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  1. Article ; Online: Laryngopharyngeal Reflux: Effect of Race and Insurance Status on Symptomology.

    Varelas, Eleni A / Houser, Thomas K / Husain, Inna A

    The Annals of otology, rhinology, and laryngology

    2022  Volume 132, Issue 5, Page(s) 545–550

    Abstract: Objectives: Laryngopharyngeal reflux (LPR) is an extraesophageal variant of gastroesophageal reflux disease associated with intermittent dysphonia, throat-clearing, and chronic cough. This study aims to evaluate the impact of race and insurance status ... ...

    Abstract Objectives: Laryngopharyngeal reflux (LPR) is an extraesophageal variant of gastroesophageal reflux disease associated with intermittent dysphonia, throat-clearing, and chronic cough. This study aims to evaluate the impact of race and insurance status on symptoms often attributable to LPR.
    Methods: Retrospective review of all patients with suspected LPR from 2017 to 2019 was performed at a tertiary care center. The diagnostic criteria comprised evaluation by a fellowship trained laryngologist and Reflux Symptom Index (RSI) scores. Demographics, patient history, and insurance status were recorded. Descriptive statistics were calculated for each parameter using SPSS version 22.
    Results: A total of 170 patients (96 White, 44 Black, 26 Latinx, 4 Asian) were included in this study. About 57.1% had private insurance, 30.6% had Medicare, and 11.8% had Medicaid. Black and Latinx patients demonstrated higher RSI scores (26.67 ± 8.61,
    Conclusions: Black and Latinx patients presented with higher RSI scores than White and Asian patients. Similarly, Medicaid patients reported higher RSI scores than the Non-Medicaid cohort. These findings suggest that access to appropriate healthcare, due to varied insurance coverage and socioeconomic, may potentially influence symptoms attributed to LPR.
    MeSH term(s) Humans ; Aged ; United States/epidemiology ; Laryngopharyngeal Reflux/diagnosis ; Laryngopharyngeal Reflux/complications ; Medicare ; Retrospective Studies ; Dysphonia ; Insurance Coverage
    Language English
    Publishing date 2022-06-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 120642-4
    ISSN 1943-572X ; 0003-4894
    ISSN (online) 1943-572X
    ISSN 0003-4894
    DOI 10.1177/00034894221100025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Injection Laryngoplasty for Children with Dysphagia after Cardiac Surgery.

    Sheen, Derek / Houser, Thomas K / Olsson, Sofia E / Dabbous, Helene / Kou, Yann-Fuu / Johnson, Romaine F / Chorney, Stephen R

    OTO open

    2024  Volume 8, Issue 2, Page(s) e142

    Abstract: Objective: To determine whether injection laryngoplasty (IL) resolves thin liquid aspiration among children with unilateral vocal cord paralysis (UVCP) after cardiac surgery.: Study design: Retrospective case-control.: Setting: Tertiary children's ...

    Abstract Objective: To determine whether injection laryngoplasty (IL) resolves thin liquid aspiration among children with unilateral vocal cord paralysis (UVCP) after cardiac surgery.
    Study design: Retrospective case-control.
    Setting: Tertiary children's hospital.
    Methods: Consecutive children (<5 years) between 2012 and 2022 with UVCP after cardiac surgery were included. Resolution of thin liquid aspiration after IL versus observation was determined for children obtaining videofluoroscopic swallow studies (VFSS).
    Results: A total of 32 children with left UVCP after cardiac surgery met inclusion. Initial surgeries were N = 9 (28%) patent ductus arteriosus ligations, N = 7 (22%) aortic arch surgeries, N = 9 (28%) surgeries for hypoplastic left heart syndrome, and N = 7 (22%) other cardiac surgeries. The mean age at initial surgery was 1.8 months (SD: 3.7). All children had a VFSS obtained after surgery that confirmed aspiration. There were 17 children that obtained an IL at 33.6 months (SD: 20.9) after cardiac surgery and 15 children observed without IL procedure. No surgical complications after IL were noted. The rate of aspiration resolution based on postoperative VFSS was N = 14 (82%) for the IL group and N = 9 (60%) for the control group
    Conclusion: IL can help treat aspiration in children with UVCP after cardiac surgery but the benefit beyond observation remains unclear. Future studies should continue to explore the utility for IL in managing dysphagia in this pediatric population.
    Language English
    Publishing date 2024-04-30
    Publishing country United States
    Document type Journal Article
    ISSN 2473-974X
    ISSN (online) 2473-974X
    DOI 10.1002/oto2.142
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  3. Article ; Online: Effect of histopathological grade on treatment and survival in base of tongue adenocarcinoma.

    Houser, Thomas K / Patel, Tirth / Tajudeen, Bobby A / Bhayani, Mihir / Stenson, Kerstin / Al-Khudari, Samer

    American journal of otolaryngology

    2021  Volume 43, Issue 3, Page(s) 103265

    Abstract: Objectives: The purpose of this study was to investigate survival differences between low-grade and high-grade base of tongue (BOT) adenocarcinoma by examining demographics, tumor characteristics, and treatment modalities.: Methods: The National ... ...

    Abstract Objectives: The purpose of this study was to investigate survival differences between low-grade and high-grade base of tongue (BOT) adenocarcinoma by examining demographics, tumor characteristics, and treatment modalities.
    Methods: The National Cancer Database was queried for patients with BOT adenocarcinoma between 2004 and 2017. Univariate and multivariate analyses were performed for all cases of BOT adenocarcinoma. Subsequent analysis focused on low-grade (grade 1 and grade 2) and high-grade (grade 3 and grade 4) BOT adenocarcinoma.
    Results: A total of 286 patients with BOT adenocarcinoma were included in the main cohort and divided into low grade (n = 137) and high grade (n = 66). The 5-year overall survival for all patients, low-grade, and high-grade was 67%, 85%, and 58%, respectively. Prognostic factors associated with decreased survival for the main cohort include advanced age (hazard ratio [HR]: 1.04; 95% confidence interval [CI]: 1.02-1.06), non-white race (HR: 1.79; 95% CI: 1.04-3.25), public insurance (HR: 1.79; 95% CI: 1.02-3.14) and high-grade 3,4 (HR: 2.63; 95% CI: 1.51-4.56). The prognostic factor associated with increased survival for the main cohort was surgery (HR: 0.59; 95% CI: 0.36-0.96). Radiotherapy was associated with improved overall survival for high-grade BOT adenocarcinoma (HR: 0.09; 95% CI: 0.02-0.49) but not for low-grade BOT adenocarcinoma (HR: 0.93; 95% CI: 0.38-2.32).
    Conclusions: This investigation is the largest to date analyzing the association of treatment modalities with overall survival in BOT adenocarcinoma. Surgery remains standard of treatment, particularly in low-grade cases, with radiotherapy offering additional survival benefit for high-grade BOT adenocarcinoma.
    MeSH term(s) Adenocarcinoma/therapy ; Humans ; Proportional Hazards Models ; Retrospective Studies ; Tongue/pathology ; Tongue Neoplasms/pathology ; Tongue Neoplasms/therapy
    Language English
    Publishing date 2021-10-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2021.103265
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Improved sinonasal symptom and endoscopy sinus scores with dose-escalated intranasal mometasone irrigation in patients with refractory chronic rhinosinusitis.

    Papagiannopoulos, Peter / Brown, Hannah J / Kim, Young Jae / Houser, Thomas K / Ganti, Ashwin / Raad, Richard A / Kuan, Edward C / Losavio, Phillip / Batra, Pete S / Tajudeen, Bobby A

    International forum of allergy & rhinology

    2022  Volume 12, Issue 7, Page(s) 955–957

    MeSH term(s) Chronic Disease ; Endoscopy ; Humans ; Mometasone Furoate/therapeutic use ; Paranasal Sinuses/surgery ; Rhinitis/diagnosis ; Rhinitis/drug therapy ; Sinusitis/diagnosis ; Sinusitis/drug therapy ; Treatment Outcome
    Chemical Substances Mometasone Furoate (04201GDN4R)
    Language English
    Publishing date 2022-01-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2625826-2
    ISSN 2042-6984 ; 2042-6976
    ISSN (online) 2042-6984
    ISSN 2042-6976
    DOI 10.1002/alr.22940
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