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  1. Article: Bilateral anterior cerebral artery infarction following viper bite.

    Hoskote, S S / Iyer, Veena R / Kothari, V M / Sanghvi, Darshana A

    The Journal of the Association of Physicians of India

    2009  Volume 57, Page(s) 67–69

    Abstract: The viper is one of India's most commonly encountered poisonous snakes and envenomation following viper bite usually leads to consumption coagulopathy. Clinical manifestations most frequently include external and internal bleeding. In the setting of ... ...

    Abstract The viper is one of India's most commonly encountered poisonous snakes and envenomation following viper bite usually leads to consumption coagulopathy. Clinical manifestations most frequently include external and internal bleeding. In the setting of viper envenomation, large-vessel thrombosis is a very rare occurrence. Also, bilateral anterior cerebral artery infarction, when unrelated to anatomical abnormalities, subarachnoid haemorrhage, surgery or trauma, itself is an exceedingly rare event. We report a case of a 24-year-old previously healthy man who presented with bilateral anterior cerebral artery infarction following a viper bite. We also present hypotheses that may explain this unusual occurrence.
    MeSH term(s) Adult ; Amoxicillin/therapeutic use ; Animals ; Anti-Bacterial Agents/therapeutic use ; Antivenins/therapeutic use ; Cerebral Arteries/drug effects ; Cerebral Arteries/pathology ; Cerebral Infarction/chemically induced ; Cerebral Infarction/diagnosis ; Clavulanic Acid/therapeutic use ; Diuretics, Osmotic/therapeutic use ; Factor VIII ; Fibrinogen ; Humans ; Male ; Mannitol/therapeutic use ; Phenytoin/therapeutic use ; Plasma ; Snake Bites/complications ; Snake Bites/drug therapy ; Viper Venoms/poisoning ; Viperidae
    Chemical Substances Anti-Bacterial Agents ; Antivenins ; Diuretics, Osmotic ; Viper Venoms ; cryoprecipitate coagulum ; Clavulanic Acid (23521W1S24) ; Mannitol (3OWL53L36A) ; Phenytoin (6158TKW0C5) ; Amoxicillin (804826J2HU) ; Factor VIII (9001-27-8) ; Fibrinogen (9001-32-5)
    Language English
    Publishing date 2009-01
    Publishing country India
    Document type Case Reports ; Journal Article
    ZDB-ID 800766-4
    ISSN 0004-5772
    ISSN 0004-5772
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article: Prevalence of metabolic syndrome in an urban Indian diabetic population using the NCEP ATP III guidelines.

    Surana, S P / Shah, D B / Gala, K / Susheja, S / Hoskote, S S / Gill, Niharika / Joshi, S R / Panikar, Vijay

    The Journal of the Association of Physicians of India

    2008  Volume 56, Page(s) 865–868

    Abstract: Objective: To study the prevalence of metabolic syndrome (MetS) in an urban Indian diabetic population.: Research design and methods: A total of 5088 type 2 diabetes patients (2908 men and 2180 women) presenting to endocrinology clinics at four ... ...

    Abstract Objective: To study the prevalence of metabolic syndrome (MetS) in an urban Indian diabetic population.
    Research design and methods: A total of 5088 type 2 diabetes patients (2908 men and 2180 women) presenting to endocrinology clinics at four centers across Mumbai (a large metropolitan city in India) were selected for the study. Anthropometric (waist circumference), clinical (blood pressure) and biochemical (serum triglycerides, HDL, fasting and post-prandial blood glucose) data were recorded. Patients receiving treatment for hypertension or dyslipidemia were also included in the study and these were considered in the diagnosis of MetS even if the parameters were normal. The National Cholesterol Education Program Adult Treatment Panel III guidelines were used to diagnose MetS. The chi-square test was used to determine statistical significance, which was taken as a p value < 0.05.
    Results: The prevalence of MetS among urban Indian diabetic patients was 77.2% and was significantly higher in women (87.71%) as compared to men (69.33%) (p < 0.0001). The most prevalent risk factors for MetS were hypertension, followed by hypertriglyceridemia, in men, and central obesity, followed by hypertension, min women.
    Conclusions: MetS is highly prevalent in the urban Indian diabetic population. It should be identified by regular screening in individuals from the general population to avert or delay the progression to type 2 diabetes in order to reduce diabetes-related morbidity and mortality.
    MeSH term(s) Adult ; Aged ; Asian Continental Ancestry Group ; Blood Glucose/metabolism ; Cholesterol/blood ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/epidemiology ; Female ; Guidelines as Topic ; Humans ; Hypertension/epidemiology ; India/epidemiology ; Male ; Metabolic Syndrome/complications ; Metabolic Syndrome/epidemiology ; Middle Aged ; Obesity/epidemiology ; Prevalence ; Risk Factors ; Sex Distribution ; Triglycerides/blood ; Urban Population
    Chemical Substances Blood Glucose ; Triglycerides ; Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2008-11
    Publishing country India
    Document type Journal Article
    ZDB-ID 800766-4
    ISSN 0004-5772
    ISSN 0004-5772
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 313: Show issues Location:
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  3. Article: Efficacy, safety and acceptability of biphasic insulin aspart 30 in Indian patients with type 2 diabetes: results from the PRESENT study.

    Sharma, S K / Joshi, S R / Kumar, A / Unnikrishnan, A G / Hoskote, S S / Moharana, A K / Chakkarwar, P N / Vaz, J A

    The Journal of the Association of Physicians of India

    2008  Volume 56, Page(s) 859–863

    Abstract: Aim: The Physicians' Routine Evaluation of Safety and Efficacy of NovoMix 30 Therapy (PRESENT) study was done to assess the safety and effectiveness of biphasic insulin aspart 30 (BIAsp 30) in patients with type 2 diabetes mellitus in routine clinical ... ...

    Abstract Aim: The Physicians' Routine Evaluation of Safety and Efficacy of NovoMix 30 Therapy (PRESENT) study was done to assess the safety and effectiveness of biphasic insulin aspart 30 (BIAsp 30) in patients with type 2 diabetes mellitus in routine clinical practice.
    Materials and methods: This was a prospective, multicentric, multinational, observational study in type 2 diabetes patients. The patients were transferred to BIAsp 30 with or without oral antidiabetic drugs (OADs). We present the results of 6 months of treatment in the Indian cohort (n = 3559) with type 2 diabetes mellitus who were inadequately controlled on current treatment.
    Results: At three and six months, significant reductions from baseline were observed in the mean glycated haemoglobin (HbA1c) (-1.32% and -1.94%), fasting plasma glucose (-56.16 mg/dl and -75.24 mg/dl) and post-prandial plasma glucose (-88.74 mg/dl and -119.16 mg/dl) (p < 0.001). A significantly greater proportion of patients achieved target HbAlc of less than 7% at six months (31.1%), compared with baseline (3.1%), of which 70.4% did not report hypoglycaemia. The rate of total hypoglycaemia was reduced from 3.1 events per patient-year at baseline to 1.5 events per patient-year at end of the study. Episodes were mostly minor and diurnal. Except for two serious adverse drug reactions (ADRs) reported by one patient at 3 months, there were no reports of ADRs during the treatment period. More than 95% of patients and doctors were "very satisfied" or "satisfied" with BIAsp 30 treatment, compared to previous treatment.
    Conclusions: The use of BIAsp 30 monotherapy or in combination with OADs in clinical practice was effective and safe in poorly controlled Indian type 2 diabetes patients. Both patients and doctors showed a high degree of treatment satisfaction.
    MeSH term(s) Administration, Oral ; Biphasic Insulins ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Continental Population Groups ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/epidemiology ; Glycated Hemoglobin A/metabolism ; Humans ; Hypoglycemia/blood ; Hypoglycemia/chemically induced ; Hypoglycemia/drug therapy ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; India/epidemiology ; Injections, Subcutaneous ; Insulin/administration & dosage ; Insulin/analogs & derivatives ; Insulin/pharmacology ; Insulin/therapeutic use ; Insulin Aspart ; Insulin, Isophane ; Prospective Studies ; Treatment Outcome
    Chemical Substances Biphasic Insulins ; Blood Glucose ; Glycated Hemoglobin A ; Hypoglycemic Agents ; Insulin ; insulin aspart, insulin aspart protamine drug combination 30:70 ; Insulin, Isophane (53027-39-7) ; Insulin Aspart (D933668QVX)
    Language English
    Publishing date 2008-11
    Publishing country India
    Document type Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 800766-4
    ISSN 0004-5772
    ISSN 0004-5772
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 313: Show issues Location:
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