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  1. Article ; Online: Transparent tissue in solid state for solvent-free and antifade 3D imaging.

    Hsiao, Fu-Ting / Chien, Hung-Jen / Chou, Ya-Hsien / Peng, Shih-Jung / Chung, Mei-Hsin / Huang, Tzu-Hui / Lo, Li-Wen / Shen, Chia-Ning / Chang, Hsiu-Pi / Lee, Chih-Yuan / Chen, Chien-Chia / Jeng, Yung-Ming / Tien, Yu-Wen / Tang, Shiue-Cheng

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 3395

    Abstract: Optical clearing with high-refractive-index (high-n) reagents is essential for 3D tissue imaging. However, the current liquid-based clearing condition and dye environment suffer from solvent evaporation and photobleaching, causing difficulties in ... ...

    Abstract Optical clearing with high-refractive-index (high-n) reagents is essential for 3D tissue imaging. However, the current liquid-based clearing condition and dye environment suffer from solvent evaporation and photobleaching, causing difficulties in maintaining the tissue optical and fluorescent features. Here, using the Gladstone-Dale equation [(n-1)/density=constant] as a design concept, we develop a solid (solvent-free) high-n acrylamide-based copolymer to embed mouse and human tissues for clearing and imaging. In the solid state, the fluorescent dye-labeled tissue matrices are filled and packed with the high-n copolymer, minimizing scattering in in-depth imaging and dye fading. This transparent, liquid-free condition provides a friendly tissue and cellular environment to facilitate high/super-resolution 3D imaging, preservation, transfer, and sharing among laboratories to investigate the morphologies of interest in experimental and clinical conditions.
    MeSH term(s) Mice ; Humans ; Animals ; Imaging, Three-Dimensional/methods ; Solvents ; Fluorescent Dyes ; Acrylamide ; Optical Imaging
    Chemical Substances Solvents ; Fluorescent Dyes ; Acrylamide (20R035KLCI)
    Language English
    Publishing date 2023-06-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-39082-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: H-reflex in abductor hallucis and postural performance between flexible flatfoot and normal foot.

    Huang, Tzu-Hui / Chou, Li-Wei / Huang, Cheng-Ya / Wei, Shun-Wa / Tsai, Yi-Ju / Chen, Yu-Jen

    Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine

    2019  Volume 37, Page(s) 27–33

    Abstract: Objective: Morphological changes of the abductor hallucis muscle (AbH) in flexible flatfoot (FF) individuals influence regulations of the medial longitudinal arch (MLA). Prolonged and repeated stretching of AbH in flexible flatfoot may cause changes in ... ...

    Abstract Objective: Morphological changes of the abductor hallucis muscle (AbH) in flexible flatfoot (FF) individuals influence regulations of the medial longitudinal arch (MLA). Prolonged and repeated stretching of AbH in flexible flatfoot may cause changes in muscle reflex properties and further influence postural performance. However, AbH muscle reflex under different postural conditions have never been examined. The purpose of this study was to investigate differences in AbH H-reflex and postural performance between individuals with normal foot (NF) alignment and FF under prone, double-leg stance (DLS), and single-leg stance (SLS) conditions.
    Design: Cross-sectional study.
    Setting: University laboratory.
    Participants: Individuals with FF (n = 12) and NF (n = 12).
    Main outcome measures: AbH H-reflex, AbH EMG and center of pressure (CoP) displacement.
    Results: Under all postural conditions, AbH H-reflex was significantly lower in the FF group (P < .05). Under the SLS condition, AbH EMG was significantly higher in the FF group (P < .05), and CoP displacement for the medial-lateral and anterior-posterior directions were significantly higher in the FF group (P < .05).
    Conclusions: With increased postural demand, FF individuals maintained their postural stability by recruiting greater AbH activities than through automatic stretch reflex, but FF individuals still showed inferior posture stability.
    MeSH term(s) Adult ; Case-Control Studies ; Cross-Sectional Studies ; Electromyography ; Female ; Flatfoot/physiopathology ; H-Reflex/physiology ; Humans ; Male ; Muscle, Skeletal/physiopathology ; Postural Balance/physiology
    Language English
    Publishing date 2019-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2008604-0
    ISSN 1873-1600 ; 1466-853X
    ISSN (online) 1873-1600
    ISSN 1466-853X
    DOI 10.1016/j.ptsp.2019.02.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5218: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: The association between premenstrual dysphoric disorder and internet use disorder.

    Ko, Chih-Hung / Yen, Cheng-Fang / Long, Cheng-Yu / Chen, Cheng-Sheng / Huang, Tzu-Hui / Yen, Ju-Yu

    Women & health

    2014  Volume 54, Issue 3, Page(s) 245–261

    Abstract: Premenstrual dysphoric disorder (PMDD) is an important women's mental health issue. This study aimed to investigate the association between Internet use disorder (IUD), PMDD, and their associated factors, such as stress and impulsivity. Women with PMDD ( ... ...

    Abstract Premenstrual dysphoric disorder (PMDD) is an important women's mental health issue. This study aimed to investigate the association between Internet use disorder (IUD), PMDD, and their associated factors, such as stress and impulsivity. Women with PMDD (n = 79) and controls (n = 76) were recruited from the community. The diagnoses of PMDD and IUD were confirmed by psychiatric interviews. Participants were evaluated with the Chen Internet Addiction Scale, Perceived Stress Scale, and Barratt Impulsiveness Scale in both the premenstrual and follicular phases. Women with PMDD were more likely to have IUD. Women with PMDD had greater severity of IUD, perceived stress, and impulsivity than the control group in the premenstrual phase. Impulsivity mediated the association between PMDD and IUD, while both impulsivity and perceived stress mediated the association between PMDD and IUD severity. Thus, IUD should be evaluated and treated among women with PMDD, particularly for those with higher impulsivity or higher perceived stress. Strategies for stress management and counseling for impulsivity should be provided to women with PMDD, particular to those comorbid with IUD.
    MeSH term(s) Adolescent ; Adult ; Behavior, Addictive/diagnosis ; Behavior, Addictive/psychology ; Case-Control Studies ; Female ; Humans ; Impulsive Behavior/psychology ; Internet/utilization ; Interview, Psychological ; Logistic Models ; Premenstrual Syndrome/psychology ; Psychiatric Status Rating Scales ; Severity of Illness Index ; Socioeconomic Factors ; Stress, Psychological/psychology ; Young Adult
    Language English
    Publishing date 2014
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603396-9
    ISSN 1541-0331 ; 0363-0242
    ISSN (online) 1541-0331
    ISSN 0363-0242
    DOI 10.1080/03630242.2014.883661
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2265: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  4. Article: Depression, irritability, and anxiety in women with premenstrual dysphoric disorder.

    Ko, Chih-Hung / Long, Cheng-Yu / Chen, Su-Yin / Chen, I-Ju / Huang, Tzu-Hui / Yen, Ju-Yu

    International journal of psychiatry in medicine

    2013  Volume 46, Issue 1, Page(s) 39–55

    Abstract: Objective: Depression, anxiety, and irritability are the three most studied symptoms of premenstrual dysphoric disorder (PMDD). This study aimed to assess the premenstrual exacerbation of these symptoms and their role in the diagnosis or functional ... ...

    Abstract Objective: Depression, anxiety, and irritability are the three most studied symptoms of premenstrual dysphoric disorder (PMDD). This study aimed to assess the premenstrual exacerbation of these symptoms and their role in the diagnosis or functional impairment of PMDD.
    Methods: We recruited women with PMDD not undergoing any treatment and control subjects from the community. The diagnosis of PMDD was based on a positive score on the Premenstrual Symptoms Screening Tool and confirmed by psychiatric interviews and questionnaire follow-up for three menstrual cycles. A total of 67 women with PMDD and 75 control subjects participated the survey and reach the final analysis. They complete the Center for Epidemiological Studies, the Chinese Version of the Buss-Durkee Hostility Inventory-Short Form, and the Penn State Worry Questionnaire in both the premenstrual and follicular phases.
    Results: Women with PMDD, but no controls, demonstrate the premenstrual exacerbation of these three symptoms. Depression was the most prominent feature of the PMDD diagnosis while irritability was most frequently associated with functional impairment.
    Conclusions: Depression and irritability should be properly evaluated and treated among women with PMDD.
    MeSH term(s) Adult ; Anxiety/diagnosis ; Anxiety/epidemiology ; Comorbidity ; Depression/diagnosis ; Depression/epidemiology ; Female ; Humans ; Irritable Mood/physiology ; Premenstrual Syndrome/diagnosis ; Premenstrual Syndrome/epidemiology ; Prospective Studies ; Young Adult
    Language English
    Publishing date 2013
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 220669-9
    ISSN 1541-3527 ; 0091-2174
    ISSN (online) 1541-3527
    ISSN 0091-2174
    DOI 10.2190/PM.46.1.d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 641: Show issues Location:
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  5. Article: Cue-induced positive motivational implicit response in young adults with Internet gaming addiction.

    Yen, Ju-Yu / Yen, Cheng-Fang / Chen, Cheng-Sheng / Tang, Tze-Chun / Huang, Tzu-Hui / Ko, Chih-Hung

    Psychiatry research

    2011  Volume 190, Issue 2-3, Page(s) 282–286

    Abstract: This study evaluated the positive motivational implicit response to Internet gaming cues (i.e., screenshots of popular online games) to identify potential mechanisms of dyscontrolled Internet use in young adults with Internet gaming addiction (IGA). The ... ...

    Abstract This study evaluated the positive motivational implicit response to Internet gaming cues (i.e., screenshots of popular online games) to identify potential mechanisms of dyscontrolled Internet use in young adults with Internet gaming addiction (IGA). The final analysis included 64 young adults with IGA and 71 control subjects. The subjects completed the implicit association task to test their reaction to congruent pairing (Internet gaming screenshot paired with liked words) and incongruent pairing (Internet gaming screenshot paired with disliked words). The results demonstrated that, compared to the control group, the IGA group reacted faster to congruent pairing. It suggests that the IGA group had a positive motivational implicit response to screenshots of online games. Implicit cognition is an important mechanism of dyscontrolled substance use, such as alcohol dependence. This result suggests that implicit cognition might also be associated with dyscontrolled online gaming. The findings also demonstrate the important role of implicit cognition in dyscontrolled Internet use in young adults with IGA.
    MeSH term(s) Adult ; Analysis of Variance ; Cognition Disorders/diagnosis ; Cognition Disorders/etiology ; Cues ; Female ; Gambling/complications ; Gambling/psychology ; Humans ; Internet ; Male ; Motivation/physiology ; Neuropsychological Tests ; Psychiatric Status Rating Scales ; Retrospective Studies ; Surveys and Questionnaires ; Young Adult
    Language English
    Publishing date 2011-12-30
    Publishing country Ireland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 445361-x
    ISSN 1872-7123 ; 1872-7506 ; 0165-1781 ; 0925-4927
    ISSN (online) 1872-7123 ; 1872-7506
    ISSN 0165-1781 ; 0925-4927
    DOI 10.1016/j.psychres.2011.07.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1541: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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