LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Ihre letzten Suchen

  1. AU="Huang, Jinghao"
  2. AU="Elagin, A" AU="Elagin, A"

Suchergebnis

Treffer 1 - 10 von insgesamt 31

Suchoptionen

  1. Artikel ; Online: Multi-scale Triplet Hashing for Medical Image Retrieval.

    Chen, Yaxiong / Tang, Yibo / Huang, Jinghao / Xiong, Shengwu

    Computers in biology and medicine

    2023  Band 155, Seite(n) 106633

    Abstract: For medical image retrieval task, deep hashing algorithms are widely applied in large-scale datasets for auxiliary diagnosis due to the retrieval efficiency advantage of hash codes. Most of which focus on features learning, whilst neglecting the ... ...

    Abstract For medical image retrieval task, deep hashing algorithms are widely applied in large-scale datasets for auxiliary diagnosis due to the retrieval efficiency advantage of hash codes. Most of which focus on features learning, whilst neglecting the discriminate area of medical images and hierarchical similarity for deep features and hash codes. In this paper, we tackle these dilemmas with a new Multi-scale Triplet Hashing (MTH) algorithm, which can leverage multi-scale information, convolutional self-attention and hierarchical similarity to learn effective hash codes simultaneously. The MTH algorithm first designs multi-scale DenseBlock module to learn multi-scale information of medical images. Meanwhile, a convolutional self-attention mechanism is developed to perform information interaction of the channel domain, which can capture the discriminate area of medical images effectively. On top of the two paths, a novel loss function is proposed to not only conserve the category-level information of deep features and the semantic information of hash codes in the learning process, but also capture the hierarchical similarity for deep features and hash codes. Extensive experiments on the Curated X-ray Dataset, Skin Cancer MNIST Dataset and COVID-19 Radiography Dataset illustrate that the MTH algorithm can further enhance the effect of medical retrieval compared to other state-of-the-art medical image retrieval algorithms.
    Mesh-Begriff(e) Humans ; COVID-19 ; Algorithms ; Learning ; Semantics ; Skin Neoplasms
    Sprache Englisch
    Erscheinungsdatum 2023-02-08
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 127557-4
    ISSN 1879-0534 ; 0010-4825
    ISSN (online) 1879-0534
    ISSN 0010-4825
    DOI 10.1016/j.compbiomed.2023.106633
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  2. Artikel ; Online: miRNA-124 alleviated memory impairment induced by d-galactose rapidly in male rats via microglia polarization.

    Huang, Jinghao / Chen, Dengchao / Lin, Xinyi / Yang, Chengxia / Lin, Xianzhong

    Hippocampus

    2022  Band 33, Heft 2, Seite(n) 96–111

    Abstract: MiRNA-124 has been considered to play a significant role in the formation of memory and a variety of neurodegenerative diseases. In this study, the aim is to verify whether miRNA-124 is involved in memory impairment induced by d-galactose, and explore ... ...

    Abstract MiRNA-124 has been considered to play a significant role in the formation of memory and a variety of neurodegenerative diseases. In this study, the aim is to verify whether miRNA-124 is involved in memory impairment induced by d-galactose, and explore the underlying neuroprotective mechanism. The results revealed that rapid administration of d-galactose (1000 mg/kg subcutaneously) in mice caused memory impairments, as determined by Novel Object Recognition test, Morris Water Maze test, and histological assessments. MiRNA-124 agomir is stereotactic injected into hippocampus, thus alleviated memory impairment induced by d-galactose and reversed the neural damage and neuroinflammation. Furthermore, the results of molecular biological analysis and immunohistochemistry revealed that miRNA-124 markedly reduced neuroinflammation induced by d-galactose through polarization of microglia as determined by detection of ionized calcium binding adapter molecule 1 (Iba-1), inducible nitric oxide synthase (iNOS) and arginase-1(Arg-1), which also downregulated inflammatory mediators, including interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α), and upregulated IL-4 and IL-10. Hence, taken together, the results of the present study suggested that miRNA-124 showed a significant negative correlation with memory impairment and neuroinflammation induced by d-galactose rapidly, possibly via polarization of microglia from M1 to M2. It is possible that miRNA-124 can be used as a new target for the pathogenesis of memory impairment, including age-associated neurodegenerative diseases such as Alzheimer's disease.
    Mesh-Begriff(e) Rats ; Mice ; Animals ; Male ; Galactose/toxicity ; Galactose/metabolism ; MicroRNAs/metabolism ; Neuroinflammatory Diseases ; Microglia/metabolism ; Memory Disorders/chemically induced ; Memory Disorders/metabolism
    Chemische Substanzen Galactose (X2RN3Q8DNE) ; MicroRNAs ; Mirn124 microRNA, mouse ; MIRN124 microRNA, rat
    Sprache Englisch
    Erscheinungsdatum 2022-12-21
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1074352-2
    ISSN 1098-1063 ; 1050-9631
    ISSN (online) 1098-1063
    ISSN 1050-9631
    DOI 10.1002/hipo.23491
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  3. Artikel ; Online: Rapid qPCR-based quantitative immune cell phenotyping in mouse tissues.

    Huang, Jinghao / Demmler, Richard / Mohamed Abdou, Mariam / Thoma, Oana-Maria / Weigmann, Benno / Waldner, Maximilian J / Stürzl, Michael / Naschberger, Elisabeth

    Journal of investigative medicine : the official publication of the American Federation for Clinical Research

    2023  Band 72, Heft 1, Seite(n) 47–56

    Abstract: The immune microenvironment plays an important role in the regulation of diseases. The characterization of the cellular composition of immune cell infiltrates in diseases and respective models is a major task in pathogenesis research and diagnostics. For ...

    Abstract The immune microenvironment plays an important role in the regulation of diseases. The characterization of the cellular composition of immune cell infiltrates in diseases and respective models is a major task in pathogenesis research and diagnostics. For the assessment of immune cell populations in tissues, fluorescence-activated cell sorting (FACS) or immunohistochemistry (IHC) are the two most common techniques presently applied, but they are cost intensive, laborious, and sometimes limited by the availability of suitable antibodies. Complementary rapid qPCR-based approaches exist for the human situation but are lacking for experimental mouse models. Accordingly, we developed a robust, rapid RT-qPCR-based approach to determine and quantify the abundance of prominent immune cell populations such as T cells, helper T (Th) cells, cytotoxic T cells, Th1 cells, B cells, and macrophages in mouse tissues. The results were independently validated by the gold standards IHC and FACS in corresponding tissues and showed high concordance.
    Mesh-Begriff(e) Humans ; Mice ; Animals ; T-Lymphocytes, Helper-Inducer ; Macrophages
    Sprache Englisch
    Erscheinungsdatum 2023-11-12
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1217870-6
    ISSN 1708-8267 ; 0009-9279 ; 1081-5589
    ISSN (online) 1708-8267
    ISSN 0009-9279 ; 1081-5589
    DOI 10.1177/10815589231210497
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  4. Artikel ; Online: Spatial Effect on the Performance of Carboxylate Anode Materials in Na-Ion Batteries.

    Huang, Jinghao / Li, Shi / Wang, You / Kim, Eric Youngsam / Yang, Zhenzhen / Chen, Dongchang / Cheng, Lei / Luo, Chao

    Small (Weinheim an der Bergstrasse, Germany)

    2023  Band 20, Heft 14, Seite(n) e2308113

    Abstract: Developing low-voltage carboxylate anode materials is critical for achieving low-cost, high-performance, and sustainable Na-ion batteries (NIBs). However, the structure design rationale and structure-performance correlation for organic carboxylates in ... ...

    Abstract Developing low-voltage carboxylate anode materials is critical for achieving low-cost, high-performance, and sustainable Na-ion batteries (NIBs). However, the structure design rationale and structure-performance correlation for organic carboxylates in NIBs remains elusive. Herein, the spatial effect on the performance of carboxylate anode materials is studied by introducing heteroatoms in the conjugation structure and manipulating the positions of carboxylate groups in the aromatic rings. Planar and twisted organic carboxylates are designed and synthesized to gain insight into the impact of geometric structures to the electrochemical performance of carboxylate anodes in NIBs. Among the carboxylates, disodium 2,2'-bipyridine-5,5'-dicarboxylate (2255-Na) with a planar structure outperforms the others in terms of highest specific capacity (210 mAh g
    Sprache Englisch
    Erscheinungsdatum 2023-11-16
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202308113
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  5. Buch ; Online: OCTScenes

    Huang, Yinxuan / Chen, Tonglin / Shen, Zhimeng / Huang, Jinghao / Li, Bin / Xue, Xiangyang

    A Versatile Real-World Dataset of Tabletop Scenes for Object-Centric Learning

    2023  

    Abstract: Humans possess the cognitive ability to comprehend scenes in a compositional manner. To empower AI systems with similar capabilities, object-centric learning aims to acquire representations of individual objects from visual scenes without any supervision. ...

    Abstract Humans possess the cognitive ability to comprehend scenes in a compositional manner. To empower AI systems with similar capabilities, object-centric learning aims to acquire representations of individual objects from visual scenes without any supervision. Although recent advances in object-centric learning have made remarkable progress on complex synthesis datasets, there is a huge challenge for application to complex real-world scenes. One of the essential reasons is the scarcity of real-world datasets specifically tailored to object-centric learning. To address this problem, we propose a versatile real-world dataset of tabletop scenes for object-centric learning called OCTScenes, which is meticulously designed to serve as a benchmark for comparing, evaluating, and analyzing object-centric learning methods. OCTScenes contains 5000 tabletop scenes with a total of 15 objects. Each scene is captured in 60 frames covering a 360-degree perspective. Consequently, OCTScenes is a versatile benchmark dataset that can simultaneously satisfy the evaluation of object-centric learning methods based on single-image, video, and multi-view. Extensive experiments of representative object-centric learning methods are conducted on OCTScenes. The results demonstrate the shortcomings of state-of-the-art methods for learning meaningful representations from real-world data, despite their impressive performance on complex synthesis datasets. Furthermore, OCTScenes can serve as a catalyst for the advancement of existing methods, inspiring them to adapt to real-world scenes. Dataset and code are available at https://huggingface.co/datasets/Yinxuan/OCTScenes.
    Schlagwörter Computer Science - Computer Vision and Pattern Recognition
    Thema/Rubrik (Code) 004 ; 006
    Erscheinungsdatum 2023-06-16
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Zusatzmaterialien

    Kategorien

  6. Artikel ; Online: Metabolite profiling and screening of callus browning‐related genes in lotus (Nelumbo nucifera)

    Deng, Xianbao / Huang, Jinghao / Zhang, Minghua / Wei, Xue / Song, Heyun / Wang, Yuxin / Xin, Jia / Sun, Heng / Liu, Juan / Yang, Dong / Li, Jing / Yang, Mei

    Physiologia Plantarum. 2023 , v. 175, no. 5 p.e14027-

    2023  

    Abstract: Callus browning is a major drawback to lotus callus proliferation and regeneration. However, the underlying mechanism of its formation remains largely unknown. Herein, we aimed to explore the metabolic and molecular basis of lotus callus browning by ... ...

    Abstract Callus browning is a major drawback to lotus callus proliferation and regeneration. However, the underlying mechanism of its formation remains largely unknown. Herein, we aimed to explore the metabolic and molecular basis of lotus callus browning by combining histological staining, high‐throughput metabolomics, and transcriptomic assays for lotus callus at three browning stages. Histological stained brown callus cross sections displayed severe cell death symptoms, accompanied by an obvious accumulation of polyphenols and lignified materials. Widely targeted metabolomics revealed extensively decreased accumulation of most detected flavonoids and benzylisoquinoline alkaloids (BIAs), as well as a few phenolic acids, amino acids and their derivatives in callus with browning symptoms. Conversely, the contents of most detected tannins were significantly increased. Subsequent comparative transcriptomics identified a set of differentially expressed genes (DEGs) associated with the biosynthesis and regulation of flavonoids and BIAs in lotus. Notably, callus browning was coupled with significantly up‐regulated expression of two polyphenol oxidase (PPO) and 17 peroxidase (POD) encoding genes, while the expression of ethylene associated genes remained at marginal levels. These results suggest that lotus callus browning is primarily controlled at the level of metabolism, wherein the oxidation of flavonoids and BIAs is crucially decisive.
    Schlagwörter Nelumbo nucifera ; biosynthesis ; callus ; catechol oxidase ; cell death ; ethylene ; flavonoids ; gene expression regulation ; histology ; metabolites ; metabolomics ; oxidation ; peroxidase ; polyphenols ; transcriptomics
    Sprache Englisch
    Erscheinungsverlauf 2023-09
    Erscheinungsort Blackwell Publishing Ltd
    Dokumenttyp Artikel ; Online
    Anmerkung JOURNAL ARTICLE
    ZDB-ID 2020837-6
    ISSN 1399-3054 ; 0031-9317
    ISSN (online) 1399-3054
    ISSN 0031-9317
    DOI 10.1111/ppl.14027
    Datenquelle NAL Katalog (AGRICOLA)

    Zusatzmaterialien

    Kategorien

  7. Artikel: Trapping tephritid fruit flies (Diptera: Tephritidae) in citrus groves of Fujian Province of China

    Xia, Yulu / Ouyang, Gecheng / Ma, Xingli / Hou, Bohua / Huang, Jinghao / Hu, Hanqing / Fan, Guocheng

    Korean Society of Applied Entomology Journal of Asia-Pacific entomology. 2020 Dec., v. 23, no. 4

    2020  

    Abstract: Certain tephritid fruit flies, such as the oriental fruit fly, Bactrocera dorsalis, the Chinese citrus fly, B. minax and the Japanese orange fly, B. tsuneonis (Diptera: Tephritidae: Dacinae), are destructive citrus pests in China. A two-year trapping ... ...

    Abstract Certain tephritid fruit flies, such as the oriental fruit fly, Bactrocera dorsalis, the Chinese citrus fly, B. minax and the Japanese orange fly, B. tsuneonis (Diptera: Tephritidae: Dacinae), are destructive citrus pests in China. A two-year trapping study was conducted in pomelo, Citrus maxima, groves in Fujian Province of China. The objectives of this study were to investigate the species, the abundance of tephritid fruit flies in the orchards, as well as the efficacy of the selected lure traps to these flies. Four lure traps or devices, i.e. methyl eugenol + Steiner trap (ST), cuelure + ST, ammonium acetate + putrescine + ST, and sticky spheres, were deployed from June to November 2017 and April to October 2018. Six economically significant Dacini pests were trapped during the period. These flies are B. dorsalis, the melon fruit fly, Zeugodacus cucurbitae, the pumpkin fruit fly, Z. tau, the Malaysian fruit fly, B. latifrons, and other two species - B. rubigina and Z. scutellatus. B. dorsalis was the most abundant, accounting for more than 50% of the capture, followed by Z. cucurbitae. The remaining four species accounted for less than 2% of the total capture. B. minax and B. tsuneonis, two destructive citrus-damaging tephritid fruit flies in China, were not found during the trapping period. Methyl eugenol trapped the highest number of fruit flies, followed by cuelure.
    Schlagwörter Bactrocera dorsalis ; Citrus maxima ; Zeugodacus cucurbitae ; accounting ; ammonium acetate ; cue-lure ; entomology ; fruit flies ; groves ; melons ; methyl eugenol ; objectives ; orchards ; pests ; pummelos ; pumpkins ; putrescine ; trapping ; China
    Sprache Englisch
    Erscheinungsverlauf 2020-12
    Umfang p. 879-882.
    Erscheinungsort Elsevier B.V.
    Dokumenttyp Artikel
    Anmerkung NAL-light
    ISSN 1226-8615
    DOI 10.1016/j.aspen.2020.06.005
    Datenquelle NAL Katalog (AGRICOLA)

    Zusatzmaterialien

    Kategorien

  8. Artikel: Substrate pH Influences the Nutrient Absorption and Rhizosphere Microbiome of Huanglongbing-Affected Grapefruit Plants.

    Ferrarezi, Rhuanito Soranz / Lin, Xiongjie / Gonzalez Neira, Andres C / Tabay Zambon, Flavia / Hu, Hanqing / Wang, Xianda / Huang, Jing-Hao / Fan, Guocheng

    Frontiers in plant science

    2022  Band 13, Seite(n) 856937

    Abstract: The substrate pH directly affects nutrient availability in the rhizosphere and nutrient uptake by plants. Macronutrients such as nitrogen, potassium, calcium, magnesium, and sulfur are highly available at pH 6.0-6.5, while micronutrients become less ... ...

    Abstract The substrate pH directly affects nutrient availability in the rhizosphere and nutrient uptake by plants. Macronutrients such as nitrogen, potassium, calcium, magnesium, and sulfur are highly available at pH 6.0-6.5, while micronutrients become less available at higher, alkaline pH (pH > 7.0). Recent research has indicated that low pHs can enhance nutrient uptake and improve sweet orange (
    Sprache Englisch
    Erscheinungsdatum 2022-05-13
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2022.856937
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  9. Artikel ; Online: Halogenated Carboxylates as Organic Anodes for Stable and Sustainable Sodium-Ion Batteries.

    Huang, Jinghao / Callender, Kachief I E / Qin, Kaiqiang / Girgis, Michael / Paige, Mikell / Yang, Zhenzhen / Clayborne, Andre Z / Luo, Chao

    ACS applied materials & interfaces

    2022  Band 14, Heft 36, Seite(n) 40784–40792

    Abstract: Organic materials are competitive as anodes for Na-ion batteries (NIBs) due to the low cost, abundance, environmental benignity, and high sustainability. Herein, we synthesized three halogenated carboxylate-based organic anode materials to exploit the ... ...

    Abstract Organic materials are competitive as anodes for Na-ion batteries (NIBs) due to the low cost, abundance, environmental benignity, and high sustainability. Herein, we synthesized three halogenated carboxylate-based organic anode materials to exploit the impact of halogen atoms (F, Cl, and Br) on the electrochemical performance of carboxylate anodes in NIBs. The fluorinated carboxylate anode, disodium 2, 5-difluoroterephthalate (DFTP-Na), outperforms the other carboxylate anodes with H, Cl, and Br, in terms of high specific capacity (212 mA h g
    Sprache Englisch
    Erscheinungsdatum 2022-09-01
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.2c07383
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  10. Artikel ; Online: A Fast-Charging and High-Temperature All-Organic Rechargeable Potassium Battery.

    Qin, Kaiqiang / Holguin, Kathryn / Huang, Jinghao / Mohammadiroudbari, Motahareh / Chen, Fu / Yang, Zhenzhen / Xu, Gui-Liang / Luo, Chao

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2022  Band 9, Heft 34, Seite(n) e2106116

    Abstract: Developing fast-charging, high-temperature, and sustainable batteries is critical for the large-scale deployment of energy storage devices in electric vehicles, grid-scale electrical energy storage, and high temperature regions. Here, a transition metal- ... ...

    Abstract Developing fast-charging, high-temperature, and sustainable batteries is critical for the large-scale deployment of energy storage devices in electric vehicles, grid-scale electrical energy storage, and high temperature regions. Here, a transition metal-free all-organic rechargeable potassium battery (RPB) based on abundant and sustainable organic electrode materials (OEMs) and potassium resources for fast-charging and high-temperature applications is demonstrated. N-doped graphene and a 2.8 m potassium hexafluorophosphate (KPF
    Sprache Englisch
    Erscheinungsdatum 2022-10-31
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202106116
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

Zum Seitenanfang