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  1. Book: Ocular inflammatory disease and uveitis manual

    Huang, John J. / Gaudio, Paul A.

    diagnosis and treatment

    2010  

    Author's details ed. by John J. Huang ; Paul A. Gaudio
    Keywords Uveitis ; Eye Infections
    Language English
    Size X, 255 S. : Ill., 26 cm
    Publisher Wolters Kluwer, Lippincott Williams & Wilkins
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT016383603
    ISBN 978-0-7817-9836-5 ; 0-7817-9836-1
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Online: Ocular inflammatory disease and uveitis manual

    Huang, John J. / Gaudio, Paul A.

    diagnosis and treatment

    2010  

    Author's details edited by John J. Huang, Paul A. Gaudio
    Keywords Uveitis ; Eye infections
    Language English
    Size 1 Online-Ressource
    Publisher Wolters Kluwer/Lippincott Williams & Wilkins Health
    Publishing place Philadelphia
    Document type Book ; Online
    Note Includes bibliographical references and index
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 978-0-7817-9836-5 ; 0-7817-9836-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article: Intraocular metastasis of testicular natural killer T-cell lymphoma with diffuse retinal pigment epithelium changes.

    Huang, John J

    Retinal cases & brief reports

    2011  Volume 5, Issue 1, Page(s) 42–45

    Abstract: Purpose: The purpose of this study was to report the first confirmed case of testicular natural killer T-cell lymphoma with bilateral intraocular metastasis.: Methods: The author presents a chart review of a patient with testicular natural killer T- ... ...

    Abstract Purpose: The purpose of this study was to report the first confirmed case of testicular natural killer T-cell lymphoma with bilateral intraocular metastasis.
    Methods: The author presents a chart review of a patient with testicular natural killer T-cell lymphoma metastasis to both eyes. This patient was treated with systemic chemotherapy, radiation, and intravitreal injections of methotrexate.
    Results: The author identified one case of a patient with the diagnosis of bilateral metastatic natural killer T-cell lymphoma with ocular involvement treated with intravitreal methotrexate. After treatment, the patient developed diffuse widespread retinal pigment epithelium alterations in giraffe-like patterns.
    Conclusion: This represents a clinical case of a patient with primary testicular natural killer T-cell lymphoma and ocular metastasis with posttreatment retinal changes resembling bilateral diffuse uveal melanocytic proliferation.
    Language English
    Publishing date 2011
    Publishing country United States
    Document type Journal Article
    ISSN 1935-1089
    ISSN 1935-1089
    DOI 10.1097/ICB.0b013e3181c333bc
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Routes for Drug Delivery: Sustained-Release Devices.

    Yun, Samuel / Huang, John J

    Developments in ophthalmology

    2016  Volume 55, Page(s) 84–92

    Abstract: Several different technologies exist for sustained-release drug delivery devices, including: (1) nonbiodegradable implants; (2) biodegradable implants; (3) micro- and nanoparticles; (4) liposomes, and (5) encapsulated cell technology (ECT). Currently, ... ...

    Abstract Several different technologies exist for sustained-release drug delivery devices, including: (1) nonbiodegradable implants; (2) biodegradable implants; (3) micro- and nanoparticles; (4) liposomes, and (5) encapsulated cell technology (ECT). Currently, the only sustained-release devices approved by the Food and Drug Administration are the ganciclovir implant for the treatment of cytomegalovirus retinitis, the fluocinolone acetonide implant for the treatment of noninfectious posterior uveitis and the dexamethasone implant for the treatment of diabetic macular edema or noninfectious posterior uveitis. The first two implants are nonbiodegradable and require surgical placement, whereas the dexamethasone implant is biodegradable, and can be shaped and injected using a small-gauge needle or applicator into the vitreous. ECT, currently in a phase II clinical trial, utilizes modified retinal pigment epithelium cells to produce protein drug molecules in the vitreous. The microparticle, nanoparticle and liposome technology currently in development may offer the most flexibility for prolonged drug release and combination therapy for retinal diseases.
    MeSH term(s) Delayed-Action Preparations ; Drug Administration Routes ; Drug Delivery Systems ; Drug Implants ; Humans ; Liposomes ; Nanoparticles ; Retinal Diseases/drug therapy
    Chemical Substances Delayed-Action Preparations ; Drug Implants ; Liposomes
    Language English
    Publishing date 2016
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ISSN 1662-2790 ; 0250-3751
    ISSN (online) 1662-2790
    ISSN 0250-3751
    DOI 10.1159/000434692
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Ocular manifestations of systemic inflammatory diseases.

    Mohsenin, Amir / Huang, John J

    Connecticut medicine

    2012  Volume 76, Issue 9, Page(s) 533–544

    Abstract: Inflammation of the eye is often times seen in association with systemic inflammatory diseases. Understanding the various forms of ocular involvement in these conditions is important as untreated ophthalmic involvement can lead to severe vision loss. In ... ...

    Abstract Inflammation of the eye is often times seen in association with systemic inflammatory diseases. Understanding the various forms of ocular involvement in these conditions is important as untreated ophthalmic involvement can lead to severe vision loss. In addition to providing a basic framework for diagnosis and treatment, this review will highlight the ocular manifestations of the following systemic inflammatory conditions: rheumatoid arthritis, systemic lupus erythematosus, Wegener's granulomatosis, Sjögren's syndrome, polyarteritisnodosa, primary antiphospholipid syndrome, Behçet's syndrome, Kawasaki disease, Cogan's syndrome and relapsing polychondritis.
    MeSH term(s) Antiphospholipid Syndrome/complications ; Antiphospholipid Syndrome/diagnosis ; Arthritis, Rheumatoid/complications ; Arthritis, Rheumatoid/diagnosis ; Autoimmune Diseases/complications ; Autoimmune Diseases/diagnosis ; Autoimmune Diseases/physiopathology ; Behcet Syndrome/complications ; Behcet Syndrome/diagnosis ; Cogan Syndrome/complications ; Cogan Syndrome/diagnosis ; Eye Diseases/diagnosis ; Eye Diseases/etiology ; Eye Diseases/physiopathology ; Granulomatosis with Polyangiitis/complications ; Granulomatosis with Polyangiitis/diagnosis ; Humans ; Inflammation/complications ; Lupus Erythematosus, Systemic/complications ; Lupus Erythematosus, Systemic/diagnosis ; Mucocutaneous Lymph Node Syndrome/complications ; Mucocutaneous Lymph Node Syndrome/diagnosis ; Polychondritis, Relapsing/complications ; Polychondritis, Relapsing/diagnosis ; Polychondritis, Relapsing/physiopathology ; Sjogren's Syndrome/complications ; Sjogren's Syndrome/diagnosis ; Vasculitis/complications ; Vasculitis/diagnosis ; Vasculitis/physiopathology
    Language English
    Publishing date 2012-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 412600-2
    ISSN 0010-6178
    ISSN 0010-6178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Central retinal vein occlusion resulting from anomalous retinal vascular anatomy in a 24-year-old man.

    Kavoussi, Shaheen C / Kempton, James E / Huang, John J

    Clinical ophthalmology (Auckland, N.Z.)

    2015  Volume 9, Page(s) 885–887

    Abstract: An otherwise healthy 24-year-old man presented with a painless decrease of vision in the left eye for 2 days. Best-corrected visual acuity was 20/20 in the right eye and 20/80 in the left eye. Anterior exam was unremarkable and funduscopic exam in the ... ...

    Abstract An otherwise healthy 24-year-old man presented with a painless decrease of vision in the left eye for 2 days. Best-corrected visual acuity was 20/20 in the right eye and 20/80 in the left eye. Anterior exam was unremarkable and funduscopic exam in the left eye revealed retinal hemorrhages in all four quadrants with venous dilation and tortuosity consistent with central retinal vein occlusion. Fluorescein angiography revealed delayed venous filling with neither leakage nor vasculitis. A comprehensive work-up that included infectious, inflammatory, and hypercoagulability studies was unremarkable, and magnetic resonance imaging of the orbits was unrevealing. After 2 months, best-corrected visual acuity returned to 20/20-2 in the left eye. Upon closer review of the vascular anatomy in the left eye, a bifurcation of the central retinal artery at the level of the optic disc was tightly intertwined with an undilated nasal retinal vein in a manner that appeared to compress the underlying central retinal vein, resulting in dilation and tortuosity of the remaining venous branches. The vessel wall damage, turbulent venous flow, and compressive mass effect resulting from the anomalous retinal vasculature relationship is the proposed mechanism of the central retinal vein occlusion. Careful attention to the retinal vascular anatomy is suggested to aid in assessing the risk of retinal vein occlusion in any age group.
    Language English
    Publishing date 2015-05-20
    Publishing country New Zealand
    Document type Case Reports
    ISSN 1177-5467
    ISSN 1177-5467
    DOI 10.2147/OPTH.S84214
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Ocular inflammatory disease and uveitis manual

    Huang, John J / Gaudio, Paul A

    diagnosis and treatment

    2010  

    Author's details edited by John J. Huang, Paul A. Gaudio
    MeSH term(s) Uveitis ; Eye Infections
    Language English
    Size x, 255 p. :, ill.
    Publisher Wolters Kluwer/Lippincott Williams & Wilkins
    Publishing place Philadelphia
    Document type Book
    ISBN 9780781798365 ; 0781798361
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Article ; Online: Subretinal fibrosis and uveitis syndrome in a patient with ectodermal dysplasia.

    Huffman, Ryan I / Huang, John J

    Ocular immunology and inflammation

    2009  Volume 17, Issue 5, Page(s) 348–350

    Abstract: Purpose: To report a case of subretinal fibrosis and uveitis syndrome in association with ectodermal dysplasia.: Methods: Chart review of a patient with subretinal fibrosis and uveitis syndrome and ectodermal dysplasia.: Results: The authors ... ...

    Abstract Purpose: To report a case of subretinal fibrosis and uveitis syndrome in association with ectodermal dysplasia.
    Methods: Chart review of a patient with subretinal fibrosis and uveitis syndrome and ectodermal dysplasia.
    Results: The authors identified one case of a patient with the diagnoses of subretinal fibrosis and uveitis syndrome and ectodermal dysplasia.
    Conclusions: This represents an uncommon case of a patient with the diagnoses of both subretinal fibrosis and uveitis syndrome and ectodermal dysplasia.
    MeSH term(s) Adult ; Ectodermal Dysplasia/complications ; Female ; Fibrosis ; Fluorescein Angiography ; Fundus Oculi ; Humans ; Macular Edema/complications ; Retinal Diseases/complications ; Retinal Diseases/diagnosis ; Retinal Diseases/pathology ; Syndrome ; Tomography, Optical Coherence ; Uveitis/complications
    Language English
    Publishing date 2009-09
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1193873-0
    ISSN 1744-5078 ; 0927-3948
    ISSN (online) 1744-5078
    ISSN 0927-3948
    DOI 10.3109/09273940903168670
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Choroiditis in a patient with multiple sclerosis.

    Correnti, Anthony J / Huang, John J

    Ocular immunology and inflammation

    2008  Volume 16, Issue 5, Page(s) 233–235

    Abstract: Purpose: To describe choroiditis in multiple sclerosis (MS).: Design: Case report.: Methods: Clinical findings, fluorescein angiography, optical coherence tomography, and treatment are presented. A 50-year-old man with MS presented with vitritis ... ...

    Abstract Purpose: To describe choroiditis in multiple sclerosis (MS).
    Design: Case report.
    Methods: Clinical findings, fluorescein angiography, optical coherence tomography, and treatment are presented. A 50-year-old man with MS presented with vitritis and multiple choroidal lesions in the fovea and periphery in both eyes. Fluorescein angiography (FA) revealed early hyperfluorescence and late leakage of the lesions. Optical coherence tomography showed subretinal fluid in the right eye. One month post-treatment, visual acuity returned to the baseline with complete resolution of subretinal fluid and decreased leakage on FA.
    Conclusions: Choroiditis might be related to MS, but may also be a chance occurrence.
    MeSH term(s) Administration, Oral ; Choroiditis/complications ; Choroiditis/diagnosis ; Choroiditis/drug therapy ; Choroiditis/physiopathology ; Drug Administration Schedule ; Fluorescein Angiography ; Follow-Up Studies ; Fundus Oculi ; Humans ; Male ; Middle Aged ; Multiple Sclerosis/complications ; Mycophenolic Acid/administration & dosage ; Mycophenolic Acid/analogs & derivatives ; Prednisolone/administration & dosage ; Tomography, Optical Coherence ; Visual Acuity/drug effects
    Chemical Substances Prednisolone (9PHQ9Y1OLM) ; Mycophenolic Acid (HU9DX48N0T)
    Language English
    Publishing date 2008-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1193873-0
    ISSN 1744-5078 ; 0927-3948
    ISSN (online) 1744-5078
    ISSN 0927-3948
    DOI 10.1080/09273940802217859
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Necrobiotic xanthogranuloma and chronic lymphocytic leukemia of the conjunctiva masquerading as scleritis and uveitis.

    Mohsenin, Amir / Sinard, John / Huang, John J

    Clinical ophthalmology (Auckland, N.Z.)

    2012  Volume 6, Page(s) 2045–2047

    Abstract: This report describes a unique case of coexisting necrobiotic xanthogranuloma and chronic lymphocytic leukemia in a patient presenting with scleritis and uveitis. A 53-year-old Caucasian man diagnosed with anterior uveitis and scleritis for the prior ... ...

    Abstract This report describes a unique case of coexisting necrobiotic xanthogranuloma and chronic lymphocytic leukemia in a patient presenting with scleritis and uveitis. A 53-year-old Caucasian man diagnosed with anterior uveitis and scleritis for the prior year was referred to our uveitis clinic for further evaluation. Prior uveitis/scleritis workup performed by the referring ophthalmologist was negative. Examination demonstrated unilateral uveitis and posterior scleritis along with bilateral conjunctival lesions. Incisional biopsy of the conjunctiva was carried out. The excised tissue was sent fresh for histopathologic studies. Slit-lamp examination revealed bilateral yellow-white bulbar conjunctival lesions, 1+ conjunctival injection OU, stellate keratic precipitates OS with 25 cells per high-powered field. Funduscopic examination was significant for subretinal fluid OS. Conjunctival biopsy revealed necrobiotic xanthogranuloma and chronic lymphocytic leukemia. Systemic workup demonstrated paraproteinemia consistent with necrobiotic xanthogranuloma and a complete blood count consistent with leukemia. This case demonstrates an atypical presentation of necrobiotic xanthogranuloma and concomitant chronic lymphocytic leukemia presenting in the form of uveitis, scleritis, and conjunctival infiltration. Masquerade syndromes, such as necrobiotic xanthogranuloma and leukemia, must be kept in mind when treating patients with uveitis or scleritis with negative workups.
    Language English
    Publishing date 2012-12-13
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2415713-2
    ISSN 1177-5483 ; 1177-5483
    ISSN (online) 1177-5483
    ISSN 1177-5483
    DOI 10.2147/OPTH.S35743
    Database MEDical Literature Analysis and Retrieval System OnLINE

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