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Article ; Online: Influence of glycan structure on the colonization of

Chun, Ye-Yu / Tan, Kai Sen / Yu, Lisa / Pang, Michelle / Wong, Ming Hui Millie / Nakamoto, Rei / Chua, Wan-Zhen / Huee-Ping Wong, Amanda / Lew, Zhe Zhang Ryan / Ong, Hsiao Hui / Chow, Vincent T / Tran, Thai / Yun Wang, De / Sham, Lok-To

Proceedings of the National Academy of Sciences of the United States of America

2023  Volume 120, Issue 13, Page(s) e2213584120

Abstract: Virtually all living cells are encased in glycans. They perform key cellular functions such as immunomodulation and cell-cell recognition. Yet, how their composition and configuration affect their functions remains enigmatic. Here, we constructed ... ...

Abstract Virtually all living cells are encased in glycans. They perform key cellular functions such as immunomodulation and cell-cell recognition. Yet, how their composition and configuration affect their functions remains enigmatic. Here, we constructed isogenic capsule-switch mutants harboring 84 types of capsular polysaccharides (CPSs) in
MeSH term(s) Humans ; Streptococcus pneumoniae/genetics ; Streptococcus pneumoniae/metabolism ; Epithelial Cells ; Respiratory System ; Polysaccharides/metabolism ; Nose
Chemical Substances Polysaccharides
Language English
Publishing date 2023-03-21
Publishing country United States
Document type Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID 209104-5
ISSN 1091-6490 ; 0027-8424
ISSN (online) 1091-6490
ISSN 0027-8424
DOI 10.1073/pnas.2213584120
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Zs.A 1148: Show issues Location:
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