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Article ; Online: Deep Learning-Based Technique for Remote Sensing Image Enhancement Using Multiscale Feature Fusion.

Zhao, Ming / Yang, Rui / Hu, Min / Liu, Botao

2024 Volume 24, Issue 2

Abstract: The present study proposes a novel deep-learning model for remote sensing image enhancement. It maintains image details while enhancing brightness in the feature extraction module. An improved hierarchical model named Global Spatial Attention Network ( ... ...

Abstract	The present study proposes a novel deep-learning model for remote sensing image enhancement. It maintains image details while enhancing brightness in the feature extraction module. An improved hierarchical model named Global Spatial Attention Network (GSA-Net), based on U-Net for image enhancement, is proposed to improve the model's performance. To circumvent the issue of insufficient sample data, gamma correction is applied to create low-light images, which are then used as training examples. A loss function is constructed using the Structural Similarity (
Language	English
Publishing date	2024-01-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s24020673
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: [Nitrate Pollution Characteristics and Its Quantitative Source Identification of Major River Systems in China].

Wei, Ying-Huai / Hu, Min-Peng / Chen, Ding-Jiang

Huan jing ke xue= Huanjing kexue

2024 Volume 45, Issue 2, Page(s) 755–767

Abstract: Accurate source identification/apportionment is essential for optimizing water ... ...

Abstract	Accurate source identification/apportionment is essential for optimizing water NO
Language	Chinese
Publishing date	2024-03-12
Publishing country	China
Document type	English Abstract ; Journal Article
ISSN	0250-3301
ISSN	0250-3301
DOI	10.13227/j.hjkx.202304069
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Article ; Online: Mechanism analysis of Buyang Huanwu decoction in treating atherosclerosis based on network pharmacology and in vitro experiments.

Wang, Jing / Li, Jiajun / Hu, Min

Chemical biology & drug design

2024 Volume 103, Issue 1, Page(s) e14447

Abstract: Atherosclerosis (AS) is one of the main risk factors of ischemic cardiovascular and cerebrovascular diseases. Buyang Huanwu decoction (BYHWT) is a classic Chinese medicine prescription that is used for treating AS. However, the underlying pharmacological ...

Abstract	Atherosclerosis (AS) is one of the main risk factors of ischemic cardiovascular and cerebrovascular diseases. Buyang Huanwu decoction (BYHWT) is a classic Chinese medicine prescription that is used for treating AS. However, the underlying pharmacological mechanism remains unclear. This study aims to clarify the molecular mechanism of BYHWT in treatment of AS through network pharmacology and in vitro experiments. Molecular structure information and targets of core components of BYHWT were obtained from PubChem and UniProtKB databases. Genes involved in AS were obtained from DisGeNet, GeneCards and OMIM databases. The core targets of BYHWT in AS treatment were identified by protein-protein interaction (PPI) network analysis with STRING platform, and analyzed by gene ontology (GO) analysis and the Kyoto Encyclopedia of Genes and Genomics (KEGG) pathway enrichment analysis. Molecular docking was used to verify the binding affinity between the core targets and the bioactive ingredients. HUVEC viability, inflammatory response and mRNA expression levels of core target genes were evaluated by cell counting kit 8 assay, enzyme-linked immunosorbent assay (ELISA) and qRT-PCR. A total of 60 candidate compounds and 325 predicted target genes were screened. PPI network analysis suggested that TP53, SRC, STAT3, and AKT1 may be the core targets. BYHWT in AS treatment was associated with 46 signaling pathways. GA120, baicalein, and 3,9-di-o-methylnissolin had good binding affinity with core target proteins. Baicalein treatment could significantly promoted the viability and repress the inflammatory response of HUVEC cells stimulated by ox-LDL. In addition, Baicalein can regulate the expression of core targets including AKT1, MAPK1, PIK3CA, JUN, TP53, SRC, EGFR, and ESR1. In conclusion, BYHWT and its main bioactive component baicalein, inhibit inflammatory response and modulate multiple downstream genes of endothelial cells, and show good potential to block the progression of AS and cardiovascular/cerebrovascular diseases.
MeSH term(s)	Humans ; Network Pharmacology ; Endothelial Cells ; Molecular Docking Simulation ; Atherosclerosis/drug therapy ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Cardiovascular Diseases ; Cerebrovascular Disorders
Chemical Substances	buyang huanwu ; Drugs, Chinese Herbal
Language	English
Publishing date	2024-01-16
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2216600-2
ISSN	1747-0285 ; 1747-0277
ISSN (online)	1747-0285
ISSN	1747-0277
DOI	10.1111/cbdd.14447
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Trends in socioeconomic inequalities in breast cancer mortality in Canada: 1992-2019.

Nasiri, Nazanin / Hu, Min / Hajizadeh, Mohammad

Breast cancer research and treatment

2024

Abstract: Purpose: Breast cancer is the second leading cause of death from cancer among Canadian females. This study aimed to quantify and assess trends in education and income inequalities in the mortality rate of breast cancer in Canada from 1992 to 2019.: ... ...

Abstract	Purpose: Breast cancer is the second leading cause of death from cancer among Canadian females. This study aimed to quantify and assess trends in education and income inequalities in the mortality rate of breast cancer in Canada from 1992 to 2019. Methods: We constructed a census division-level dataset pooled from the Canadian Vital Death Statistics Database (CVSD), the Canadian Census of the Population (CCP), and the National Household Survey (NHS) to examine trends in education and income inequalities in the mortality rate of breast cancer in Canada over the study period. The age-standardized Concentration index (C) was used to quantify income and education inequalities in breast cancer mortality over time. Results: The national crude mortality rate of breast cancer has decreased in Canada from 1992 to 2019, with Alberta, British Columbia, Manitoba, Ontario, Prince Edward Island, and Quebec having the greatest decreases in mortality rate. The age-standardized C for education and income inequalities were always negative for all the study years, meaning that the mortality rate of breast cancer was higher among less-educated and poorer females. Moreover, the results indicate a growing trend in the concentration of breast cancer mortality among females with lower income and education from 1992 to 2019. Conclusion: The increasing concentration of breast cancer mortality among low socioeconomic status females remains a challenge in Canada. Continuous efforts are needed within Canadian healthcare system to improve the prevention and treatment of breast cancer for this population.
Language	English
Publishing date	2024-03-19
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	604563-7
ISSN	1573-7217 ; 0167-6806
ISSN (online)	1573-7217
ISSN	0167-6806
DOI	10.1007/s10549-024-07277-y
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Zs.A 1655: Show issues

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Article ; Online: Rapid Continuous 3D Printing via Orthogonal Dual-Color Photoinitiation and Photoinhibition.

Hu, Min / Cheng, Haobo / Feng, Yunpeng

3D printing and additive manufacturing

2024 Volume 11, Issue 2, Page(s) 476–484

Abstract: Stereolithographic additive manufacturing technology has developed from point-by-point scanning exposure to layer-by-layer masking curing and even volumetric printing. Rapid prototyping is one of the important goals pursued by researchers. A continuous ... ...

Abstract	Stereolithographic additive manufacturing technology has developed from point-by-point scanning exposure to layer-by-layer masking curing and even volumetric printing. Rapid prototyping is one of the important goals pursued by researchers. A continuous three-dimensional (3D) printing system based on the dual-color photoinitiation and photoinhibition is proposed with the aim of further improving printing speed. The process of continuous 3D printing is realized through the anti-polymerization layer between the cured part and the window generated by the ultraviolet (UV) light sheet (355 nm), and dynamic masking with the blue light (470 nm). The volume of the anti-polymerization layer can be adjusted by the intensity ratio of the incident lights (
Language	English
Publishing date	2024-04-16
Publishing country	United States
Document type	Journal Article
ISSN	2329-7670
ISSN (online)	2329-7670
DOI	10.1089/3dp.2022.0278
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Article ; Online: Intermittent horizontal mattress suture technique in aortic root anastomosis for acute type-A aortic dissection surgery.

Hu, Min / Wang, Jing / Zhou, Yongzhi / Wei, Xiang

Asian journal of surgery

2024 Volume 47, Issue 5, Page(s) 2281–2283

MeSH term(s)	Humans ; Aortic Dissection/surgery ; Suture Techniques ; Anastomosis, Surgical/methods ; Aorta/surgery ; Male ; Acute Disease ; Vascular Surgical Procedures/methods ; Treatment Outcome ; Middle Aged ; Female ; Aortic Aneurysm/surgery
Language	English
Publishing date	2024-02-19
Publishing country	Netherlands
Document type	Letter
ZDB-ID	1068461-x
ISSN	0219-3108 ; 1015-9584
ISSN (online)	0219-3108
ISSN	1015-9584
DOI	10.1016/j.asjsur.2024.01.153
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Zs.B 2831: Show issues

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Article ; Online: Controversy and progress of peritoneal drainage after hepatectomy

LI Ning / HU Min / YAN Jun

Zhongguo linchuang yanjiu, Vol 36, Iss 9, Pp 1281-

2023 Volume 1285

Abstract: After resection, abdominal drainage is generally used to drain the exudate at the surgical site timely and monitor possible postoperative complications. With the development of the concept of enhanced recovery after surgery, there is a great controversy ... ...

Abstract	After resection, abdominal drainage is generally used to drain the exudate at the surgical site timely and monitor possible postoperative complications. With the development of the concept of enhanced recovery after surgery, there is a great controversy about whether to place drainage tube and its retention time after hepatectomy. Based on the research progress at home and abroad, this article reviews whether to place drainage tubes after hepatectomy, commonly abdominal drainage devices in clinical practice, the timing and indications of drainage tube removal, possible complications and preventive measures caused by indwelling drainage tubes, and the improvement effect of intelligent drainage devices on drainage management. The above issues are reconsidered in order to improve the application and management of abdominal drainage after hepatectomy at the level of precision medicine.
Keywords	hepatectomy ; abdominal drainage ; drainage management ; intelligent drainage device ; bile leakage ; retrograde infection ; abdominal effusion ; Medicine ; R
Subject code	720
Language	Chinese
Publishing date	2023-09-01T00:00:00Z
Publisher	The Editorial Department of Chinese Journal of Clinical Research
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Mind the Gap: What Factors Determine the Worse Health Status of Indigenous Women Relative to Men Living Off-Reserve in Canada?

Hu, Min / Hajizadeh, Mohammad

Journal of racial and ethnic health disparities

2022 Volume 10, Issue 3, Page(s) 1138–1164

Abstract: Background: Indigenous populations have the poorest health outcomes in Canada. In addition, some studies report notable gender health gaps among Indigenous populations of Canada, with greater disadvantages for Indigenous women. To date, the driving ... ...

Abstract	Background: Indigenous populations have the poorest health outcomes in Canada. In addition, some studies report notable gender health gaps among Indigenous populations of Canada, with greater disadvantages for Indigenous women. To date, the driving factors behind the health gaps between Indigenous women and men are poorly understood. Method: Using the four available Aboriginal People Surveys (APS) (2001, 2006, 2012, and 2017), we measure gender gaps in good general health (GGH) (i.e. good/very good/excellent self-rated health) among Indigenous adults (age 18 and above) living off-reserve in Canada. We apply the Oaxaca-Blinder (OB) decomposition method to identify the relative contribution of health endowments and the return to these endowments to the gender health gaps among Indigenous peoples. Results: Indigenous men are found to have a higher rate of GGH than their female counterparts. The gender health gap among Indigenous people has somewhat widened over the period 2001 to 2017. The widening of the gender health gap was observed in all four Indigenous identity groups, viz. registered First Nations, non-registered First Nations, Métis, and Inuit. The OB decomposition suggests that differences in endowments such as employment status and income between men and women explain between 30 to 60% of the gender health gap among Indigenous populations in Canada over the study period. Conclusion: The social determinants of health appear to be the main factor explaining the gender health gap within the Indigenous peoples living in Canada. Policies improving employment opportunities and income among Indigenous women may potentially reduce the gender health gap within Indigenous population in Canada.
MeSH term(s)	Adolescent ; Adult ; Female ; Humans ; Male ; Canada/epidemiology ; Health Status ; Indians, North American ; Indigenous Canadians ; Sex Factors ; Socioeconomic Factors ; Surveys and Questionnaires ; Social Determinants of Health/statistics & numerical data
Language	English
Publishing date	2022-05-05
Publishing country	Switzerland
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2760524-3
ISSN	2196-8837 ; 2197-3792
ISSN (online)	2196-8837
ISSN	2197-3792
DOI	10.1007/s40615-022-01301-x
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Article ; Online: Transformation to ischaemia tolerance of frog brain function corresponds to dynamic changes in mRNA co-expression across metabolic pathways.

Hu, Min / Santin, Joseph M

Proceedings. Biological sciences

2022 Volume 289, Issue 1979, Page(s) 20221131

Abstract: Neural activity is costly and requires continuous ATP from aerobic metabolism. Brainstem motor function of American bullfrogs normally collapses after minutes of ischaemia, but following hibernation, it becomes ischaemia-tolerant, generating output for ... ...

Abstract	Neural activity is costly and requires continuous ATP from aerobic metabolism. Brainstem motor function of American bullfrogs normally collapses after minutes of ischaemia, but following hibernation, it becomes ischaemia-tolerant, generating output for up to 2 h without oxygen or glucose delivery. Transforming the brainstem to function during ischaemia involves a switch to anaerobic glycolysis and brain glycogen. We hypothesized that improving neural performance during ischaemia involves a transcriptional program for glycogen and glucose metabolism. Here we measured mRNA copy number of genes along the path from glycogen metabolism to lactate production using real-time quantitative PCR. The expression of individual genes did not reflect enhanced glucose metabolism. However, the number of co-expressed gene pairs increased early into hibernation, and by the end, most genes involved in glycogen metabolism, glucose transport and glycolysis exhibited striking linear co-expression. By contrast, co-expression of genes in the Krebs cycle and electron transport chain decreased throughout hibernation. Our results uncover reorganization of the metabolic transcriptional network associated with a shift to ischaemia tolerance in brain function. We conclude that modifying gene co-expression may be a critical step in synchronizing storage and use of glucose to achieve ischaemia tolerance in active neural circuits.
MeSH term(s)	Brain/metabolism ; Glucose/metabolism ; Glycogen/metabolism ; Glycolysis ; Humans ; Ischemia/metabolism ; RNA, Messenger/metabolism
Chemical Substances	RNA, Messenger ; Glycogen (9005-79-2) ; Glucose (IY9XDZ35W2)
Language	English
Publishing date	2022-07-27
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural
ZDB-ID	209242-6
ISSN	1471-2954 ; 0080-4649 ; 0962-8452 ; 0950-1193
ISSN (online)	1471-2954
ISSN	0080-4649 ; 0962-8452 ; 0950-1193
DOI	10.1098/rspb.2022.1131
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 1364: Show issues

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Article ; Online: The regulatory role of autophagy between TAMs and tumor cells.

Hu, Min / Fan, Jiao-Xiu / He, Zi-Yue / Zeng, Jun

Cell biochemistry and function

2024 Volume 42, Issue 2, Page(s) e3984

Abstract: Cancer has become a global public health problem and its harmful effects have received widespread attention. Conventional treatments such as surgical resection, radiotherapy and other techniques are applicable to clinical practice, but new drugs are ... ...

Abstract	Cancer has become a global public health problem and its harmful effects have received widespread attention. Conventional treatments such as surgical resection, radiotherapy and other techniques are applicable to clinical practice, but new drugs are constantly being developed and other therapeutic approaches, such as immunotherapy are being applied. In addition to studying the effects on individual tumor cells, it is important to explore the role of tumor microenvironment on tumor cell development since tumor cells do not exist alone but in the tumor microenvironment. In the tumor microenvironment, tumor cells are interconnected with other stromal cells and influence each other, among which tumor-associated macrophages (TAMs) are the most numerous immune cells. At the same time, it was found that cancer cells have different levels of autophagy from normal cells. In cancer therapy, the occurrence of autophagy plays an important role in promoting tumor cell death or inhibiting tumor cell death, and is closely related to the environment. Therefore, elucidating the regulatory role of autophagy between TAMs and tumor cells may be an important breakthrough, providing new perspectives for further research on antitumor immune mechanisms and improving the efficacy of cancer immunotherapy.
MeSH term(s)	Humans ; Tumor-Associated Macrophages/pathology ; Macrophages/metabolism ; Neoplasms/pathology ; Cell Differentiation ; Immunotherapy/methods ; Autophagy ; Tumor Microenvironment
Language	English
Publishing date	2024-03-17
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	283643-9
ISSN	1099-0844 ; 0263-6484
ISSN (online)	1099-0844
ISSN	0263-6484
DOI	10.1002/cbf.3984
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 1994: Show issues

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