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  1. Article: [A case of infective endocarditis caused by

    Wang, H Y / Lu, C G / Hu, B F / Hua, W / Huang, L S / Hua, C Z / Chen, Y H

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2024  Volume 62, Issue 3, Page(s) 273–274

    MeSH term(s) Child ; Humans ; Neisseria mucosa ; Endocarditis, Bacterial/etiology ; Endocarditis/complications
    Language Chinese
    Publishing date 2024-02-19
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.cn112140-20231008-00262
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Clinical and etiological characteristics of infectious vulvovaginitis in children in Zhejiang province from 2009 to 2019].

    Gao, H H / Wang, S Y / Zhang, Y C / Zhou, M M / Hua, C Z / Yuan, C Z / Sun, L Y

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2023  Volume 61, Issue 11, Page(s) 1024–1030

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Female ; Adolescent ; Child ; Humans ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Vancomycin/therapeutic use ; Methicillin-Resistant Staphylococcus aureus ; Clindamycin/therapeutic use ; Ceftriaxone/therapeutic use ; Tigecycline/therapeutic use ; Linezolid/therapeutic use ; Levofloxacin/therapeutic use ; Retrospective Studies ; Microbial Sensitivity Tests ; Staphylococcus aureus ; Staphylococcal Infections/drug therapy ; Erythromycin/therapeutic use ; Methicillin ; Penicillin G/therapeutic use ; Escherichia coli ; Drug Resistance, Bacterial
    Chemical Substances Anti-Bacterial Agents ; Vancomycin (6Q205EH1VU) ; Clindamycin (3U02EL437C) ; Ceftriaxone (75J73V1629) ; Tigecycline (70JE2N95KR) ; Linezolid (ISQ9I6J12J) ; Levofloxacin (6GNT3Y5LMF) ; Erythromycin (63937KV33D) ; Methicillin (Q91FH1328A) ; Penicillin G (Q42T66VG0C)
    Language Chinese
    Publishing date 2023-10-29
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.cn112140-20230327-00210
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Clinical characteristics of 84 children with invasive

    Wang, G L / Hua, C Z / Yang, L H / Deng, H L / Xu, H M / Yu, H / Wang, S F / Zhang, C H

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2019  Volume 57, Issue 8, Page(s) 592–596

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adolescent ; Anti-Bacterial Agents/therapeutic use ; Ceftriaxone/therapeutic use ; Cephalosporins/pharmacology ; Cephalosporins/therapeutic use ; Child ; Child, Preschool ; Drug Resistance, Bacterial ; Female ; Haemophilus Infections/diagnosis ; Haemophilus Infections/drug therapy ; Haemophilus Infections/epidemiology ; Haemophilus influenzae/drug effects ; Haemophilus influenzae/isolation & purification ; Humans ; Infant ; Male ; Meningitis/epidemiology ; Microbial Sensitivity Tests ; Pneumonia/epidemiology ; Retrospective Studies ; Treatment Outcome ; beta-Lactamases/metabolism
    Chemical Substances Anti-Bacterial Agents ; Cephalosporins ; Ceftriaxone (75J73V1629) ; beta-Lactamases (EC 3.5.2.6)
    Language Chinese
    Publishing date 2019-07-27
    Publishing country China
    Document type Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.issn.0578-1310.2019.08.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Streptococcal toxic shock syndrome caused by

    Hua, C Z / Yu, H / Yang, L H / Xu, H M / Lyu, Q / Lu, H P / Liu, L Y / Chen, X J / Wang, C Q

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2018  Volume 56, Issue 8, Page(s) 587–591

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adolescent ; Child ; Child, Preschool ; China ; Female ; Humans ; Infant ; Male ; Retrospective Studies ; Shock, Septic/microbiology ; Streptococcal Infections/classification ; Streptococcus pyogenes/pathogenicity
    Language Chinese
    Publishing date 2018-08-04
    Publishing country China
    Document type Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.issn.0578-1310.2018.08.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Report of antimicrobial resistance surveillance program in Chinese children in 2016].

    Wang, C Q / Wang, A M / Yu, H / Xu, H M / Jing, C M / Deng, J K / Zhao, R Z / Hua, C Z / Chen, Y H / Chen, X J / Zhang, T / Zhang, H / Chen, Y P / Yang, J G / Lin, A W / Wang, S F / Cao, Q / Wang, X / Deng, H L /
    Cao, S C / He, J H / Gao, W / Han, S Z

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2018  Volume 56, Issue 1, Page(s) 29–33

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Child ; China ; Drug Resistance, Bacterial ; Gram-Negative Bacteria ; Haemophilus influenzae/drug effects ; Humans ; Klebsiella pneumoniae/drug effects ; Methicillin-Resistant Staphylococcus aureus ; Microbial Sensitivity Tests ; Pseudomonas aeruginosa/drug effects ; beta-Lactamases
    Chemical Substances Anti-Bacterial Agents ; beta-Lactamases (EC 3.5.2.6)
    Language Chinese
    Publishing date 2018-01-02
    Publishing country China
    Document type Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.issn.0578-1310.2018.01.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [An analysis of 181 cases with blood stream infection caused by Streptococcus agalactiae in children from 2011 to 2015: a multi-center retrospective study].

    Hua, C Z / Yu, H / Zhuang, J Q / Li, X L / Xu, H M / Luo, Q E / Lu, H P / Yu, H M / Cao, Y / Chen, Y P / Zhang, T / Jing, C M / Du, L Z / Wang, C Q / Lin, Z L / Zhang, H / Chen, X J / Hua, Z Y

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2016  Volume 54, Issue 8, Page(s) 577–581

    Abstract: Objective: To analyze the clinical characteristics of blood stream infection caused by Streptococcus agalactiae in children and the drug-resistance of the isolates.: Method: All cases with Streptococcus agalactiae growth in blood or cerebrospinal ... ...

    Abstract Objective: To analyze the clinical characteristics of blood stream infection caused by Streptococcus agalactiae in children and the drug-resistance of the isolates.
    Method: All cases with Streptococcus agalactiae growth in blood or cerebrospinal fluid cultures from January 1, 2011 to December 31, 2015 were enrolled by checking the laboratory information system (LIS) from 7 Class 3 Grade A hospitals (4 in Zhejiang, 2 in Shanghai and 1 in Chongqing). Clinical data were collected for analysis. χ(2) test, t test and non parametric test were used in the study.
    Result: One hundred and eighty-one pediatric cases of blood stream infection caused by Streptococcus agalactiae were included in current study. Eighty-six cases (47.5%) were male, and with age range from one day to 9 years (media 13 days). Thirty cases (16.6%) were premature infants and 127 cases (70.2%) were born via vaginal delivery. Seventy-one cases (39.2%) had early onset (<7 d) infections, and 106 cases (58.6%) had late onset (7-89 d) infections. Seventy-eight cases (43.1%) were complicated with purulent meningitis. Incidences of vaginal delivery(81.7%(58/71) vs. 62.3%(66/106)), shortness of breath moaning (43.7%(31/71) vs. 15.1%(16/106)) and preterm premature rupture of membranes (25.4%(18/71) vs. 3.8%(4/106)) were higher in the early onset infection group compared with the late onset group(P all<0.05). However, the number of cases who had fever(25.4%(18/71)vs.85.8%(91/106)) and complicated with purulent meningitis (29.6%(21/71) vs. 53.8%(57/106)) in early onset infections group was less than that in the late onset group(P both<0.05). The blood cultures of most patients (87.8%) were performed before the use of antibiotics. Drug-resistant tests showed that the sensitive rates to penicillin G, ceftriaxone and cefotaxime were 98.9%, 99.0% and 99.0% respectively. All strains were sensitive to vancomucine. The rates of resistance to clindamycin and erythromycin were 68.0% and 34.0%, respectively. Only 39 cases (22.0%) were treated with single antibiotics of either penicillins or cephalosporins, 80 cases (45.2%) were treated with antibiotics containing β lactamase inhibitor, 61 cases (34.5%) were treated with either meropenem or cefoperazone-sulbactam. One hundred and fifty-four cases were cured, while 19 died (including 13 complicated with purulent meningitis) and 8 lost to follow up after giving up of treatment.
    Conclusion: The incidence and mortality of blood stream infection caused by Streptococcus agalactiae complicated with purulent meningitis are high in children. Penicillin is the first choice in treatment. Antibiotics should be selected accorrding to the drug-resistance test.
    MeSH term(s) Anti-Bacterial Agents ; Bacteremia ; Cefotaxime ; Ceftriaxone ; Cephalosporins ; Child ; China ; Clindamycin ; Drug Resistance, Bacterial ; Erythromycin ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Meningitis, Bacterial ; Penicillins ; Retrospective Studies ; Streptococcal Infections/diagnosis ; Streptococcal Infections/drug therapy ; Streptococcus agalactiae
    Chemical Substances Anti-Bacterial Agents ; Cephalosporins ; Penicillins ; Clindamycin (3U02EL437C) ; Erythromycin (63937KV33D) ; Ceftriaxone (75J73V1629) ; Cefotaxime (N2GI8B1GK7)
    Language Chinese
    Publishing date 2016-08
    Publishing country China
    Document type Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.issn.0578-1310.2016.08.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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