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  1. AU="Hua LI"
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  1. Article ; Online: Affective Instability, Depression, and Anxiety Symptoms in a Community Sample of Pregnant and Postpartum Women

    Hua Li

    International Journal of Environmental Research and Public Health, Vol 19, Iss 3171, p

    A Cross-Sectional Study

    2022  Volume 3171

    Abstract: Background: Although perinatal women experience an elevated level of affective instability (AI), limited research has been conducted to examine perinatal AI and its relation to depression and anxiety. The current study investigated correlations between ... ...

    Abstract Background: Although perinatal women experience an elevated level of affective instability (AI), limited research has been conducted to examine perinatal AI and its relation to depression and anxiety. The current study investigated correlations between AI and depression, between AI and anxiety during the perinatal period, and between current depression and anxiety and the latent factors of the Affective Lability Scale-18 (ALS-18). Methods: 202 Canadian perinatal women participated in this cross-sectional study. The ALS-18 was used to assess AI, while the Depression, Anxiety, and Stress Scale-21 measured depression, anxiety, and stress. Multiple logistic regression was performed to investigate the relationship between AI and depression and anxiety, and multiple linear regression was conducted to examine the association between current depression and anxiety and the three latent factors of ALS-18. Results: The findings revealed a significant association between AI and depression and between AI and anxiety. Current depression and anxiety were correlated with ALS-18 factors of depression/anxiety shift and depression/elation shift, while current depression was linked to ALS-18 factor of anger. Conclusions: The study findings have important implications for early detection and intervention of maternal anxiety and depression. In order to improve maternal mental health, AI should be included in routine perinatal check-ups.
    Keywords affective instability ; depression ; anxiety ; perinatal women ; Medicine ; R
    Subject code 150
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Bruceine D and Narclasine inhibit the proliferation of breast cancer cells and the prediction of potential drug targets.

    Xinhao Chen / Hua Li

    PLoS ONE, Vol 19, Iss 1, p e

    2024  Volume 0297203

    Abstract: Background Breast cancer is one of the most common female malignancies. This study explored the underlying mechanism through which the two plant compounds (Brucaine D and Narclasine) inhibited the proliferation of breast cancer cells. Objective The ... ...

    Abstract Background Breast cancer is one of the most common female malignancies. This study explored the underlying mechanism through which the two plant compounds (Brucaine D and Narclasine) inhibited the proliferation of breast cancer cells. Objective The purpose of this study was to explore the effect of Brucaine D and Narclasine on breast cancer development and their potential drug targets. Methods GSE85871 dataset containing 212 samples and the hallmark gene set "h.all.v2023.1.Hs.symbols.gmt" were downloaded from the Gene Expression Omnibus (GEO) database and the Molecular Signatures Database (MSigDB) database, respectively. Principal component analysis (PCA) was applied to classify clusters showing similar gene expression pattern. Single sample gene set enrichment analysis (ssGSEA) was used to calculate the hallmark score for different drug treatment groups. The expressions of genes related to angiogenesis, glycolysis and cell cycle were detected. Protein-protein interaction (PPI) network analysis was performed to study the interaction of the hub genes. Then, HERB database was employed to identify potential target genes for Narclasine and Bruceine D. Finally, in vitro experiments were conducted to validate partial drug-target pair. Results PCA analysis showed that the significant changes in gene expression patterns took place in 6 drugs treatment groups (Narciclasine, Bruceine D, Japonicone A, 1beta-hydroxyalatolactone, Britanin, and four mixture drugs) in comparison to the remaining drug treatment groups. The ssGSEA pathway enrichment analysis demonstrated that Narciclasine and Bruceine treatments had similar enriched pathways, for instance, suppressed pathways related to angiogenesis, Glycolysis, and cell cycle, etc. Further gene expression analysis confirmed that Narciclasine and Bruceine had a strong ability to inhibit these cell cycle genes, and that MYC, CHEK2, MELK, CDK4 and EZH2 were closely interacted with each other in the PPI analysis. Drug target prediction revealed that Androgen Receptor (AR) and ...
    Keywords Medicine ; R ; Science ; Q
    Subject code 572
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Preparation of Hydroxypropyl Chitosan

    Hua LI

    To Chemistry Journal, Vol

    2020  Volume 5

    Abstract: In order to solve poor water solubility of chitosan, chitosan was modified by C6 hydroxyl group. Hydroxypropyl chitosan with good water solubility was prepared by using chitosan as raw material, propylene oxide as etherifying agent and isopropanol as ... ...

    Abstract In order to solve poor water solubility of chitosan, chitosan was modified by C6 hydroxyl group. Hydroxypropyl chitosan with good water solubility was prepared by using chitosan as raw material, propylene oxide as etherifying agent and isopropanol as solvent in alkaline environment. The suitable conditions for etherification reaction were determined by single factor experiments. The results showed that the optimum conditions for the synthesis of hydroxypropyl chitosan were as follows: under the alkaline environment of 25℃, the amount of isopropanol was 25 g, the amount of propylene oxide was 25 g, the amount of chitosan was 2 g, the reaction time was 7 h, the yield of hydroxypropyl chitosan was 25.65%, and the grafting ratio was 68.81%.
    Keywords Chitosan ; Modification ; Hydroxypropyl Chitosan ; Water solubility ; Chemistry ; QD1-999
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher PURKH
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Study on the Influence of Psychological Intervention on Mood State and Coping Styles for High-Level Athletes

    Hua Li

    SAGE Open, Vol

    A Case Study for Wushu Sport in China

    2020  Volume 10

    Abstract: Psychological intervention has a positive impact on the competitive psychological ability and performance of athletes, while there are few studies on this subject. To improve the psychological ability of athletes’ mood and coping styles and promote the ... ...

    Abstract Psychological intervention has a positive impact on the competitive psychological ability and performance of athletes, while there are few studies on this subject. To improve the psychological ability of athletes’ mood and coping styles and promote the smooth progress of the competition, a single-subject experimental design model is used carry out psychological intervention on four high-level athletes for 8 months. According to the characteristics of Wushu routines, the psychological measurement and social validity evaluation are combined to explore the effect of psychological intervention. The results show that the mood state of four athletes improved obviously with the same trend. The coping styles showed a positive upward trend after psychological intervention. The results of three athletes also improved in the City Games. In addition, the results of “social validation” obtained from the coaches and athletes support the effectiveness of the intervention. Psychological intervention can effectively improve the bad mood and negative coping style of Wushu routine athletes so as to improve the competition of athletes.
    Keywords History of scholarship and learning. The humanities ; AZ20-999 ; Social Sciences ; H
    Subject code 796
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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  5. Article ; Online: Preparation of Hydroxypropyl Chitosan

    Hua LI

    To Chemistry Journal, Vol

    2020  Volume 5

    Abstract: In order to solve poor water solubility of chitosan, chitosan was modified by C6 hydroxyl group. Hydroxypropyl chitosan with good water solubility was prepared by using chitosan as raw material, propylene oxide as etherifying agent and isopropanol as ... ...

    Abstract In order to solve poor water solubility of chitosan, chitosan was modified by C6 hydroxyl group. Hydroxypropyl chitosan with good water solubility was prepared by using chitosan as raw material, propylene oxide as etherifying agent and isopropanol as solvent in alkaline environment. The suitable conditions for etherification reaction were determined by single factor experiments. The results showed that the optimum conditions for the synthesis of hydroxypropyl chitosan were as follows: under the alkaline environment of 25℃, the amount of isopropanol was 25 g, the amount of propylene oxide was 25 g, the amount of chitosan was 2 g, the reaction time was 7 h, the yield of hydroxypropyl chitosan was 25.65%, and the grafting ratio was 68.81%.
    Keywords Chitosan ; Modification ; Hydroxypropyl Chitosan ; Water solubility ; Chemistry ; QD1-999
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher PURKH
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

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  6. Article ; Online: Improving Carbon Sequestration Capacity of Forest Vegetation in China

    Li Gao / Hua Li

    Forests, Vol 14, Iss 1077, p

    Afforestation or Forest Management?

    2023  Volume 1077

    Abstract: Both forest management—especially forest tending—and afforestation help to enhance the carbon sequestration of forest vegetation. However, with limited resources, appropriate measures need to be selected to increase the vegetation carbon sinks based on ... ...

    Abstract Both forest management—especially forest tending—and afforestation help to enhance the carbon sequestration of forest vegetation. However, with limited resources, appropriate measures need to be selected to increase the vegetation carbon sinks based on regional endowments. This study aimed to assess the differences in the effects and costs of afforestation and forest tending on vegetation carbon sequestration and to help select suitable afforestation and forest tending areas. In this paper, we used panel fixed effects models to analyze the effects of afforestation and forest tending on vegetation carbon sequestration and conducted a regional heterogeneity analysis to identify suitable afforestation and tending areas. Our results show that the vegetation carbon sequestration capacity of forest tending is 4.48 times higher than that of afforestation, and there is obvious spatial heterogeneity in the effects of afforestation and forest tending on vegetation carbon sequestration. Specifically, the marginal contribution of afforestation is higher than that of tending in northwest and southwest China, whereas the marginal contribution of tending is greater in other regions. Additionally, the afforestation cost for vegetation carbon sequestration is 44.44 times higher than that of tending. Therefore, the management of existing forests must be enhanced, especially in northeastern, southern, and northern China. Similar to the northwest and southwest regions of China, there is still a need to emphasize the use of suitable space for afforestation.
    Keywords plantation ; forest tending ; carbon stock ; effectiveness ; spatial targeting ; Plant ecology ; QK900-989
    Subject code 333
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: High quality and high efficiency fertilization of rice

    Gang-hua LI

    Journal of Integrative Agriculture, Vol 20, Iss 6, Pp 1435-

    2021  Volume 1437

    Keywords Agriculture (General) ; S1-972
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Synthesis of aliphatic nitriles from cyclobutanone oxime mediated by sulfuryl fluoride (SO

    Chen, Xian-Lin / Qin, Hua-Li

    Beilstein journal of organic chemistry

    2023  Volume 19, Page(s) 901–908

    Abstract: ... A ... ...

    Abstract A SO
    Language English
    Publishing date 2023-06-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2192461-2
    ISSN 1860-5397
    ISSN 1860-5397
    DOI 10.3762/bjoc.19.68
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Synthesis of Pyrazolo[1,5-

    Wu, Wen-Qian / Qin, Hua-Li

    The Journal of organic chemistry

    2023  Volume 88, Issue 5, Page(s) 3266–3276

    Abstract: A [3 + 2] cycloaddition reaction ... ...

    Abstract A [3 + 2] cycloaddition reaction of
    Language English
    Publishing date 2023-02-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.2c02242
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  10. Article ; Online: Wave Power Density Hotspot Distribution and Correlation Pattern Exploration in the Gulf of Mexico

    Chengcheng Gu / Hua Li

    Sustainability, Vol 14, Iss 1158, p

    2022  Volume 1158

    Abstract: Wave energy has been studied and explored because of its enormous potential to supply electricity for human activities. However, the uncertainty of its spatial and temporal variations increases the difficulty of harvesting wave energy commercially. There ...

    Abstract Wave energy has been studied and explored because of its enormous potential to supply electricity for human activities. However, the uncertainty of its spatial and temporal variations increases the difficulty of harvesting wave energy commercially. There are no large-scale wave converters in commercial operation yet. A thorough understanding of wave energy dynamic behaviors will definitely contribute to the acceleration of wave energy harvesting. In this paper, about 40 years of meteorological data from the Gulf of Mexico were obtained, visualized, and analyzed to reveal the wave power density hotspot distribution pattern, and its correlation with ocean surface water temperatures and salinities. The collected geospatial data were first visualized in MATLAB. The visualized data were analyzed using the deep learning method to identify the wave power density hotspots in the Gulf of Mexico. By adjusting the temporal and spatial resolutions of the different datasets, the correlations between the number of hotspots and their strength levels and the surface temperatures and salinities are revealed. The R value of the correlation between the wave power density hotspots and the salinity changes from −0.371 to −0.885 in a negative direction, and from 0.219 to 0.771 in a positive direction. For the sea surface temperatures, the R values range from −0.474 to 0.393. Certain areas within the Gulf of Mexico show relatively strong correlations, which may be useful for predicting the wave energy behavior and change patterns.
    Keywords wave power density ; correlation analysis ; deep learning ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 535
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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