, Marianna / Murphy, Michael E / Nayar, Deepa / Nigrisoli, Giacomo / O'Sullivan, Fionnuala / Öz, Büşra / Peach, Teresa / Petridou, Christina / Prinz, Mojgan / Rak, Mitja / Reidy, Niamh / Rossolini, Gian Maria / Roux, Anne-Laure / Ruiz-Garbajosa, Patricia / Saeed, Kordo / Salar-Vidal, Llanos / Salas Venero, Carlos / Selvaratnam, Mathyruban / Senneville, Eric / Starzengruber, Peter / Talbot, Ben / Taylor, Vanessa / Trebše, Rihard / Wearmouth, Deborah / Willinger, Birgit / Wouthuyzen-Bakker, Marjan / Couturier, Brianne / Allantaz, Florence

    Journal of bone and joint infection

    2024  Volume 9, Issue 1, Page(s) 87–97

    Abstract: ... ...

    Abstract Introduction
    Language English
    Publishing date 2024-02-28
    Publishing country Germany
    Document type Journal Article
    ISSN 2206-3552
    ISSN 2206-3552
    DOI 10.5194/jbji-9-87-2024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Potential value of a rapid syndromic multiplex PCR for the diagnosis of native and prosthetic joint infections

    Pascual, Stéphanie / Noble, Brooklyn / Ahmad-Saeed, Nusreen / Aldridge, Catherine / Ambretti, Simone / Amit, Sharon / Annett, Rachel / O'Shea, Shaan Ashk / Barbui, Anna Maria / Barlow, Gavin / Barrett, Lucinda / Berth, Mario / Bondi, Alessandro / Boran, Nicola / Boyd, Sara E. / Chaves, Catarina / Clauss, Martin / Davies, Peter / Dianzo-Delgado, Ileana T. /
    Esteban, Jaime / Fuchs, Stefan / Friis-Hansen, Lennart / Goldenberger, Daniel / Golle, Andrej / Groonroos, Juha O. / Hoffmann, Ines / Hoffmann, Tomer / Hughes, Harriet / Ivanova, Marina / Jezek, Peter / Jones, Gwennan / Ceren Karahan, Zeynep / Lass-Flörl, Cornelia / Laurent, Frédéric / Leach, Laura / Horsbøll Pedersen, Matilde Lee / Loiez, Caroline / Lynch, Maureen / Maloney, Robert J. / Marsh, Martin / Milburn, Olivia / Mitchell, Shanine / Moore, Luke S. P. / Moffat, Lynn / Murdjeva, Marianna / Murphy, Michael E. / Nayar, Deepa / Nigrisoli, Giacomo / O'Sullivan, Fionnuala / Öz, Büşra / Peach, Teresa / Petridou, Christina / Prinz, Mojgan / Rak, Mitja / Reidy, Niamh / Rossolini, Gian Maria / Roux, Anne-Laure / Ruiz-Garbajosa, Patricia / Saeed, Kordo / Salar-Vidal, Llanos / Salas Venero, Carlos / Selvaratnam, Mathyruban / Senneville, Eric / Starzengruber, Peter / Talbot, Ben / Taylor, Vanessa / Trebše, Rihard / Wearmouth, Deborah / Willinger, Birgit / Wouthuyzen-Bakker, Marjan / Couturier, Brianne / Allantaz, Florence

    eISSN: 2206-3552

    a real-world evidence study

    2024  

    Abstract: Introduction : The BIOFIRE Joint Infection (JI) Panel is a diagnostic tool that uses multiplex-PCR testing to detect microorganisms in synovial fluid specimens from patients suspected of having septic arthritis (SA) on native joints or prosthetic joint ... ...

    Abstract Introduction : The BIOFIRE Joint Infection (JI) Panel is a diagnostic tool that uses multiplex-PCR testing to detect microorganisms in synovial fluid specimens from patients suspected of having septic arthritis (SA) on native joints or prosthetic joint infections (PJIs). Methods : A study was conducted across 34 clinical sites in 19 European and Middle Eastern countries from March 2021 to June 2022 to assess the effectiveness of the BIOFIRE JI Panel. Results : A total of 1527 samples were collected from patients suspected of SA or PJI, with an overall agreement of 88.4 % and 85 % respectively between the JI Panel and synovial fluid cultures (SFCs). The JI Panel detected more positive samples and microorganisms than SFC, with a notable difference on Staphylococcus aureus , Streptococcus species, Enterococcus faecalis , Kingella kingae , Neisseria gonorrhoeae , and anaerobic bacteria. The study found that the BIOFIRE JI Panel has a high utility in the real-world clinical setting for suspected SA and PJI, providing diagnostic results in approximately 1 h. The user experience was positive, implying a potential benefit of rapidity of results' turnover in optimising patient management strategies. Conclusion : The study suggests that the BIOFIRE JI Panel could potentially optimise patient management and antimicrobial therapy, thus highlighting its importance in the clinical setting.
    Subject code 616
    Language English
    Publishing date 2024-02-28
    Publishing country de
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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