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  1. Article: Can African-Americans Be Encouraged to Become Active Participants in Advanced Care Planning?

    Horton, Susan M

    Journal of National Black Nurses' Association : JNBNA

    2024  Volume 33, Issue 1, Page(s) 22–28

    Abstract: The purpose of this study was to encourage African-Americans to become active participants in advanced care planning through increased education and awareness. A quasi-experimental design was used in two local churches in Leon County. Thirty participants ...

    Abstract The purpose of this study was to encourage African-Americans to become active participants in advanced care planning through increased education and awareness. A quasi-experimental design was used in two local churches in Leon County. Thirty participants (N = 30) were African-Americans, 18 years of age and older, English speaking, from all socioeconomical levels, and from all educational backgrounds. The annotated 2003 Minnesota Survey was used to develop pre-survey and post-survey questions regarding advanced care planning. A paired t test was used to analyze the pre-survey and post-survey responses. The significant value was < 0.05, thus demonstrating a statistically significant difference in pre- and post-survey responses. The educational intervention on advanced directives indicated that all 30 participants would consider completing some form of advanced directive or discussing end-of-life care planning with either another person, a healthcare provider, or they would seek legal advice. African-Americans are more prone to chronic diseases. However, a systemic literature review describes how African-Americans were less likely to participate in advanced care planning and were less likely to receive end-of-life care than other ethnic groups. The 30-minute educational intervention encouraged African-Americans to participate in advanced care planning. Because the sample size was small, results cannot be generalized to all African-Americans. With increased educational opportunities, African-Americans may be encouraged to become active participants in advanced care planning. Advanced practice registered nurse providers should provide advanced care planning information to all patients, but especially to African-Americans. This study should be replicated in a wide variety of settings with larger numbers of participants. Further research is needed to discover additional methods of providing advanced care planning education to African-Americans.
    Language English
    Publishing date 2024-04-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1225465-4
    ISSN 0885-6028
    ISSN 0885-6028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4222: Show issues Location:
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  2. Book ; Online: Improving health and reducing poverty

    Jamison, Dean T. / Gelband, Hellen / Horton, Susan / Jha, Prabhat / Laxminarayan, Ramanan

    (Disease control priorities ; 9)

    2018  

    Author's details Editors: Dean T. Jamison, Hellen Gelband, Susan Horton, Prabhat Jha, Ramanan Laxminarayan [und zwei weitere]
    Series title Disease control priorities ; 9
    Collection
    Language English
    Size 1 Online Ressource (xix, 429 Seiten), Illustrationen, Diagramme
    Edition Third edition
    Publisher World Bank Group
    Publishing place Washington, DC
    Publishing country United States
    Document type Book ; Online
    HBZ-ID HT021875115
    ISBN 978-1-4648-0528-8 ; 9781464805271 ; 9781464805295 ; 1-4648-0528-8 ; 146480527X ; 1464805296
    DOI 10.1596/978-1-4648-0527-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Cancer

    Gelband, Hellen / Jha, Prabhat / Sankaranarayanan, Rengaswamy / Horton, Susan

    (Disease control priorities ; 3)

    2015  

    Author's details Editors: Hellen Gelband, Prabhat Jha, Rengaswamy Sankaranarayanan, Susan Horton
    Series title Disease control priorities ; 3
    Collection
    Keywords Neoplasms / prevention & control ; Neoplasms / economics ; Cost of Illness ; Health Services Research / economics ; Developing Countries
    Language English
    Size 1 Online Ressource (XVII, 341 Seiten), Illustrationen, Diagramme
    Publisher World Bank Group
    Publishing place Washington, DC
    Publishing country United States
    Document type Book ; Online
    HBZ-ID HT019018998
    ISBN 978-1-4648-0369-7 ; 9781464803505 ; 9781464803499 ; 1-4648-0369-2 ; 1464803501 ; 1464803498
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: A World Health Assembly resolution on diagnostics: what pathologists should know and do.

    Wilson, Michael L / Horton, Susan / Fleming, Kenneth A

    Histopathology

    2024  Volume 84, Issue 4, Page(s) 587–588

    MeSH term(s) Humans ; Pathologists ; Global Health
    Language English
    Publishing date 2024-02-05
    Publishing country England
    Document type Editorial
    ZDB-ID 131914-0
    ISSN 1365-2559 ; 0309-0167
    ISSN (online) 1365-2559
    ISSN 0309-0167
    DOI 10.1111/his.15049
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  5. Book ; Online: Child and adolescent health and development

    Bundy, Donald A. P. / Silva, Nilanthi de / Horton, Susan / Jamison, Dean T. / Patton, George C.

    (Disease control priorities ; 8)

    2018  

    Author's details Authors: Donald A.P. Bundy, Nilanthi de Silva, Susan Horton, Dean T. Jamison, George C. Patton
    Series title Disease control priorities ; 8
    Collection
    Language English
    Size 1 Online Ressource (xvii, 265 Seiten), Illustrationen, Diagramme, Karten
    Edition Third edition
    Publisher World Bank Group
    Publishing place Washington, DC
    Publishing country United States
    Document type Book ; Online
    HBZ-ID HT021875075
    ISBN 978-1-4648-0423-6 ; 978-1-4648-0439-7 ; 1-4648-0423-0 ; 1-4648-0439-7
    DOI 10.1596/978-1-4648-0423-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article ; Online: United States Department of Agriculture Facility Inspection for Exotic Veterinarians.

    Horton, Susan

    The veterinary clinics of North America. Exotic animal practice

    2018  Volume 21, Issue 3, Page(s) 669–684

    Abstract: This article reviews the necessary process an exotic veterinarian needs to understand when considering being an attending veterinarian for a United States Department of Agriculture regulated facility. ...

    Abstract This article reviews the necessary process an exotic veterinarian needs to understand when considering being an attending veterinarian for a United States Department of Agriculture regulated facility.
    MeSH term(s) Accreditation ; Animal Welfare ; Animals ; Animals, Exotic ; Humans ; Licensure ; United States ; United States Department of Agriculture ; Veterinary Medicine/standards
    Language English
    Publishing date 2018-08-06
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1558-4232
    ISSN (online) 1558-4232
    DOI 10.1016/j.cvex.2018.05.012
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  7. Article ; Online: Association between the use of Accredited Social Health Activist (ASHA) services and uptake of institutional deliveries in India.

    Mishra, Sujata / Horton, Susan / Bhutta, Zulfiqar A / Essue, Beverley M

    PLOS global public health

    2024  Volume 4, Issue 1, Page(s) e0002651

    Abstract: This study examines the impact of accredited social health activists (ASHAs), on increasing rates of institution-based deliveries among Indian women with a specific focus on the nine low-performing, empowered action group states and Assam (EAGA) in India. ...

    Abstract This study examines the impact of accredited social health activists (ASHAs), on increasing rates of institution-based deliveries among Indian women with a specific focus on the nine low-performing, empowered action group states and Assam (EAGA) in India. Using the latest round of the National Family Health Survey-V (2019-21), we first investigate the association between the use of ASHA services and socio-demographic attributes of women using a multivariate logistic regression. We then use propensity-score matching (PSM) to address observable selection bias in the data and assess the impact of ASHA services on the likelihood of institution-based deliveries using a generalized estimating equations model. Of the 232,920 women in our sample, 55.5% lived in EAGA states. Overall, 63.3% of women (70.6% in EAGA states) reported utilizing ASHA services, and 88.6% had an institution-based delivery (84.0% in EAGA states). Younger women from the poorest wealth index were more likely to use ASHA services and women in rural areas had a two-fold likelihood. Conversely, women with health insurance were less likely to use ASHA services compared to those without. Using PSM, the average treatment effect of using ASHA services on institution-based deliveries was 5.1% for all India (EAGA = 7.4%). The generalized estimating equations model indicated that the use of ASHA services significantly increased the likelihood of institution-based delivery by 1.6 times (95%CI = 1.5-1.7) for all India (EAGA = 1.8; 95%CI = 1.7-1.9). Our study finds that ASHAs are effective in enhancing the uptake of maternal services particularly institution-based deliveries. These findings underscore the necessity for continual, systematic investments to strengthen the ASHA program and to optimize the program's effectiveness in varied settings that rely on the community health worker model, thereby advancing child and maternal health outcomes.
    Language English
    Publishing date 2024-01-16
    Publishing country United States
    Document type Journal Article
    ISSN 2767-3375
    ISSN (online) 2767-3375
    DOI 10.1371/journal.pgph.0002651
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  8. Article ; Online: An Exploratory Analysis of the Cost-Effectiveness of a Multi-cancer Early Detection Blood Test Compared with Standard of Care Screening in Ontario, Canada.

    Lewis, Diedron / Wong, William W L / Lipscomb, Joseph / Horton, Susan

    PharmacoEconomics

    2023  Volume 42, Issue 4, Page(s) 393–407

    Abstract: Background: Determining whether multi-cancer early detection (MCED) tests are cost effective is important in deciding whether they should be included in the clinical path of cancer care, especially for cancers where screening tools do not exist.: ... ...

    Abstract Background: Determining whether multi-cancer early detection (MCED) tests are cost effective is important in deciding whether they should be included in the clinical path of cancer care, especially for cancers where screening tools do not exist.
    Research objective: The main objective of this study is to determine the cost effectiveness of including a MCED screening regimen together with existing provincial screening protocols for selected cancers that are prevalent in Ontario, Canada, among average risk persons aged 50-75 years. The selected cancers include breast, colorectal, lung, esophageal, liver, pancreatic, stomach, and ovarian.
    Methods: Cost effectiveness was estimated from a provincial Ministry of Health perspective. A state-transition Markov model representing the decision path of both the proposed and existing screening strategies along the natural history of the selected types of cancers was implemented. The incremental cost-effectiveness ratio (ICER) was calculated using data from available literature and the guidelines published by the Canadian Agency for Drugs and Technologies in Health (CADTH) for conducting a cost-effectiveness analysis, which included a discount rate of 1.5% applied to all costs and outcomes. Costs were also converted to 2022 Canadian dollars. To test the robustness of the model, both univariate and probabilistic sensitivity analyses were conducted.
    Results: MCED screening resulted in more diagnosed cases of each type of cancer, even at an earlier stage of disease. This was also associated with fewer related deaths compared with standard of care. Notwithstanding, the analysis revealed that the MCED intervention was not cost effective [ICER: CAD$143,369 per quality-adjusted life year (QALY)], given a willingness to pay (WTP) threshold of $100,000 per QALY. The probabilistic sensitivity analyses revealed that the MCED intervention strategy was preferred to standard of care no more than 2% of the time at this WTP for both males and females. The model was most sensitive to the cost of MCED screening, and the levels of specificity of the MCED and colorectal cancer screening tests.
    Conclusion: The main contribution of the study is to present and execute a methodological approach that can be adopted to test the cost effectiveness of an MCED tool in the Canadian setting. The model is also sufficiently generic that it could be adapted to other jurisdictions, and with consideration for increasing the WTP threshold beyond the common $100,000 per QALY limit, given the life-threatening nature of cancer, to ensure that MCED interventions are cost-effective.
    MeSH term(s) Female ; Male ; Humans ; Ontario ; Cost-Benefit Analysis ; Cost-Effectiveness Analysis ; Early Detection of Cancer ; Standard of Care ; Neoplasms ; Hematologic Tests ; Quality-Adjusted Life Years
    Language English
    Publishing date 2023-12-27
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 1100273-6
    ISSN 1179-2027 ; 1170-7690
    ISSN (online) 1179-2027
    ISSN 1170-7690
    DOI 10.1007/s40273-023-01345-9
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    Zs.A 3579: Show issues Location:
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  9. Article ; Online: Evaluating the impact of multicancer early detection testing on health and economic outcomes: Toward a decision modeling strategy.

    Lipscomb, Joseph / Horton, Susan / Kuo, Albert / Tomasetti, Cristian

    Cancer

    2022  Volume 128 Suppl 4, Page(s) 892–908

    Abstract: Emerging data provide initial support for the concept that a single, minimally invasive liquid biopsy test, performed in conjunction with confirmatory radiologic or other diagnostic testing, when indicated, could be deployed on a broad scale to screen ... ...

    Abstract Emerging data provide initial support for the concept that a single, minimally invasive liquid biopsy test, performed in conjunction with confirmatory radiologic or other diagnostic testing, when indicated, could be deployed on a broad scale to screen individuals for multiple types of cancer. Ideally, such a test could do this in a way that yields a clinically important percentage of true-positive indications of cancer while minimizing false-positive signals. Modern decision modeling approaches can and should be deployed to investigate the health and economic consequences of such multicancer early detection (MCED) testing within defined at-risk populations. In this paper, through small-scale analyses involving 3 hypothetical MCED-detectible cancers, the authors illustrate the potential for MCED testing to be cost-effective, along with the pivotal role of test-induced stage shift on results. The time is ripe for additional, prospective investigations of the clinical value of MCED testing, the benefits versus the risks for screened populations, and the overall projected impact on health outcomes and costs over time.
    MeSH term(s) Cost-Benefit Analysis ; Decision Support Techniques ; Early Detection of Cancer ; Humans ; Neoplasms/diagnosis ; Prospective Studies
    Language English
    Publishing date 2022-02-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1429-1
    ISSN 1097-0142 ; 0008-543X ; 1934-662X
    ISSN (online) 1097-0142
    ISSN 0008-543X ; 1934-662X
    DOI 10.1002/cncr.33980
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  10. Article ; Online: Expanding diagnostics for LMICs - Authors' reply.

    Fleming, Kenneth / Horton, Susan / Wilson, Michael L

    Lancet (London, England)

    2022  Volume 399, Issue 10335, Page(s) 1605–1606

    Language English
    Publishing date 2022-04-24
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(22)00230-6
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