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Article: Corrigendum: Case report: Abruptio placentae and epileptic seizure after occurrence of perinatal hyperglycaemia in woman with gestational diabetes mellitus and hypertriglyceridemia-induced acute pancreatitis.

He, Yanlang / Huang, Zhijie / Wei, Changli / Chen, Jianyong

2023 Volume 14, Page(s) 1343681

Abstract: This corrects the article DOI: 10.3389/fendo.2023.1220957.]. ...

Abstract	[This corrects the article DOI: 10.3389/fendo.2023.1220957.].
Language	English
Publishing date	2023-12-14
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	2592084-4
ISSN	1664-2392
ISSN	1664-2392
DOI	10.3389/fendo.2023.1343681
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Article: Case Report: Abruptio placentae and epileptic seizure after occurrence of perinatal hyperglycaemia in woman with gestational diabetes mellitus and hypertriglyceridemia-induced acute pancreatitis.

He, Yanlang / Huang, Zhijie / Wei, Changli / Chen, Jianyong

Frontiers in endocrinology

2023 Volume 14, Page(s) 1220957

Abstract: Hypertriglyceridemia-induced acute pancreatitis seldom occurs in the second trimester of pregnancy with gestational diabetes mellitus. For these patients, the existing knowledge on concomitant hyperglycemia is not sufficient. We report a case of abruptio ...

Abstract	Hypertriglyceridemia-induced acute pancreatitis seldom occurs in the second trimester of pregnancy with gestational diabetes mellitus. For these patients, the existing knowledge on concomitant hyperglycemia is not sufficient. We report a case of abruptio placentae and epileptic seizure following perinatal hyperglycaemia in woman with gestational diabetes mellitus and hypertriglyceridemia-induced acute pancreatitis. The occurrence of abruptio placentae and epileptic seizure may be associated with concomitant hyperglycemia, and the epileptic seizure was terminated after she underwent treatment with insulin. We should pay more attention to the adverse effects of perinatal hyperglycemia and continue to give appropriate insulin treatment even if patients have passed the acute phase of hypertriglyceridemia-induced acute pancreatitis.
MeSH term(s)	Pregnancy ; Female ; Humans ; Abruptio Placentae/etiology ; Diabetes, Gestational ; Hyperglycemia/complications ; Acute Disease ; Pancreatitis/complications ; Seizures ; Hypertriglyceridemia/complications ; Epilepsy/complications ; Insulin
Chemical Substances	Insulin
Language	English
Publishing date	2023-10-18
Publishing country	Switzerland
Document type	Case Reports ; Research Support, Non-U.S. Gov't
ZDB-ID	2592084-4
ISSN	1664-2392
ISSN	1664-2392
DOI	10.3389/fendo.2023.1220957
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Article ; Online: Wheat gluten deamidation: structure, allergenicity and its application in hypoallergenic noodles.

Liu, Mingxi / Dai, Shuhan / Yin, Lijun / Huang, Zhijie / Jia, Xin

Journal of the science of food and agriculture

2023 Volume 104, Issue 4, Page(s) 2477–2483

Abstract: Background: Wheat gluten (WG) containing gliadin and glutenin are considered the main allergens in wheat allergy as a result of their glutamine-rich peptides. Deamidation is a viable and efficient approach for protein modifications converting glutamine ... ...

Abstract	Background: Wheat gluten (WG) containing gliadin and glutenin are considered the main allergens in wheat allergy as a result of their glutamine-rich peptides. Deamidation is a viable and efficient approach for protein modifications converting glutamine into glutamic acid, which may have the potential for allergenicity reduction of WG. Results: Deamidation by citric acid was performed to investigate the effects on structure, allergenicity and noodle textural properties of wheat gluten (WG). WG was heated at 100 °C in 1 m citric acid to yield deamidated WG with degrees of deamidation (DD) ranging from DWG-25 (25% DD) to DWG-70 (70% DD). Fourier-transform infrared and intrinsic fluorescence spectroscopy results suggested the unfolding of WG structure during deamidation, and sodium dodecyl sulphate-polyacrylamide gel electrophoresis showed molecular weight shifts at the 35-63 kDa region, suggesting that the deamidation mainly occurred on low molecular weight glutenin subunits and γ- gliadin of the WG. An enzyme-linked immunosorbent assay of deamidated WG revealed a decrease in absorbance and immunoblotting indicated that the intensities of protein bands at 35-63 kDa decreased, which suggested that deamidation of WG might have caused a greater loss of epitopes than the generation of new epitopes caused by unfolding of WG, and thereby reduction of the immunodominant immunoglobulin E binding capacity, ultimately leading to the decrease in allergenicity. DWG-25 was used in the preparation of recombinant hypoallergenic noodles, and the hardness, elasticity, chewiness and gumminess were improved significantly by the addition of azodicarbonamide. Conclusion: The present shows the potential for deamidation of the WG products used in novel hypoallergenic food development. © 2023 Society of Chemical Industry.
MeSH term(s)	Humans ; Gliadin ; Allergens/chemistry ; Glutamine ; Glutens/chemistry ; Wheat Hypersensitivity ; Epitopes/chemistry ; Citric Acid
Chemical Substances	Gliadin (9007-90-3) ; Allergens ; Glutamine (0RH81L854J) ; Glutens (8002-80-0) ; Epitopes ; Citric Acid (2968PHW8QP)
Language	English
Publishing date	2023-11-28
Publishing country	England
Document type	Journal Article
ZDB-ID	184116-6
ISSN	1097-0010 ; 0022-5142
ISSN (online)	1097-0010
ISSN	0022-5142
DOI	10.1002/jsfa.13133
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Article: [Notch signaling regulates macrophages during inflammation and infection: An update].

Chen, Chuxi / Liu, Qiaoyuan / Huang, Zhijie / Ning, Yunshan / Li, Yan

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology

2023 Volume 39, Issue 5, Page(s) 468–473

Abstract: Macrophage as a crucial component of innate immunity, plays an important role in inflammation and infection immunity. Notch signal pathway is a highly conserved pathway, which regulates cellular fate and participates in numerous pathological processes. ... ...

Abstract	Macrophage as a crucial component of innate immunity, plays an important role in inflammation and infection immunity. Notch signal pathway is a highly conserved pathway, which regulates cellular fate and participates in numerous pathological processes. At present, a lot of literature has confirmed the role of Notch signaling in regulating the differentiation, activation and metabolism of macrophage during inflammation and infection. This review focuses on how Notch signaling promotes macrophage pro-inflammatory and anti-infective immune function in different inflammatory and infectious diseases. In this regulation, Notch signaling interact with TLR signaling in macrophages or inflammatory-related cytokines including IL-6, IL-12, and TNF-α. Additionally, the potential application and challenges of Notch signaling as a therapeutic target against inflammation and infectious diseases are also discussed.
MeSH term(s)	Humans ; Signal Transduction ; Macrophages ; Cytokines/metabolism ; Inflammation/metabolism ; Communicable Diseases ; Receptors, Notch/metabolism
Chemical Substances	Cytokines ; Receptors, Notch
Language	Chinese
Publishing date	2023-05-30
Publishing country	China
Document type	Review ; English Abstract ; Journal Article
ISSN	1007-8738
ISSN	1007-8738
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Article ; Online: Experimental dosimetry of EDR2 films in scanning carbon-ion irradiation.

Wang, Weiwei / Deng, Yu / Huang, Zhijie

Journal of applied clinical medical physics

2022 Volume 23, Issue 7, Page(s) e13636

Abstract: Purpose: To investigate the dose-sensitometric response of extended dose range (EDR2) films to scanning carbon-ion beams and to evaluate the applications of the obtained response curves to carbon-ion dose distributions.: Methods: EDR2 films were ... ...

Abstract	Purpose: To investigate the dose-sensitometric response of extended dose range (EDR2) films to scanning carbon-ion beams and to evaluate the applications of the obtained response curves to carbon-ion dose distributions. Methods: EDR2 films were irradiated by mono-energetic scanning carbon-ion beams with different doses to obtain sensitometric curves at different integrated depth doses (DDDs). Six different DDDs were generated by using a proper buildup for each mono-energetic beam and were used to investigate the energy dependence. The sensitometric curves were obtained by fitting the net optical density (netOD) to dose at different DDDs. The dose difference between the value converted from the netOD and that calculated in the treatment planning system (TPS) was investigated to evaluate the application scope of the sensitometric curve. Results: Digitizing the EDR2 film with a resolution of 0.36 (72 dpi) provided a good signal-to-noise ratio, and the sensitometric curve was linear at all DDDs of clinically relevant incident kinetic energies in the netOD range of 0.02-1.70 for carbon-ion film dosimetry. The factors used to convert the netOD to absorbed dose were expressed as a linear function of DDDs, with which the depth dose difference between converted and TPS was less than 3% in the proximal area for incident kinetic energies lower than 307.5 MeV/u. Conclusion: The EDR2 film is a feasible tool for scanning carbon-ion beam profile measurements by directly evaluating the netOD distribution with proper digitizing resolution and netOD range. By applying the conversion factors, the EDR2 film can also be employed to perform the percentage depth dose consistency checking and linear energy transfer comparison of carbon-ion lower than 307.5 MeV/u.
MeSH term(s)	Carbon ; Film Dosimetry ; Humans ; Radiometry ; Reproducibility of Results ; Sensitivity and Specificity
Chemical Substances	Carbon (7440-44-0)
Language	English
Publishing date	2022-05-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	2010347-5
ISSN	1526-9914 ; 1526-9914
ISSN (online)	1526-9914
ISSN	1526-9914
DOI	10.1002/acm2.13636
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Article ; Online: Recent advances in soybean protein processing technologies: A review of preparation, alterations in the conformational and functional properties

Huang, Zhijie / Qu, Yuanyuan / Hua, Xiaohan / Wang, Fengzhong / Jia, Xin / Yin, Lijun

International Journal of Biological Macromolecules. 2023 July 17, p.125862-

2023 , Page(s) 125862–

Abstract: Currently, growing concerns about sustainable development and health awareness have driven the development of plant-based meat substitutes. Soybean proteins (SPs) are eco-friendly and high-quality food sources with well-balanced amino acids to meet ... ...

Abstract	Currently, growing concerns about sustainable development and health awareness have driven the development of plant-based meat substitutes. Soybean proteins (SPs) are eco-friendly and high-quality food sources with well-balanced amino acids to meet consumer demand. The functionality and physicochemical attributes of SPs can be improved by appropriate processing and modification. With the burgeoning advances of modern processing technologies in the food industry, a multitude of functional foods and ingredients can be manufactured based on SPs. This review mainly highlights the conformational changes of SPs under traditional and emerging processing technologies and the resultant functionality modifications. By elucidating the relationship between processing-induced structural and functional alterations, detailed and systematic insights are provided regarding the exploitation of these techniques to develop different nutritional and functional soybean products. Some popular methods to modify SPs properties are discussed in this paper, including thermal treatment, fermentation, enzyme catalysis, high hydrostatic pressure, high-intensity ultrasound, atmospheric cold plasma, high-moisture extrusion, glycosylation, pulsed ultraviolet light and interaction with polyphenols. Given these processing technologies, it is promising to expand the application market for SPs and boost the advancement of the soybean industry.
Keywords	catalytic activity ; consumer demand ; enzymes ; extrusion ; fermentation ; food industry ; glycosylation ; heat treatment ; high pressure treatment ; markets ; meat ; nonthermal processing ; polyphenols ; soy protein ; soybeans ; sustainable development ; ultrasonics ; ultraviolet radiation ; Soybean proteins ; Processing technologies ; Functionality ; Conformational changes ; Industrial applications
Language	English
Dates of publication	2023-0717
Publishing place	Elsevier B.V.
Document type	Article ; Online
Note	Pre-press version
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2023.125862
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Structural basis of antiphage immunity generated by a prokaryotic Argonaute-associated SPARSA system.

Zhen, Xiangkai / Xu, Xiaolong / Ye, Le / Xie, Song / Huang, Zhijie / Yang, Sheng / Wang, Yanhui / Li, Jinyu / Long, Feng / Ouyang, Songying

Nature communications

2024 Volume 15, Issue 1, Page(s) 450

Abstract: Argonaute (Ago) proteins are ubiquitous across all kingdoms of life. Eukaryotic Agos (eAgos) use small RNAs to recognize transcripts for RNA silencing in eukaryotes. In contrast, the functions of prokaryotic counterparts (pAgo) are less well known. ... ...

Abstract	Argonaute (Ago) proteins are ubiquitous across all kingdoms of life. Eukaryotic Agos (eAgos) use small RNAs to recognize transcripts for RNA silencing in eukaryotes. In contrast, the functions of prokaryotic counterparts (pAgo) are less well known. Recently, short pAgos in conjunction with the associated TIR or Sir2 (SPARTA or SPARSA) were found to serve as antiviral systems to combat phage infections. Herein, we present the cryo-EM structures of nicotinamide adenine dinucleotide (NAD
MeSH term(s)	NAD ; RNA, Guide, CRISPR-Cas Systems ; Argonaute Proteins/genetics ; Bacteriophages/genetics ; Nucleic Acids
Chemical Substances	NAD (0U46U6E8UK) ; RNA, Guide, CRISPR-Cas Systems ; Argonaute Proteins ; Nucleic Acids
Language	English
Publishing date	2024-01-11
Publishing country	England
Document type	Journal Article
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-023-44660-7
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Article ; Online: Recent advances in soybean protein processing technologies: A review of preparation, alterations in the conformational and functional properties.

Huang, Zhijie / Qu, Yuanyuan / Hua, Xiaohan / Wang, Fengzhong / Jia, Xin / Yin, Lijun

International journal of biological macromolecules

2023 Volume 248, Page(s) 125862

Abstract	Currently, growing concerns about sustainable development and health awareness have driven the development of plant-based meat substitutes. Soybean proteins (SPs) are eco-friendly and high-quality food sources with well-balanced amino acids to meet consumer demand. The functionality and physicochemical attributes of SPs can be improved by appropriate processing and modification. With the burgeoning advances of modern processing technologies in the food industry, a multitude of functional foods and ingredients can be manufactured based on SPs. This review mainly highlights the conformational changes of SPs under traditional and emerging processing technologies and the resultant functionality modifications. By elucidating the relationship between processing-induced structural and functional alterations, detailed and systematic insights are provided regarding the exploitation of these techniques to develop different nutritional and functional soybean products. Some popular methods to modify SPs properties are discussed in this paper, including thermal treatment, fermentation, enzyme catalysis, high hydrostatic pressure, high-intensity ultrasound, atmospheric cold plasma, high-moisture extrusion, glycosylation, pulsed ultraviolet light and interaction with polyphenols. Given these processing technologies, it is promising to expand the application market for SPs and boost the advancement of the soybean industry.
MeSH term(s)	Food Handling/methods ; Soybean Proteins ; Glycine max ; Food Quality ; Food-Processing Industry
Chemical Substances	Soybean Proteins
Language	English
Publishing date	2023-07-17
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2023.125862
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Article: Corrigendum: C-reactive protein is an indicator of the immunosuppressive microenvironment fostered by myeloid cells in hepatocellular carcinoma.

Wang, Yongchun / Li, Zhixiong / Huang, Zhijie / Yu, Xingjuan / Zheng, Limin / Xu, Jing

Frontiers in oncology

2023 Volume 13, Page(s) 1280727

Abstract: This corrects the article DOI: 10.3389/fonc.2021.774823.]. ...

Abstract	[This corrects the article DOI: 10.3389/fonc.2021.774823.].
Language	English
Publishing date	2023-10-24
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2023.1280727
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Article: A Review on Pulsed Laser Fabrication of Nanomaterials in Liquids for (Photo)catalytic Degradation of Organic Pollutants in the Water System.

Li, Yang / Xiao, Liangfen / Zheng, Zhong / Yan, Jiujiang / Sun, Liang / Huang, Zhijie / Li, Xiangyou

Nanomaterials (Basel, Switzerland)

2023 Volume 13, Issue 19

Abstract: The water pollution caused by the release of organic pollutants has attracted remarkable attention, and solutions for wastewater treatment are being developed. In particular, the photocatalytic removal of organic pollutants in water systems is a ... ...

Abstract	The water pollution caused by the release of organic pollutants has attracted remarkable attention, and solutions for wastewater treatment are being developed. In particular, the photocatalytic removal of organic pollutants in water systems is a promising strategy to realize the self-cleaning of ecosystems under solar light irradiation. However, at present the semiconductor-based nanocatalysts can barely satisfy the industrial requirements because their wide bandgaps restrict the effective absorption of solar light, which needs an energy band modification to boost the visible light harvesting via surface engineering. As an innovative approach, pulsed laser heating in liquids has been utilized to fabricate the nanomaterials in catalysis; it demonstrates multi-controllable features, such as size, morphology, crystal structure, and even optical or electrical properties, with which photocatalytic performances can be precisely optimized. In this review, focusing on the powerful heating effect of pulsed laser irradiation in liquids, the functional nanomaterials fabricated by laser technology and their applications in the catalytic degradation of various organic pollutants are summarized. This review not only highlights the innovative works of pulsed laser-prepared nanomaterials for organic pollutant removal in water systems, such as the photocatalytic degradation of organic dyes and the catalytic reduction of toxic nitrophenol and nitrobenzene, it also critically discusses the specific challenges and outlooks of this field, including the weakness of the produced yields and the relevant automatic strategies for massive production.
Language	English
Publishing date	2023-09-23
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662255-5
ISSN	2079-4991
ISSN	2079-4991
DOI	10.3390/nano13192628
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