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  1. Book ; Audio / Video ; Online: Aktuelles aus den NRL des BfR

    Hoyer, Carolin

    2023  

    Keywords Text ; ddc:610
    Language German
    Publishing date 2023-04-18/2023-04-20
    Publishing country de
    Document type Book ; Audio / Video ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Book ; Thesis: Verstärkung der antigenspezifischen T-Zell-Antwort gegen Tetanustoxoid durch einen bispezifischen CD3xNCAM-Antikörper

    Hoyer, Carolin

    2008  

    Author's details vorgelegt von Carolin Hoyer
    Language German
    Size 52 S. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Köln, Univ., Diss., 2008
    HBZ-ID HT015720929
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Online ; Thesis: Auswirkungen der COVID-19-Pandemie auf die Primärversorgung von PatientInnen mit einer akuten zerebrovaskulären Erkrankung

    Weber, Lenja Anita Greta [Verfasser] / Hoyer, Carolin [Akademischer Betreuer]

    2024  

    Author's details Lenja Anita Greta Weber ; Betreuer: Carolin Hoyer
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek Heidelberg
    Publishing place Heidelberg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  4. Article: Pitfalls in the Diagnosis of Posterior Circulation Stroke in the Emergency Setting.

    Hoyer, Carolin / Szabo, Kristina

    Frontiers in neurology

    2021  Volume 12, Page(s) 682827

    Abstract: Posterior circulation stroke (PCS), caused by infarction within the vertebrobasilar arterial system, is a potentially life-threatening condition and accounts for about 20-25% of all ischemic strokes. Diagnosing PCS can be challenging due to the vast area ...

    Abstract Posterior circulation stroke (PCS), caused by infarction within the vertebrobasilar arterial system, is a potentially life-threatening condition and accounts for about 20-25% of all ischemic strokes. Diagnosing PCS can be challenging due to the vast area of brain tissue supplied by the posterior circulation and, as a consequence, the wide range of-frequently non-specific-symptoms. Commonly used prehospital stroke scales and triage systems do not adequately represent signs and symptoms of PCS, which may also escape detection by cerebral imaging. All these factors may contribute to causing delay in recognition and diagnosis of PCS in the emergency context. This narrative review approaches the issue of diagnostic error in PCS from different perspectives, including anatomical and demographic considerations as well as pitfalls and problems associated with various stages of prehospital and emergency department assessment. Strategies and approaches to improve speed and accuracy of recognition and early management of PCS are outlined.
    Language English
    Publishing date 2021-07-14
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2021.682827
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Audio / Video ; Online: Determination of quinolizidine alkaloids (QA) in food and feed with LC-MS/MS

    Kappenstein, Oliver / Seele, Yannick / Hoyer, Carolin

    Results of the implementation part of a method validation study

    2023  

    Keywords Text ; ddc:610
    Language English
    Publishing date 2023-06-19/2023-06-23
    Publishing country de
    Document type Book ; Audio / Video ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Epidemiologische Untersuchung zu möglichen Auswirkungen öffentlicher Kommunikation im Rahmen der COVID-19-Pandemie auf Notfallvorstellungen von Kopfschmerzpatient*innen.

    Wittayer, Matthias / Sandikci, Vesile / Ebert, Anne / Koehler, Clemens / Szabo, Kristina / Hoyer, Carolin

    Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))

    2023  Volume 86, Issue 3, Page(s) 232–236

    Abstract: Headache is a frequent presenting symptom in the emergency department. While most cases are of benign aetiology, it is crucially important to identify potentially dangerous underlying disorders. We hypothesized an increase in headache-related emergency ... ...

    Title translation Potential Impact of Public Communication on Emergency Presentations due to Headache during the Covid-19 Pandemic.
    Abstract Headache is a frequent presenting symptom in the emergency department. While most cases are of benign aetiology, it is crucially important to identify potentially dangerous underlying disorders. We hypothesized an increase in headache-related emergency presentations after venous thrombosis of cerebral sinuses had been identified as a rare side effect of vaccination with adenovirus vector-based Coronavirus-disease 2019 (COVID-19) vaccines and that information had been publicly communicated by the Paul Ehrlich Institute. Data from patients with the diagnosis of primary headache disorders or unspecified headache presenting to the Interdisciplinary Emergency Department of the University Medicine Mannheim were retrospectively analysed. Based on vaccination dashboard data published by the Federal Ministry of Health, calendar weeks 14-30 and 47-48, on the one hand, and 1-13 and 31-46, on the othe, were categorized into a variable "vaccination epoch" (14-30, 47-48: high vaccination activity if≥3 million weekly vaccinations in Germany; 1-13, 31-46: low vaccination activity if<3 million weekly vaccinations). The number of patients with headache was the dependent variable. A Poisson regression was performed to analyze whether the frequency of events, i. e., patient presentations, was a function of year (2019, 2021), epoch (high, low) and an interaction of year and epoch - the latter reflecting an impact of vaccination activity during the pandemic and expressed as incidence rate ratio. Compared to 2019, there was a more than 70% increase in presentations due to headache during periods of high vaccination activity in 2021 (p<0.001; 95% confidence interval 1.272-2.316), in 25% of presentations in 2021, patients considered their headache as vaccination-associated. Public communication and resulting nocebo effects may, among other factors, have contributed to our observation of increased numbers of emergency headache presentations, illustrating the impact of public distribution of medical information on practical aspects of emergency care during crises.
    MeSH term(s) Humans ; COVID-19/epidemiology ; Pandemics ; Retrospective Studies ; Germany ; Headache/diagnosis ; Headache/epidemiology ; Headache/etiology ; Vaccination ; Communication ; Emergency Service, Hospital
    Language German
    Publishing date 2023-12-08
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 1101426-x
    ISSN 1439-4421 ; 0941-3790 ; 0949-7013
    ISSN (online) 1439-4421
    ISSN 0941-3790 ; 0949-7013
    DOI 10.1055/a-2146-6286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Ultrafast photogeneration of a metal-organic nitrene from 1,1'-diazidoferrocene.

    Scherz, Frederik / Bauer, Markus / Domenianni, Luis I / Hoyer, Carolin / Schmidt, Jonas / Sarkar, Biprajit / Vöhringer, Peter / Krewald, Vera

    Chemical science

    2024  Volume 15, Issue 18, Page(s) 6707–6715

    Abstract: Ferrocene and its derivatives have fascinated chemists for more than 70 years, not least due to the analogies with the properties of benzene. Despite these similarities, the obvious difference between benzene and ferrocene is the presence of an iron ion ... ...

    Abstract Ferrocene and its derivatives have fascinated chemists for more than 70 years, not least due to the analogies with the properties of benzene. Despite these similarities, the obvious difference between benzene and ferrocene is the presence of an iron ion and hence the availability of d-orbitals for properties and reactivity. Phenylnitrene with its rich photochemistry can be considered an analogue of nitrenoferrocene. As with most organic and inorganic nitrenes, nitrenoferrocene can be obtained by irradiating the azide precursor. We study the photophysical and photochemical processes of dinitrogen release from 1,1'-diazidoferrocene to form 1-azido-1'-nitrenoferrocene with UV-pump-mid-IR-probe transient absorption spectroscopy and time-dependent density functional theory calculations including spin-orbit coupling. An intermediate with a bent azide moiety is identified that is pre-organised for dinitrogen release
    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d4sc00883a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Klinik, Diagnostik und Pathophysiologie der transienten globalen Amnesie (TGA)

    Hoyer, Carolin / Szabo, Kristina

    Neurologie up2date

    2020  Volume 3, Issue 03, Page(s) 259–270

    Language German
    Publishing date 2020-08-01
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ISSN 2511-3658 ; 2511-3453
    ISSN (online) 2511-3658
    ISSN 2511-3453
    DOI 10.1055/a-0948-7329
    Database Thieme publisher's database

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  9. Article ; Online: Impaired semantic memory during acute transient global amnesia.

    Sandikci, Vesile / Ebert, Anne / Hoyer, Carolin / Platten, Michael / Szabo, Kristina

    Journal of neuropsychology

    2021  Volume 16, Issue 1, Page(s) 149–160

    Abstract: As a clinical model of hippocampal dysfunction, transient global amnesia (TGA) causes reversible memory disturbance. While episodic memory deficits in TGA patients have been extensively described, data regarding semantic memory involvement are sparse and ...

    Abstract As a clinical model of hippocampal dysfunction, transient global amnesia (TGA) causes reversible memory disturbance. While episodic memory deficits in TGA patients have been extensively described, data regarding semantic memory involvement are sparse and contradictory. We report impaired semantic fluency performance in 16 patients with hippocampal lesions on MRI during acute TGA compared to their performance one day later and to that of 20 healthy subjects. Our findings support the involvement of the hippocampus in semantic retrieval.
    MeSH term(s) Amnesia, Transient Global/complications ; Hippocampus ; Humans ; Memory Disorders/etiology ; Memory, Episodic ; Semantics
    Language English
    Publishing date 2021-05-21
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2380753-2
    ISSN 1748-6653 ; 1748-6645
    ISSN (online) 1748-6653
    ISSN 1748-6645
    DOI 10.1111/jnp.12251
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Sex-related differences in stressful events precipitating transient global amnesia - A retrospective observational study.

    Hoyer, Carolin / Ebert, Anne / Sandikci, Vesile / Platten, Michael / Szabo, Kristina

    Journal of the neurological sciences

    2021  Volume 425, Page(s) 117464

    Abstract: Introduction: Physically or emotionally charged events have consistently been reported as precipitating an episode of transient global amnesia (TGA). In conjunction with evidence of hippocampal involvement from neuroimaging, this has promoted the ... ...

    Abstract Introduction: Physically or emotionally charged events have consistently been reported as precipitating an episode of transient global amnesia (TGA). In conjunction with evidence of hippocampal involvement from neuroimaging, this has promoted the hypothesis that TGA is a stress-related disorder.
    Methods: In this retrospective observational study, medical records of 389 patients with TGA were analysed regarding documented precipitating events, which were classified according to previously suggested criteria. Moreover, comorbidities and results of magnetic resonance imaging were collected.
    Findings: In our cohort of TGA patients, 231 were female (59.4%). A precipitating factor was identified in 266 patients (68.4%). Of these, 136 patients (51.1%) reported physical triggers, the most common being physical exertion (64.0%). Another 122 patients (45.9%) presented with an emotional trigger, most frequently classified as an interpersonal conflict (42.7%). In 8 cases (2.1%), TGA was preceded by a medical procedure. Emotional triggers were more often experienced by women (37.2% vs 22.8%, p = 0.003), while physical stressors were more often present in men (30.7% vs 41.1%, p = 0.035). Women had a significantly higher number of hippocampal MRI lesions than men (mean 1.13 vs 0.92; p = 0.042).
    Conclusion: Our data suggest a female predominance in TGA occurrence and a sex-related difference in susceptibility to certain triggering events in TGA patients. In light of recent research on sex-specific differences in vulnerability to stress, these findings support the hypothesis that this might be a significant contributing factor in the pathogenesis of TGA.
    MeSH term(s) Amnesia, Transient Global/diagnostic imaging ; Amnesia, Transient Global/epidemiology ; Amnesia, Transient Global/etiology ; Emotions ; Female ; Hippocampus ; Humans ; Magnetic Resonance Imaging ; Male ; Retrospective Studies
    Language English
    Publishing date 2021-04-17
    Publishing country Netherlands
    Document type Journal Article ; Observational Study
    ZDB-ID 80160-4
    ISSN 1878-5883 ; 0022-510X ; 0374-8642
    ISSN (online) 1878-5883
    ISSN 0022-510X ; 0374-8642
    DOI 10.1016/j.jns.2021.117464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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