Article ; Online: Simultaneous quantification combined with multivariate statistical analysis of multiple chemical markers of Wu Ji Bai Feng Pill by UHPLC-MS/MS.
Journal of food and drug analysis
2018 Volume 27, Issue 1, Page(s) 275–283
Abstract: Wu Ji Bai Feng Pill (WJBFP) is a traditional Chinese medicine (TCM) complex formula, which has been widely used in the treatment of various gynecological disorders. However, the quality control of multiple components in WJBFP is challengeable by using ... ...
| Abstract | Wu Ji Bai Feng Pill (WJBFP) is a traditional Chinese medicine (TCM) complex formula, which has been widely used in the treatment of various gynecological disorders. However, the quality control of multiple components in WJBFP is challengeable by using the methods applicable to analysis of several phytochemicals in single herbs or simple herbal preparations. The purpose of this study is to establish an ultra-high performance liquid chromatography coupled with triple quadrupole mass spectrometry (UHPLC-MS/MS) method for the quantitative determination of 20 bioactive compounds in WJBFP. The modified chromatographic conditions were achieved on an Agilent Poroshell 120 EC-C |
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| MeSH term(s) | Chromatography, High Pressure Liquid/methods ; Drugs, Chinese Herbal/chemistry ; Limit of Detection ; Medicine, Chinese Traditional ; Multivariate Analysis ; Principal Component Analysis ; Tandem Mass Spectrometry/methods |
| Chemical Substances | Drugs, Chinese Herbal |
| Language | English |
| Publishing date | 2018-10-25 |
| Publishing country | China (Republic : 1949- ) |
| Document type | Evaluation Study ; Journal Article ; Research Support, Non-U.S. Gov't |
| ISSN | 2224-6614 |
| ISSN (online) | 2224-6614 |
| DOI | 10.1016/j.jfda.2018.10.004 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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