LIVIVO - Suchergebnisse -

Suchergebnis

Treffer 1 - 10 von insgesamt 26

Suchoptionen

Artikel ; Online: Penciclovir pharmacokinetics after oral and rectal administration of famciclovir in African elephants (Loxodonta africana) shows that effective concentrations can be achieved from rectal administration, despite lower absorption.

Griffioen, John A / Fayette, Melissa A / Proudfoot, Jeffry S / Howard, Lauren L / Papich, Mark G

2024 , Seite(n) 1–9

Abstract: Objective: To evaluate the pharmacokinetics of famciclovir and its metabolite penciclovir following a single dose administered orally and rectally in African elephants (Loxodonta africana).: Animals: 15 African elephants (6 males and 9 females) of ... ...

Abstract	Objective: To evaluate the pharmacokinetics of famciclovir and its metabolite penciclovir following a single dose administered orally and rectally in African elephants (Loxodonta africana). Animals: 15 African elephants (6 males and 9 females) of various ages. Methods: Famciclovir (15 mg/kg) was administered orally or per rectum once, with at least a three-week washout period between administrations. Blood was collected at 13 different timepoints per administration for 6 elephants, occurring between February and March 2020. An additional 9 elephants were sampled at variable timepoints per administration utilizing a sparse sampling design between July 2020 and January 2021. Plasma famciclovir and penciclovir levels were measured via HPLC and fluorescence detection. Pharmacokinetic analysis was completed in the summer of 2021 using noncompartmental analysis and nonlinear mixed-effects modeling. Results: Famciclovir was not detected in any sample, suggesting complete metabolism. Key pharmacokinetic parameters for penciclovir following oral administration were time to maximum concentration (tmax; 2.12 hours), area under the concentration-versus-time curve (AUC; 33.93 μg·h/mL), maximum observed concentration (Cmax; 3.73 μg/mL), and absorption half-life (t1/2; 0.65 hours). Following rectal administration, the values were: tmax, 0.65 hours; AUC, 15.62 μg·h/mL; Cmax, 2.52 μg/mL; and absorption t1/2, 0.13 hours. Conclusions: Famciclovir was rapidly metabolized to penciclovir. Oral administration resulted in slower absorption but higher maximum plasma concentration and higher AUC compared to rectal administration. Clinical relevance: African elephants administered famciclovir via oral and rectal routes resulted in measurable serum penciclovir, and these findings may be utilized by clinicians treating viral infections in this species.
Sprache	Englisch
Erscheinungsdatum	2024-05-01
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	390796-x
ISSN	1943-5681 ; 0002-9645
ISSN (online)	1943-5681
ISSN	0002-9645
DOI	10.2460/ajvr.24.02.0039
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Verfügbar in ZB MED Köln/Königswinter

Zs.A 422: Hefte anzeigen

Standort:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Über subito bestellen

Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

Details ▾
- Im ZB MED-Bestand
- Kostenpflichtig bestellen

Artikel: Parturition and Neonatal Parameters of Three Species of Rhinoceros under Managed Care in the United States.

Brenner, Emily E / Howard, Lauren L / Capiro, Jonnie / Hernandez, Jorge A

Animals : an open access journal from MDPI

2023 Band 13, Heft 23

Abstract: Rhinoceros species range from near threatened to critically endangered due to habitat loss and poaching. A sustainable ex situ breeding population is critically important to maintain genetic diversity and help ensure the survival of the species; however, ...

Abstract	Rhinoceros species range from near threatened to critically endangered due to habitat loss and poaching. A sustainable ex situ breeding population is critically important to maintain genetic diversity and help ensure the survival of the species; however, not all populations under human care are self-sustaining. While rhinoceros reproductive physiology and pathology have been well studied, there is still a paucity of information describing the normal parameters of parturition and neonatal landmarks. Using video recordings, medical records, and keeper logs, we reviewed and compared data regarding the parturition of three rhinoceros species (black rhinoceros (BR) (
Sprache	Englisch
Erscheinungsdatum	2023-11-25
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani13233653
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Über subito bestellen

Details ▾
- Kostenpflichtig bestellen

Artikel: BIOLOGICAL VARIATION OF HEMATOLOGY PARAMETERS AND CLINICAL APPLICATION IN AFRICAN ELEPHANTS (

Browning, Geoffrey R / Kjelgaard-Hansen, Mads / Howard, Lauren L / Keener, Laura / LaFarga, Mindy / Perrin, Kathryn L

Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians

2024 Band 55, Heft 1, Seite(n) 173–181

Abstract: Detailed knowledge of biological variation can facilitate accurate interpretation of clinical pathology parameters. A recent biological variation study in Asian elephants ( ...

Abstract	Detailed knowledge of biological variation can facilitate accurate interpretation of clinical pathology parameters. A recent biological variation study in Asian elephants (
Mesh-Begriff(e)	Animals ; Elephants ; Hematology ; Herpesviridae ; Herpesviridae Infections/veterinary ; Retrospective Studies
Sprache	Englisch
Erscheinungsdatum	2024-03-06
Erscheinungsland	United States
Dokumenttyp	Case Reports ; Journal Article
ZDB-ID	2174930-9
ISSN	1937-2825 ; 1042-7260
ISSN (online)	1937-2825
ISSN	1042-7260
DOI	10.1638/2023-0055
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Über subito bestellen

Details ▾
- Kostenpflichtig bestellen

Artikel ; Online: Vesicular stomatitis virus in two species of rhinoceros at a California zoological park.

Berlin, Erin R / Kinney, Matthew E / Howard, Lauren L / Perrin, Kathryn L / Rodriguez, Paula / Kubiski, Steven V / Phair, Kristen A

American journal of veterinary research

2024 Band 85, Heft 5

Abstract: Objective: To describe an outbreak of vesicular stomatitis virus (VSV) in southern white rhinoceros (SWR; Ceratotherium simum simum) and greater one-horned rhinoceros (GOHR; Rhinoceros unicornis) at a safari park in San Diego, CA, from May to September ... ...

Abstract	Objective: To describe an outbreak of vesicular stomatitis virus (VSV) in southern white rhinoceros (SWR; Ceratotherium simum simum) and greater one-horned rhinoceros (GOHR; Rhinoceros unicornis) at a safari park in San Diego, CA, from May to September 2023. Animals: 21 SWR and 5 GOHR in professionally managed care. Methods: Rhinoceros of both species presented with a range of clinical signs and severities. Lesion locations were categorized as cutaneous (coronary bands, heels and soles, limbs, ventrum, neck folds, and ears) and mucocutaneous (lips, nostrils, mucous membranes of the oral cavity, and vulva). Clinical signs included lethargy, lameness, difficulty with prehension, hyporexia to anorexia, and hypersalivation. Severely affected rhinoceros had clinical pathology findings consistent with systemic inflammation. Results: Vesicular stomatitis New Jersey virus was confirmed via PCR from swabs of lesions in 10/26 (38%) rhinoceros. Of these 10 confirmed cases, 9 (90%) were SWR and 1 (10%) was a GOHR. A further 6/26 (24%) were considered probable cases, and 10/26 (38%) were considered suspect cases based on clinical signs, but the inability to appropriately sample due to the housing environment precluded confirmation. Histopathology samples from 3 rhinoceros were consistent with VSV, and viral RNA was localized in histologic lesions via RNA in situ hybridization for 1 case. All rhinoceros survived infection despite severe systemic illness in 2 animals. Clinical relevance: This case series describes the clinical appearance and progression of VSV in 2 rhinoceros species. To the authors' knowledge, this is the first report of VSV in a rhinoceros.
Mesh-Begriff(e)	Animals ; Perissodactyla/virology ; California/epidemiology ; Animals, Zoo ; Female ; Male ; Disease Outbreaks/veterinary ; Vesicular stomatitis New Jersey virus/genetics ; Vesicular stomatitis New Jersey virus/isolation & purification ; Vesicular Stomatitis/virology ; Vesicular Stomatitis/pathology
Sprache	Englisch
Erscheinungsdatum	2024-02-24
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	390796-x
ISSN	1943-5681 ; 0002-9645
ISSN (online)	1943-5681
ISSN	0002-9645
DOI	10.2460/ajvr.23.12.0284
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Verfügbar in ZB MED Köln/Königswinter

Zs.A 422: Hefte anzeigen

Standort:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Über subito bestellen

Details ▾
- Im ZB MED-Bestand
- Kostenpflichtig bestellen

Artikel: Comparison of diagnostic predictors of neonatal survivability in nondomestic caprinae

Bliss, Taylor N. / Marinkovich, Matt J. / Burns, Rachel E. / Carroll, Cody / Clancy, Meredith M. / Howard, Lauren L.

Journal of zoo and wildlife medicine. 2022 Mar. 11, v. 53, no. 1

2022

Abstract: This retrospective study evaluated whether six methods (glutamyltransferase, glutaraldehyde coagulation test, sodium sulfite precipitation test, total serum protein, glucose, and fibrinogen) used to assess passive transfer status in ruminants were ... ...

Abstract	This retrospective study evaluated whether six methods (glutamyltransferase, glutaraldehyde coagulation test, sodium sulfite precipitation test, total serum protein, glucose, and fibrinogen) used to assess passive transfer status in ruminants were predictive of survival of nondomestic Caprinae neonates in a zoological collection. A total of 184 neonates from 10 nondomestic Caprinae species had one or more testing methods performed within 7 d of birth. Results of each test were compared with the clinical condition (alive or dead) at 7, 30, and 90 d of age. Total protein (TP) results were not considered for statistical significance in this study. No statistical correlations between results of the serum gamma glutamyltransferase (GGT), glutaraldehyde coagulation test, or sodium sulfite precipitation test (BOVA-S) and survival at any age were found. A higher glucose level within 7 d of birth was associated with a greater probability of survival. Fibrinogen levels were found to have a strong negative association with survival at 30 and 90 d. Increased glucose concentration was negatively associated with the probability of an infectious cause of mortality and the need for medical intervention. In contrast, increased fibrinogen levels were associated with higher probabilities of infectious death and the need for major medical care. Neonates who were confirmed to have nursed had a lower likelihood of requiring major medical intervention. These findings suggest that glucose and fibrinogen levels are better predictors of neonatal survival in nondomestic Caprinae when compared to the other three tests reviewed in this study. Using survival as an indicator of adequate passive transfer in this group of neonates failed to identify a gold standard of diagnosis of failure of passive transfer, so more than one diagnostic test should be utilized.
Schlagwörter	blood serum ; coagulation ; death ; fibrinogen ; gamma-glutamyltransferase ; glucose ; glutaraldehyde ; medical treatment ; medicine ; mortality ; probability ; protein content ; retrospective studies ; sodium sulfite ; wildlife ; zoos
Sprache	Englisch
Erscheinungsverlauf	2022-0311
Umfang	p. 31-40.
Erscheinungsort	American Association of Zoo Veterinarians
Dokumenttyp	Artikel
ZDB-ID	2174930-9
ISSN	1937-2825 ; 1042-7260
ISSN (online)	1937-2825
ISSN	1042-7260
DOI	10.1638/2020-0064
Datenquelle	NAL Katalog (AGRICOLA)

Zusatzmaterialien

Über subito bestellen

Details ▾
- Kostenpflichtig bestellen

Artikel: COMPARISON OF DIAGNOSTIC PREDICTORS OF NEONATAL SURVIVABILITY IN NONDOMESTIC CAPRINAE.

Bliss, Taylor N / Marinkovich, Matt J / Burns, Rachel E / Carroll, Cody / Clancy, Meredith M / Howard, Lauren L

Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians

2022 Band 53, Heft 1, Seite(n) 31–40

Abstract	This retrospective study evaluated whether six methods (glutamyltransferase, glutaraldehyde coagulation test, sodium sulfite precipitation test, total serum protein, glucose, and fibrinogen) used to assess passive transfer status in ruminants were predictive of survival of nondomestic Caprinae neonates in a zoological collection. A total of 184 neonates from 10 nondomestic Caprinae species had one or more testing methods performed within 7 d of birth. Results of each test were compared with the clinical condition (alive or dead) at 7, 30, and 90 d of age. Total protein (TP) results were not considered for statistical significance in this study. No statistical correlations between results of the serum gamma glutamyltransferase (GGT), glutaraldehyde coagulation test, or sodium sulfite precipitation test (BOVA-S) and survival at any age were found. A higher glucose level within 7 d of birth was associated with a greater probability of survival. Fibrinogen levels were found to have a strong negative association with survival at 30 and 90 d. Increased glucose concentration was negatively associated with the probability of an infectious cause of mortality and the need for medical intervention. In contrast, increased fibrinogen levels were associated with higher probabilities of infectious death and the need for major medical care. Neonates who were confirmed to have nursed had a lower likelihood of requiring major medical intervention. These findings suggest that glucose and fibrinogen levels are better predictors of neonatal survival in nondomestic Caprinae when compared to the other three tests reviewed in this study. Using survival as an indicator of adequate passive transfer in this group of neonates failed to identify a gold standard of diagnosis of failure of passive transfer, so more than one diagnostic test should be utilized.
Mesh-Begriff(e)	Animals ; Animals, Newborn ; Glutaral ; Retrospective Studies ; Ruminants ; gamma-Glutamyltransferase
Chemische Substanzen	gamma-Glutamyltransferase (EC 2.3.2.2) ; Glutaral (T3C89M417N)
Sprache	Englisch
Erscheinungsdatum	2022-03-23
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	2174930-9
ISSN	1937-2825 ; 1042-7260
ISSN (online)	1937-2825
ISSN	1042-7260
DOI	10.1638/2020-0064
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Über subito bestellen

Details ▾
- Kostenpflichtig bestellen

Artikel ; Online: Pharmacokinetics of intravenous propofol in southern white rhinoceros (Ceratotherium simum simum) after intramuscular etorphine-butorphanol-medetomidine-azaperone.

Berlin, Erin R / Kinney, Matthew E / Howard, Lauren L / Perrin, Kathryn L / Phair, Kristen A / Clancy, Meredith M / Ferris, Rachel L / Knych, Heather K / Mama, Khursheed R

American journal of veterinary research

2023 Band 84, Heft 4

Abstract: Objective: To determine the pharmacokinetics of a single bolus of intravenous (IV) propofol after intramuscular administration of etorphine, butorphanol, medetomidine, and azaperone in 5 southern white rhinoceros to facilitate reproductive evaluations. ... ...

Abstract	Objective: To determine the pharmacokinetics of a single bolus of intravenous (IV) propofol after intramuscular administration of etorphine, butorphanol, medetomidine, and azaperone in 5 southern white rhinoceros to facilitate reproductive evaluations. A specific consideration was whether propofol would facilitate timely orotracheal intubation. Animals: 5 adult, female, zoo-maintained southern white rhinoceros. Procedures: Rhinoceros were administered etorphine (0.002 mg/kg), butorphanol (0.02 to 0.026 mg/kg), medetomidine (0.023 to 0.025 mg/kg), and azaperone (0.014 to 0.017 mg/kg) intramuscularly (IM) prior to an IV dose of propofol (0.5 mg/kg). Physiologic parameters (heart rate, blood pressure, respiratory rate, and capnography), timed parameters (eg, time to initial effects and intubation), and quality of induction and intubation were recorded following drug administration. Venous blood was collected for analysis of plasma propofol concentrations using liquid chromatography-tandem mass spectrometry at various time points after propofol administration. Results: All animals were approachable following IM drug administration, and orotracheal intubation was achieved at 9.8 ± 2.0 minutes (mean ±SD) following propofol administration. The mean clearance for propofol was 14.2 ± 7.7 ml/min/kg, the mean terminal half-life was 82.4 ± 74.4 minutes, and the maximum concentration occurred at 2.8 ± 2.9 minutes. Two of 5 rhinoceros experienced apnea after propofol administration. Initial hypertension, which improved without intervention, was observed. Clinical relevance: This study provides pharmacokinetic data and insight into the effects of propofol in rhinoceros anesthetized using etorphine, butorphanol, medetomidine, and azaperone. While apnea was observed in 2 rhinoceros, propofol administration allowed for rapid control of the airway and facilitated oxygen administration and ventilatory support.
Mesh-Begriff(e)	Female ; Animals ; Etorphine/pharmacology ; Butorphanol ; Azaperone/pharmacology ; Propofol ; Medetomidine/pharmacology ; Hypnotics and Sedatives/pharmacology ; Apnea/drug therapy ; Apnea/veterinary ; Perissodactyla/physiology
Chemische Substanzen	Etorphine (42M2Y6NU9O) ; Butorphanol (QV897JC36D) ; Azaperone (19BV78AK7W) ; Propofol (YI7VU623SF) ; Medetomidine (MR15E85MQM) ; Hypnotics and Sedatives
Sprache	Englisch
Erscheinungsdatum	2023-02-27
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	390796-x
ISSN	1943-5681 ; 0002-9645
ISSN (online)	1943-5681
ISSN	0002-9645
DOI	10.2460/ajvr.22.12.0224
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Verfügbar in ZB MED Köln/Königswinter

Zs.A 422: Hefte anzeigen

Standort:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Über subito bestellen

Details ▾
- Im ZB MED-Bestand
- Kostenpflichtig bestellen

Artikel: Noninvasive sampling for detection of elephant endotheliotropic herpesvirus and genomic dna in asian (elephas maximus) and african (loxodonta africana) elephants

Jeffrey, Alison / Evans, Tierra Smiley / Molter, Christine / Howard, Lauren L / Ling, Paul / Goldstein, Tracey / Gilardi, Kirsten

Journal of zoo and wildlife medicine. 2020 June 12, v. 51, no. 2

2020

Abstract: Elephant endotheliotropic herpesvirus (EEHV) hemorrhagic disease (EEHV-HD) threatens Asian elephant (Elephas maximus) population sustainability in North America. Clusters of cases have also been reported in African elephants (Loxodonta africana). Risk to ...

Abstract	Elephant endotheliotropic herpesvirus (EEHV) hemorrhagic disease (EEHV-HD) threatens Asian elephant (Elephas maximus) population sustainability in North America. Clusters of cases have also been reported in African elephants (Loxodonta africana). Risk to range country elephant populations is unknown. Currently, EEHV detection depends upon sampling elephants trained for invasive blood and trunk wash collection. To evaluate noninvasive sample collection options, paired invasively collected (blood, trunk wash and oral swabs), and noninvasively collected (chewed plant and fecal) samples were compared over 6 wk from 9 Asian elephants and 12 African elephants. EEHV shedding was detected simultaneously in a paired trunk wash and fecal sample from one African elephant. Elephant γ herpesvirus-1 shedding was identified in six chewed plant samples collected from four Asian elephants. Noninvasively collected samples can be used to detect elephant herpesvirus shedding. Longer sampling periods are needed to evaluate the clinical usefulness of noninvasive sampling for EEHV detection.
Schlagwörter	DNA ; Elephantid betaherpesvirus 1 ; Elephas maximus ; Loxodonta africana ; blood ; feces ; medicine ; risk ; wildlife ; zoos ; North America
Sprache	Englisch
Erscheinungsverlauf	2020-0612
Umfang	p. 433-437.
Erscheinungsort	American Association of Zoo Veterinarians
Dokumenttyp	Artikel
Anmerkung	NAL-AP-2-clean
ZDB-ID	2174930-9
ISSN	1937-2825 ; 1042-7260
ISSN (online)	1937-2825
ISSN	1042-7260
DOI	10.1638/2019-0112
Datenquelle	NAL Katalog (AGRICOLA)

Zusatzmaterialien

Über subito bestellen

Details ▾
- Kostenpflichtig bestellen

Artikel: A comparison of a single-dart versus staged two-dart anesthesia induction protocol in przewalski's horses (equus ferus przewalskii)

Ellis, Jayne S / Mama, Khursheed R / Rao, Sangeeta / Sadler, Ryan A / Marinkovich, Matt / Clancy, Meredith M / Howard, Lauren L / Lamberski, Nadine / Kinney, Matthew E

Journal of zoo and wildlife medicine. 2021 June 11, v. 52, no. 2

2021

Abstract: Przewalski's horses (Equus ferus przewalskii) are an endangered equid species. Anesthesia administered by remote delivery is often needed to provide medical care. Behavioral and physiologic parameters were prospectively compared in 14 horses (8 females ... ...

Abstract	Przewalski's horses (Equus ferus przewalskii) are an endangered equid species. Anesthesia administered by remote delivery is often needed to provide medical care. Behavioral and physiologic parameters were prospectively compared in 14 horses (8 females and 6 males, 3–18 yr) after a single-dart or staged two-dart anesthesia induction protocol with intramuscular medetomidine (0.06 mg/kg), butorphanol (0.05 mg/kg), thiafentanil (0.02 mg/kg), and ketamine (1 mg/kg). Seven horses were randomly assigned to receive all drugs in a single dart, and the other seven to receive medetomidine and butorphanol 10 min prior to thiafentanil and ketamine in a second dart. Induction and recovery quality were scored on a scale from 1 to 5 (worst to best), and video recordings were assessed for frequency of specific behaviors. Need for supplemental propofol was recorded. Median induction score was significantly better (P = 0.01) after two darts (4/5) compared to a single dart (3/5). Degree of muscle fasciculation (undesirable) during induction was significantly lower (P= 0.006) with the two-dart protocol. During the transition to recumbency, 71% versus 14% of horses transitioned headfirst (undesirable) after a single dart versus two darts, respectively (P= 0.07). Supplemental propofol administration was necessary in 43% of horses after two darts and in 100% of horses after a single dart (P= 0.10) to facilitate intubation and reach a working depth of anesthesia. Physiologic and recovery parameters were not significantly different between groups. Improved induction quality was observed clinically using a staged two-dart versus a single-dart protocol and should be considered when anesthetizing captive Przewalski's horses using this drug combination.
Schlagwörter	Equus przewalskii ; butorphanol ; depth of anesthesia ; ketamine ; medetomidine ; medicine ; muscles ; wildlife ; zoos
Sprache	Englisch
Erscheinungsverlauf	2021-0611
Umfang	p. 453-459.
Erscheinungsort	American Association of Zoo Veterinarians
Dokumenttyp	Artikel
Anmerkung	NAL-AP-2-clean
ZDB-ID	2174930-9
ISSN	1937-2825 ; 1042-7260
ISSN (online)	1937-2825
ISSN	1042-7260
DOI	10.1638/2020-0133
Datenquelle	NAL Katalog (AGRICOLA)

Zusatzmaterialien

Über subito bestellen

Details ▾
- Kostenpflichtig bestellen

Artikel ; Online: Chlamydia pneumoniae Polioencephalomyelitis and Ganglionitis in Captive Houston Toads (Anaxyrus houstonensis)

Fratzke, Alycia / Howard, Lauren L. / Tocidlowski, Maryanne E. / Armién, Anibal / Oliveira, Fabiano / Ritchie, Branson / Berlin, Erin / Snook, Eric

Veterinary Pathology. 2019 Sept., v. 56, no. 5 p.789-793

2019

Abstract: Chlamydia pneumoniae is a ubiquitous pathogen causing disease in humans, mammals, birds, reptiles, and amphibians. Since 2012, C. pneumoniae infection has caused neurologic disease and mortality in a breeding colony of endangered Houston toads (Anaxyrus ... ...

Abstract	Chlamydia pneumoniae is a ubiquitous pathogen causing disease in humans, mammals, birds, reptiles, and amphibians. Since 2012, C. pneumoniae infection has caused neurologic disease and mortality in a breeding colony of endangered Houston toads (Anaxyrus houstonensis) at the Houston Zoo. The purpose of this report is to present the histopathologic and ultrastructural characteristics of C. pneumoniae infection in Houston toads. Fourteen cases were evaluated by histopathology and 1 case was evaluated by electron microscopy. The major histopathologic finding was necrotizing and histiocytic polioencephalomyelitis and ganglionitis. Bacteria formed intracytoplasmic inclusions within neurons but frequently extended into the surrounding tissue from necrotic cells. Ultrastructural evaluation showed the bacteria formed reticulate and elementary bodies characteristic of Chlamydia spp.
Schlagwörter	Anaxyrus ; Chlamydia ; Chlamydophila pneumoniae ; animal pathology ; electron microscopy ; histopathology ; mortality ; pathogens ; zoos ; brain ; Chlamydia pneumoniae ; encephalomyelitis ; ganglionitis ; Houston toads ; spinal cord ; endangered species
Sprache	Englisch
Erscheinungsverlauf	2019-09
Umfang	p. 789-793.
Erscheinungsort	SAGE Publications
Dokumenttyp	Artikel ; Online
ZDB-ID	188012-3
ISSN	1544-2217 ; 0300-9858
ISSN (online)	1544-2217
ISSN	0300-9858
DOI	10.1177/0300985819844818
Datenquelle	NAL Katalog (AGRICOLA)

Zusatzmaterialien

Verfügbar in ZB MED Bonn

Z 1959: Hefte anzeigen

Über subito bestellen

Fernleihe an ZB MED

Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Details ▾
- Im ZB MED-Bestand
- Kostenpflichtig bestellen

Zum Seitenanfang

Ihre letzten Suchen

Zusatzmaterialien

Kategorien

Verfügbar in ZB MED Köln/Königswinter

Über subito bestellen

Zusatzmaterialien

Kategorien

Über subito bestellen

Zusatzmaterialien

Kategorien

Über subito bestellen

Zusatzmaterialien

Kategorien

Verfügbar in ZB MED Köln/Königswinter

Über subito bestellen

Zusatzmaterialien

Kategorien

Über subito bestellen

Zusatzmaterialien

Kategorien

Über subito bestellen

Zusatzmaterialien

Kategorien

Verfügbar in ZB MED Köln/Königswinter

Über subito bestellen

Zusatzmaterialien

Kategorien

Über subito bestellen

Zusatzmaterialien

Kategorien

Über subito bestellen

Zusatzmaterialien

Kategorien

Verfügbar in ZB MED Bonn

Über subito bestellen

Fernleihe an ZB MED