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  1. Article ; Online: Non-mesh inguinal hernia repair with early resumption of peritoneal dialysis in patients on continuous ambulatory peritoneal dialysis.

    Hsieh, Tsung-Yi / Lin, Hsiu-Ying / Huang, Kuo-How

    Hernia : the journal of hernias and abdominal wall surgery

    2024  Volume 28, Issue 2, Page(s) 615–620

    Abstract: Purpose: Inguinal hernia is a common complication of peritoneal dialysis (PD). Although tension-free mesh repair is a leading option for inguinal hernia repair, concerns over serious mesh-related complications may indicate a role for non-mesh inguinal ... ...

    Abstract Purpose: Inguinal hernia is a common complication of peritoneal dialysis (PD). Although tension-free mesh repair is a leading option for inguinal hernia repair, concerns over serious mesh-related complications may indicate a role for non-mesh inguinal hernia repair. In addition, there is no consensus on the perioperative dialysis regimen. Early resumption of PD may avoid the additional risks associated with hemodialysis. We report on the outcomes of non-mesh inguinal hernia repair in patients on continuous ambulatory PD (CAPD) and provide a perioperative dialysis protocol that aims to guide early resumption of PD.
    Methods: Between May 2019 and September 2023, thirty CAPD patients with 43 inguinal hernias who underwent non-mesh inguinal hernia repair were retrospectively analyzed. Data on the patient characteristics, perioperative dialysis regimen, perioperative features, complications, and hernia recurrence were collected and assessed.
    Results: Thirty patients with a total of 43 inguinal hernia repairs were included in this study. The median age was 53 years. 23 patients were male and 7 were female. Non-mesh inguinal repair was performed for all patients. PD was resumed at a median of 2 days after the surgery. Five patients received interim hemodialysis. There were no postoperative surgical or uremic complications and no recurrence after a median follow-up of 31.5 months.
    Conclusion: Our study demonstrates the effectiveness and safety of non-mesh repair with early resumption of PD in patients on CAPD. Interim HD is unnecessary in selected patients. Choosing the optimal perioperative dialysis regimen is essential to managing inguinal hernias in CAPD patients.
    MeSH term(s) Humans ; Male ; Female ; Middle Aged ; Hernia, Inguinal/surgery ; Hernia, Inguinal/etiology ; Peritoneal Dialysis, Continuous Ambulatory/adverse effects ; Retrospective Studies ; Herniorrhaphy/adverse effects ; Herniorrhaphy/methods ; Peritoneal Dialysis ; Surgical Mesh/adverse effects
    Language English
    Publishing date 2024-02-19
    Publishing country France
    Document type Journal Article
    ZDB-ID 1388125-5
    ISSN 1248-9204 ; 1265-4906
    ISSN (online) 1248-9204
    ISSN 1265-4906
    DOI 10.1007/s10029-024-02960-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Comparison of senhance and da vinci robotic radical prostatectomy: short-term outcomes, learning curve, and cost analysis.

    Lin, Yen-Chun / Yuan, Lun-Hsiang / Tseng, Chi-Shin / Hsieh, Tsung-Yi / Huang, Yu-Wen / Huang, Chao-Yuan / Huang, Shi-Wei

    Prostate cancer and prostatic diseases

    2023  Volume 27, Issue 1, Page(s) 116–121

    Abstract: Background: The Senhance® Robotic System is a new laparoscopy-based platform that has been increasingly used in radical prostatectomy (RP) procedures. The purpose of this study is to compare the outcome of Senhance RP (SRP) with da Vinci RP (DRP) cases.! ...

    Abstract Background: The Senhance® Robotic System is a new laparoscopy-based platform that has been increasingly used in radical prostatectomy (RP) procedures. The purpose of this study is to compare the outcome of Senhance RP (SRP) with da Vinci RP (DRP) cases.
    Methods: From August 2019 to April 2022, we prospectively recruited 63 cases of SRP. We compared the perioperative data, postoperative complication rates, short-term surgical outcomes (3-month postoperative undetectable prostate-specific antigen (PSA) and incontinence rates), learning curves, and cost analysis with data from 63 matched da Vinci Xi RP cases.
    Results: There was no difference in BL (180 versus 180 ml, p = 0.86) and postoperative surgical complication rate (Clavient -Dindo grade I-IV, 25.3 versus 22.2%, p = 0.21) between the SRP cases and the DRP. Regarding the oncologic and continence function, there was no difference between positive margin rate (36.5% versus 41.3%, p = 0.58), rate of undetectable PSA level at postoperative 3 months (68.3 versus 66.7%, p = 0.85), and incontinence rate (14.3 versus 15.9%, p = 1.0) at postoperative 3 months between the two cohorts. The learning curve showed a quick downward slope for laparoscopic experienced surgeons. The median pocket cost for SRP patients in our hospital was $4170, which was lower than $7675 for the DRP patients.
    Conclusions: Safety and short-term outcomes are comparable between SRP and DRP. For experienced LRP surgeons, using the Senhance system to perform RP is straightforward. With a more affordable price as its biggest advantage, the Senhance system may serve as a safe and effective alternative for robotic RP.
    MeSH term(s) Male ; Humans ; Robotic Surgical Procedures/adverse effects ; Robotic Surgical Procedures/methods ; Learning Curve ; Prostate-Specific Antigen ; Prostatic Neoplasms/surgery ; Prostatic Neoplasms/etiology ; Prostatectomy/methods ; Urinary Incontinence/epidemiology ; Urinary Incontinence/etiology ; Costs and Cost Analysis ; Treatment Outcome
    Chemical Substances Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2023-09-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1419277-9
    ISSN 1476-5608 ; 1365-7852
    ISSN (online) 1476-5608
    ISSN 1365-7852
    DOI 10.1038/s41391-023-00717-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Case Report: Primary Aldosteronism Due to Bilateral Aldosterone-Producing Micronodules With HISTALDO Classical and Contralateral Non-Classical Pathology.

    Chen, Yi-Ju / Peng, Kang-Yung / Chueh, Jeff S / Liao, Hung-Wei / Hsieh, Tsung-Yi / Wu, Vin-Cent / Wang, Shuo-Meng

    Frontiers in endocrinology

    2022  Volume 13, Page(s) 816754

    Abstract: Background: Non-classical multiple aldosterone-producing micronodules/nodules (mAPM/mAPN) could be the pathogenesis of primary aldosteronism (PA). The co-existence of mAPM with adenomas harboring somatic mutations has not previously been reported.: ... ...

    Abstract Background: Non-classical multiple aldosterone-producing micronodules/nodules (mAPM/mAPN) could be the pathogenesis of primary aldosteronism (PA). The co-existence of mAPM with adenomas harboring somatic mutations has not previously been reported.
    Methods: We presented a PA patient with bilateral mAPM and concomitant autonomous cortisol secretion (ACS).
    Results: A 46-year-old Taiwanese woman presented with hypertension, hypokalemia, and bilateral adrenal adenomas. A 1 mg low-dose dexamethasone suppression test showed elevated morning serum cortisol. An adrenal vein sampling (AVS) suggested a left-sided lateralization of hyperaldosteronism. A right partial adrenalectomy and a left total adrenalectomy were performed. The patient showed biochemical and hypertension remission after the operation. This patient had bilateral mAPM with concomitant ACS, a right histopathologically classical PA adenoma, and a left non-classical PA adenoma. The right adrenal adenoma showed CYP11B1-negative and CYP11B2-positive staining and harbored the
    Conclusion: In a PA patient with concomitant ACS, bilateral APM could coexist with both histopathologically classical and non-classical PA adenomas, each with different somatic mutations. The presence of ACS could lead to the misinterpretation of AVS results.
    MeSH term(s) Adenoma/pathology ; Adrenocortical Adenoma/complications ; Adrenocortical Adenoma/genetics ; Adrenocortical Adenoma/surgery ; Aldosterone ; Cytochrome P-450 CYP11B2/metabolism ; Female ; G Protein-Coupled Inwardly-Rectifying Potassium Channels/genetics ; Humans ; Hydrocortisone ; Hyperaldosteronism/complications ; Hyperaldosteronism/genetics ; Hyperaldosteronism/surgery ; Hypertension/complications ; Middle Aged ; Steroid 11-beta-Hydroxylase/genetics
    Chemical Substances G Protein-Coupled Inwardly-Rectifying Potassium Channels ; KCNJ5 protein, human ; Aldosterone (4964P6T9RB) ; Cytochrome P-450 CYP11B2 (EC 1.14.15.4) ; Steroid 11-beta-Hydroxylase (EC 1.14.15.4) ; Hydrocortisone (WI4X0X7BPJ)
    Language English
    Publishing date 2022-03-18
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2022.816754
    Database MEDical Literature Analysis and Retrieval System OnLINE

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