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  1. Article: Atrial fibrillation in a pediatric patient caused by an unusual malignant etiology: A case report.

    Hubrechts, Jelena / Vô, Christophe / Boulanger, Cécile / Carkeek, Katherine / Moniotte, Stéphane

    Frontiers in pediatrics

    2023  Volume 11, Page(s) 1051041

    Abstract: This case report describes a 15-year-old patient with a known congenital malformation syndrome and immune deficiency, presenting with new-onset atrial fibrillation (AF) after a recent diagnosis of an intrathoracic mass. Transthoracic echocardiography ... ...

    Abstract This case report describes a 15-year-old patient with a known congenital malformation syndrome and immune deficiency, presenting with new-onset atrial fibrillation (AF) after a recent diagnosis of an intrathoracic mass. Transthoracic echocardiography showed a structurally and functionally normal heart and workup confirmed a primary diffuse large B-cell lymphoma, with pericardial and left atrial involvement on cardiac magnetic resonance imaging. Electrical cardioversion was successfully performed to convert the AF and chemotherapy was promptly started. Antiarrhythmic treatment was continued for 6 weeks, without recurrent AF. We discuss the pathogenesis of AF in the setting of malignancies as well as the management strategies of AF, mainly based on adult guidelines.
    Language English
    Publishing date 2023-02-23
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2023.1051041
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  2. Article ; Online: Leftward deviation of the primary septum or dividing left atrial shelf?

    Hubrechts, Jelena / Pollenus, Julie / Gewillig, Marc

    Cardiology in the young

    2021  Volume 31, Issue 12, Page(s) 1893–1900

    Abstract: Isolated leftward prolapse or deviation of the primary atrial septum is a rare CHD that can mimic abnormal pulmonary venous return at first sight. We present a case of a newborn infant, referred for surgical correction of totally anomalous pulmonary ... ...

    Abstract Isolated leftward prolapse or deviation of the primary atrial septum is a rare CHD that can mimic abnormal pulmonary venous return at first sight. We present a case of a newborn infant, referred for surgical correction of totally anomalous pulmonary venous return into the right atrium, with the peri-operative finding of a leftward deviation of the superior margin of the primary atrial septum. The distinction with a dividing atrial shelf could not be confirmed with certainty. Fifty-three similar cases from the literature are incorporated. A detailed review of the current account on atrial septation is studied. The embryological and clinical features of a dividing partition of the left atrium are discussed.
    MeSH term(s) Atrial Septum/diagnostic imaging ; Atrial Septum/surgery ; Heart Atria/diagnostic imaging ; Heart Atria/surgery ; Heart Septal Defects, Atrial ; Humans ; Infant ; Infant, Newborn ; Pulmonary Veins ; Scimitar Syndrome
    Language English
    Publishing date 2021-11-09
    Publishing country England
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 1078466-4
    ISSN 1467-1107 ; 1047-9511
    ISSN (online) 1467-1107
    ISSN 1047-9511
    DOI 10.1017/S1047951121004418
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4050: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Direct EBUS-guided transtracheal lymphosclerosis for plastic bronchitis after Fontan.

    Hubrechts, Jelena / Dooms, Christophe / Maleux, Geert / Gewillig, Marc

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2020  Volume 97, Issue 3, Page(s) E371–E375

    Abstract: We report on a new puncture technique with direct transtracheal mediastinal lymphatic access to treat plastic bronchitis after Fontan repair. High resolution contrast-enhanced spiral CT identified enlarged lymph nodes in the paratracheal region. Inguinal ...

    Abstract We report on a new puncture technique with direct transtracheal mediastinal lymphatic access to treat plastic bronchitis after Fontan repair. High resolution contrast-enhanced spiral CT identified enlarged lymph nodes in the paratracheal region. Inguinal intranodal Gadolinium Dynamic Contrast-enhanced Magnetic Resonance lymphangiography (DCMRL) confirmed the pathologic centrifugal lymph flow passing through these lymph nodes before leaking into the bronchial tree. The abnormal hypertrophic paratracheal, subcarinal, and hilar lymph nodes were punctured with a 22G needle through an endobronchial ultrasound bronchoscope. Occlusion of the lymph vessels was obtained by injecting a mixture of lipiodol/NBCA N-butyl cyanoacrylate (Histoacryl) 5/1 under fluoroscopic control. There was a total remission of PB with now 10 months of follow-up.
    MeSH term(s) Bronchitis/diagnostic imaging ; Bronchitis/etiology ; Humans ; Lymphatic Vessels ; Lymphography ; Plastics ; Treatment Outcome
    Chemical Substances Plastics
    Language English
    Publishing date 2020-09-29
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.29284
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1226: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Article: Case Report: Disseminated Systemic Embolism of Lipiodol After Lymphography for Plastic Bronchitis After Fontan Repair.

    Hubrechts, Jelena / Wåhlander, Håkan / Kjellberg-Olofsson, Cecilia / Maleux, Geert / Gewillig, Marc

    Frontiers in pediatrics

    2020  Volume 8, Page(s) 584185

    Abstract: Lipiodol-based lymphangiography is not only a diagnostic tool for visualization of lymphatic disorders such as plastic bronchitis (PB), but also aims a therapeutic effect by embolizing lymph leakages. We performed such percutaneous lymphatic embolization ...

    Abstract Lipiodol-based lymphangiography is not only a diagnostic tool for visualization of lymphatic disorders such as plastic bronchitis (PB), but also aims a therapeutic effect by embolizing lymph leakages. We performed such percutaneous lymphatic embolization for PB in a Fontan patient with proven absence of right-to-left shunt, and demonstrated important lymphatic abnormalities in the mediastinum. Shortly after the procedure, the patient developed severe convulsive seizures, revealing multiple cerebral embolisms of Lipiodol. Radiological images were impressive, yet the clinical neurological outcome was favorable. Lipiodol-based lymphography in Fontan patients with plastic bronchitis should be avoided as this subgroup is more likely to have developed lympho-pulmonary venous connections which allow systemic emboli.
    Language English
    Publishing date 2020-10-27
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2020.584185
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  5. Article ; Online: Percutaneous obliteration of the right ventricle to avoid coronary damage by sinusoids in patients with pulmonary atresia intact ventricular septum during staged single ventricle palliation.

    Hubrechts, Jelena / Cools, Bjorn / Brown, Stephen C / Eyskens, Benedicte / Heying, Ruth / Boshoff, Derize / Gewillig, Marc

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2019  Volume 94, Issue 5, Page(s) 722–726

    Abstract: Background and aims: Suprasystemic pressure waves can damage the coronary arteries resulting in myocardial ischemia and excess early mortality. We aimed to reduce the coronary pressure wave through the sinusoids by abolishing RV volume with percutaneous ...

    Abstract Background and aims: Suprasystemic pressure waves can damage the coronary arteries resulting in myocardial ischemia and excess early mortality. We aimed to reduce the coronary pressure wave through the sinusoids by abolishing RV volume with percutaneous devices.
    Methods and results: Four patients with PA-IVS and coronary sinusoids from the hypertensive rudimentary RV were evaluated at a median age 26.6 months (range: 2.7-51.7). Right ventricle coronary dependent flow to the left ventricular myocardium was excluded. All four patients had dual perfusion with competitive flow from the RV through the sinusoids to the coronary arteries. Devices used were: Amplatzer vascular plug II of 10-16 mm; 27 coils (diameter 5-15 mm) in the oldest patient. Right ventricular angiography after cavity obliteration showed no more significant coronary perfusion through the sinusoids. There were no complications or deaths. Only minor and transient changes in the levels of troponin were observed. Coronary angiography at pre-Fontan evaluation showed no progress of coronary abnormalities in two patients.
    Conclusion: In selected patients with functionally single left ventricle, obliteration of the hypertensive RV cavity by percutaneous devices is safe and abolishes the systolic pressure wave in coronary sinusoids. When performed early, this may halt coronary damage and avoid excess mortality.
    MeSH term(s) Cardiac Catheterization/instrumentation ; Child, Preschool ; Coronary Circulation ; Coronary Vessels/physiopathology ; Heart Defects, Congenital/diagnostic imaging ; Heart Defects, Congenital/physiopathology ; Heart Defects, Congenital/therapy ; Heart Ventricles/abnormalities ; Heart Ventricles/physiopathology ; Humans ; Infant ; Palliative Care ; Pulmonary Atresia/diagnostic imaging ; Pulmonary Atresia/physiopathology ; Pulmonary Atresia/therapy ; Retrospective Studies ; Treatment Outcome ; Ventricular Function, Right ; Ventricular Pressure
    Language English
    Publishing date 2019-08-21
    Publishing country United States
    Document type Journal Article ; Video-Audio Media
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.28457
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1226: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Percutaneous embolization of lymphatic fistulae as treatment for protein-losing enteropathy and plastic bronchitis in patients with failing Fontan circulation.

    Maleux, Geert / Storme, Emma / Cools, Bjorn / Heying, Ruth / Boshoff, Derize / Louw, Jacoba J / Frerich, Stefan / Malekzadeh-Milanii, Sofie / Hubrechts, Jelena / Brown, Stephen C / Gewillig, Marc

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2019  Volume 94, Issue 7, Page(s) 996–1002

    Abstract: Background: To determine the feasibility and clinical result of selective embolization of hepatoduodenal or paratracheal lymphatics in Fontan patients with protein-losing enteropathy (PLE) or plastic bronchitis (PB).: Methods: Dilated lymph vessels ... ...

    Abstract Background: To determine the feasibility and clinical result of selective embolization of hepatoduodenal or paratracheal lymphatics in Fontan patients with protein-losing enteropathy (PLE) or plastic bronchitis (PB).
    Methods: Dilated lymph vessels in periportal (PLE) or paratracheal (PB) position were percutaneously punctured with a 22G Chiba needle. Intralymphatic position was confirmed by water soluble contrast injection with drainage to hepatoduodenal or tracheal fistulae. After flushing with 10% glucose solution, occlusion of hepatoduodenal or paratreacheal lymphatics was effected by injection of 1-4 cc mixture 4/1 of Lipiodol/n-butyl cyanoacrylate (n-BCA; Histoacryl).
    Results: Seven patients with proven PLE were treated with periportal lymphatic embolization 10.7 (range: 6.6-13.5) years after the Fontan operation. The Fontan operation was performed at a median age of 3.7 (range: 2.9-5.7) years and PLE started a median of 3.1 (range: 0.9-4.7) years later. Five patients required a second procedure 2-8 months later. Complications were limited (spillage of glue in portal branch, transient cholangitis, and caustic duodenal bleeding). Six of seven patients reported significant improvement in quality of life and normalization of albumin levels after limited follow-up (p < .01). One patient (Fontan at 2.9 years; age 16.4 years) had PB for 2 years. Selective transthoracic cone-beam-directed puncture of left and right paratracheal lymphatics with n-BCA embolization of distal lymphatic fistulae resulted in lasting absence of tracheal casts (11 months).
    Conclusions: Embolization of periportal/peritracheal lymphatics is a promising technique in Fontan patients with PLE/PB. Larger series are required to determine incidence and reasons of success/failure, with long-term results and effects on liver function.
    MeSH term(s) Adolescent ; Bronchitis/diagnosis ; Bronchitis/etiology ; Bronchitis/therapy ; Child ; Embolization, Therapeutic/adverse effects ; Enbucrilate/administration & dosage ; Enbucrilate/adverse effects ; Feasibility Studies ; Fistula/diagnostic imaging ; Fistula/etiology ; Fistula/therapy ; Fontan Procedure/adverse effects ; Heart Defects, Congenital/surgery ; Humans ; Lymphatic Diseases/diagnostic imaging ; Lymphatic Diseases/etiology ; Lymphatic Diseases/therapy ; Protein-Losing Enteropathies/diagnosis ; Protein-Losing Enteropathies/etiology ; Protein-Losing Enteropathies/therapy ; Retrospective Studies ; Treatment Failure ; Treatment Outcome
    Chemical Substances Enbucrilate (F8CEP82QNP)
    Language English
    Publishing date 2019-10-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.28501
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1226: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Acute Cardiovascular Manifestations in 286 Children with Multisystem Inflammatory Syndrome Associated with COVID-19 Infection in Europe

    Valverde, Israel / Singh, Yogen / Sanchez-de-Toledo, Joan / Theocharis, Paraskevi / Chikermane, Ashish / Di Filippo, Sylvie / Kucinska, Beata / Mannarino, Savina / Tamariz-Martel, Amalia / Gutierrez-Larraya, Federico / Soda, Giridhar / Vandekerckhove, Kristof / Gonzalez Barlatay, Francisco / McMahon, Colin Joseph / Marcora, Simona Anna / Napoleone, Carlo Pace / Duong, Phuoc / Tuo, Giulia / Deri, Antigoni /
    Nepali, Gauri / Ilina, Maria / Ciliberti, Paolo / Iriart, Xavier / Hubrechts, Jelena / Kuipers, Irene Mariette / Sousa, Ana R. / Donti, Andrea / Sharpe, Abigail / Reinhardt, Zdenka / Cairello, Francesca / De Wolf, Daniel / Vieira, Marisa / Lazea, Cecilia / Gran, Ferran / Medrano-Lopez, Constancio / Ortiz-Garrido, Almudena / Vukomanovic, Vladislav / Brent, Bernadette Elisabeth / Milanesi, Ornella / Dewals, Wendy / Manso, Begoña / Valsangiacomo-Buchel, Emanuela / Francisco, Andreia / Seghaye, Marie-Christine / Loeckx, Isabelle / Rodriguez-Gonzalez, Moises / Rey-García, Susana Maria / Ziesenitz, Victoria C. / Bordin, Giulia / Doros, Gabriela / Grangl, Gernot / Fadl, Shalan Uaid / Perminow, Karl Viktor / Centeno, Fernando / Pinto, Fatima / Niemelä, Jussi / Miller, Owen

    SSRN Electronic Journal ; ISSN 1556-5068

    2020  

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.2139/ssrn.3634853
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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