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  1. Article: A study on the appropriate dose of rocuronium for intraoperative neuromonitoring in Da Vinci robot thyroid surgery: a randomized, double-blind, controlled trial.

    Lan, Jianning / Huang, Qijian / Su, Jiansheng / Zhang, Xuru / Zhang, Liangcheng

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1216546

    Abstract: Background: This study was to explore the effect of different doses of rocuronium bromide on neuromonitoring during Da Vinci robot thyroid surgery.: Methods: This was a prospective, randomized, double-blind, controlled trial that included 189 ... ...

    Abstract Background: This study was to explore the effect of different doses of rocuronium bromide on neuromonitoring during Da Vinci robot thyroid surgery.
    Methods: This was a prospective, randomized, double-blind, controlled trial that included 189 patients who underwent Da Vinci robot thyroidectomy with intraoperative neuromonitoring(IONM). Patients were randomly divided into three groups and given three different doses of rocuronium (0.3mg/kg, 0.6mg/kg, 0.9mg/kg). Outcome measurements included IONM evoked potential, postoperative Voice Handicap Index-30(VHI-30), intraoperative body movement incidence rate, Cooper score, and hemodynamic changes during anesthesia induction.Results: The difference in IONM evoked potentials at various time points between the three groups was not statistically significant (P>0.05). The difference in Cooper scores and intraoperative body movement incidence rate between 0.6 and 0.9mg/kg groups was statistically significant compared with the 0.3mg/kg group (both P<0.001). There was no statistically significant difference in VHI-30 score and hemodynamic changes during anesthesia induction among the three groups (both P>0.05).
    Conclusions: For patients undergoing Da Vinci robot thyroidectomy, a single dose of rocuronium at 0.6 and 0.9mg/kg during anesthesia induction can provide stable IONM evoked potential. Additionally, compared to 0.3 mg/kg, it can offer better tracheal intubation conditions and lower incidence of body movements during surgery. It is worth noting that the use of higher doses of rocuronium should be adjusted based on the duration of IONM and local practices.
    MeSH term(s) Humans ; Thyroid Gland/surgery ; Rocuronium ; Prospective Studies ; Robotics ; Robotic Surgical Procedures
    Chemical Substances Rocuronium (WRE554RFEZ)
    Language English
    Publishing date 2023-09-07
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1216546
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Association between preoperative anemia and postoperative short-term outcomes in patients undergoing colorectal cancer surgery - a propensity score matched retrospective cohort study.

    Yan, Ting / Lei, Shaohui / Zhou, Bingbing / Huang, Yaqi / Li, Xiaoting / Zhang, Jiaqi / Huang, Qijian / Zhang, Liangcheng

    BMC anesthesiology

    2023  Volume 23, Issue 1, Page(s) 307

    Abstract: Background: Based on previous studies which failed to analyze important confounding variables, the association between preoperative anemia and outcomes of patients who underwent colorectal cancer (CRC) surgery has not been clearly demonstrated. This ... ...

    Abstract Background: Based on previous studies which failed to analyze important confounding variables, the association between preoperative anemia and outcomes of patients who underwent colorectal cancer (CRC) surgery has not been clearly demonstrated. This study aimed to investigate the relationship between preoperative anemia and short-term outcomes in patients with CRC.
    Methods: Data from a retrospective collective database of patients who underwent CRC surgery at our hospital between September 1, 2019 and September 30, 2021 were retrieved and analyzed, and the short-term postoperative outcomes of anemic (hemoglobin < 120 g dL
    Results: After excluding some cases, the remaining 1894 patients had complete data available for analysis. The incidence of preoperative anemia was 39.8% (754/1894). Before PSM, preoperative anemia patients had a higher risk of major morbidity than non-anemia patients (27.2% vs. 23.1%, odds ratio [OR] 1.245, 95% confidence interval [CI] 1.008-1.538, P = 0.042). After PSM was performed in the cohort, 609 patients remained in the anemic and non-anemic groups. The incidence of major morbidity (25.8% vs. 24.0%, OR 1.102, 95% CI 0.849-1.429, P = 0.446) between anemic and non-anemic patients was comparable. No significant difference was found between the anemic and non-anemic groups in postoperative length of stay (8.0 [6.0-12.0] vs. 8.0 [7.0-11.0], P = 0.311). The sensitivity analysis results were in accordance with the primary outcome. Furthermore, we did not ascertain any discernible correlation between the extent of anemia and significant major morbidity.
    Conclusions: Compared with preoperative non-anemia, anemia status does not seem to be associated with major morbidity in patients with CRC surgery. It is noteworthy that, anemia is insufficient as a solitary risk factor and may be a better marker of poor health resulting from multiple factors.
    Trial registration: Registration Authority: Chinese Clinical Trial Registry; Registration number and date: ChiCTR2100049696, 08/08/2021; Principal investigator: Ting Yan; Link to trial registry: http://www.chictr.org.cn/showproj.aspx?proj=131698

    .
    MeSH term(s) Humans ; Female ; Male ; Retrospective Studies ; Propensity Score ; Anemia/complications ; Anemia/epidemiology ; Digestive System Surgical Procedures ; Colorectal Neoplasms/complications ; Colorectal Neoplasms/surgery
    Language English
    Publishing date 2023-09-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2091252-3
    ISSN 1471-2253 ; 1471-2253
    ISSN (online) 1471-2253
    ISSN 1471-2253
    DOI 10.1186/s12871-023-02270-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Modified long-axis in-plane ultrasound-guided radial artery cannulation in adult patients: A randomized controlled trial.

    Wang, Jiebo / Weng, Xianfeng / Huang, Qijian / Lai, Zhongmeng / Zhao, Zisong / Lan, Jianning / Wu, Guohua / Lin, Lei / Su, Jiansheng / Liu, Junle / Zhang, Liangcheng

    Anaesthesia, critical care & pain medicine

    2021  Volume 41, Issue 1, Page(s) 100989

    Abstract: Introduction: For adults with small radial arteries, ultrasound-guided radial artery cannulation remains challenging and the relevant data is currently lacking. The study aimed to test the hypothesis that modified long-axis in-plane ultrasound guidance ( ...

    Abstract Introduction: For adults with small radial arteries, ultrasound-guided radial artery cannulation remains challenging and the relevant data is currently lacking. The study aimed to test the hypothesis that modified long-axis in-plane ultrasound guidance (M-LAIP) would improve success rates of radial artery cannulation in this population.
    Patients and methods: This was a prospective, randomised, and controlled clinical study that enrolled 201 adult patients with diameters of the radial artery less than 2.2 mm. Patients were randomised to M-LAIP, short-axis out-of-plane (SAOP), or conventional palpation (C-P) group according to different approaches of radial artery cannulation (M-LAIP, SAOP, and C-P). Outcome measurements included the success rate, cannulation time, and cannulation-related adverse events.
    Results: The cannulation success rate was significantly higher in the M-LAIP group than in the SAOP or C-P groups (first success rate: 80.3% vs. 53.8% or 33.8%; P < 0.001; total success rate: 93.9% vs. 78.5% or 50.8%; P < 0.001). Total cannulation time in the M-LAIP group was shorter than that in the SAOP group (P = 0.002) or the C-P group (P < 0.001). The rates of posterior wall puncture and haematoma in the M-LAIP group were lower than that in the SAOP group or C-P group (P < 0.008).
    Conclusion: The use of the M-LAIP approach significantly improved the success rate of radial artery cannulation, shortened procedure time, and lowered the rates of posterior wall puncture and haematoma in adults with radial artery diameters less than 2.2 mm, compared with that achieved by the SAOP or C-P approach.
    MeSH term(s) Adult ; Catheterization, Peripheral/adverse effects ; Catheterization, Peripheral/methods ; Humans ; Prospective Studies ; Radial Artery/diagnostic imaging ; Ultrasonography, Interventional/methods
    Language English
    Publishing date 2021-12-03
    Publishing country France
    Document type Journal Article ; Randomized Controlled Trial
    ISSN 2352-5568
    ISSN (online) 2352-5568
    DOI 10.1016/j.accpm.2021.100989
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  4. Article ; Online: Monitoring the end-tidal concentration of sevoflurane for preventing awareness during anesthesia (MEETS-PANDA): A prospective clinical trial.

    Wang, Jiebo / Zhang, Liangcheng / Huang, Qijian / Wu, Guohua / Weng, Xianfeng / Lai, Zhongmeng / Lin, Pengtao

    International journal of surgery (London, England)

    2017  Volume 41, Page(s) 44–49

    Abstract: Objective: It was hypothesized that monitoring end-tidal sevoflurane (ETS) during endoscopic surgery could reduce the incidence of intraoperative awareness in patients undergoing general anesthesia. Herein, the incidence of intraoperative awareness and ... ...

    Abstract Objective: It was hypothesized that monitoring end-tidal sevoflurane (ETS) during endoscopic surgery could reduce the incidence of intraoperative awareness in patients undergoing general anesthesia. Herein, the incidence of intraoperative awareness and other correlative factors was recorded and compared.
    Methods: Two thousand five hundred ASA I-III patients aged 18-80 years who underwent general anesthesia were randomly divided into 2 groups (n = 1250): routine care group (R) and ETS concentration group (E). ETS concentration was monitored in group E and maintained at a sevoflurane minimum alveolar concentration (MAC) of 0.7-1.3; group R was monitored using routine care, and the sevoflurane was maintained. Patients were assessed for intraoperative awareness with a questionnaire on their explicit memory 24-48 h after surgery.
    Results: A total of 2532 patients were selected, and 86 patients were excluded. As for the groups, 1219 patients were assigned to group E, and 1227 patients were assigned to group R. As for intraoperative awareness, group E had 2 patients, and group R had 14. Compared with group R, the incidence of intraoperative awareness in group E was significantly lower (p = 0.003); the time-averaged ETS concentration and sevoflurane dosage were lower in group E (p < 0.05); and no significant changes were found in tracheal extubation time, intravenous general anesthetic dosage, or postoperative complication incidence in either group (p > 0.05). The incidence of intraoperative awareness was higher in women than men in group R (p < 0.05).
    Conclusion: Using ETS-guided anesthesia and maintaining the sevoflurane concentration (0.7-1.3 MAC) can decrease the incidence of patient awareness during endoscopic surgery.
    Language English
    Publishing date 2017-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1016/j.ijsu.2017.03.015
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    Zs.A 6502: Show issues Location:
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  5. Article ; Online: Modified long-axis in-plane ultrasound technique versus conventional palpation technique for radial arterial cannulation: A prospective randomized controlled trial.

    Wang, Jiebo / Lai, Zhongmeng / Weng, Xianfeng / Lin, Yong / Wu, Guohua / Su, Jiansheng / Huang, Qijian / Zeng, Jian / Liu, Junle / Zhao, Zisong / Yan, Ting / Zhang, Liangcheng / Zhou, Linying

    Medicine

    2020  Volume 99, Issue 2, Page(s) e18747

    Abstract: Background: A low first-pass success rate of radial artery cannulation was obtained when using the conventional palpation technique (C-PT) or conventional ultrasound-guided techniques, we; therefore, evaluate the effect of a modified long-axis in-plane ... ...

    Abstract Background: A low first-pass success rate of radial artery cannulation was obtained when using the conventional palpation technique (C-PT) or conventional ultrasound-guided techniques, we; therefore, evaluate the effect of a modified long-axis in-plane ultrasound technique (M-LAINUT) in guiding radial artery cannulation in adults.
    Methods: We conducted a prospective, randomized and controlled clinical trial of 288 patients undergoing radial artery cannulation. Patients were randomized 1:1 to M-LAINUT or C-PT group at Fujian Medical University Union Hospital between 2017 and 2018. Radial artery cannulation was performed by 3 anesthesiologists with different experience. The outcome was the first and total radial artery cannulation success rates, the number of attempts and the cannulation time, and incidence of complications.
    Results: Two hundred eighty-five patients were statistically analyzed. The success rate of first attempt was 91.6% in the M-LAINUT group (n = 143) and 57.7% in the C-PT group (n = 142; P < .001) (odds ratio, 7.9; 95% confidence interval, 4.0-15.7). The total success rate (≤5 minutes and ≤3 attempts) in the M-LAINUT group was 97.9%, compared to 84.5% in the palpation group (P < .001) (odds ratio, 8.5; 95% confidence interval, 2.5-29.2). The total cannulation time was shorter and the number of attempts was fewer in the M-LAINUT group than that in the C-PT group (P < .05). The incidence of hematoma in the C-PT group was 19.7%, which was significantly higher than the 2.8% in the M-LAINUT group (P < .001).
    Conclusions: Modified long-axis in-plane ultrasound-guided radial artery cannulation can increase the first and total radial artery cannulation success rates, reduce the number of attempts, and shorten the total cannulation time in adults.
    MeSH term(s) Aged ; Anesthesiologists ; Catheterization, Peripheral/methods ; Elective Surgical Procedures ; Female ; Humans ; Male ; Middle Aged ; Palpation/methods ; Prospective Studies ; Radial Artery ; Ultrasonography, Interventional/methods
    Language English
    Publishing date 2020-01-08
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000018747
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    Ua VI Zs.171: Show issues Location:
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  6. Article: [The opportune time and implication of determining serum choline esterase in acute organophosphorous poisoning].

    Qian, De-cai / Huang, Ming-kang / Tian, Yun / Zhang, Jin / Huang, Qi-jian / Wang, Qiang

    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue

    2007  Volume 19, Issue 12, Page(s) 738

    MeSH term(s) Acute Disease ; Adolescent ; Adult ; Aged ; Cholinesterases/blood ; Female ; Humans ; Male ; Middle Aged ; Organophosphate Poisoning ; Poisoning/enzymology ; Time Factors ; Young Adult
    Chemical Substances Cholinesterases (EC 3.1.1.8)
    Language Chinese
    Publishing date 2007-12
    Publishing country China
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1003-0603
    ISSN 1003-0603
    Database MEDical Literature Analysis and Retrieval System OnLINE

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