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  1. Article ; Online: Repetitive use of levosimendan in severe functional tricuspid regurgitation.

    Lim, Pascal / Sharifi, Julia / Huguet, Raphaelle / Gallet, Romain / Aouate, David

    European heart journal. Acute cardiovascular care

    2023  Volume 12, Issue 5, Page(s) 336–337

    MeSH term(s) Humans ; Tricuspid Valve Insufficiency/drug therapy ; Tricuspid Valve Insufficiency/surgery ; Simendan/therapeutic use
    Chemical Substances Simendan (349552KRHK)
    Language English
    Publishing date 2023-03-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2663340-1
    ISSN 2048-8734 ; 2048-8726
    ISSN (online) 2048-8734
    ISSN 2048-8726
    DOI 10.1093/ehjacc/zuad013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: PET/CT for osteoarticular septic grafts in endocarditis: A large monocentric cohort.

    Hugues, Benjamin / Emsen, Berivan / Pina Vegas, Laura / Lepeule, Raphaël / Ternacle, Julien / Huguet, Raphaëlle / Decousser, Jean-Winoc / Fiore, Antonio / Lim, Pascal / Itti, Emmanuel / Chevalier, Xavier / Abulizi, Mukedaizi / Eymard, Florent

    Joint bone spine

    2023  Volume 90, Issue 5, Page(s) 105577

    MeSH term(s) Humans ; Positron Emission Tomography Computed Tomography ; Endocarditis ; Fluorodeoxyglucose F18 ; Radiopharmaceuticals ; Prosthesis-Related Infections
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D) ; Radiopharmaceuticals
    Language English
    Publishing date 2023-04-17
    Publishing country France
    Document type Letter
    ZDB-ID 2020487-5
    ISSN 1778-7254 ; 1297-319X
    ISSN (online) 1778-7254
    ISSN 1297-319X
    DOI 10.1016/j.jbspin.2023.105577
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Usefulness of Doppler Transthoracic Echocardiography for the Diagnosis of Wide-QRS Complex Tachycardia.

    Hamon, David / Moulin, Thibaut / Nicolas, Eroan / Labbé, Jean-Philippe / Ternacle, Julien / Huguet, Raphaelle / Lim, Pascal / Derumeaux, Geneviève / Teiger, Emmanuel / Miller, John M / Lellouche, Nicolas

    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

    2023  Volume 36, Issue 8, Page(s) 888–891

    MeSH term(s) Humans ; Tachycardia/diagnosis ; Echocardiography, Doppler ; Arrhythmias, Cardiac/diagnosis ; Electrocardiography ; Diagnosis, Differential
    Language English
    Publishing date 2023-03-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1035622-8
    ISSN 1097-6795 ; 0894-7317
    ISSN (online) 1097-6795
    ISSN 0894-7317
    DOI 10.1016/j.echo.2023.03.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Blood Cultures for the Diagnosis of Infective Endocarditis: What Is the Benefit of Prolonged Incubation?

    Fihman, Vincent / Faury, Hélène / Moussafeur, Amina / Huguet, Raphaelle / Galy, Adrien / Gallien, Sébastien / Lim, Pascal / Lepeule, Raphaël / Woerther, Paul-Louis

    Journal of clinical medicine

    2021  Volume 10, Issue 24

    Abstract: To assess the need for prolonged incubation of blood culture bottles beyond five days for the diagnosis of infectious endocarditis (IE), we conducted a retrospective cohort study of 6109 sets of two blood culture bottles involving 1211 patients admitted ... ...

    Abstract To assess the need for prolonged incubation of blood culture bottles beyond five days for the diagnosis of infectious endocarditis (IE), we conducted a retrospective cohort study of 6109 sets of two blood culture bottles involving 1211 patients admitted to the Henri Mondor University Hospital for suspicion of IE between 1 January 2016 and 31 December 2019. Among the 322 patients with IE, 194 had positive blood cultures in our centre. Only one patient with a time-to-positivity blood culture of more than 120 h (5 days) was found. The main cause for the 22 patients with positive blood cultures after five days was contamination with
    Language English
    Publishing date 2021-12-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10245824
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Severe Heart Failure Associated With Tachycardia-Induced Cardiomyopathy Due to Incessant Atrioventricular Re-Entrant Tachycardia.

    Moulin, Thibaut / Landes, Rosanna / Ouazana, Victoria / Abehsira, Guillaume / Lim, Pascal / Huguet, Raphaelle / Damy, Thibaud / Teiger, Emmanuel / Lellouche, Nicolas / Hamon, David

    JACC. Case reports

    2021  Volume 3, Issue 3, Page(s) 479–483

    Abstract: Short RP interval atrioventricular re-entrant tachycardias do not typically present as an incessant form. We present 2 cases of incessant atrioventricular re-entrant tachycardias leading to tachycardia-induced cardiomyopathy with severe heart failure ... ...

    Abstract Short RP interval atrioventricular re-entrant tachycardias do not typically present as an incessant form. We present 2 cases of incessant atrioventricular re-entrant tachycardias leading to tachycardia-induced cardiomyopathy with severe heart failure presentation in middle-aged adults. Both underwent accessory pathway ablation and recovered normal left ventricle function before hospital discharge. (
    Language English
    Publishing date 2021-02-03
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2020.11.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Characteristics of patients with infective endocarditis and no underlying cardiac conditions.

    Radjabaly Mandjee, Aleyya / Filippetti, Laura / Goehringer, François / Duval, Xavier / Botelho-Nevers, Elisabeth / Tribouilloy, Christophe / Huguet, Raphaëlle / Chirouze, Catherine / Erpelding, Marie-Line / Hoen, Bruno / Selton-Suty, Christine / Agrinier, Nelly / Lefèvre, Benjamin

    Infectious diseases (London, England)

    2022  Volume 54, Issue 9, Page(s) 656–665

    Abstract: Background: Infective endocarditis (IE) typically occurs in patients with underlying cardiac conditions (UCC). Little is known about IE in patients without UCC. We aimed to describe the clinical, microbiological and imaging characteristics, management, ... ...

    Abstract Background: Infective endocarditis (IE) typically occurs in patients with underlying cardiac conditions (UCC). Little is known about IE in patients without UCC. We aimed to describe the clinical, microbiological and imaging characteristics, management, and in-hospital mortality of IE patients without UCC.
    Methods: We analysed the data of patients with definite IE included in an observatory between 1st January 2009 and 31st December 2019. We described patients without UCC compared to those with UCC.
    Results: Of 1502 IE patients, 475 (31.6%) had no UCC. They were younger (median 64.0 [19.0-101.0] vs. 70.0 [18.0-104.0] years,
    Conclusion: Patients with IE and no UCC were younger than those with UCC, had specific comorbidities and portals of entry, and a more severe disease course.
    MeSH term(s) Endocarditis/epidemiology ; Endocarditis/microbiology ; Endocarditis, Bacterial/epidemiology ; Endocarditis, Bacterial/microbiology ; Enterococcus ; Humans ; Retrospective Studies ; Staphylococcus ; Streptococcus
    Language English
    Publishing date 2022-05-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2839775-7
    ISSN 2374-4243 ; 2374-4235
    ISSN (online) 2374-4243
    ISSN 2374-4235
    DOI 10.1080/23744235.2022.2078404
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Levosimendan Plus Dobutamine in Acute Decompensated Heart Failure Refractory to Dobutamine.

    Juguet, William / Fard, Damien / Faivre, Laureline / Koutsoukis, Athanasios / Deguillard, Camille / Mongardon, Nicolas / Mekontso-Dessap, Armand / Huguet, Raphaelle / Lim, Pascal

    Journal of clinical medicine

    2020  Volume 9, Issue 11

    Abstract: Randomized studies showed that Dobutamine and Levosimendan have similar impact on outcome but their combination has never been assessed in acute decompensated heart failure (ADHF) with low cardiac output. This is a retrospective, single-center study that ...

    Abstract Randomized studies showed that Dobutamine and Levosimendan have similar impact on outcome but their combination has never been assessed in acute decompensated heart failure (ADHF) with low cardiac output. This is a retrospective, single-center study that included 89 patients (61 ± 15 years) admitted for ADHF requiring inotropic support. The first group consisted of patients treated with dobutamine alone (
    Language English
    Publishing date 2020-11-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm9113605
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Clinical spectrum of ischaemic arterial diseases associated with COVID-19: a series of four illustrative cases.

    Guillet, Henri / Gallet, Romain / Pham, Vincent / D'Humières, Thomas / Huguet, Raphaelle / Lim, Pascal / Michel, Marc / Khellaf, Mehdi

    European heart journal. Case reports

    2020  Volume 5, Issue 1, Page(s) ytaa488

    Abstract: Background: Severe coronavirus-induced disease 2019 (COVID-19) leads to acute respiratory distress syndrome with an increased risk of venous thrombo-embolic events. To a much lesser extent, arterial thrombo-embolic events have also been reported in this ...

    Abstract Background: Severe coronavirus-induced disease 2019 (COVID-19) leads to acute respiratory distress syndrome with an increased risk of venous thrombo-embolic events. To a much lesser extent, arterial thrombo-embolic events have also been reported in this setting.
    Case summary: Here, we describe four different cases of COVID-19 infection with ischaemic arterial events, such as a myocardial infarction with high thrombus load, ischaemic stroke on spontaneous thrombosis of the aortic valve, floating thrombus with mesenteric, splenic and renal infarction, and acute limb ischaemia.
    Discussion: Cardiovascular risk factors such as hypertension, obesity, and diabetes are comorbidities most frequently found in patients with a severe COVID-19 infection and are associated with a higher death rate. Our goal is to provide an overview of the clinical spectrum of ischaemic arterial events that may either reveal or complicate COVID-19. Several suspected pathophysiological mechanisms could explain the association between cardiovascular events and COVID-19 (role of systemic inflammatory response syndrome, endothelial dysfunction, activation of coagulation cascade leading to a hypercoagulability state, virus-induced secondary antiphospholipid syndrome). We need additional studies of larger size, to estimate the incidence of these arterial events and to assess the efficacy of anticoagulation therapy.
    Language English
    Publishing date 2020-12-25
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytaa488
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: MitraClip Implantation for Functional Mitral Regurgitation With Coaptation Gap Facilitated by Levosimendan Treatment.

    Koutsoukis, Athanasios / Fard, Damien / Gallet, Romain / Boukantar, Madjid / Teiger, Emmanuel / Nguyen, Annabelle / Huguet, Raphaelle / Lim, Pascal

    JACC. Case reports

    2020  Volume 2, Issue 6, Page(s) 862–865

    Abstract: A patient with severe, symptomatic functional mitral regurgitation was initially considered not suitable for MitraClip (Abbott Vascular, Abbott Park, Illinois) implantation because of non-coapting mitral leaflets. Repeated levosimendan infusions in ... ...

    Abstract A patient with severe, symptomatic functional mitral regurgitation was initially considered not suitable for MitraClip (Abbott Vascular, Abbott Park, Illinois) implantation because of non-coapting mitral leaflets. Repeated levosimendan infusions in combination with intensive diuresis induced sufficient valve coaptation, thus allowing MitraClip implantation to be performed. (
    Language English
    Publishing date 2020-06-17
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2020.04.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Should We Quantify Valvular Calcifications on Cardiac CT in Patients with Infective Endocarditis?

    Chevance, Virgile / Valter, Remi / Nouri, Mohamed Refaat / Sifaoui, Islem / Moussafeur, Amina / Lepeule, Raphael / Bergoend, Eric / Mule, Sebastien / Tacher, Vania / Huguet, Raphaelle / Folliguet, Thierry / Canoui-Poitrine, Florence / Lim, Pascal / Deux, Jean-François

    Journal of clinical medicine

    2021  Volume 10, Issue 19

    Abstract: Background: Evaluate the impact of valvular calcifications measured on cardiac computed tomography (CCT) in patients with infective endocarditis (IE).: Methods: Seventy patients with native IE (36 aortic IE, 31 mitral IE, 3 bivalvular IE) were ... ...

    Abstract Background: Evaluate the impact of valvular calcifications measured on cardiac computed tomography (CCT) in patients with infective endocarditis (IE).
    Methods: Seventy patients with native IE (36 aortic IE, 31 mitral IE, 3 bivalvular IE) were included and explored with CCT between January 2016 and April 2018. Mitral and aortic valvular calcium score (VCS) were measured on unenhanced calcium scoring images, and correlated with clinical, surgical data, and 1-year death rate.
    Results: VCS of patients with mitral IE and no peripheral embolism was higher than those with peripheral embolism (868 (25-1725) vs. 6 (0-95),
    Conclusion: The amount of valvular calcifications on CT was associated with embolism risk, rate of surgery and 1-year risk of death in patients with mitral IE, and germ's type in aortic IE raising the question of their systematic quantification in native IE.
    Language English
    Publishing date 2021-09-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10194458
    Database MEDical Literature Analysis and Retrieval System OnLINE

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