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  1. Article ; Online: Industry collaboration with dermatology education during medical school.

    Mangion, Sean E / Hughes, Sarah A L

    Journal of cosmetic dermatology

    2023  Volume 22, Issue 5, Page(s) 1706–1707

    MeSH term(s) Humans ; Schools, Medical ; Dermatology/education ; Educational Status
    Language English
    Publishing date 2023-01-16
    Publishing country England
    Document type Letter
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.15627
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  2. Article: Hazard assessment of chemical constituents in biocide formulations used in offshore oil and gas operations

    Bejarano, Adriana C. / Hughes, Sarah A. / Saunders, David

    Marine pollution bulletin. 2022 Aug. 21,

    2022  

    Abstract: Biocides used in offshore oil and gas operations could be present in water discharges, and thus identifying such chemicals and their hazard could help address concerns regarding non-target organisms. Aquatic toxicity data, queried from different sources ... ...

    Abstract Biocides used in offshore oil and gas operations could be present in water discharges, and thus identifying such chemicals and their hazard could help address concerns regarding non-target organisms. Aquatic toxicity data, queried from different sources and augmented with predictive models, were used to develop species sensitivity distributions and their corresponding 5th percentile hazard concentrations (HC5s). Curated data, including over 1000 empirical records for 137 species, indicated no evidence of bias when comparing sensitivity between marine and freshwater species, even when predicted data were used. HC5s facilitated estimation of an acute-to-chronic ratio (ACR = 10), appropriate for most chemicals and useful in filling gaps. Comparison of chronic-HC5s with the default approach for deriving predicted no effect concentrations showed that the latter systematically overstates aquatic hazard. The present approach shows promise of using acute-to-chronic HC5 ratios for defining assessment factors for different chemical classes, instead of the use of generic assessment factors.
    Keywords biocides ; freshwater ; hazard characterization ; marine pollution ; oils ; toxicity
    Language English
    Dates of publication 2022-0821
    Publishing place Elsevier Ltd
    Document type Article
    Note Pre-press version
    ZDB-ID 2001296-2
    ISSN 1879-3363 ; 0025-326X
    ISSN (online) 1879-3363
    ISSN 0025-326X
    DOI 10.1016/j.marpolbul.2022.114076
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  3. Article ; Online: Hazard assessment of chemical constituents in biocide formulations used in offshore oil and gas operations.

    Bejarano, Adriana C / Hughes, Sarah A / Saunders, David

    Marine pollution bulletin

    2022  Volume 183, Page(s) 114076

    Abstract: Biocides used in offshore oil and gas operations could be present in water discharges, and thus identifying such chemicals and their hazard could help address concerns regarding non-target organisms. Aquatic toxicity data, queried from different sources ... ...

    Abstract Biocides used in offshore oil and gas operations could be present in water discharges, and thus identifying such chemicals and their hazard could help address concerns regarding non-target organisms. Aquatic toxicity data, queried from different sources and augmented with predictive models, were used to develop species sensitivity distributions and their corresponding 5th percentile hazard concentrations (HC5s). Curated data, including over 1000 empirical records for 137 species, indicated no evidence of bias when comparing sensitivity between marine and freshwater species, even when predicted data were used. HC5s facilitated estimation of an acute-to-chronic ratio (ACR = 10), appropriate for most chemicals and useful in filling data gaps. Comparison of chronic-HC5s with the default approach for deriving predicted no effect concentrations showed that the latter systematically overstates aquatic hazard. The present approach shows promise of using acute-to-chronic HC5 ratios for defining assessment factors for different chemical classes, instead of the use of generic assessment factors.
    MeSH term(s) Aquatic Organisms ; Disinfectants/toxicity ; Fresh Water ; Risk Assessment ; Species Specificity ; Water ; Water Pollutants, Chemical/toxicity
    Chemical Substances Disinfectants ; Water Pollutants, Chemical ; Water (059QF0KO0R)
    Language English
    Publishing date 2022-08-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2001296-2
    ISSN 1879-3363 ; 0025-326X
    ISSN (online) 1879-3363
    ISSN 0025-326X
    DOI 10.1016/j.marpolbul.2022.114076
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  4. Article ; Online: Are Vertebrates Still Needed in Routine Whole Effluent Toxicity Testing for Oil and Gas Discharges?

    Hughes, Sarah A / Maloney, Erin M / Bejarano, Adriana C

    Environmental toxicology and chemistry

    2021  Volume 40, Issue 5, Page(s) 1255–1265

    Abstract: Routine whole effluent toxicity (WET) testing is commonly used to monitor effluent discharges for regulatory compliance in North America. However, the use of fish in WET testing raises ethical concerns and therefore an important question to be explored ... ...

    Abstract Routine whole effluent toxicity (WET) testing is commonly used to monitor effluent discharges for regulatory compliance in North America. However, the use of fish in WET testing raises ethical concerns and therefore an important question to be explored is whether invertebrates can be used to reduce and/or replace the need for vertebrate testing. The present study evaluated WET data collected for regulatory compliance between 2003 and 2019 (n = 2581 endpoints) from 20 different stationary onshore and offshore oil and gas facilities located across Canada and the United States. Our objective was to assess the relative sensitivity between vertebrates (i.e., fish) and invertebrates in paired samples and to evaluate trends in WET compliance. Despite the variability in testing endpoints, invertebrates displayed equal to or greater sensitivity to tested effluents than fish. For example, based on no-observed-effect concentrations for survival and growth, Americamysis bahia was found to be protective of Menidia beryllina in 90% of endpoint comparisons (n = 336). The results also indicated that regulatory compliance was high (94-100%), with most WET tests passing the established criteria by large margins (79-251%). The results of this comprehensive analysis of historical WET data can be used to improve future permit testing requirements and help answer the question of whether fish tests are needed for routine WET testing. Environ Toxicol Chem 2021;40:1255-1265. © 2020 SETAC.
    MeSH term(s) Animals ; Crustacea ; Fishes ; Invertebrates ; Toxicity Tests ; United States ; Water Pollutants, Chemical/analysis ; Water Pollutants, Chemical/toxicity
    Chemical Substances Water Pollutants, Chemical
    Language English
    Publishing date 2021-04-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 46234-2
    ISSN 1552-8618 ; 0730-7268
    ISSN (online) 1552-8618
    ISSN 0730-7268
    DOI 10.1002/etc.4963
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  5. Article ; Online: Mothers' Experiences During the 2022 Infant Formula Shortage in Washington D.C.

    Sylvetsky, Allison C / Hughes, Sarah A / Kuttamperoor, Janae T / Moore, Hailey R / Murphy, Jeanne / Sacheck, Jennifer / Smith, Emily R

    Maternal and child health journal

    2023  Volume 28, Issue 5, Page(s) 873–886

    Abstract: Introduction: An unprecedented shortage of infant formula occurred in the United States (U.S.) in 2022 and posed widespread challenges to infant feeding nationwide. The purpose of this study is to investigate mothers' experiences during the 2022 infant ... ...

    Abstract Introduction: An unprecedented shortage of infant formula occurred in the United States (U.S.) in 2022 and posed widespread challenges to infant feeding nationwide. The purpose of this study is to investigate mothers' experiences during the 2022 infant formula shortage and its perceived impacts on infants' diet and health.
    Methods: Mothers (n = 45) of infants under 8 months old from Washington D.C. were invited to participate in a virtual study meeting during the summer of 2022. Mothers completed surveys regarding their demographics, infants' anthropometrics, infant feeding practices, information they have received about infant feeding, and knowledge about infant feeding practices. They then participated in a qualitative interview about their experiences during the infant formula shortage.
    Results: Overarching themes were: the shortage (1) had adverse impacts on mothers' mental and emotional health; (2) had significant financial and intangible costs; (3) led to changes in infant feeding practices; (4) social and family networks were helpful in navigating the shortage; and (5) mothers felt fortunate to have resources to breastfeed and/or obtain formula.
    Discussion: The infant formula shortage adversely impacted mothers' mental and emotional health, and was costly, in terms of financial and intangible costs. Findings demonstrate the need to develop clinical and policy approaches to support mothers in feeding their infants and provide education about safe infant feeding practices.
    MeSH term(s) Infant ; Female ; Humans ; Infant Formula ; Washington ; Mothers/psychology ; Breast Feeding/psychology ; Feeding Behavior ; Health Knowledge, Attitudes, Practice
    Language English
    Publishing date 2023-12-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1339905-6
    ISSN 1573-6628 ; 1092-7875
    ISSN (online) 1573-6628
    ISSN 1092-7875
    DOI 10.1007/s10995-023-03860-9
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    Zs.A 6170: Show issues Location:
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  6. Article: Are Vertebrates Still Needed in Routine Whole Effluent Toxicity Testing for Oil and Gas Discharges?

    Hughes, Sarah A / Maloney, Erin M / Bejarano, Adriana C

    Environmental toxicology and chemistry. 2021 May, v. 40, no. 5

    2021  

    Abstract: Routine whole effluent toxicity (WET) testing is commonly used to monitor effluent discharges for regulatory compliance in North America. However, the use of fish in WET testing raises ethical concerns and therefore an important question to be explored ... ...

    Abstract Routine whole effluent toxicity (WET) testing is commonly used to monitor effluent discharges for regulatory compliance in North America. However, the use of fish in WET testing raises ethical concerns and therefore an important question to be explored is whether invertebrates can be used to reduce and/or replace the need for vertebrate testing. The present study evaluated WET data collected for regulatory compliance between 2003 and 2019 (n = 2581 endpoints) from 20 different stationary onshore and offshore oil and gas facilities located across Canada and the United States. Our objective was to assess the relative sensitivity between vertebrates (i.e., fish) and invertebrates in paired samples and to evaluate trends in WET compliance. Despite the variability in testing endpoints, invertebrates displayed equal to or greater sensitivity to tested effluents than fish. For example, based on no‐observed‐effect concentrations for survival and growth, Americamysis bahia was found to be protective of Menidia beryllina in 90% of endpoint comparisons (n = 336). The results also indicated that regulatory compliance was high (94–100%), with most WET tests passing the established criteria by large margins (79–251%). The results of this comprehensive analysis of historical WET data can be used to improve future permit testing requirements and help answer the question of whether fish tests are needed for routine WET testing. Environ Toxicol Chem 2021;40:1255–1265. © 2020 SETAC
    Keywords Menidia beryllina ; chemistry ; compliance ; ecotoxicology ; ethics ; fish ; oils ; toxicity ; Canada
    Language English
    Dates of publication 2021-05
    Size p. 1255-1265.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note NAL-AP-2-clean ; JOURNAL ARTICLE
    ZDB-ID 46234-2
    ISSN 1552-8618 ; 0730-7268
    ISSN (online) 1552-8618
    ISSN 0730-7268
    DOI 10.1002/etc.4963
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  7. Article: Promoting self-management and patient independence.

    Hughes, Sarah A

    Nursing standard (Royal College of Nursing (Great Britain) : 1987)

    2004  Volume 19, Issue 10, Page(s) 47–52; quiz 54, 56

    Abstract: This article explains the importance of patient-centred care, and explores the factors affecting self-management and patient independence. ...

    Abstract This article explains the importance of patient-centred care, and explores the factors affecting self-management and patient independence.
    MeSH term(s) Adaptation, Psychological ; Attitude to Health ; Health Behavior ; Health Promotion/methods ; Humans ; Inservice Training ; Nurse's Role ; Nurse-Patient Relations ; Patient Education as Topic/methods ; Self Care/methods ; United Kingdom
    Language English
    Publishing date 2004-11
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 645016-7
    ISSN 2047-9018 ; 0029-6570
    ISSN (online) 2047-9018
    ISSN 0029-6570
    DOI 10.7748/ns2004.11.19.10.47.c3761
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    Zs.MO 273: Show issues

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  8. Article: The development of an intrauterine device/intrauterine system computer-assisted learning package.

    Hughes, Sarah A

    The journal of family planning and reproductive health care

    2004  Volume 30, Issue 2, Page(s) 116–117

    MeSH term(s) CD-ROM ; Clinical Competence ; Computer-Assisted Instruction/methods ; Family Planning Services/education ; Female ; Humans ; Inservice Training ; Intrauterine Devices/standards ; Program Development ; United Kingdom
    Language English
    Publishing date 2004-04-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2038472-5
    ISSN 1471-1893
    ISSN 1471-1893
    DOI 10.1783/147118904322995528
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    Zs.MO 316: Show issues
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  9. Article ; Online: Terrestrial Toxicity of Synthetic Gas-to-Liquid versus Crude Oil-Derived Drilling Fluids in Soil.

    Arneson Westbrook, Lisa / Chase, Darcy A / Mudge, Joseph / Hughes, Sarah A / Lyon, Delina / Dong, Meijun / Carr, Deborah / Anderson, Todd A

    Environmental toxicology and chemistry

    2020  Volume 39, Issue 3, Page(s) 721–730

    Abstract: Unlike most other conventional petroleum products that are derived from crude oil, gas-to-liquids (GTLs) are petroleum products that are synthesized from natural gas (methane). This process results in GTL products having no sulfur and low aromatic ... ...

    Abstract Unlike most other conventional petroleum products that are derived from crude oil, gas-to-liquids (GTLs) are petroleum products that are synthesized from natural gas (methane). This process results in GTL products having no sulfur and low aromatic content, so they should have less impact on human health and the environment compared with crude oil-derived products. The GTLs have been registered for use as nonaqueous base fluids (NABFs) in drilling muds, which aid in the process of drilling wells for oil and gas extraction; it is through these uses and others that they enter terrestrial environments. The primary objective of the present study was to determine whether GTLs were less toxic to terrestrial soil biota than conventional NABFs used for land-based drilling, such as diesel and low-toxicity mineral oil (LTMO). A second objective was to understand the fate and impact of these fluids under more realistic soil and aging conditions of a common west Texas (USA) oil-producing region (i.e., sandy loam soil with low organic matter and a hot arid climate). Acute terrestrial toxicity studies were conducted on the soft-bodied terrestrial invertebrate earthworm (Eisenia fetida) along with 3 plant species-alfalfa (Medicago stavia), thickspike wheatgrass (Elymus lanceolatus), and fourwing saltbrush (Atriplex canescens). We also assessed changes in microbial community structure of the soils following additions of NABF. Overall, the GTL NABFs had lower toxicity compared with conventional NABFs like diesel and LTMO, as measured by invertebrate toxicity, plant seed germination, and impact on the microbial community. Environ Toxicol Chem 2020;39:721-730. © 2020 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals, Inc. on behalf of SETAC.
    MeSH term(s) Animals ; Atriplex/drug effects ; Elymus/drug effects ; Medicago sativa/drug effects ; Microbiota/drug effects ; Oil and Gas Industry ; Oligochaeta/drug effects ; Petroleum/adverse effects ; Soil Microbiology ; Texas
    Chemical Substances Petroleum
    Language English
    Publishing date 2020-02-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 46234-2
    ISSN 1552-8618 ; 0730-7268
    ISSN (online) 1552-8618
    ISSN 0730-7268
    DOI 10.1002/etc.4658
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  10. Article: Terrestrial Toxicity of Synthetic Gas‐to‐Liquid versus Crude Oil–Derived Drilling Fluids in Soil

    Arneson Westbrook, Lisa / Chase, Darcy A / Mudge, Joseph / Hughes, Sarah A / Lyon, Delina / Dong, Meijun / Carr, Deborah / Anderson, Todd A

    Environmental toxicology and chemistry. 2020 Mar., v. 39, no. 3

    2020  

    Abstract: Unlike most other conventional petroleum products that are derived from crude oil, gas‐to‐liquids (GTLs) are petroleum products that are synthesized from natural gas (methane). This process results in GTL products having no sulfur and low aromatic ... ...

    Abstract Unlike most other conventional petroleum products that are derived from crude oil, gas‐to‐liquids (GTLs) are petroleum products that are synthesized from natural gas (methane). This process results in GTL products having no sulfur and low aromatic content, so they should have less impact on human health and the environment compared with crude oil–derived products. The GTLs have been registered for use as nonaqueous base fluids (NABFs) in drilling muds, which aid in the process of drilling wells for oil and gas extraction; it is through these uses and others that they enter terrestrial environments. The primary objective of the present study was to determine whether GTLs were less toxic to terrestrial soil biota than conventional NABFs used for land‐based drilling, such as diesel and low‐toxicity mineral oil (LTMO). A second objective was to understand the fate and impact of these fluids under more realistic soil and aging conditions of a common west Texas (USA) oil‐producing region (i.e., sandy loam soil with low organic matter and a hot arid climate). Acute terrestrial toxicity studies were conducted on the soft‐bodied terrestrial invertebrate earthworm (Eisenia fetida) along with 3 plant species—alfalfa (Medicago stavia), thickspike wheatgrass (Elymus lanceolatus), and fourwing saltbrush (Atriplex canescens). We also assessed changes in microbial community structure of the soils following additions of NABF. Overall, the GTL NABFs had lower toxicity compared with conventional NABFs like diesel and LTMO, as measured by invertebrate toxicity, plant seed germination, and impact on the microbial community. Environ Toxicol Chem 2020;39:721–730. © 2020 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals, Inc. on behalf of SETAC.
    Keywords Atriplex canescens ; Eisenia fetida ; Elymus lanceolatus ; Medicago ; arid zones ; community structure ; drilling ; earthworms ; human health ; methane ; microbial communities ; mineral oil ; natural gas ; organic matter ; petroleum ; sandy loam soils ; seed germination ; sulfur ; toxicity ; toxicity testing ; wells ; Texas
    Language English
    Dates of publication 2020-03
    Size p. 721-730.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 46234-2
    ISSN 1552-8618 ; 0730-7268
    ISSN (online) 1552-8618
    ISSN 0730-7268
    DOI 10.1002/etc.4658
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