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  1. Article ; Online: Intra-Abdominal Adhesions and Peritoneal Dialysis: A Challenge, Not a Contraindication.

    Hsu, Caroline M / Varma, Manish / Weiner, Daniel E

    Clinical journal of the American Society of Nephrology : CJASN

    2024  Volume 19, Issue 4, Page(s) 412–414

    MeSH term(s) Humans ; Contraindications ; Peritoneal Dialysis/adverse effects
    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.0000000000000447
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Dialysate Sodium Lowering in Maintenance Hemodialysis A Randomized Clinical Trial.

    Miskulin, Dana C / Tighiouart, Hocine / Hsu, Caroline M / Weiner, Daniel E

    Clinical journal of the American Society of Nephrology : CJASN

    2024  

    Abstract: Introduction: Lowering dialysate sodium may improve volume and blood pressure control in maintenance hemodialysis patients.: Methods: We randomized 42 participants 2:1 to dialysate sodium 135 vs. 138 mEq/L for 6 months. This was followed by a 12 week ...

    Abstract Introduction: Lowering dialysate sodium may improve volume and blood pressure control in maintenance hemodialysis patients.
    Methods: We randomized 42 participants 2:1 to dialysate sodium 135 vs. 138 mEq/L for 6 months. This was followed by a 12 week extension in which sodium was increased to 140 mEq/L in low arm participants. The primary outcome was intradialytic hypotension (IDH). Secondary outcomes included dialysis disequilibrium symptoms, ER visits/hospitalizations, interdialytic weight gain, blood pressure (BP). Longitudinal changes across arms were analyzed using linear mixed regression.
    Results: Treatment to dialysate sodium 135 vs. 138 mEq/L was not associated with a difference in a change in the rate of IDH (mean change (95%CI) 2.8 (0.8,9.5) vs. 2.7 (1.1, 6.2) events per 100 treatments per month; ratio of slopes 0.96(0.26,3.61) or ER visits/hospitalizations (7.3 (2.3, 12.4) vs. 6.7 (2.9, 10.6) events per 100 patient months; difference 0.6(-6.9,5.8). Symptom score was unchanged in the 135 mEq/L arm (0.7 (-1.4,2.7) and decreased in the 138 mEq/l arm (5.0,8.5,2.0); difference 6.0 (2.1,9.8)). Interdialytic weight gain declined in the 135 mEq/L arm and was unchanged in the 138 mEq/L arm,(-0.3(-0.5,0.0) vs. 0.3 (0.0, 0.6) kg over 6 months; difference (-0.6 (-0.1,-1.0) kg). In the extension phase, raising dialysate sodium from 135 to 140 mEq/L was associated with an increase in interdialytic weight gain (0.2 (0.1, 0.3) kg), predialysis BP (7.0 (4.8, 9.2)/ 3.9 (2.6, 5.1) mm Hg) and a reduction in IDH [OR 0.66 (0.45, 0.97)].
    Conclusion: Use of a dialysate sodium of 135 as compared with 138 mEq/L was associated with a small reduction in interdialytic weight gain without impact on IDH or predialysis BP, but with an increase in symptoms. Raising dialysate sodium from 135 to 140mEq/L was associated with a reduction in IDH, a small increase in interdialytic weight gain and a marked increase in predialysis BP.
    Language English
    Publishing date 2024-02-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.0000000000000431
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: COVID-19 and Dialysis: What's Past Is Prologue.

    Reaves, Allison C / Weiner, Daniel E / Hsu, Caroline M

    Kidney medicine

    2022  Volume 4, Issue 11, Page(s) 100555

    Language English
    Publishing date 2022-10-12
    Publishing country United States
    Document type Editorial ; Comment
    ISSN 2590-0595
    ISSN (online) 2590-0595
    DOI 10.1016/j.xkme.2022.100555
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: COVID-19 in dialysis patients: outlasting and outsmarting a pandemic.

    Hsu, Caroline M / Weiner, Daniel E

    Kidney international

    2020  Volume 98, Issue 6, Page(s) 1402–1404

    Abstract: Coronavirus disease 2019 (COVID-19) has affected the care and outcomes of patients treated with dialysis worldwide. In this issue of Kidney International, 3 reports highlight the disproportionately severe impact of COVID-19 on patients on dialysis, ... ...

    Abstract Coronavirus disease 2019 (COVID-19) has affected the care and outcomes of patients treated with dialysis worldwide. In this issue of Kidney International, 3 reports highlight the disproportionately severe impact of COVID-19 on patients on dialysis, noting its high prevalence, particularly among patients receiving in-center dialysis. This likely reflects patients' limited ability to physically distance as well as community exposures, including residence in areas with high rates of infection. Patients on dialysis are at extremely high risk should they develop COVID-19, with short-term mortality of 20% or higher. Accordingly, it is imperative that the kidney community intervenes to reduce the threat of COVID-19 in this vulnerable population by focusing on modifiable factors, including universal masking of patients and staff and enhanced screening, including testing for COVID-19 in the patients who are asymptomatic during times of high local prevalence.
    MeSH term(s) COVID-19/complications ; Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/therapy ; Renal Dialysis
    Keywords covid19
    Language English
    Publishing date 2020-10-13
    Publishing country United States
    Document type Introductory Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2020.10.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Oral Agents and SARS-CoV-2 Vaccine Effectiveness against Severe COVID-19 Omicron Events in Patients Requiring Maintenance Dialysis.

    Manley, Harold J / Li, Nien Chen / Hsu, Caroline M / Weiner, Daniel E / Miskulin, Dana / Harford, Antonia M / Johnson, Doug / Lacson, Eduardo

    Kidney360

    2024  Volume 5, Issue 3, Page(s) 445–450

    MeSH term(s) Humans ; COVID-19 Vaccines ; COVID-19/prevention & control ; SARS-CoV-2 ; Vaccine Efficacy ; Renal Dialysis ; Administration, Oral
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article
    ISSN 2641-7650
    ISSN (online) 2641-7650
    DOI 10.34067/KID.0000000000000373
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: In Reply to "Using Immunoglobulin G Spike Antibodies as a Surrogate Marker for Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Additional Considerations".

    Hsu, Caroline M / Weiner, Daniel E / Manley, Harold J / Johnson, Doug / Lacson, Eduardo K

    Kidney medicine

    2023  Volume 6, Issue 1, Page(s) 100781

    Language English
    Publishing date 2023-12-14
    Publishing country United States
    Document type Journal Article
    ISSN 2590-0595
    ISSN (online) 2590-0595
    DOI 10.1016/j.xkme.2023.100781
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: COVID-19 in Dialysis Patients: Outlasting and Outsmarting a Pandemic

    Hsu, Caroline M / Weiner, Daniel E

    Kidney int

    Abstract: COVID-19 has affected dialysis patients and dialysis patient care worldwide. In this issue of Kidney International, three reports highlight the disproportionately severe impact of COVID-19 on dialysis patients, noting its high prevalence, particularly ... ...

    Abstract COVID-19 has affected dialysis patients and dialysis patient care worldwide. In this issue of Kidney International, three reports highlight the disproportionately severe impact of COVID-19 on dialysis patients, noting its high prevalence, particularly among in-center dialysis patients. This likely reflects patients' limited ability to physically distance as well as community exposures, including residence in areas with high rates of infection. Dialysis patients are at extremely high risk should they develop COVID-19, with short-term mortality of 20% or higher. Accordingly, it is imperative that the kidney community intervene to reduce the threat of COVID-19 in the vulnerable population by focusing on modifiable factors, including universal masking of patients and staff and enhanced screening, including testing asymptomatic patients for COVID-19 in times of high local prevalence.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #856949
    Database COVID19

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  8. Article ; Online: COVID-19 in dialysis patients

    Hsu, Caroline M. / Weiner, Daniel E.

    Kidney International ; ISSN 0085-2538

    outlasting and outsmarting a pandemic

    2020  

    Keywords Nephrology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.kint.2020.10.005
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Epidemiology and Outcomes of COVID-19 in Home Dialysis Patients Compared with In-Center Dialysis Patients.

    Hsu, Caroline M / Weiner, Daniel E / Aweh, Gideon / Salenger, Page / Johnson, Doug S / Lacson, Eduardo

    Journal of the American Society of Nephrology : JASN

    2021  Volume 32, Issue 7, Page(s) 1569–1573

    Language English
    Publishing date 2021-06-09
    Publishing country United States
    Document type Letter
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.2020111653
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Outcomes of palliative care consultation in patients with ESRD who received cardiopulmonary resuscitation.

    Hsu, Caroline M / Murad, Haris / Neuendorf, Kathleen / Gao, Tianming / Schold, Jesse D / Saeed, Fahad

    Clinical nephrology

    2021  Volume 96, Issue 1, Page(s) 22–28

    Abstract: Background: The majority of dialysis patients receive aggressive burdensome treatment near the end of life. Currently, we lack interventions to improve end-of-life care (EoLC) for these patients. We examined the association of palliative care ... ...

    Abstract Background: The majority of dialysis patients receive aggressive burdensome treatment near the end of life. Currently, we lack interventions to improve end-of-life care (EoLC) for these patients. We examined the association of palliative care consultation with improving EoLC for critically ill patients with end-stage renal disease (ESRD) who received cardiopulmonary resuscitation (CPR).
    Materials and methods: In this retrospective study, we included patients with ESRD admitted to a large academic center who received CPR either prior to or during their hospital stay. Over 8 years, 17 out of 403 patients received palliative care consultation during their hospital stay; consultations were not standardized in their content. Main outcomes of interest to operationalize better EoLC were: (1) change in code status from full code to do not resuscitate (DNR) and (2) withdrawal from intensive care.
    Results: Of the patients studied, 60.5% were African-American and 43.2% were female. Demographic differences between those with palliative care consultation and those with usual care were not statistically significant. Palliative care consultation was associated with higher odds of change in code status to DNR (odds ratio 8.10, 95% confidence interval 2.19 - 29.94) and withdrawal from intensive care (odds ratio 8.82, 95% confidence interval 2.69 - 28.91) in patients with ESRD who had received CPR. Palliative care consultation was not associated with any change in in-hospital mortality.
    Conclusion: Palliative care consultation needs to be considered for hospitalized ESRD patients with limited expected prognoses as it may reduce aggressive and burdensome therapies at the end of life. Furthermore, primary palliative care skills such as communication and decision-making should be taught to nephrologists to improve EoLC for dialysis patients.
    MeSH term(s) Cardiopulmonary Resuscitation ; Humans ; Kidney Failure, Chronic/epidemiology ; Kidney Failure, Chronic/therapy ; Palliative Care ; Referral and Consultation/statistics & numerical data ; Renal Dialysis ; Retrospective Studies ; Terminal Care
    Language English
    Publishing date 2021-01-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 185101-9
    ISSN 0301-0430
    ISSN 0301-0430
    DOI 10.5414/CN110096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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