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  1. Article: Anelastic Behaviour of Commercial Die-Cast Magnesium Alloys: Effect of Temperature and Alloy Composition.

    Ang, Hua Qian

    Materials (Basel, Switzerland)

    2021  Volume 14, Issue 23

    Abstract: The anelastic deformation, resulting from partial reversal of {101¯2} twinning, is studied at room temperature to 150 °C on several commercial die-cast magnesium alloys for the first time. The magnitude of anelastic strain decreases with increasing ... ...

    Abstract The anelastic deformation, resulting from partial reversal of {101¯2} twinning, is studied at room temperature to 150 °C on several commercial die-cast magnesium alloys for the first time. The magnitude of anelastic strain decreases with increasing temperature. For inter-alloy comparison, AZ91 shows the largest maximum anelastic strain, while AM40 and AM60 show similar maximum anelastic strain. The phenomenon is discussed in terms of solid solution softening and hardening of slip planes and how they influence twinning. T5-aged AE44 consistently shows smaller magnitude of anelasticity compared to as-cast AE44, suggesting that the precipitates formed during ageing may decrease the twin-boundary mobility and further suppress untwinning. Presence of anelasticity poses a challenge to yield strength measurement using the conventional 0.2% offset method, and a more accurate and consistent method of using a higher offset strain or a lower modulus is proposed in this study.
    Language English
    Publishing date 2021-11-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma14237220
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: CAV-1 Overexpression Exacerbates the Manifestation in EPAC-1-Induced Chronic Postsurgical Pain in Rats.

    Hua, Qian / Shen, Shiren / Qin, Yibin / Cao, Su

    Pain research & management

    2022  Volume 2022, Page(s) 8566840

    Abstract: Purpose: Caveolae (CAV) are an invaginated microcapsule with the shape of Ω on the surface of the cell membrane. Caveolin-1 (CAV-1) is involved in neuropathic pain, and adenosine monophosphate (AMP)-exchange protein directly activated by cAMP1 (EPAC-1) ... ...

    Abstract Purpose: Caveolae (CAV) are an invaginated microcapsule with the shape of Ω on the surface of the cell membrane. Caveolin-1 (CAV-1) is involved in neuropathic pain, and adenosine monophosphate (AMP)-exchange protein directly activated by cAMP1 (EPAC-1) is a potential therapeutic target for chronic pain. However, whether EPAC-1 promotes chronic postsurgical pain (CPSP) through CAV-1 has not been reported. Here, we aim to investigate the underlying mechanism of CAV in CPSP.
    Methods: All the rats were divided into 9 groups, including the Naive group, Sham group, skin/muscle incision and retraction (SMIR) group, SMIR + CAV-1 siRNA group, SMIR + control siRNA group, SMIR (7 days)+Saline group, SMIR (7 days)+CE3F4 group, 8-PCPT group, and Saline group. The CPSP rat model was established after SMIR. A mechanical withdrawal threshold (MWT) was recorded to evaluate the animal's behavior. Western blotting and immunofluorescent were performed to detect the protein expression levels of EPAC-1 and P-CAV-1.
    Results: EPAC-1 and CAV-1 were both overexpressed after operation, particularly in astrocytes, microglia, and neurons of spinal marrow (all
    Conclusion: CAV-1 mediates the functional coupling of microglia, astrocytes, and neurons, and thus EPAC-1/CAV-1 plays an important role in CPSP exacerbation.
    MeSH term(s) Animals ; Caveolae/metabolism ; Chronic Pain/etiology ; Chronic Pain/metabolism ; Guanine Nucleotide Exchange Factors/genetics ; Pain, Postoperative/metabolism ; RNA, Small Interfering ; Rats ; Rats, Sprague-Dawley
    Chemical Substances Guanine Nucleotide Exchange Factors ; RNA, Small Interfering
    Language English
    Publishing date 2022-07-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2041085-2
    ISSN 1918-1523 ; 1203-6765
    ISSN (online) 1918-1523
    ISSN 1203-6765
    DOI 10.1155/2022/8566840
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Postbiotics enhance the functionality of a probiotic edible coating for salmon fillets and the probiotic stability during simulated digestion

    Hua, Qian / Wong, Chun Hong / Li, Dan

    Food packaging and shelf life. 2022 Dec., v. 34

    2022  

    Abstract: This study developed a postbiotics fortified probiotic coating for salmon fillets. Postbiotics generated by a pre-fermentation of Lactiplantibacillus plantarum 299 V was added in the coating together with the probiotic bacteria cells. The microbiological ...

    Abstract This study developed a postbiotics fortified probiotic coating for salmon fillets. Postbiotics generated by a pre-fermentation of Lactiplantibacillus plantarum 299 V was added in the coating together with the probiotic bacteria cells. The microbiological analysis results revealed that the fortified coating significantly inhibited the proliferation of psychrophilic bacteria, Pseudomonas spp., Enterobacteriaceae, as well as the spiked Listeria monocytogenes on the salmon fillets during a refrigeration storage of 9 days (P < 0.05). Correspondingly, the generation of biogenic amines and total volatile basic nitrogen was also suppressed significantly by the postbiotics fortified coating (P < 0.05). L. plantarum 299 V on the coated fish fillets manifested excellent stability both during the refrigeration storage and the in vitro simulated digestion. Taken together, the postbiotic fortified probiotic coating reported in this study enhanced the microbial quality and safety of the salmon fillets, and was also recognized as a novel probiotic vector to promote human health.
    Keywords Enterobacteriaceae ; Listeria monocytogenes ; Pseudomonas ; human health ; in vitro digestion ; microbiological quality ; probiotics ; refrigeration ; salmon ; shelf life ; total volatile basic nitrogen
    Language English
    Dates of publication 2022-12
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 2214-2894
    DOI 10.1016/j.fpsl.2022.100954
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Comparison of indoor and outdoor oxidative potential of PM2.5

    Fan Yang / Cong Liu / Hua Qian

    Environment International, Vol 155, Iss , Pp 106684- (2021)

    pollution levels, temporal patterns, and key constituents

    2021  

    Abstract: Oxidative potential (OP) of PM2.5 is an emerging health indicator representing its ability to induce oxidative stress and cause adverse health effects. We examined pollution levels, temporal variations, and key constituents of PM2.5 OP by DTT assay in ... ...

    Abstract Oxidative potential (OP) of PM2.5 is an emerging health indicator representing its ability to induce oxidative stress and cause adverse health effects. We examined pollution levels, temporal variations, and key constituents of PM2.5 OP by DTT assay in both indoor and outdoor environments in Nanjing, China, for over one year. Outdoor OPM (mass-normalized OP characterizes toxicity) and OPV (volume-based OP characterizes overall oxidative burden) in Nanjing were at a medium level compared to results reported for twenty-seven cities. Although PM2.5 mass concentration consistently decreased during outdoor-to-indoor transport, OPM varied by a factor of up to 2 in either direction, indicating a change of PM2.5’s ability to disrupt oxidative-reductive balance. Temporally, both outdoor and indoor OPM exhibited a significant seasonality pattern (P < 0.01) as autumn > summer > spring > winter. Outdoor and indoor daytime-nighttime OPV and OPM are fluctuating within two-fold range. In addition, the change in water-soluble Fe had the highest correlation coefficient (P < 0.05) with ΔOPM (ΔOPM = OPM, in-OPM, out) among constituents measured here. Our results suggest that development of mitigation strategies take indoor PM2.5’s OP into account, instead of outdoors only, since they differ.
    Keywords Dithiothreitol ; Outdoor-indoor OP ; PM2.5 compositions ; Health effects ; Environmental sciences ; GE1-350
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Plasticity of cold and heat stress tolerance induced by hardening and acclimation in the melon thrips.

    Cao, Hua-Qian / Chen, Jin-Cui / Tang, Meng-Qing / Chen, Min / Hoffmann, Ary A / Wei, Shu-Jun

    Journal of insect physiology

    2024  Volume 153, Page(s) 104619

    Abstract: Extreme temperatures threaten species under climate change and can limit range expansions. Many species cope with changing environments through plastic changes. This study tested phenotypic changes in heat and cold tolerance under hardening and ... ...

    Abstract Extreme temperatures threaten species under climate change and can limit range expansions. Many species cope with changing environments through plastic changes. This study tested phenotypic changes in heat and cold tolerance under hardening and acclimation in the melon thrips, Thrips palmi Karny (Thysanoptera: Thripidae), an agricultural pest of many vegetables. We first measured the critical thermal maximum (CT
    MeSH term(s) Animals ; Thysanoptera ; Cold Temperature ; Acclimatization ; Temperature ; Thermotolerance
    Language English
    Publishing date 2024-02-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1879-1611
    ISSN (online) 1879-1611
    DOI 10.1016/j.jinsphys.2024.104619
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Numerical Simulation of Erosion Characteristics for Solid-Air Particles in Liquid Hydrogen Elbow Pipe

    Wenqing Liang / Qining Xun / Zhiyong Shu / Fuming Lu / Hua Qian

    Sustainability, Vol 13, Iss 13303, p

    2021  Volume 13303

    Abstract: The crystalline solid-air in the liquid hydrogen will cause erosion or friction on the elbow, which is directly related to the safety of liquid hydrogen transportation. The CFD-DPM model was used to study the erosion characteristics of solid-air to ... ...

    Abstract The crystalline solid-air in the liquid hydrogen will cause erosion or friction on the elbow, which is directly related to the safety of liquid hydrogen transportation. The CFD-DPM model was used to study the erosion characteristics of solid-air to liquid hydrogen pipelines. Results show that the outer wall of the cryogenic liquid hydrogen elbow has serious erosion in the range of 60–90°, which is different from the general elbow. The erosion rate is linearly positively correlated with the mass flow of solid-air particles, and the erosion rate has a power function relationship with the liquid hydrogen flow rate. The fitted relationship curve can be used to predict the characteristics and range of the elbow erosion. The structure of the liquid hydrogen elbow also has an important influence on the solid-cavity erosion characteristics. The increase of the radius of curvature is conducive to the reduction of the maximum erosion rate, while the average erosion rate undergoes a process of increasing and then decreasing. The radius of curvature is 60 mm, which is the inflection point of the average erosion rate of the 90° elbow. The research results are expected to provide a theoretical basis for the prevention of liquid hydrogen pipeline erosion.
    Keywords liquid hydrogen ; CFD-DPM ; erosion rate ; fitting relationship ; hydrogen safety ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 669
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Study on Interparticle Interaction Force Model to Correct Saturation Density of Real Cryogenic Fluid for LBM Simulation

    Wenqing Liang / Zhiyong Shu / Fuming Lu / Yong Wang / Xiaohong Zheng / Hua Qian

    Sustainability, Vol 14, Iss 7414, p

    2022  Volume 7414

    Abstract: Cryogenic liquefaction energy storage is an important form of storage for sustainable energy liquid hydrogen and other gases. The weighting parameter A in the parameter-adjusted two-phase LBM model is important for the deviation of simulation results. ... ...

    Abstract Cryogenic liquefaction energy storage is an important form of storage for sustainable energy liquid hydrogen and other gases. The weighting parameter A in the parameter-adjusted two-phase LBM model is important for the deviation of simulation results. The aim of this paper is to discover the appropriate parameter to eliminate the deviation, and to solve the problem of large deviation between the theoretical solution and the simulated value that is caused by using different equations of state in LBM simulation. The modified PT equation of state, which is suitable for cryogenic fluids, is combined with the parameter-adjustable two-phase model to simulate the saturation density at different temperatures. Four typical cryogenic fluids—nitrogen, hydrogen, oxygen, and helium—are exploratively simulated to find the suitable parameters to eliminate errors by analyzing the results with theoretical solutions. This is an efficient solution to the deviation between the simulated value and the theoretical solutions, which is caused by the different equation of state in LBM. The optimal A-value of the model based on the PT equation of state was obtained as −0.21, while droplets and bubbles were set into the calculation region, and an inverse relationship between the interface density gradient and temperature was analyzed. The analysis and comparison of the simulation results under the optimal value and the experimental values have laid an important foundation for the phase change simulation of the real cryogenic fluids at the mesoscopic scale.
    Keywords cryogenics ; phase transition ; equation of state ; simulation ; lattice Boltzmann method ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 660
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Associations between home environmental factors and childhood eczema and related symptoms in different cities in China.

    Zhang, Ruosu / Weschler, Louise B / Ye, Jin / Wang, Zhaokun / Deng, Qihong / Li, Baizhan / HuaQian / Zhao, Zhuohui / Zhang, Yinping / Huang, Shaodan / Hong, Chuan

    Heliyon

    2023  Volume 9, Issue 11, Page(s) e21718

    Abstract: Previous studies have shown significant associations between home environmental factors and childhood eczema. However, few studies have compared how associations differ in different regions. This study investigated associations between home environmental ...

    Abstract Previous studies have shown significant associations between home environmental factors and childhood eczema. However, few studies have compared how associations differ in different regions. This study investigated associations between home environmental factors and childhood eczema ever, and related symptoms including itchy rash (IR) and being awakened by itchy rash at night (awake by IR) in 4 cities located in different regions of China, based on cross-sectional investigations during 2010-2012. We used two-step analysis to explore the associations between influencing factors and eczema/related symptoms: first, group Least Absolute Shrinkage and Selection Operator (LASSO) was conducted to identify important factors among a list of candidates; then, the associations in total study population and in each city were estimated using logistic regression. We found these home environmental factors to be risk factors for eczema or related symptoms: large residence size, shared room, air cleaner at home, abnormal smell, perceived dry air, visible mold or damp stains, cooking with coal or wood, painted wall, incense, mice, new furniture during pregnancy, abnormal smell at birth, window condensation at birth and environmental tobacco smoke at birth. Environmental protective factors were rural house location and window ventilation. Associations of factors with eczema/related symptoms differed across cities. For example, air conditioning was protective for eczema in Beijing and awakening by IR in Shanghai with ORs of 0.70 (95%CI: 0.52, 0.95) and 0.33 (95%CI: 0.14, 0.81) respectively, but not significant in other cities. Our results have implications for improving home environments to reduce the risk of childhood eczema/related symptoms in different regions of China.
    Language English
    Publishing date 2023-11-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e21718
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Qualitative and Quantitative Analysis of Five Indoles or Indazole Amide Synthetic Cannabinoids in Suspected E-Cigarette Oil by GC-MS

    Cui-mei LIU / Wei JIA / Chun-hui SONG / Zhen-hua QIAN / Zhen-dong HUA / Yue-meng CHEN

    Fayixue Zazhi, Vol 39, Iss 5, Pp 457-

    2023  Volume 464

    Abstract: Objective To establish the GC-MS qualitative and quantitative analysis methods for the synthetic cannabinoids, its main matrix and additives in suspicious electronic cigarette (e-cigarette) oil samples. Methods The e-cigarette oil samples were analyzed ... ...

    Abstract Objective To establish the GC-MS qualitative and quantitative analysis methods for the synthetic cannabinoids, its main matrix and additives in suspicious electronic cigarette (e-cigarette) oil samples. Methods The e-cigarette oil samples were analyzed by GC-MS after diluted with methanol. Synthetic cannabinoids, its main matrix and additives in e-cigarette oil samples were qualitatively analyzed by the characteristic fragment ions and retention time. The synthetic cannabinoids were quantitatively analyzed by using the selective ion monitoring mode. Results The linear range of each compound in GC-MS quantitative method was 0.025-1 mg/mL, the matrix recovery rate was 94%-103%, the intra-day precision relative standard deviations (RSD) was less than 2.5%, and inter-day precision RSD was less than 4.0%. Five indoles or indazole amide synthetic cannabinoids were detected in 25 e-cigarette samples. The main matrixes of e-cigarette samples were propylene glycol and glycerol. Additives such as N,2,3-trimethyl-2-isopropyl butanamide (WS-23), glycerol triacetate and nicotine were detected in some samples. The content range of synthetic cannabinoids in 25 e-cigarette samples was 0.05%-2.74%. Conclusion The GC-MS method for synthesizing cannabinoid, matrix and additive in e-cigarette oil samples has good selectivity, high resolution, low detection limit, and can be used for simultaneous qualitative and quantitative analysis of multiple components; The explored fragment ion fragmentation mechanism of the electron bombardment ion source of indole or indoxamide compounds helps to identify such substances or other compounds with similar structures in cases.
    Keywords |forensic toxicology|e-cigarette oil|synthetic cannabinoids|gas chromatography-mass spectrometry (gc-ms)|indole|indazole amide ; Medicine ; R
    Subject code 540
    Language Chinese
    Publishing date 2023-10-01T00:00:00Z
    Publisher Editorial Office of Journal of Forensic Medicine
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Effect of starter cultures and spices on physicochemical properties and microbial communities of fermented fish (Suanyu) after fermentation and storage

    Sun, Yingying / Hua, Qian / Tian, Xuyan / Xu, Yanshun / Gao, Pei / Xia, Wenshui

    Food research international. 2022 Sept., v. 159

    2022  

    Abstract: Suanyu is one of the traditional Chinese fermented fish products with a pleasant flavor. The present study sought to evaluate the effects of starter cultures and spices on the physicochemical properties and microbial flora of Suanyu after fermentation ... ...

    Abstract Suanyu is one of the traditional Chinese fermented fish products with a pleasant flavor. The present study sought to evaluate the effects of starter cultures and spices on the physicochemical properties and microbial flora of Suanyu after fermentation and storage. The results indicated that fermentation with mixed starter cultures could lower the pH and inhibit TVB-N formation in Suanyu after fermentation and during storage. Moreover, inoculation of starter cultures could promote free amino acids production during storage. Additionally, inoculation of mixed starter cultures and spices mixture could effectively inhibit the formation of most biogenic amines in Suanyu, revealing the significant role of mixed starter cultures. Staphylococcus, Macrococcus, and Lactobacillus were the core microbial genus in Suanyu. The inoculation of starter cultures could inhibit Enteroccoccus and other microorganisms, while spices introduced Bacillus into Suanyu. The study results provide a theoretical basis for the industrial production and storage of Suanyu.
    Keywords Lactobacillus ; Macrococcus ; Staphylococcus ; fermentation ; fermented fish ; flavor ; food research ; microorganisms ; multiple strain starters ; pH ; total volatile basic nitrogen
    Language English
    Dates of publication 2022-09
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 1111695-x
    ISSN 1873-7145 ; 0963-9969
    ISSN (online) 1873-7145
    ISSN 0963-9969
    DOI 10.1016/j.foodres.2022.111631
    Database NAL-Catalogue (AGRICOLA)

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