LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 7 of total 7

Search options

  1. Article ; Online: Dual biomarkers-activatable hollow MnO

    Ning, Juan / Hu, Guizhen / Wu, Tian / Zhao, Yijun / Nie, Yamin / Zhou, Yanmei

    Analytica chimica acta

    2024  Volume 1303, Page(s) 342521

    Abstract: Background: Theranostic nanoplatforms with integrated diagnostic imaging and multiple therapeutic functions play a vital role in precise diagnosis and efficient treatment for breast cancer, but unfortunately, these nanoplatforms are usually stuck in ... ...

    Abstract Background: Theranostic nanoplatforms with integrated diagnostic imaging and multiple therapeutic functions play a vital role in precise diagnosis and efficient treatment for breast cancer, but unfortunately, these nanoplatforms are usually stuck in single-site imaging and single mode of treatment, causing unsatisfactory diagnostic and therapeutic efficiency. Herein, a dual biomarkers-activatable facile hollow mesoporous MnO
    Results: The DHMM acted as an integrated diagnostic and therapeutic nanoplatform that realizes multi-site fluorescence imaging-guided high-efficient photothermal/chemodynamic/gene synergistic therapy (PTT/CDT/GT) for breast cancer. The H-MnO
    Significance: This dual biomarker-activatable multiple therapeutic nanoplatform was realized multi-site fluorescence imaging-guided PTT/CDT/GT combination therapy for breast cancer with higher specificity and efficiency, which provides a promising theranostic nanoplatform for the precision and efficiency of breast cancer treatment.
    MeSH term(s) Precision Medicine ; DNA, Catalytic ; Manganese Compounds ; Oxides ; Optical Imaging ; Biomarkers ; Neoplasms ; Carbocyanines
    Chemical Substances cyanine dye 5 ; DNA, Catalytic ; Manganese Compounds ; Oxides ; Biomarkers ; Carbocyanines
    Language English
    Publishing date 2024-03-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1483436-4
    ISSN 1873-4324 ; 0003-2670
    ISSN (online) 1873-4324
    ISSN 0003-2670
    DOI 10.1016/j.aca.2024.342521
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: A photoluminescence strategy for detection nanoplastics in water and biological imaging in cells and plants.

    Wu, Tian / Hu, Guizhen / Ning, Juan / Yang, Jialu / Zhou, Yanmei

    Journal of hazardous materials

    2023  Volume 461, Page(s) 132695

    Abstract: Nanoplastics exposure poses a significant threat to the environment and human health, and accurate measurement of nanoparticles in aqueous solutions remains challenging. In this work, we synthesized the cationic fluorescent probe 4-[1-Cyano- 2-[4-( ... ...

    Abstract Nanoplastics exposure poses a significant threat to the environment and human health, and accurate measurement of nanoparticles in aqueous solutions remains challenging. In this work, we synthesized the cationic fluorescent probe 4-[1-Cyano- 2-[4-(Diethylamino)-2-hydroxyphenyl]ethenyl]-1-ethylpyridinium (PCP) through a straightforward procedure for the rapid and accurate detection and labeling of nanoplastics in aqueous solutions. PCP binds to nanoplastics through electrostatic and hydrophobic interactions with restricted intramolecular rotation and exhibits enhanced fluorescence emission. Using carboxylation-modified polystyrene nanoplastics as a model, PCP could accurately detect concentrations as low as 0.525 mg∙L
    MeSH term(s) Humans ; Microplastics ; Water ; Reproducibility of Results ; Polystyrenes/chemistry ; Nanoparticles/chemistry ; Water Pollutants, Chemical/analysis
    Chemical Substances Microplastics ; Water (059QF0KO0R) ; Polystyrenes ; Water Pollutants, Chemical
    Language English
    Publishing date 2023-10-02
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2023.132695
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: A DNA-Au nanomachine activated by dual types of biomarkers for multi-site imaging and gene silencing.

    Zhou, Yanmei / Li, Zhaoge / Wu, Tian / Ning, Juan / Hu, Guizhen / Nie, Yamin

    Chemical communications (Cambridge, England)

    2022  Volume 58, Issue 94, Page(s) 13107–13110

    Abstract: A programmed DNA-Au nanomachine has been constructed to ... ...

    Abstract A programmed DNA-Au nanomachine has been constructed to achieve
    MeSH term(s) Humans ; DNA/genetics ; MCF-7 Cells ; Diagnostic Imaging ; Gene Silencing ; Biomarkers ; MicroRNAs/genetics ; Biosensing Techniques/methods
    Chemical Substances DNA (9007-49-2) ; Biomarkers ; MicroRNAs
    Language English
    Publishing date 2022-11-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d2cc05017j
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Prepared carbon dots from wheat straw for detection of Cu

    Shi, Jiahui / Zhou, Yunhao / Ning, Juan / Hu, Guizhen / Zhang, Qingyou / Hou, Yabin / Zhou, Yanmei

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2022  Volume 281, Page(s) 121597

    Abstract: The green synthesis of fluorescent carbon dots from biomass is critical for their sustainable application. Herein, using wheat straw as a single precursor, carbon dots (CDs) were prepared through a one-step carbonization process, and the obtained CDs ... ...

    Abstract The green synthesis of fluorescent carbon dots from biomass is critical for their sustainable application. Herein, using wheat straw as a single precursor, carbon dots (CDs) were prepared through a one-step carbonization process, and the obtained CDs have intense blue luminescence and excitation-independent photoluminescent behavior. The solution of CDs shows good biocompatibility, and low cytotoxicity successfully used as hopeful bioimaging and biosensing probe for Cu
    MeSH term(s) Animals ; Boron ; Carbon ; Quantum Dots ; Temperature ; Triticum ; Zebrafish
    Chemical Substances Carbon (7440-44-0) ; Boron (N9E3X5056Q)
    Language English
    Publishing date 2022-07-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2022.121597
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 51/98: Show issues
    Z 1611 a: Show issues
    924/340: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: Construction of an in vivo NIR fluorescent probe for revealing the correlation between inflammation and mitochondrial hydrogen sulfide and viscosity.

    Cui, Yali / Hu, Guizhen / Wu, Tian / Yang, Jialu / Nie, Yamin / Zhou, Yanmei

    Bioorganic chemistry

    2022  Volume 129, Page(s) 106107

    Abstract: As an indispensable part of immune response, inflammation plays a critical role in the occurring and advancing of many diseases. It is reported that the emergence of inflammation can be indicated by the change of intracellular viscosity and ... ...

    Abstract As an indispensable part of immune response, inflammation plays a critical role in the occurring and advancing of many diseases. It is reported that the emergence of inflammation can be indicated by the change of intracellular viscosity and overexpression of the hydrogen sulfide (H<sub>2</sub>S) in mitochondria. So far, elucidating the relationship between inflammation and the above parameters remains a challenge due to the lack of validated analytical tools. Herein, a novel dual-function NIR fluorescent probe CMQT with excellent biological compatibility and mitochondrial targeting ability is designed and synthesized by using 7-diethylaminocoumarin and 4-ethylphenolate quinoline acetate through twistable vinyl bonds. With the functional probe, enhanced fluorescent signals at 570 nm and 721 nm are produced in the presence of H<sub>2</sub>S and changes of viscosity. The CMQT can be applied in living cells and zebrafish, which reveals the increases of mitochondrial H<sub>2</sub>S and viscosity generated by inflammatory response through dual-channel fluorescence imaging mode. The in vivo dual-functional probe serves as an efficient tool for imaging analysis of H<sub>2</sub>S and viscosity, and has profound implications for the early diagnosis of inflammatory diseases.
    MeSH term(s) Animals ; Humans ; Fluorescent Dyes/chemistry ; Hydrogen Sulfide/analysis ; Viscosity ; Zebrafish ; Optical Imaging/methods ; Mitochondria/chemistry ; Inflammation/diagnostic imaging ; HeLa Cells
    Chemical Substances Fluorescent Dyes ; Hydrogen Sulfide (YY9FVM7NSN)
    Language English
    Publishing date 2022-08-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 120080-x
    ISSN 1090-2120 ; 0045-2068
    ISSN (online) 1090-2120
    ISSN 0045-2068
    DOI 10.1016/j.bioorg.2022.106107
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4207: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: A Review of ApoE4 Interference Targeting Mitophagy Molecular Pathways for Alzheimer's Disease.

    Chen, Huiyi / Chen, Feng / Jiang, Ying / Zhang, Lu / Hu, Guizhen / Sun, Furong / Zhang, Miaoping / Ji, Yao / Chen, Yanting / Che, Gang / Zhou, Xu / Zhang, Yu

    Frontiers in aging neuroscience

    2022  Volume 14, Page(s) 881239

    Abstract: Alzheimer's disease (AD) is one of the major worldwide causes of dementia that is characterized by irreversible decline in learning, memory loss, and behavioral impairments. Mitophagy is selective autophagy through the clearance of aberrant mitochondria, ...

    Abstract Alzheimer's disease (AD) is one of the major worldwide causes of dementia that is characterized by irreversible decline in learning, memory loss, and behavioral impairments. Mitophagy is selective autophagy through the clearance of aberrant mitochondria, specifically for degradation to maintain energy generation and neuronal and synaptic function in the brain. Accumulating evidence shows that defective mitophagy is believed to be as one of the early and prominent features in AD pathogenesis and has drawn attention in the recent few years.
    Language English
    Publishing date 2022-05-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2558898-9
    ISSN 1663-4365
    ISSN 1663-4365
    DOI 10.3389/fnagi.2022.881239
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: UB2/UB3/TSH4-anchored transcriptional networks regulate early maize inflorescence development in response to simulated shade.

    Kong, Dexin / Li, Changyu / Xue, Weicong / Wei, Hongbin / Ding, Hui / Hu, Guizhen / Zhang, Xiaoming / Zhang, Guisen / Zou, Ting / Xian, Yuting / Wang, Baobao / Zhao, Yongping / Liu, Yuting / Xie, Yurong / Xu, Miaoyun / Wu, Hong / Liu, Qing / Wang, Haiyang

    The Plant cell

    2022  Volume 35, Issue 2, Page(s) 717–737

    Abstract: Increasing planting density has been adopted as an effective means to increase maize (Zea mays) yield. Competition for light from neighbors can trigger plant shade avoidance syndrome, which includes accelerated flowering. However, the regulatory networks ...

    Abstract Increasing planting density has been adopted as an effective means to increase maize (Zea mays) yield. Competition for light from neighbors can trigger plant shade avoidance syndrome, which includes accelerated flowering. However, the regulatory networks of maize inflorescence development in response to high-density planting remain poorly understood. In this study, we showed that shade-mimicking treatments cause precocious development of the tassels and ears. Comparative transcriptome profiling analyses revealed the enrichment of phytohormone-related genes and transcriptional regulators among the genes co-regulated by developmental progression and simulated shade. Network analysis showed that three homologous Squamosa promoter binding protein (SBP)-like (SPL) transcription factors, Unbranched2 (UB2), Unbranched3 (UB3), and Tasselsheath4 (TSH4), individually exhibited connectivity to over 2,400 genes across the V3-to-V9 stages of tassel development. In addition, we showed that the ub2 ub3 double mutant and tsh4 single mutant were almost insensitive to simulated shade treatments. Moreover, we demonstrated that UB2/UB3/TSH4 could directly regulate the expression of Barren inflorescence2 (BIF2) and Zea mays teosinte branched1/cycloidea/proliferating cell factor30 (ZmTCP30). Furthermore, we functionally verified a role of ZmTCP30 in regulating tassel branching and ear development. Our results reveal a UB2/UB3/TSH4-anchored transcriptional regulatory network of maize inflorescence development and provide valuable targets for breeding shade-tolerant maize cultivars.
    MeSH term(s) Inflorescence/genetics ; Inflorescence/metabolism ; Zea mays/metabolism ; Gene Regulatory Networks ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism
    Chemical Substances Plant Proteins ; Transcription Factors
    Language English
    Publishing date 2022-12-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 623171-8
    ISSN 1532-298X ; 1040-4651
    ISSN (online) 1532-298X
    ISSN 1040-4651
    DOI 10.1093/plcell/koac352
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 4952: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top