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  1. Article ; Online: Staged Revision Hip Arthroplasty With Femoral Impaction Bone Grafting for Prosthetic Joint Infections: Radiostereometric Analyses and Clinical Outcomes at Minimum 5-Year Follow-Up.

    Bunting, Alexandra C / Costi, Kerry / Chimutengwende-Gordon, Mukai / Callary, Stuart A / Pannach, Susan / Nelson, Renjy / Howie, Donald W / Solomon, Lucian Bogdan

    The Journal of arthroplasty

    2023  Volume 38, Issue 12, Page(s) 2716–2723.e1

    Abstract: Background: There are ongoing concerns regarding the use of bone graft following prosthetic joint infection and subsequent implant subsidence. The aim of this study was to determine whether the use of a cemented stem combined with femoral impaction bone ...

    Abstract Background: There are ongoing concerns regarding the use of bone graft following prosthetic joint infection and subsequent implant subsidence. The aim of this study was to determine whether the use of a cemented stem combined with femoral impaction bone grafting (FIBG) at second stage revision for infection results in stable femoral stem fixation, determined by accurate methods, and good clinical results.
    Methods: A prospective cohort of 29 patients underwent staged revision total hip arthroplasty for infection using an interval prosthesis followed by FIBG at the final reconstruction. The mean follow-up was 89 months (range, 8 to 167 months). Femoral implant subsidence was measured with radiostereometric analysis. Clinical outcomes included the Harris Hip Score, Harris Pain score and Société Internationale de Chirurgie Orthopédique et de Traumatologie activity scores.
    Results: At 2-years follow-up the median stem subsidence relative to femur was -1.36 mm (range, -0.31 to -4.98), while the cement subsidence relative to femur was -0.05 mm (range, 0.36 to -0.73). At 5-years follow-up, the median stem subsidence relative to femur was -1.89 mm (range, -0.27 to -6.35), while the cement subsidence relative to femur was -0.06 mm (range, 0.44 to -0.55). There were 25 patients who were confirmed infection-free after the second stage revision with FIBG. The median Harris Hip Score improved from 51 pre-operatively to 79 at 5 years (P = .0130), and Harris Pain score from 20 to 40 (P = .0038).
    Conclusions: Stable femoral component fixation can be achieved with FIBG when reconstructing the femur after revision for infection without compromising infection cure rates and patient-reported outcomes.
    MeSH term(s) Humans ; Arthroplasty, Replacement, Hip/adverse effects ; Arthroplasty, Replacement, Hip/methods ; Radiostereometric Analysis ; Hip Prosthesis/adverse effects ; Follow-Up Studies ; Bone Transplantation/methods ; Prospective Studies ; Prosthesis Design ; Femur/surgery ; Reoperation/methods ; Bone Cements ; Pain/surgery ; Prosthesis Failure
    Chemical Substances Bone Cements
    Language English
    Publishing date 2023-06-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 632770-9
    ISSN 1532-8406 ; 0883-5403
    ISSN (online) 1532-8406
    ISSN 0883-5403
    DOI 10.1016/j.arth.2023.06.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Highly Porous Tantalum Acetabular Components Without Ancillary Screws Have Similar Migration to Porous Titanium Acetabular Components With Screws at 2 Years: A Randomized Controlled Trial.

    Howie, Donald W / Holubowycz, Oksana T / Callary, Stuart A / Robertson, Thomas S / Solomon, Lucian B

    The Journal of arthroplasty

    2020  Volume 35, Issue 10, Page(s) 2931–2937

    Abstract: Background: It is proposed that highly porous coatings on acetabular components, such as a porous tantalum coating, provide adequate fixation without ancillary screw fixation in primary total hip arthroplasty (THA). However, tantalum acetabular ... ...

    Abstract Background: It is proposed that highly porous coatings on acetabular components, such as a porous tantalum coating, provide adequate fixation without ancillary screw fixation in primary total hip arthroplasty (THA). However, tantalum acetabular components have been associated with higher rates of revision than other uncemented components in national registries. The aim of this randomized controlled trial is to determine whether the early migration of a solid-backed tantalum acetabular component was no greater than that of a titanium acetabular component with ancillary screw fixation that has proven good clinical results.
    Methods: Sixty-six patients aged 40 to 64 years, with osteoarthritis and Charnley grade A or B activity grade and who underwent primary THA, were recruited into the trial. Patients were randomized intraoperatively to receive either the tantalum or titanium acetabular component. All patients received the same cemented polished tapered femoral stem, 28-mm cobalt-chromium femoral head, and highly cross-linked polyethylene liner. Acetabular component migration was measured using radiostereometric analysis at 4-6 days postoperatively and at 6 weeks, 3 months, 1 and 2 years following THA.
    Results: The mean proximal migration at 2 years for the tantalum cohort was 0.17 mm (95% confidence interval, 0.09-0.24) which was no greater than that of the titanium cohort which was 0.19 mm (0.07-0.32). Harris hip scores and functional activity scores were similar between groups.
    Conclusion: These results demonstrate that early stability can be achieved without ancillary screw fixation through the use of a highly porous high friction coating on a solid-backed modular acetabular component.
    Level of evidence: Level I.
    MeSH term(s) Acetabulum/surgery ; Adult ; Arthroplasty, Replacement, Hip ; Bone Screws ; Follow-Up Studies ; Hip Prosthesis ; Humans ; Middle Aged ; Porosity ; Prosthesis Design ; Prosthesis Failure ; Reoperation ; Tantalum ; Titanium
    Chemical Substances Tantalum (6424HBN274) ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2020-05-28
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 632770-9
    ISSN 1532-8406 ; 0883-5403
    ISSN (online) 1532-8406
    ISSN 0883-5403
    DOI 10.1016/j.arth.2020.05.049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Stability of the Porous Tantalum Components Used in Revision THA to Treat Severe Acetabular Defects: A Radiostereometric Analysis Study.

    Solomon, Lucian B / Abrahams, John M / Callary, Stuart A / Howie, Donald W

    The Journal of bone and joint surgery. American volume

    2018  Volume 100, Issue 22, Page(s) 1926–1933

    Abstract: Background: The acetabular components used in revision total hip arthroplasty (THA) to treat severe acetabular bone defects have high rates of re-revision at mid to long-term follow-up. Early translation of acetabular components used in revision THA is ... ...

    Abstract Background: The acetabular components used in revision total hip arthroplasty (THA) to treat severe acetabular bone defects have high rates of re-revision at mid to long-term follow-up. Early translation of acetabular components used in revision THA is a good predictor of later loosening, and radiostereometric analysis (RSA) is the most sensitive method to measure migration. The objectives of the present study were to use RSA to compare the migration of the porous tantalum acetabular components used to treat severe bone defects with the previously established acceptable proximal translation threshold of ≤1 mm within 2 years, and to determine the effect on migration of the addition of inferior screws through the component into the ischium or pubis.
    Methods: RSA was utilized to measure the migration of 55 porous tantalum components used to treat severe acetabular defects (28 Paprosky IIIA, 27 Paprosky IIIB; 21 hips with pelvic discontinuity) at a mean follow-up of 4 years (range, 2 to 12 years).
    Results: Forty-eight of the 55 components migrated less than the threshold that predicts later loosening (>1 mm) and 50 had not been re-revised at the time of the latest follow-up. Seven components, none of which had inferior screw fixation, exceeded the translation threshold. Of these, 6 were implanted to treat pelvic discontinuity. Of those 6 components, 5 were re-revised for loosening related to patient symptoms. At 2 years, the absolute median proximal translation of components with inferior screw fixation was |0.3| mm (range, |0.1| to |0.9| mm), compared with |0.4| mm (range, |0.03| to |16.4| mm) for those without inferior screws (p = 0.04).
    Conclusions: As measured with use of RSA, the majority of porous tantalum acetabular components used in a revision THA to treat severe acetabular defects had acceptable early migration. This predicts good long-term survivorship of these components. The use of inferior screws further improved acetabular component fixation.
    Level of evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
    MeSH term(s) Acetabulum/surgery ; Adult ; Aged ; Aged, 80 and over ; Arthroplasty, Replacement, Hip ; Bone Diseases/surgery ; Foreign-Body Migration/diagnostic imaging ; Hip Prosthesis ; Humans ; Middle Aged ; Porosity ; Prospective Studies ; Prosthesis Design ; Prosthesis Failure ; Radiostereometric Analysis ; Reoperation ; Severity of Illness Index ; Tantalum
    Chemical Substances Tantalum (6424HBN274)
    Language English
    Publishing date 2018-11-27
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 220625-0
    ISSN 1535-1386 ; 0021-9355
    ISSN (online) 1535-1386
    ISSN 0021-9355
    DOI 10.2106/JBJS.18.00127
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The variation in hip stability measurements between supine and standing radiographs of dysplastic hips.

    Bhanushali, Ameya / Chimutengwende-Gordon, Mukai / Beck, Martin / Callary, Stuart Adam / Costi, Kerry / Howie, Donald W / Solomon, Lucian Bogdan

    The bone & joint journal

    2021  Volume 103-B, Issue 11, Page(s) 1662–1668

    Abstract: Aims: The aims of this study were to compare clinically relevant measurements of hip dysplasia on radiographs taken in the supine and standing position, and to compare Hip2Norm software and Picture Archiving and Communication System (PACS)-derived ... ...

    Abstract Aims: The aims of this study were to compare clinically relevant measurements of hip dysplasia on radiographs taken in the supine and standing position, and to compare Hip2Norm software and Picture Archiving and Communication System (PACS)-derived digital radiological measurements.
    Methods: Preoperative supine and standing radiographs of 36 consecutive patients (43 hips) who underwent periacetabular osteotomy surgery were retrospectively analyzed from a single-centre, two-surgeon cohort. Anterior coverage (AC), posterior coverage (PC), lateral centre-edge angle (LCEA), acetabular inclination (AI), sharp angle (SA), pelvic tilt (PT), retroversion index (RI), femoroepiphyseal acetabular roof (FEAR) index, femoroepiphyseal horizontal angle (FEHA), leg length discrepancy (LLD), and pelvic obliquity (PO) were analyzed using both Hip2Norm software and PACS-derived measurements where applicable.
    Results: Analysis of supine and standing radiographs resulted in significant variation for measurements of PT (p < 0.001) and AC (p = 0.005). The variation in PT correlated with the variation in AC in a limited number of patients (R
    Conclusion: The significant variation in PT and AC between supine and standing radiographs suggests that it may benefit surgeons to have both radiographs when planning surgical correction of hip dysplasia. We also recommend using PACS-derived measurements of AI and SA due to the poor interobserver error on Hip2Norm. Cite this article:
    MeSH term(s) Adolescent ; Adult ; Female ; Hip Dislocation/diagnostic imaging ; Humans ; Male ; Middle Aged ; Radiography ; Retrospective Studies ; Standing Position ; Supine Position ; Young Adult
    Language English
    Publishing date 2021-10-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2697156-2
    ISSN 2049-4408 ; 2049-4394
    ISSN (online) 2049-4408
    ISSN 2049-4394
    DOI 10.1302/0301-620X.103B11.BJJ-2020-2519.R2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cemented Revision Hip Arthroplasty With Femoral Impaction Bone Grafting.

    Chimutengwende-Gordon, Mukai / Baker, Markus P / Jagiello, Jakub / Stamenkov, Roumen / Callary, Stuart A / Smitham, Peter / Howie, Donald W / Solomon, Lucian B

    The Journal of the American Academy of Orthopaedic Surgeons

    2021  Volume 29, Issue 14, Page(s) 591–595

    Abstract: Long-stemmed uncemented implants are commonly used during revision hip arthroplasty but may be difficult to re-revise. Impaction bone grafting allows for the use of a shorter cemented stem during revision hip arthroplasty and may restore bone stock in ... ...

    Abstract Long-stemmed uncemented implants are commonly used during revision hip arthroplasty but may be difficult to re-revise. Impaction bone grafting allows for the use of a shorter cemented stem during revision hip arthroplasty and may restore bone stock in patients with substantial femoral defects. Femoral impaction bone grafting is particularly beneficial in younger patients, who are more likely to require additional revision procedures in the future. The surgical technique used at our institution includes improvements to previous methods including the use of modular tamps and nonirradiated, size-profiled bone graft.
    MeSH term(s) Arthroplasty, Replacement, Hip ; Bone Cements ; Bone Transplantation ; Hip Prosthesis ; Humans ; Prosthesis Failure ; Reoperation
    Chemical Substances Bone Cements
    Language English
    Publishing date 2021-06-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200524-1
    ISSN 1940-5480 ; 1067-151X
    ISSN (online) 1940-5480
    ISSN 1067-151X
    DOI 10.5435/JAAOS-D-20-00481
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Wear Rate of Highly Cross-Linked Polyethylene in Total Hip Replacement Is Not Increased by Large Articulations: A Randomized Controlled Trial.

    Howie, Donald W / Holubowycz, Oksana T / Callary, Stuart A

    The Journal of bone and joint surgery. American volume

    2016  Volume 98, Issue 21, Page(s) 1786–1793

    Abstract: Background: Larger articulations reduce the risk of dislocation following primary total hip arthroplasty, leading to increased use of these articulations. The wear rate of highly cross-linked polyethylene (XLPE) is low in standard-diameter articulations ...

    Abstract Background: Larger articulations reduce the risk of dislocation following primary total hip arthroplasty, leading to increased use of these articulations. The wear rate of highly cross-linked polyethylene (XLPE) is low in standard-diameter articulations but remains unclear in larger articulations. The aim of this randomized controlled trial was to compare the mean wear rates of 36-mm and 28-mm metal-on-XLPE articulations between 1 and 3 years postoperatively.
    Methods: Fifty-six elderly patients undergoing primary total hip arthroplasty were randomized intraoperatively to receive either a 36-mm or 28-mm metal-on-XLPE articulation. Factors that may affect wear were controlled by study design. Wear was measured using radiostereometric analysis.
    Results: Mean annual proximal wear rates between 1 and 3 years were 0.00 and 0.01 mm/yr for the 36 and 28-mm articulation cohorts, respectively. No patient had a proximal wear rate of >0.1 mm/yr. Mean wear was very low in all directions, and the wear rate of 36-mm articulations was not significantly greater than that of 28-mm articulations on the basis of proximal, medial 2-dimensional, and 3-dimensional wear.
    Conclusions: The wear rate of a larger 36-mm metal-on-XLPE articulation between 1 and 3 years following primary total hip arthroplasty was low and no greater than that of a 28-mm articulation. However, before a 36-mm metal-on-XLPE articulation is widely recommended, particularly in young active patients, long-term wear rates and association between wear and periprosthetic osteolysis should be determined.
    Level of evidence: Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence.
    MeSH term(s) Aged ; Arthroplasty, Replacement, Hip ; Female ; Hip Joint/surgery ; Hip Prosthesis ; Humans ; Male ; Osteoarthritis, Hip/surgery ; Polyethylene ; Prosthesis Design ; Prosthesis Failure ; Stress, Mechanical ; Treatment Outcome
    Chemical Substances Polyethylene (9002-88-4)
    Language English
    Publishing date 2016-11-02
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Comment
    ZDB-ID 220625-0
    ISSN 1535-1386 ; 0021-9355
    ISSN (online) 1535-1386
    ISSN 0021-9355
    DOI 10.2106/JBJS.15.01248
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Surgical Technique to Manage Periprosthetic Fractures of the Knee in Patients with Infected Leg Ulcers: A Report of Two Cases.

    Smitham, Peter J / Vohora, Ashray / Howie, Donald W / Atkins, Gerald J / Solomon, Lucian B

    JBJS case connector

    2019  Volume 9, Issue 3, Page(s) e0347

    Abstract: Cases: We describe 2 cases of nonagenarians with periprosthetic knee fractures that were not amenable to either standard internal fixation nor prosthesis revision because of infected leg ulcers in the same limb. The fractures were internally fixed by ... ...

    Abstract Cases: We describe 2 cases of nonagenarians with periprosthetic knee fractures that were not amenable to either standard internal fixation nor prosthesis revision because of infected leg ulcers in the same limb. The fractures were internally fixed by percutaneous insertion of medial and lateral plates that spanned the knee. Both patients returned to their baseline level of activity without developing surgical site infections.
    Conclusions: Percutaneous bridging plates that span the knee are a useful option for treating these difficult cases.
    MeSH term(s) Aged, 80 and over ; Female ; Fracture Fixation, Internal/instrumentation ; Fracture Fixation, Internal/methods ; Humans ; Infections/complications ; Knee Injuries/complications ; Knee Injuries/surgery ; Leg Ulcer/complications ; Periprosthetic Fractures/complications ; Periprosthetic Fractures/surgery
    Language English
    Publishing date 2019-08-12
    Publishing country United States
    Document type Case Reports ; Journal Article
    ISSN 2160-3251
    ISSN (online) 2160-3251
    DOI 10.2106/JBJS.CC.18.00347
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Acetabular Component Migration Measured Using Radiostereometric Analysis Following Revision Total Hip Arthroplasty: A Scoping Review.

    Abrahams, John M / Callary, Stuart A / Munn, Zachary / Jang, Sung Won / Huang, Qiang / Howie, Donald W / Solomon, Lucian Bogdan

    JBJS reviews

    2020  Volume 8, Issue 4, Page(s) e0170

    MeSH term(s) Acetabulum/diagnostic imaging ; Arthroplasty, Replacement, Hip/adverse effects ; Arthroplasty, Replacement, Hip/instrumentation ; Hip Prosthesis/adverse effects ; Humans ; Postoperative Complications/diagnostic imaging ; Radiostereometric Analysis ; Reoperation/adverse effects
    Language English
    Publishing date 2020-04-17
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2329-9185
    ISSN (online) 2329-9185
    DOI 10.2106/JBJS.RVW.19.00170
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Accuracy of EBRA-cup measurements after reconstruction of severe acetabular defects at revision THR.

    Abrahams, John M / Callary, Stuart A / Jang, Sung W / Hewitt, Joseph / Howie, Donald W / Solomon, Lucian B

    Journal of orthopaedic research : official publication of the Orthopaedic Research Society

    2020  Volume 38, Issue 7, Page(s) 1497–1505

    Abstract: Radiostereometric analysis (RSA) is the most accurate method of measuring component migration using radiographs but is restricted to use in prospective studies. Ein-Bild-Roentgen-analyze (EBRA)-Cup can be used retrospectively, but its accuracy to measure ...

    Abstract Radiostereometric analysis (RSA) is the most accurate method of measuring component migration using radiographs but is restricted to use in prospective studies. Ein-Bild-Roentgen-analyze (EBRA)-Cup can be used retrospectively, but its accuracy to measure component migration following revision is unknown. This study aimed to determine the accuracy of EBRA-Cup measurements of uncemented acetabular component migration after revision total hip replacement (THR). The secondary aim was to compare the number of cases identified using EBRA-Cup and RSA as having proximally migrated above and below 1 mm at 2 years postoperatively. EBRA-Cup measurements were performed on plain antero-posterior pelvic radiographs taken at the same time as RSA radiographs in a prospective cohort of 53 hips undergoing acetabular revision. At 2 years, the mean difference between the RSA and EBRA-Cup measurements for 17 components used to treat pelvic discontinuity was 0.90 mm, significantly greater than the mean difference of 0.28 mm for 36 components without discontinuity (P = .0001). The mean difference between the RSA and EBRA-Cup measurements at 2 years for hips that were reconstructed with an acetabular component alone, 0.28 mm, was significantly lower than hips that were reconstructed with an acetabular component in combination with an augment and/or cage, 0.74 mm (P = .0005). In conclusion, EBRA-Cup can accurately measure migration of uncemented acetabular components used at revision THR. The presence of pelvic discontinuity, and addition of augments and cages, significantly influenced the accuracy of EBRA-Cup measurements. EBRA-Cup and RSA had good agreement on classification of components that migrated proximally above or below 1 mm at 2 years, with 100% sensitivity, and 87% specificity.
    MeSH term(s) Acetabulum/surgery ; Adult ; Aged ; Aged, 80 and over ; Arthroplasty, Replacement, Hip/instrumentation ; Cohort Studies ; Female ; Hip Joint/diagnostic imaging ; Hip Prosthesis ; Humans ; Male ; Middle Aged ; Prosthesis Failure ; Radiostereometric Analysis
    Language English
    Publishing date 2020-02-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605542-4
    ISSN 1554-527X ; 0736-0266
    ISSN (online) 1554-527X
    ISSN 0736-0266
    DOI 10.1002/jor.24623
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Exposure of the superior gluteal neurovascular bundle for the safe application of acetabular reinforcement cages in complex revisions.

    Smitham, Peter J / Kosuge, Dennis / Howie, Donald W / Solomon, Lucian B

    Hip international : the journal of clinical and experimental research on hip pathology and therapy

    2016  Volume 26, Issue 3, Page(s) 307–309

    Abstract: The posterior approach to the hip is the most common extensile approach used, however exposure is limited superiorly by the superior gluteal neurovascular bundle (SGNB). The extra-pelvic course of the SGNB demonstrates variability between individuals, ... ...

    Abstract The posterior approach to the hip is the most common extensile approach used, however exposure is limited superiorly by the superior gluteal neurovascular bundle (SGNB). The extra-pelvic course of the SGNB demonstrates variability between individuals, occasionally located only 1 cm from the acetabular rim. In complex acetabular reconstructions where the application of a reinforcement cage maybe required protecting the SGNB is challenging. The flanges of these cages are designed to sit on the ilium superior to the acetabular rim and to receive screws for fixation. The application of such cages may result in iatrogenic injury to the SGNB by way of forceful retraction or entrapment. We describe a technique that involves exposure and release of the SGNB such that the flanges of cage constructs may be safely applied.
    MeSH term(s) Acetabulum/surgery ; Arthroplasty, Replacement, Hip/adverse effects ; Arthroplasty, Replacement, Hip/methods ; Buttocks/blood supply ; Buttocks/innervation ; Hip Fractures/surgery ; Hip Prosthesis ; Humans ; Intraoperative Complications/prevention & control ; Patient Safety ; Prosthesis Implantation/methods ; Reoperation/adverse effects ; Reoperation/methods ; Risk Assessment
    Language English
    Publishing date 2016-05-16
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1162513-2
    ISSN 1724-6067 ; 1120-7000
    ISSN (online) 1724-6067
    ISSN 1120-7000
    DOI 10.5301/hipint.5000350
    Database MEDical Literature Analysis and Retrieval System OnLINE

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