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  1. Article ; Online: Changes in Cognition and Brain Function After 26 Weeks of Progressive Resistance Training in Older Adults at Risk for Diabetes: A Pilot Randomized Controlled Trial.

    Furlano, Joyla A / Horst, Becky R / Petrella, Robert J / Shoemaker, J Kevin / Nagamatsu, Lindsay S

    Canadian journal of diabetes

    2023  Volume 47, Issue 3, Page(s) 250–256

    Abstract: Objectives: Type 2 diabetes is associated with deficits in cognition and brain health. Individuals with at least 1 risk factor for diabetes (i.e. obesity, prediabetes) already experience some neurocognitive impairment and are at risk for further decline. ...

    Abstract Objectives: Type 2 diabetes is associated with deficits in cognition and brain health. Individuals with at least 1 risk factor for diabetes (i.e. obesity, prediabetes) already experience some neurocognitive impairment and are at risk for further decline. One way to combat these deficits is through exercise, but it is unknown whether resistance exercise can improve these functions in this at-risk group.
    Methods: This study was a pilot randomized controlled trial. Participants were 60 to 80 years of age and had prediabetes (fasting capillary glucose 6.1 to 6.9 mmol/L) and/or were living with overweight or obesity (body mass index ≥25 kg/m
    Results: Resistance training led to improvements in task-switching, attention, and conflict resolution, as well as improved patterns of brain activation that may mimic healthy older adults.
    Conclusions: Resistance exercise may serve as an effective behavioural strategy to improve neurocognition in older adults at risk for type 2 diabetes. A large-scale powered trial is needed to further explore these findings.
    MeSH term(s) Humans ; Aged ; Resistance Training ; Diabetes Mellitus, Type 2 ; Prediabetic State/therapy ; Pilot Projects ; Cognition/physiology ; Exercise Therapy/methods ; Brain/diagnostic imaging ; Obesity
    Language English
    Publishing date 2023-01-13
    Publishing country Canada
    Document type Randomized Controlled Trial ; Journal Article
    ISSN 2352-3840
    ISSN (online) 2352-3840
    DOI 10.1016/j.jcjd.2023.01.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Brain deficits in prediabetic adults: A systematic review.

    Furlano, Joyla A / Horst, Becky R / Nagamatsu, Lindsay S

    Journal of neuroscience research

    2021  Volume 99, Issue 7, Page(s) 1725–1743

    Abstract: Previous findings on the relationship between prediabetes (the precursor stage of type 2 diabetes) and brain health in humans are inconsistent. Thus, this systematic review of cross-sectional and longitudinal studies aimed to summarize what is currently ... ...

    Abstract Previous findings on the relationship between prediabetes (the precursor stage of type 2 diabetes) and brain health in humans are inconsistent. Thus, this systematic review of cross-sectional and longitudinal studies aimed to summarize what is currently known about brain deficits in prediabetic adults. Following the PRISMA reporting standards for systematic reviews, we conducted a comprehensive review of peer-reviewed journal articles published from 2009 to present, focusing on studies that assessed brain volume, structural connectivity, and cerebrovascular health in prediabetic adults and older adults (i.e., 18 years or older). We systematically searched PsychINFO, Scopus, Web of Science, Ovid MEDLINE, CINAHL, and EMbase databases. Quality assessment was based on the NIH Quality Assessment Tool for Observational and Cross-sectional Studies. In total, 19 studies were included in our review. Results from these studies show that prediabetes may be associated with deficits in brain structure and pathology, however, several studies also refute these findings. Moreover, we identified clear inconsistencies in study methodologies, including diabetes measures and classification, across studies that may account for these conflicting findings.
    MeSH term(s) Brain/pathology ; Diabetes Mellitus, Type 2 ; Humans ; Prediabetic State/complications
    Language English
    Publishing date 2021-04-05
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 195324-2
    ISSN 1097-4547 ; 0360-4012
    ISSN (online) 1097-4547
    ISSN 0360-4012
    DOI 10.1002/jnr.24830
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Older People's Use of Digital Technology During the COVID-19 Pandemic.

    Sixsmith, Andrew / Horst, Becky R / Simeonov, Dorina / Mihailidis, Alex

    Bulletin of science, technology & society

    2022  Volume 42, Issue 1-2, Page(s) 19–24

    Abstract: Objectives: ...

    Abstract Objectives:
    Language English
    Publishing date 2022-09-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2008113-3
    ISSN 1552-4183 ; 0270-4676
    ISSN (online) 1552-4183
    ISSN 0270-4676
    DOI 10.1177/02704676221094731
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Demographic and Psychographic Factors of Social Isolation During the COVID-19 Pandemic: The Importance of Technology Confidence.

    Horst, Becky R / Sixsmith, Andrew / Simeonov, Dorina / Mihailidis, Alex

    Frontiers in public health

    2021  Volume 9, Page(s) 749515

    Abstract: The COVID-19 pandemic presents an unprecedented situation in which physical distancing and "stay at home" orders have increased the pressures for social isolation. Critically, certain demographic factors have been linked to increased feelings of ... ...

    Abstract The COVID-19 pandemic presents an unprecedented situation in which physical distancing and "stay at home" orders have increased the pressures for social isolation. Critically, certain demographic factors have been linked to increased feelings of isolation and loneliness. These at-risk groups for social isolation may be disproportionately affected by the changes and restrictions that have been implemented to prevent viral spread. In our analysis, we sought to evaluate if perceived feelings of social isolation, during the COVID-19 pandemic, was related to demographic and technology-related psychographic characteristics. Older adults across Canada were surveyed about their demographic background, their feelings concerning confidence and proficiency in technology use, and how frequently they have felt isolated during the pandemic. In total 927 responses from Canadians over 65 years old, of varying demographic characteristics were collected. Our data shows that many older adults are feeling isolated "Often" or "Some of the time" in 2020, regardless of most demographic factors that have been previously associated with increased isolation risk. However, feelings of proficiency in using technology was an important factor affecting feelings of isolation. Given that technology proficiency is a modifiable factor, and remained significant after adjustment for demographic factors, future efforts to reduce social isolation should consider training programs for older adults to improve technology confidence, especially in an increasingly digital world.
    MeSH term(s) Aged ; COVID-19 ; Canada/epidemiology ; Demography ; Humans ; Pandemics/prevention & control ; SARS-CoV-2 ; Social Isolation ; Technology
    Language English
    Publishing date 2021-10-28
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2021.749515
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Identification of Demographic Variables Influencing Dementia Literacy and Risk Perception Through a Global Survey.

    Horst, Becky R / Furlano, Joyla A / Wong, Michelle Y S / Ford, Sabrina D / Han, Brenna B / Nagamatsu, Lindsay S

    Frontiers in public health

    2021  Volume 9, Page(s) 660600

    Abstract: Dementia literacy is important for risk mitigation and preventative strategies before disease onset. The aim of our study was to investigate dementia literacy and how demographic characteristics influence these perceptions in order to provide evidence ... ...

    Abstract Dementia literacy is important for risk mitigation and preventative strategies before disease onset. The aim of our study was to investigate dementia literacy and how demographic characteristics influence these perceptions in order to provide evidence for how dementia-centered public health initiatives should structure their focus. We conducted a globally administered online survey, through Amazon Mechanical Turk (mTurk). Survey items evaluated: (1) personal perception on the preventability of dementia, and (2) risk awareness of lifestyle factors. Differences in risk scoring between the 598 respondents were compared using Kruskal-Wallis testing factored by demographic categorizations. Most of the sample demonstrated understanding that lifestyle factors contribute some risk toward dementia, though these risk scores were generally low. Differences in risk scoring varied by demographic characteristics. Women, older adults, those with non-post-secondary attainment, below average income, and White background tended to report lower risk scores. Public health education and initiatives for dementia prevention should focus on lifestyle risk factors, in addition to considering the barriers related to the demographic factors identified that may prevent populations from accessing programs and information.
    MeSH term(s) Aged ; Dementia/epidemiology ; Demography ; Female ; Humans ; Life Style ; Perception ; Surveys and Questionnaires
    Language English
    Publishing date 2021-06-08
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2021.660600
    Database MEDical Literature Analysis and Retrieval System OnLINE

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