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Article ; Online: Use of Intrinsic Entropy to Assess the Instantaneous Complexity of Thoracoabdominal Movement Patterns to Indicate the Effect of the Iso-Volume Maneuver Trial on the Performance of the Step Test.

Huang, Po-Hsun / Hsiao, Tzu-Chien

2023 Volume 26, Issue 1

Abstract: The recent surge in interest surrounds the analysis of physiological signals with a non-linear dynamic approach. The measurement of entropy serves as a renowned method for indicating the complexity of a signal. However, there is a dearth of research ... ...

Abstract	The recent surge in interest surrounds the analysis of physiological signals with a non-linear dynamic approach. The measurement of entropy serves as a renowned method for indicating the complexity of a signal. However, there is a dearth of research concerning the non-linear dynamic analysis of respiratory signals. Therefore, this study employs a novel method known as intrinsic entropy (IE) to assess the short-term dynamic changes in thoracoabdominal movement patterns, as measured by respiratory inductance plethysmography (RIP), during various states such as resting, step test, recovery, and iso-volume maneuver (IVM) trials. The findings reveal a decrease in IE of thoracic wall movement (TWM) and an increase in IE of abdominal wall movement (AWM) following the IVM trial. This suggests that AWM may dominate the breathing exercise after the IVM trial. Moreover, due to the high temporal resolution of IE, it proves to be a suitable measure for assessing the complexity of thoracoabdominal movement patterns under non-stationary states such as the step test and recovery. The results also demonstrate that the instantaneous complexity of TWM and AWM can effectively capture instantaneous changes during non-stationary states, which may prove valuable in understanding the respiratory mechanism for healthcare purposes in daily life.
Language	English
Publishing date	2023-12-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2014734-X
ISSN	1099-4300 ; 1099-4300
ISSN (online)	1099-4300
ISSN	1099-4300
DOI	10.3390/e26010027
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Extended classifier system with continuous real-coded variables for feature extraction of instantaneous pulse-rate variability and respiration of individuals with gaming disorder.

Chi, Hung-Ming / Hsiao, Tzu-Chien

Biomedical engineering online

2021 Volume 20, Issue 1, Page(s) 93

Abstract: Background: Individuals with gaming disorder (GD) exhibit autonomic nervous system responses that indicate dysfunctional emotion regulation. Pulse rate variability (PRV) is a valuable biomarker for investigating the autonomic function of patients with ... ...

Abstract	Background: Individuals with gaming disorder (GD) exhibit autonomic nervous system responses that indicate dysfunctional emotion regulation. Pulse rate variability (PRV) is a valuable biomarker for investigating the autonomic function of patients with mental disorders. Because individuals with GD dynamically regulate emotions during gaming, the PRV response relating to GD is not well understood. To investigate the dynamic PRV responses of individuals with GD, this study proposed the indexes of instantaneous PRV (iPRV) and instantaneous respiratory frequency (IF Results: A total of 32 college students without depressive and anxiety symptoms or cardiovascular diseases were recruited in this study. Participants were grouped into the high-risk GD and low-risk GD using both Chen Internet Addiction Scale and Internet Gaming Disorder Questionnaire. Their arterial blood pressures signals were measured while they watched gameplay videos with negative or positive emotional stimuli. Seven participants with high-risk GD exhibited significantly increased normalized VHF (nVHF) PRV and IF Conclusions: iPRV and IF
MeSH term(s)	Algorithms ; Autonomic Nervous System ; Behavior, Addictive ; Heart Rate ; Humans ; Respiration
Language	English
Publishing date	2021-09-23
Publishing country	England
Document type	Journal Article
ISSN	1475-925X
ISSN (online)	1475-925X
DOI	10.1186/s12938-021-00930-3
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Article ; Online: The Indices of Instantaneous Pulse Rate Variability Are Indicators for Daily Life Quality Assessment in Patients with COPD.

Huang, Po-Hsun / Luo, Yi-Fei / Hsiao, Tzu-Chien

Journal of healthcare engineering

2022 Volume 2022, Page(s) 6103305

Abstract: Chronic obstructive pulmonary disease (COPD) is a progressive respiratory illness. Questionnaires such as modified Medical Research Council (mMRC) dyspnea scale and COPD assessment test (CAT) are useful for COPD condition and life quality assessment. ... ...

Abstract	Chronic obstructive pulmonary disease (COPD) is a progressive respiratory illness. Questionnaires such as modified Medical Research Council (mMRC) dyspnea scale and COPD assessment test (CAT) are useful for COPD condition and life quality assessment. These questionnaires reflect how respiratory disorder affects daily life. Breathing and autonomic nervous system (ANS) usually regulate each other. Few studies discussed the ANS activity and daily life quality in patients with COPD. Therefore, this study aimed to find the relationship between daily life quality assessed by mMRC or CAT and ANS assessed by a novel method, instantaneous pulse rate variability (iPRV), a method indicating not only the ANS activity but also the peripheral response. The result showed that the change in mMRC and the change in low frequency power to high frequency power ratio, which usually represents the sympathetic activity in conventional heart rate variability analysis, had significant correlation (
MeSH term(s)	Autonomic Nervous System ; Heart Rate ; Humans ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Quality of Life ; Respiratory Rate
Language	English
Publishing date	2022-02-10
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2545054-2
ISSN	2040-2309 ; 2040-2295
ISSN (online)	2040-2309
ISSN	2040-2295
DOI	10.1155/2022/6103305
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Article ; Online: Instantaneous Respiratory Response of Gamer with High-Risk Internet Gaming Disorder during Game-Film Stimuli by Using Complementary Ensemble Empirical Mode Decomposition.

Ji, Hong-Ming / Hsiao, Tzu-Chien

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

2020 Volume 2020, Page(s) 980–983

Abstract: Gamers with Internet gaming disorder (IGD) dynamically regulate their psychophysiological responses during playing; however, analyzing instantaneous psychophysiological responses in these gamers has been limited by a lack of appropriate methods. We ... ...

Abstract	Gamers with Internet gaming disorder (IGD) dynamically regulate their psychophysiological responses during playing; however, analyzing instantaneous psychophysiological responses in these gamers has been limited by a lack of appropriate methods. We propose combining the Complementary Ensemble Empirical Mode Decomposition and Direct Quadrature methods to overcome this limitation. The related effect of abdominal breathing (AB) training (as a relaxing psychology method) on the distribution of instantaneous frequency (IF) was investigated by calculating median (IF
MeSH term(s)	Behavior, Addictive ; Disruptive, Impulse Control, and Conduct Disorders ; Humans ; Internet ; Role Playing ; Video Games
Language	English
Publishing date	2020-10-05
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2694-0604
ISSN (online)	2694-0604
DOI	10.1109/EMBC44109.2020.9175719
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Article ; Online: A Novel Cue-Induced Abdominal Reaction Analysis for Internet Gaming Disorder.

Ji, Hong-Ming / Hsiao, Tzu-Chien

Journal of medical systems

2019 Volume 43, Issue 4, Page(s) 94

Abstract: Individuals with Internet gaming disorder (IGD) frequently play online games to achieve satisfaction. Numerous signal processing questions regarding the negative consequences and characteristic respiration in a long-term sitting posture remain unanswered. ...

Abstract	Individuals with Internet gaming disorder (IGD) frequently play online games to achieve satisfaction. Numerous signal processing questions regarding the negative consequences and characteristic respiration in a long-term sitting posture remain unanswered. This study recruited 50 individuals with high-risk and low-risk IGD (HIGD and LIGD); these participants were taught to perform a specific respiration during game-film stimuli. The instantaneous frequencies on abdominal movement (f
MeSH term(s)	Abdomen/physiology ; Adult ; Behavior, Addictive/physiopathology ; Cues ; Emotions/physiology ; Female ; Humans ; Internet ; Male ; Respiration ; Respiratory Mechanics/physiology ; Rest/physiology ; Risk Factors ; Video Games ; Young Adult
Language	English
Publishing date	2019-03-05
Publishing country	United States
Document type	Clinical Trial ; Journal Article
ZDB-ID	423488-1
ISSN	1573-689X ; 0148-5598
ISSN (online)	1573-689X
ISSN	0148-5598
DOI	10.1007/s10916-019-1221-9
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Zs.A 1426: Show issues

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Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Classification of the risk of internet gaming disorder by flow short scale and cardiovascular response.

Lai, Yu-Han / Chi, Hung-Ming / Huang, Po-Hsun / Hsiao, Tzu-Chien

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

2021 Volume 2021, Page(s) 1761–1764

Abstract: The American Psychiatric Association has identified Internet gaming disorder (IGD) as a potential psychiatric disorder. Questionnaires are the main method to classify high-risk IGD (HIGD) and low-risk IGD (LIGD). However, the results obtained using ... ...

Abstract	The American Psychiatric Association has identified Internet gaming disorder (IGD) as a potential psychiatric disorder. Questionnaires are the main method to classify high-risk IGD (HIGD) and low-risk IGD (LIGD). However, the results obtained using questionnaires might be affected due to several factors. Flow can measure a person's state of concentration and cardiovascular signals can reflect the autonomic responses of a person. We propose to observe the cardiovascular responses and flow scores from the flow short scale of the HIGD and LIGD groups to assist questionnaires in IGD risk assessment. The preliminary study recruited 18 gamers from colleges. Games with the easy and hard levels were set to arouse desire for playing. The result showed that the flow scores of five HIGD participants were significantly lower compared with that of 13 LIGD participants. The stroke volume (SV) of the LIGD group during baseline (67.06 ± 11.61) was significantly greater that of (p < 0.05) while playing the easy game (64.08 ± 10.37) and playing the hard game (63.70 ± 9.89). For the LIGD group, the cardiac output (CO) during baseline (5.28 ± 0.97) was significantly greater (p < 0.01) than that of recovery (5.03 ± 0.83), and while playing the easy game (5.34 ± 0.98) it was significantly more than that during recovery (p < 0.05). For the HIGD group, a significant difference in the heart rate, SV, and CO was not observed. The changes in cardiovascular responses of the LIGD group are greater than that of the HIGD group. Gamers with LIGD might have a higher susceptibility to the negative effect of playing video games, but gamers with HIGD might not. The finding of this study might help psychologists to estimate the IGD risk.Clinical Relevance- This study investigated the differences in the score of flow short scale, self-assessment manikin, challenge/skill, emotional questionnaire, and the changes in the cardiovascular responses between the HIGD and LIGD groups.
MeSH term(s)	Behavior, Addictive ; Emotions ; Humans ; Internet Addiction Disorder ; Surveys and Questionnaires ; Video Games
Language	English
Publishing date	2021-12-07
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2694-0604
ISSN (online)	2694-0604
DOI	10.1109/EMBC46164.2021.9629642
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Article ; Online: Toward instantaneous frequency of respiration to investigate the risk of internet gaming disorder.

Chiu, Wei-Yu / Chen, Liang-Yu / Chi, Hung-Ming / Hsiao, Tzu-Chien

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

2021 Volume 2021, Page(s) 232–235

Abstract: With the development of Internet, the number of people with symptoms of Internet gaming disorder (IGD) has increased. In the past, psychologists used retrospective questionnaires to diagnose IGD. However, it is difficult to diagnose IGD symptoms ... ...

Abstract	With the development of Internet, the number of people with symptoms of Internet gaming disorder (IGD) has increased. In the past, psychologists used retrospective questionnaires to diagnose IGD. However, it is difficult to diagnose IGD symptoms instantaneously using retrospective questionnaires due to the requirement of an Internet gaming experience of greater than 6 months and the limitations of retrospective memory. Observing the physiological regulation system might instantaneously diagnose IGD. However, observation of instantaneous physiological response is limited due to the lack of appropriate techniques. Our previous study successfully combined complimentary ensemble empirical mode decomposition and normalized direct quadrature to obtain respiratory instantaneous frequency (IF) to overcome this limitation. This study uses game-related films as stimulus materials to observe the difference in respiratory IF response per second of gamers with high-risk IGD (HIGD) and low-risk IGD (LIGD). The result showed that the respiratory IF of gamers with HIGD is lower than those of gamers with LIGD at the time of stimulation. In addition, the study also observes the dynamic change in respiratory IF per second (IF
MeSH term(s)	Behavior, Addictive/diagnosis ; Humans ; Internet Addiction Disorder ; Respiration ; Retrospective Studies ; Video Games
Language	English
Publishing date	2021-12-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2694-0604
ISSN (online)	2694-0604
DOI	10.1109/EMBC46164.2021.9631039
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Article ; Online: Towards estimation of respiratory muscle effort with respiratory inductance plethysmography signals and complementary ensemble empirical mode decomposition.

Chen, Ya-Chen / Hsiao, Tzu-Chien

Medical & biological engineering & computing

2017 Volume 56, Issue 7, Page(s) 1293–1303

Abstract: Respiratory inductance plethysmography (RIP) sensor is an inexpensive, non-invasive, easy-to-use transducer for collecting respiratory movement data. Studies have reported that the RIP signal's amplitude and frequency can be used to discriminate ... ...

Abstract	Respiratory inductance plethysmography (RIP) sensor is an inexpensive, non-invasive, easy-to-use transducer for collecting respiratory movement data. Studies have reported that the RIP signal's amplitude and frequency can be used to discriminate respiratory diseases. However, with the conventional approach of RIP data analysis, respiratory muscle effort cannot be estimated. In this paper, the estimation of the respiratory muscle effort through RIP signal was proposed. A complementary ensemble empirical mode decomposition method was used, to extract hidden signals from the RIP signals based on the frequency bands of the activities of different respiratory muscles. To validate the proposed method, an experiment to collect subjects' RIP signal under thoracic breathing (TB) and abdominal breathing (AB) was conducted. The experimental results for both the TB and AB indicate that the proposed method can be used to loosely estimate the activities of thoracic muscles, abdominal muscles, and diaphragm. Graphical abstract ᅟ.
MeSH term(s)	Algorithms ; Female ; Humans ; Male ; Plethysmography ; Respiration ; Respiratory Muscles/physiology ; Signal Processing, Computer-Assisted ; Young Adult
Language	English
Publishing date	2017-12-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	282327-5
ISSN	1741-0444 ; 0025-696X ; 0140-0118
ISSN (online)	1741-0444
ISSN	0025-696X ; 0140-0118
DOI	10.1007/s11517-017-1766-z
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Zs.A 294: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Instantaneous phase difference analysis between thoracic and abdominal movement signals based on complementary ensemble empirical mode decomposition.

Chen, Ya-Chen / Hsiao, Tzu-Chien

Biomedical engineering online

2016 Volume 15, Issue 1, Page(s) 112

Abstract: Background: Thoracoabdominal asynchrony is often adopted to discriminate respiratory diseases in clinics. Conventionally, Lissajous figure analysis is the most frequently used estimation of the phase difference in thoracoabdominal asynchrony. However, ... ...

Abstract	Background: Thoracoabdominal asynchrony is often adopted to discriminate respiratory diseases in clinics. Conventionally, Lissajous figure analysis is the most frequently used estimation of the phase difference in thoracoabdominal asynchrony. However, the temporal resolution of the produced results is low and the estimation error increases when the signals are not sinusoidal. Other previous studies have reported time-domain procedures with the use of band-pass filters for phase-angle estimation. Nevertheless, the band-pass filters need calibration for phase delay elimination. Methods: To improve the estimation, we propose a novel method (named as instantaneous phase difference) that is based on complementary ensemble empirical mode decomposition for estimating the instantaneous phase relation between measured thoracic wall movement and abdominal wall movement. To validate the proposed method, experiments on simulated time series and human-subject respiratory data with two breathing types (i.e., thoracic breathing and abdominal breathing) were conducted. Latest version of Lissajous figure analysis and automatic phase estimation procedure were compared. Results: The simulation results show that the standard deviations of the proposed method were lower than those of two other conventional methods. The proposed method performed more accurately than the two conventional methods. For the human-subject respiratory data, the results of the proposed method are in line with those in the literature, and the correlation analysis result reveals that they were positively correlated with the results generated by the two conventional methods. Furthermore, the standard deviation of the proposed method was also the smallest. Conclusions: To summarize, this study proposes a novel method for estimating instantaneous phase differences. According to the findings from both the simulation and human-subject data, our approach was demonstrated to be effective. The method offers the following advantages: (1) improves the temporal resolution, (2) does not introduce a phase delay, (3) works with non-sinusoidal signals, (4) provides quantitative phase estimation without estimating the embedded frequency of breathing signals, and (5) works without calibrated measurements. The results demonstrate a higher temporal resolution of the phase difference estimation for the evaluation of thoracoabdominal asynchrony.
MeSH term(s)	Abdominal Wall/physiology ; Female ; Humans ; Male ; Movement ; Respiration ; Signal Processing, Computer-Assisted ; Thoracic Wall/physiology ; Time Factors ; Young Adult
Language	English
Publishing date	2016-10-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2084374-4
ISSN	1475-925X ; 1475-925X
ISSN (online)	1475-925X
ISSN	1475-925X
DOI	10.1186/s12938-016-0233-7
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Article ; Online: Respiratory sinus arrhythmia reactivity of internet addiction abusers in negative and positive emotional states using film clips stimulation.

Hsieh, Dai-Ling / Hsiao, Tzu-Chien

Biomedical engineering online

2016 Volume 15, Issue 1, Page(s) 69

Abstract: Background and aims: People with internet addiction (IA) suffer from mental, physical, social, and occupational problems. IA includes psychological and physiological syndromes, and among the syndromes, emotion was suggested important mental and ... ...

Abstract	Background and aims: People with internet addiction (IA) suffer from mental, physical, social, and occupational problems. IA includes psychological and physiological syndromes, and among the syndromes, emotion was suggested important mental and physiological expressions of IA. However, few physiologically emotional characters of IA were investigated. Autonomic nervous system (ANS) activity was a good link between IA and emotion, and respiratory sinus arrhythmia (RSA) gained from ANS was hypothesized related to IA. Methods: An emotional induction experiment using negative and positive emotional films was conducted to validate the hypotheses. Thirty-four participants recruited from college were classified into high-risk IA group (HIA) and low-risk IA group (LIA). The respiratory signals, ECG signals, and self-assessed emotional intensity were acquired. The relationship and difference between IA and RSA was tested using descriptive statistics and inferential statistics. Results: The RSA values of HIA were lower than those of LIA both before and after the induction of positive and negative emotions. When participants experienced a negative emotion (anger or fear), their RSA values declined; the decline for HIA was greater than that for LIA. The RSA values of HIA participants before induction of fear, happiness, or surprise, statistically significantly differed from that after induction of those emotions, with p values of 0.007, 0.04 and 0.01 respectively. The difference between the changes in RSA values upon the induction of surprise of HIA and LIA was statistically significant difference (p = 0.03). The interaction between two IA groups among emotional induction states was statistically significant difference. Conclusions: RSA value here was the main variable that reflected ANS activity, and especially vagus nerve regulation. The results revealed that the changes in RSA values were biologically significantly different between HIA and LIA, especially when sadness, happiness, or surprise was induced. HIA people exhibited stronger RSA reactivity following negative emotion than LIA people, but the RSA reactivity following positive emotion was weaker. This study provides more physiological information about IA and assists further investigation on the regulation of the ANS for IA abusers. The results will benefit the further application, early detection, therapy, and even early prevention. Clinical trial registration details This study was approved by the Institution Review Board of the National Taiwan University Hospital, Hsinchu Branch (Hsinchu, Taiwan), under the research project: A study of interactions between cognition, emotion and physiology (contract no.100IRB-32).
MeSH term(s)	Adult ; Analysis of Variance ; Behavior, Addictive/physiopathology ; Behavior, Addictive/psychology ; Emotions ; Female ; Humans ; Internet ; Linear Models ; Male ; Motion Pictures ; Photic Stimulation ; Respiratory Sinus Arrhythmia ; Risk ; Young Adult
Language	English
Publishing date	2016-07-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2084374-4
ISSN	1475-925X ; 1475-925X
ISSN (online)	1475-925X
ISSN	1475-925X
DOI	10.1186/s12938-016-0201-2
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