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Article ; Online: Evaluation of root position during orthodontic treatment via multiple intraoral scans with automated registration technology.

Hu, Xueqin / Zhao, Yue / Yang, Chongshi

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics

2023 Volume 164, Issue 2, Page(s) 285–292

Abstract: Introduction: This study aimed to introduce a method for dynamically monitoring root position with intraoral scans using automated crown registration and root segmentation with artificial intelligence technology and to evaluate its accuracy using a ... ...

Abstract	Introduction: This study aimed to introduce a method for dynamically monitoring root position with intraoral scans using automated crown registration and root segmentation with artificial intelligence technology and to evaluate its accuracy using a novel semiautomatic root apical distance measurement procedure. Methods: The sample consisted of 412 teeth from 16 patients whose intraoral scans and cone-beam computed tomography (CBCT) were obtained before and after treatment. Crowns from intraoral scans and roots segmented from CBCT with artificial intelligence technology before treatment were registered, integrated, and divided into individual teeth. With an automated registration program, the virtual root was constructed by crown registration before and after treatment. The distance deviation of the root position at the apex between the virtual root and the actual root, which served as a control, was measured and decomposed into the distance deviation in the mesiodistal and buccolingual directions. Results: The shell deviation of crown registration between CBCT and oral scan before treatment was 0.19 ± 0.04 mm and 0.22 ± 0.04 mm in the maxilla and mandible, respectively. The apical root position distance deviations were 0.27 ± 0.12 mm in the maxilla and 0.31 ± 0.11 mm in the mandible. There was no significant difference between root position in mesiodistal and buccolingual directions. Conclusions: Applying automated crown registration and root segmentation with artificial intelligence technology in this study improved the accuracy and efficiency of monitoring root position. In addition, the innovative semiautomatic distance measurement procedure can more precisely distinguish the root position discrepancy.
MeSH term(s)	Humans ; Tooth Root/diagnostic imaging ; Artificial Intelligence ; Tooth ; Tooth Crown ; Crowns ; Cone-Beam Computed Tomography/methods
Language	English
Publishing date	2023-05-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	356699-7
ISSN	1097-6752 ; 0889-5406 ; 0002-9416
ISSN (online)	1097-6752
ISSN	0889-5406 ; 0002-9416
DOI	10.1016/j.ajodo.2023.04.012
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Ul III Zs.73: Show issues

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Article ; Online: Modification of the Loop Region Near the Substrate Tunnel to Alter the Hydrolytic Process of Dextranase.

Xia, Bingbing / Li, Zhiwei / Wei, Jinao / Hu, Ganpeng / Yang, Jingwen / Zhang, Hongbin / Hu, Xueqin

Journal of biotechnology

2024 Volume 381, Page(s) 57–66

Abstract: Dextranases are hydrolases that exclusively catalyze the disruption of α-1,6 glycosidic bonds. A series of variant enzymes were obtained by comparing the sequences of dextranases from different sources and introducing sequence substitutions. A ... ...

Abstract	Dextranases are hydrolases that exclusively catalyze the disruption of α-1,6 glycosidic bonds. A series of variant enzymes were obtained by comparing the sequences of dextranases from different sources and introducing sequence substitutions. A correlation was found between the number of amino acids in the 397-401 region and the hydrolytic process. When there were no more than 5 amino acids in the 397-401 region, the enzyme first hydrolyzed the dextran T70 to a low molecular weight dextran with a molecular weight of about 5000, then IMOs
MeSH term(s)	Hydrolysis ; Dextranase/genetics ; Dextranase/chemistry ; Dextrans/chemistry ; Molecular Weight ; Amino Acids
Chemical Substances	Dextranase (EC 3.2.1.11) ; Dextrans ; Amino Acids
Language	English
Publishing date	2024-01-06
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	843647-2
ISSN	1873-4863 ; 0168-1656 ; 1389-0352
ISSN (online)	1873-4863
ISSN	0168-1656 ; 1389-0352
DOI	10.1016/j.jbiotec.2024.01.003
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Zs.A 2299: Show issues

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Article ; Online: Vaccination against SARS-CoV-2 contributed to reducing the prevalence of depression in Chinese adults - A cross-sectional study.

Zhu, Yingying / Hu, Xueqin / Zhu, Kai / Zhou, Quan / Sun, Juan / Zhong, Zhenzhen / Zhang, Xiaobo

Journal of affective disorders

2024 Volume 349, Page(s) 407–413

Abstract: Background: SARS-CoV-2 vaccination has been reported to improve mental health. However, few relevant data were collected in China. The study aimed to evaluate the impact of SARS-CoV-2 vaccination on the risk of depression in China and risk factors ... ...

Abstract	Background: SARS-CoV-2 vaccination has been reported to improve mental health. However, few relevant data were collected in China. The study aimed to evaluate the impact of SARS-CoV-2 vaccination on the risk of depression in China and risk factors contributing to depression. Methods: This is a cross-sectional study carried out from May 2020 to July 2021. Participants were widely recruited in China to participate in the survey using an online questionnaire including Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Athens Insomnia Scale-8.After exclusion of 105 ineligible questionnaires, 9452 participants were included in our final analysis. Chi-square test and Multivariable logistic regression analysis were used to analyze data. Results: Of the 9452 participants, 7207 were vaccinated. Our results showed that the prevalence of depression decreased significantly after vaccination (56.1 % for unvaccinated participants vs. 19.7 % for vaccinated participants). The prevalence of mild, moderate and severe depression was also significantly lower in the vaccinated participants than in the unvaccinated participants (14.8 % vs 29.0 %, 2.8 % vs 13.3 %, 2.0 % vs 13.8 %, respectively). Besides, among vaccinated participants, male and aged participants had a lower chance of developing depression (AOR = 1.34; AOR = 0.63; AOR = 0.5, respectively). In addition, although with vaccination, participants with anxiety and insomnia were more likely to suffer from depression (AOR = 29.2; AOR = 11.89). Limitations: The study was a cross-sectional survey. The numbers of participants differed much in the two groups. Conclusions: The present study confirmed that SARS-CoV-2 vaccination contributed to reducing the prevalence of depression in Chinese adults. Moreover, vaccinated men and older adult participants had less prevalence of depression.
MeSH term(s)	Humans ; Male ; Aged ; Cross-Sectional Studies ; SARS-CoV-2 ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines/therapeutic use ; Depression/epidemiology ; Prevalence ; Sleep Initiation and Maintenance Disorders ; Vaccination ; China/epidemiology
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2024-01-06
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	135449-8
ISSN	1573-2517 ; 0165-0327
ISSN (online)	1573-2517
ISSN	0165-0327
DOI	10.1016/j.jad.2024.01.035
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Zs.A 1485: Show issues

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Article: Bibliometric Analysis of Global Trends in Research on Seasonal Variations in Gut Microbiota from 2012 to 2022.

Zhai, Jiancheng / Sun, Xiao / Lu, Rui / Hu, Xueqin / Huang, Zhiqiang

Microorganisms

2023 Volume 11, Issue 8

Abstract: Seasons are the important influencing factor for gut microbiota, which in turn affects the ecology and evolution of the host. The seasonal variation in gut microbiota has increasingly attracted the attention of researchers and professionals worldwide. ... ...

Abstract	Seasons are the important influencing factor for gut microbiota, which in turn affects the ecology and evolution of the host. The seasonal variation in gut microbiota has increasingly attracted the attention of researchers and professionals worldwide. However, studies of seasonal variations in gut microbiota have not been systematically analyzed by bibliometrics or visual analysis. This study is based on 271 publications from 2012 to 2022 in the Web of Science Core Collection database (WOSCC) to analyze hot spots and trends in this field. The collaborations between different countries, institutions, authors, journals, and keywords were bibliometrically analyzed using Excel, CiteSpace (Version 6.2. R4), and VOSviewer (version 1.6.19) software. The number of publications has been increasing rapidly and shows a general upward trend. China and the Chinese Academy of Sciences are the country and institution contributing the most, respectively. The research hotspots and trends mainly include the diversity of gut microbiota communities in different seasons, the relationship between diet and gut microbiota in seasonal changes, and the relationship between gut microbiota and evolutionary adaptation in seasonal changes. This is the first bibliometric and visualization analysis of seasonal variations in gut microbiota, which may advance this field and lay the foundation for future research.
Language	English
Publishing date	2023-08-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms11082125
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Article: Case presentation of

Chen, Ming / Song, Xiangquan / Shi, Miao / Zhang, Miao / Hu, Xueqin

Heliyon

2023 Volume 9, Issue 9, Page(s) e20014

Abstract: Pneumonia caused ... ...

Abstract	Pneumonia caused by
Language	English
Publishing date	2023-09-12
Publishing country	England
Document type	Case Reports
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e20014
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Article ; Online: Diagnosis and Analysis of Clinical Characteristics of

Chen, Ming / Zhang, Miao / Shi, Miao / Hu, Xueqin

Vector borne and zoonotic diseases (Larchmont, N.Y.)

2022 Volume 22, Issue 10, Page(s) 499–504

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Animals ; Chlamydophila psittaci ; Retrospective Studies ; Moxifloxacin ; Psittacosis/diagnosis ; Psittacosis/drug therapy ; Psittacosis/veterinary ; Pneumonia/complications ; Pneumonia/drug therapy ; Pneumonia/veterinary ; Fever/veterinary ; Anti-Bacterial Agents/therapeutic use ; Amides ; Nucleic Acids
Chemical Substances	Moxifloxacin (U188XYD42P) ; Anti-Bacterial Agents ; Amides ; Nucleic Acids
Language	English
Publishing date	2022-10-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2047199-3
ISSN	1557-7759 ; 1530-3667
ISSN (online)	1557-7759
ISSN	1530-3667
DOI	10.1089/vbz.2022.0013
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Zs.A 6137: Show issues

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Article ; Online: Sliding ferroelectricity and the moiré effect in Janus bilayer MoSSe.

Lin, Liyan / Hu, Xueqin / Meng, Ruijie / Li, Xu / Guo, Yandong / Da, Haixia / Jiang, Yue / Wang, Dongdong / Yang, Yurong / Yan, Xiaohong

Nanoscale

2024 Volume 16, Issue 9, Page(s) 4841–4850

Abstract: Two-dimensional van der Waals layered materials have attracted extensive attention in the field of low-dimensional ferroelectricity, on account of their readily delaminated structure and high-density information storage advantages. Here, we report the ... ...

Abstract	Two-dimensional van der Waals layered materials have attracted extensive attention in the field of low-dimensional ferroelectricity, on account of their readily delaminated structure and high-density information storage advantages. Here, we report the sliding ferroelectricity and moiré effects on the ferroelectricity in Janus bilayer MoSSe based on first-principles calculations. We focus on the changes of in-plane and out-of-plane polarizations due to sliding, and the calculations demonstrate that the in-plane and out-of-plane polarizations can be switched simultaneously by sliding. In addition, in moiré-twisted bilayer MoSSe, the complex stacking pattern and significant interlayer distance suppress the interlayer charge transfer, and the ferroelectric polarization is effectively suppressed. The polarization in the large-angle twisted structure is small but its direction can be adjusted by changing the twist angle. Our results emphasize the importance of low-dimensional ferroelectrics in van der Waals structures and pave a way for the search of sliding ferroelectric materials, as well as enriching the research on the ferroelectricity of large-angle twisted structures.
Language	English
Publishing date	2024-02-29
Publishing country	England
Document type	Journal Article
ZDB-ID	2515664-0
ISSN	2040-3372 ; 2040-3364
ISSN (online)	2040-3372
ISSN	2040-3364
DOI	10.1039/d3nr05730e
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Article: Xp21 DNA microdeletion syndrome in a Chinese family: clinical features show retinitis pigmentosa and chronic granuloma.

Li, Mengyang / Hu, Xueqin / Wu, Xueli / Zhao, Na / Lian, Yuanyuan / Ma, Meijiao / Li, Huiping / Sheng, Xunlun

Frontiers in genetics

2024 Volume 14, Page(s) 1276227

Abstract: Xp21 DNA microdeletion syndrome is a very rare disease characterized by retinitis pigmentosa (RP), chronic granulomatous disease (CGD), and McLeod syndrome (MLS). Due to the complex and diverse clinical manifestations, early diagnosis remains a challenge ...

Abstract	Xp21 DNA microdeletion syndrome is a very rare disease characterized by retinitis pigmentosa (RP), chronic granulomatous disease (CGD), and McLeod syndrome (MLS). Due to the complex and diverse clinical manifestations, early diagnosis remains a challenge for many physicians. In this study, for the purpose of determining the pathogenic gene variants and definitive diagnosis in a patient medically backgrounded with RP and CGD from a normal Chinese family, whole-exome sequencing (WES) was performed in this proband and copy number variation (CNV) was further verified in other family members by qPCR. A genetic evaluation revealed that the short arm of the X chromosome in the proband had a deletion CNV Xp21.1p11.4 (37431123-38186681) of approximately 0.755 Mb in size, and contained three contiguous OMIM genes as X-linked Kx blood group antigen (
Language	English
Publishing date	2024-01-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606823-0
ISSN	1664-8021
ISSN	1664-8021
DOI	10.3389/fgene.2023.1276227
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Article ; Online: Biosynthesis, Characterization, and Bioactivity of L-Alanyl-L-tyrosine in Promoting Melanin Synthesis.

Fan, Yuna / Wei, Jinao / Li, Zhiwei / Yang, Jingwen / Hu, Xueqin / Zhang, Hongbin

Applied biochemistry and biotechnology

2023

Abstract: L-Alanyl-L-tyrosine (L-Ala-Tyr) is a dipeptide formed by the condensation of L-alanine methyl ester and L-tyrosine. After entering the body, it can be rapidly broken down to release tyrosine. In this study, L-Ala-Tyr was successfully prepared by using α- ... ...

Abstract	L-Alanyl-L-tyrosine (L-Ala-Tyr) is a dipeptide formed by the condensation of L-alanine methyl ester and L-tyrosine. After entering the body, it can be rapidly broken down to release tyrosine. In this study, L-Ala-Tyr was successfully prepared by using α-ester acyltransferase as biocatalyst and alanine methyl ester (L-Ala-OMe) and tyrosine (L-Tyr) as acyl donor and nucleophile, respectively. The dipeptide yield was increased from 15 to 50% by optimizing the conditions: boric acid-borax (0.2 mol/L), 30°C, pH 9.5, 2:1 acyl donor to nucleophile ratio, DES (ChCl/urea), and 15%(v/v) water content. The catalytic product is then isolated and purified. The structure of the product was identified by high-performance liquid chromatography, mass spectrometry, proton nuclear magnetic resonance, and carbon spectroscopy. Its biological activity was preliminarily determined by the B16-F10 mouse melanoma cell model. The results showed that the purity of L-Ala-Tyr prepared by the separation and purification method of this study was 96.8%, and the mass spectrometry and nuclear magnetic resonance spectroscopy showed that the structure of the peptide was consistent with the expected structure. In addition, the preliminary physiological activity identification results show that L-Ala-Tyr has no toxic effect on cells in the concentration range of 100-800 μmol·L
Language	English
Publishing date	2023-09-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	392344-7
ISSN	1559-0291 ; 0273-2289
ISSN (online)	1559-0291
ISSN	0273-2289
DOI	10.1007/s12010-023-04713-5
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Zs.A 3053: Show issues

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Article ; Online: Mechanism analysis of a novel natural cationic modified dextran flocculant and its application in the treatment of blue algal blooms.

Wang, Lei / Zhang, Xinyu / Zhang, Xin / Hu, Xueqin / Yang, Jingwen / Zhang, Hongbin

International journal of biological macromolecules

2023 Volume 254, Issue Pt 3, Page(s) 128002

Abstract: Blue algae, a type of harmful microalgae, are responsible for causing harmful algal blooms that result in severe environmental issues. To address this problem, a biopolysaccharide-based flocculant was developed for treating blue algae blooms. This ... ...

Abstract	Blue algae, a type of harmful microalgae, are responsible for causing harmful algal blooms that result in severe environmental issues. To address this problem, a biopolysaccharide-based flocculant was developed for treating blue algae blooms. This flocculant was created by modifying high molecular weight dextran using the natural cationic monomer betaine (Dex-Bet), making it environmentally friendly. Various techniques were used to characterize the prepared Dex-Bet flocculant, including infrared spectroscopy (FTIR), nuclear magnetic resonance hydrogen spectroscopy (
MeSH term(s)	Dextrans ; Kaolin/chemistry ; Wastewater ; Magnetic Resonance Spectroscopy ; Eutrophication ; Flocculation
Chemical Substances	Dextrans ; Kaolin (24H4NWX5CO) ; Wastewater
Language	English
Publishing date	2023-11-09
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2023.128002
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