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  1. Book: Precision medicine

    Huang, Tao

    (Methods in molecular biology ; 2204 ; Springer protocols)

    2020  

    Author's details edited by Tao Huang
    Series title Methods in molecular biology ; 2204
    Springer protocols
    Collection
    Language English
    Size xi, 226 Seiten, Illustrationen
    Publisher Humana Press
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT020551262
    ISBN 978-1-0716-0903-3 ; 9781071609040 ; 1-0716-0903-3 ; 1071609041
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 7042 -2204- verfügbar in Königswinter Königswinter

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  2. Book: Liquid biopsies

    Huang, Tao / Yang, Jialiang / Tian, Geng

    methods and protocols

    (Methods in molecular biology ; 2695 ; Springer protocols)

    2023  

    Author's details edited by Tao Huang, Jialiang Yang, Geng Tian
    Series title Methods in molecular biology ; 2695
    Springer protocols
    Collection
    Keywords Biopsy ; Cancer/Diagnosis
    Subject code 616.0758
    Language English
    Size xiii, 368 Seiten, Illustrationen, 26 cm
    Publisher Humana Press
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT030074171
    ISBN 978-1-0716-3345-8 ; 9781071633465 ; 1-0716-3345-7 ; 1071633465
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 7042 -2695- not available for loan Lesesaal EG

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  3. Book: Computational systems biology

    Huang, Tao

    methods and protocols

    (Methods in molecular biology ; 1754 ; Springer protocols)

    2018  

    Author's details edited by Tao Huang
    Series title Methods in molecular biology ; 1754
    Springer protocols
    Collection
    Keywords Cancer Cell Line Encyclopedia ; Genotype-Tissue Expression ; Python ; RNA-sequencing ; Chip-Seq
    Subject code 570
    Language English
    Size xii, 417 Seiten, Illustrationen, 25.4 cm x 17.8 cm
    Publisher Humana Press
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT019629196
    ISBN 978-1-4939-7716-1 ; 1-4939-7716-4 ; 9781493977178 ; 1493977172
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 7042 -1754- verfügbar in Königswinter Königswinter

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  4. Book ; Online: Advanced Interpretable Machine Learning Methods for Clinical NGS Big Data of Complex Hereditary Diseases

    Cai, Yudong / Huang, Tao / Jia, Peilin

    2020  

    Keywords Science: general issues ; Medical genetics ; artificial intelligence ; NGS - next generation sequencing ; non-invasive prenatal testing (NIPT) ; WGS - whole-genome sequencing ; WES - whole-exome sequencing
    Size 1 electronic resource (234 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230444
    ISBN 9782889662746 ; 2889662748
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Book ; Online: Machine Learning Advanced Dynamic Omics Data Analysis for Precision Medicine

    Zeng, Tao / Huang, Tao / Lu, Chuan

    2020  

    Keywords Science: general issues ; Medical genetics ; machine learning ; dynamic ; OMICS data ; precision medicine ; integration
    Size 1 electronic resource (393 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021231186
    ISBN 9782889635542 ; 2889635546
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Book ; Online: Security and Privacy for Modern Wireless Communication Systems

    Huang, Tao / Yan, Shihao / Zhang, Guanglin / Sun, Li / Yuen, Tsz Hon / Park, YoHan / Lee, Changhoon

    2023  

    Keywords Information technology industries ; Computer science ; propagation trends ; social networks ; group features ; dilated CNN ; machine learning ; physical layer security ; Rice channels ; wireless communications ; 6G security ; sycon ; cube attack ; state recovery ; wireless body area networks ; authentication ; biometric ; physical unclonable function ; BAN logic ; RoR model ; AVISPA ; 6G wireless communications ; chi-square ; cybersecurity ; intrusion detection system ; machine learning techniques ; meta-model ; stacking ensemble learning ; voting techniques ; fault attack ; error detection ; code abiding ; overcost ; bitslice cipher ; multiple eavesdroppers ; full-duplex ; underground mine ; amplify-and-forward relay ; communication system security ; physical layer ; wireless communication ; precoding ; wire-tap channel ; blockchain ; wireless communication network ; malicious node ; security protocol ; intrusion detection ; in-vehicle communication ; inter-vehicle communication ; optical communication ; security wireless ; visible light communication ; wireless optical communication ; convolutional neural network ; CNN ; counterfeit detection ; device fingerprinting ; distinct native attribute (DNA) ; information and communications technology ; multiple discriminant analysis ; MDA ; WirelessHART ; wireless communications security ; digital twin ; Internet of Things ; healthcare ; encryption ; privacy ; rural ; LPWAN ; secure localization ; positioning ; distance vector hop ; DV-Hop ; security attacks ; wireless sensor network ; security ; steganalysis ; covert channel ; steganography ; undetectability ; aggregator-based grouping ; wireless sensor networks ; encryption and decryption operations
    Language English
    Size 1 electronic resource (308 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030382140
    ISBN 9783036582290 ; 3036582290
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  7. Article ; Online: "Listening Between the Lines": Soundscapes in Yusef Komunyakaa's Poetry.

    Huang, Tao

    Journal of psycholinguistic research

    2023  Volume 52, Issue 6, Page(s) 1939–1956

    Abstract: Yusef Komunyakaa's poetry is widely acclaimed for its sui generis soundscapes, which shows the poet's highly sensitive auditory perception in his literary creations. Soundscapes, in his poetry, play a pivotal role in revealing social malaise-racial ... ...

    Abstract Yusef Komunyakaa's poetry is widely acclaimed for its sui generis soundscapes, which shows the poet's highly sensitive auditory perception in his literary creations. Soundscapes, in his poetry, play a pivotal role in revealing social malaise-racial inequalities and gender-biased black relations-in the multiracial US. This article thus explores race- and gender-related societal problems mirrored in Komunyakaa's poetry through the prism of soundscapes. It first aims to examine how soundscapes are presented between poetic lines as a culture carrier, and then investigates the disciplinary power and oppositional function of soundscapes. Combining textual close reading with interdisciplinary research methodology, this article brings to light the complexity and specificity of soundscapes in Komunyakaa's poetry. For one thing, the soundscape constructed by the privileged serves as an oppressive force to discipline the disempowered groups; for another, the soundscape the underprivileged produce is utilized as an instrument of resistance and healing, offering them a sonic weapon to deconstruct the oppressive sound imperialism as well as construct the affective community of African Americans. This study not only adds to the research on Komunyakaa's poetry by offering a renewed viewpoint of excavating this poet and his political proposition of equality and equity, but also attracts academic attention to the role of literary soundscape in Afro-American literature in revealing the long-standing societal problems in the US.
    MeSH term(s) Humans ; Sound ; Interpersonal Relations ; Literature, Modern
    Language English
    Publishing date 2023-06-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 124517-x
    ISSN 1573-6555 ; 0090-6905
    ISSN (online) 1573-6555
    ISSN 0090-6905
    DOI 10.1007/s10936-023-09978-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1111: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: TRPV1 is a potential biomarker for the prediction and treatment of multiple cancers based on a pan-cancer analysis.

    Huang, Tao

    Mathematical biosciences and engineering : MBE

    2022  Volume 19, Issue 8, Page(s) 8361–8379

    Abstract: Background: Transient receptor potential cation channel subfamily V member 1 (TRPV1) was considered to play pivotal roles in multiple cancers; however, the expression and clinical significance of the TRPV1 remain unclear, which were explored in this ... ...

    Abstract Background: Transient receptor potential cation channel subfamily V member 1 (TRPV1) was considered to play pivotal roles in multiple cancers; however, the expression and clinical significance of the TRPV1 remain unclear, which were explored in this study.
    Results: The pan-cancer analysis was performed based on 10,236 samples in 32 cancers. Differential TRPV1 expression levels were detected in 12 cancers (p < 0.05). TRPV1 demonstrated its conspicuous prognosis significance and prediction effects for some cancers (e.g., lung adenocarcinoma), indicating its potential as a valuable and novel biomarker in treating and predicting cancers. TRPV1 expression was relevant to DNA methyltransferases, mismatch repair genes, tumor mutational burden, and microsatellite instability. TRPV1 expression was associated with the immune microenvironment of some cancers, and its roles in different cancers may be mediated by affecting various immune cells. Gene set enrichment analysis discloses the significant relevance of TRPV1 expression with a series of metabolic and immunoregulatory-related pathways.
    Conclusions: This study provided a comprehensive workflow of the expression, clinical significance, and underlying mechanisms of TRPV1 in pan-cancer. TRPV1 may be an underlying biomarker for predicting and treating multiple cancer.
    MeSH term(s) Adenocarcinoma of Lung ; Animals ; Biomarkers, Tumor/genetics ; Disease Models, Animal ; Lung Neoplasms/diagnosis ; Lung Neoplasms/genetics ; Lung Neoplasms/therapy ; TRPV Cation Channels/genetics ; TRPV Cation Channels/metabolism ; Tumor Microenvironment
    Chemical Substances Biomarkers, Tumor ; TRPV Cation Channels
    Language English
    Publishing date 2022-07-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2265126-3
    ISSN 1551-0018 ; 1551-0018
    ISSN (online) 1551-0018
    ISSN 1551-0018
    DOI 10.3934/mbe.2022389
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The Therapeutic Targets Revealed by Integrative Network Analysis of Noncoding RNAs.

    Huang, Tao

    Current gene therapy

    2021  Volume 21, Issue 4, Page(s) 279

    MeSH term(s) Gene Regulatory Networks ; RNA, Long Noncoding/genetics
    Chemical Substances RNA, Long Noncoding
    Language English
    Publishing date 2021-10-21
    Publishing country United Arab Emirates
    Document type Editorial
    ZDB-ID 2146187-9
    ISSN 1875-5631 ; 1566-5232
    ISSN (online) 1875-5631
    ISSN 1566-5232
    DOI 10.2174/156652322104211018103532
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5883: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Biological functions of PCAT-1/ SOX4 in cell proliferation and invasion of breast cancer.

    Huang, Tao / Zhang, Jizong

    Cellular and molecular biology (Noisy-le-Grand, France)

    2024  Volume 70, Issue 4, Page(s) 90–94

    Abstract: Breast cancer (BC) is one of the most common fatal cancers. Recent studies have identified the vital role of long noncoding RNA (lncRNAs) in the development and progression of BC. In this research, lncRNA PCAT-1 was studied to identify how it functioned ... ...

    Abstract Breast cancer (BC) is one of the most common fatal cancers. Recent studies have identified the vital role of long noncoding RNA (lncRNAs) in the development and progression of BC. In this research, lncRNA PCAT-1 was studied to identify how it functioned in the metastasis of BC. PCAT-1 expression of tissues was detected by real-time quantitative polymerase chain reaction (RT-qPCR) in 50 BC patients. Cell proliferation, wound healing assay and transwell assay were used to observe the biological behavior changes of BC cells through knockdown or overexpression of PCAT-1. In addition, RT-qPCR and Western blot assay were performed to discover the potential target protein of PCAT-1 in BC. PCAT-1 expression level in BC samples was higher than that of adjacent ones. Besides, cell proliferation, migrated ability and cell invaded ability of BC cells were inhibited after PCAT-1 was silenced. Cell proliferation, migration and invasion of BC cells were promoted after PCAT-1 was overexpressed. In addition, SOX4 was downregulated after silence of PCAT-1 in BC cells, while SOX4 was upregulated after overexpression of PCAT-1 in BC cells. Furthermore, SOX4 was upregulated in BC tissues and was positively associated with PCAT-1. Our study uncovers a new oncogene in BC and suggests that PCAT-1 could enhance BC cell proliferation, migration and invasion via targeting SOX4, which provided a novel therapeutic target for BC patients.
    MeSH term(s) Humans ; Cell Proliferation/genetics ; SOXC Transcription Factors/metabolism ; SOXC Transcription Factors/genetics ; Female ; Breast Neoplasms/pathology ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Cell Movement/genetics ; Neoplasm Invasiveness ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Middle Aged
    Chemical Substances SOXC Transcription Factors ; RNA, Long Noncoding ; SOX4 protein, human ; PCAT-1 lncRNA, human
    Language English
    Publishing date 2024-04-28
    Publishing country France
    Document type Journal Article
    ZDB-ID 1161779-2
    ISSN 1165-158X ; 0145-5680
    ISSN (online) 1165-158X
    ISSN 0145-5680
    DOI 10.14715/cmb/2024.70.4.14
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3812: Show issues Location:
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