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  1. Article ; Online: Molecular Breast Imaging: A Scientific Review.

    Hunt, Katie N

    Journal of breast imaging

    2024  Volume 3, Issue 4, Page(s) 416–426

    Abstract: Molecular breast imaging (MBI) is a nuclear medicine technique that has evolved considerably over the past two decades. Technical advances have allowed reductions in administered doses to the point that they are now acceptable for screening. The most ... ...

    Abstract Molecular breast imaging (MBI) is a nuclear medicine technique that has evolved considerably over the past two decades. Technical advances have allowed reductions in administered doses to the point that they are now acceptable for screening. The most common radiotracer used in MBI, 99mTc-sestamibi, has a long history of safe use. Biopsy capability has become available in recent years, with early clinical experience demonstrating technically successful biopsies of MBI-detected lesions. MBI has been shown to be an effective supplemental screening tool in women with dense breasts and is also utilized for breast cancer staging, assessment of response to neoadjuvant chemotherapy, problem solving, and as an alternative to breast MRI in women who have a contraindication to MRI. The degree of background parenchymal uptake on MBI shows promise as a tool for breast cancer risk stratification. Radiologist interpretation is guided by a validated MBI lexicon that mirrors the BI-RADS lexicon. With short interpretation times, a fast learning curve for radiologists, and a substantially lower cost than breast MRI, MBI provides many benefits in the practices in which it is utilized. This review will discuss the current state of MBI technology, clinical applications of MBI, MBI interpretation, radiation dose associated with MBI, and the future of MBI.
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 2631-6129
    ISSN (online) 2631-6129
    DOI 10.1093/jbi/wbab039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Molecular Breast Imaging in the Screening Setting.

    Smith, Katherine A / Hunt, Katie N / Rauch, Gaiane M / Fowler, Amy M

    Journal of breast imaging

    2024  Volume 5, Issue 3, Page(s) 240–247

    Abstract: Early detection of breast cancer through screening mammography saves lives. However, the sensitivity of mammography for breast cancer detection is reduced in women with dense breast tissue. Imaging modalities for supplemental breast cancer screening ... ...

    Abstract Early detection of breast cancer through screening mammography saves lives. However, the sensitivity of mammography for breast cancer detection is reduced in women with dense breast tissue. Imaging modalities for supplemental breast cancer screening include MRI, whole breast US, contrast-enhanced mammography, and molecular breast imaging (MBI). Molecular breast imaging with 99mTc-sestamibi is a functional imaging test to identify metabolically active areas in the breast with positioning analogous to mammography. Since 2011, there have been six large, published studies of screening MBI as a supplement to mammography involving over 6000 women from four different institutions. A multicenter, prospective clinical trial of 3000 women comparing breast cancer detection using screening digital breast tomosynthesis alone or in combination with MBI recently completed enrollment. This review focuses on the current evidence of MBI use for supplemental breast cancer screening, the strengths and limitations of MBI, and recent technological advances.
    MeSH term(s) Female ; Humans ; Breast Neoplasms/diagnosis ; Mammography/methods ; Breast Density ; Prospective Studies ; Early Detection of Cancer/methods ; Multicenter Studies as Topic
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Review ; Journal Article
    ISSN 2631-6129
    ISSN (online) 2631-6129
    DOI 10.1093/jbi/wbad011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Mastitis and More: A Pictorial Review of the Red, Swollen, and Painful Breast.

    Woodard, Genevieve A / Bhatt, Asha A / Knavel, Erica M / Hunt, Katie N

    Journal of breast imaging

    2024  Volume 3, Issue 1, Page(s) 113–123

    Abstract: Clinically, acute mastitis presents as a red, swollen, and painful breast. Targeted ultrasound can be performed to evaluate the extent of infection and for an underlying abscess. Noncomplicated mastitis or a small fluid collection may respond to oral ... ...

    Abstract Clinically, acute mastitis presents as a red, swollen, and painful breast. Targeted ultrasound can be performed to evaluate the extent of infection and for an underlying abscess. Noncomplicated mastitis or a small fluid collection may respond to oral antibiotics without further intervention, but a larger or more complex abscess may require single or serial percutaneous aspiration. Breast infections, particularly those complicated by an abscess, can have a prolonged clinical course, and close follow-up is required. Since the clinical presentation and imaging features of acute infectious mastitis can overlap with other etiologies, such as inflammatory breast cancer and idiopathic granulomatous mastitis, a percutaneous biopsy may be indicated to accurately diagnose patients.
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 2631-6129
    ISSN (online) 2631-6129
    DOI 10.1093/jbi/wbaa098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Lymph Node Staging in Newly Diagnosed Breast Cancer: Point-Preoperative Staging Axillary Ultrasound Is Valuable in the Contemporary Evaluation of Newly Diagnosed Breast Cancer.

    Viers, Lyndsay D / Hunt, Katie N

    AJR. American journal of roentgenology

    2021  Volume 218, Issue 4, Page(s) 598–599

    MeSH term(s) Axilla/diagnostic imaging ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/surgery ; Female ; Humans ; Lymph Node Excision ; Lymph Nodes/diagnostic imaging ; Lymph Nodes/pathology ; Lymph Nodes/surgery ; Neoplasm Staging ; Sentinel Lymph Node Biopsy ; Ultrasonography
    Language English
    Publishing date 2021-09-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.21.26812
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.57: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Comment on "Radiation Doses and Risks in Breast Screening".

    Conners, Amy Lynn / Ellis, Richard / Fazzio, Robert T / Hruska, Carrie B / Hunt, Katie N / O'Connor, Michael K / Rhodes, Deborah J / Shermis, Robin

    Journal of breast imaging

    2024  Volume 2, Issue 6, Page(s) 519–520

    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 2631-6129
    ISSN (online) 2631-6129
    DOI 10.1093/jbi/wbaa074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Inter-library loan at ZB MED

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  6. Article ; Online: Leveling the Workload for Radiologists in Diagnostic Mammography: Application of Lean Principles and Heijunka.

    Conners, Amy L / Clark, Sean E / Brandt, Kathleen R / Hunt, Katie N / Chida, Linda M / Tibor, Laura C / Ruter, Royce L / Khanani, Sadia A

    Journal of breast imaging

    2024  Volume 4, Issue 1, Page(s) 61–69

    Abstract: To facilitate the delivery of accurate and timely care to patients in complex environments, process improvement methodologies such as Lean can be very effective. Lean is a quality improvement methodology that seeks to add value for patients and employees ...

    Abstract To facilitate the delivery of accurate and timely care to patients in complex environments, process improvement methodologies such as Lean can be very effective. Lean is a quality improvement methodology that seeks to add value for patients and employees by continuously improving processes and eliminating waste. At our institution, Lean principles were applied to improve efficiency and minimize waste in the diagnostic breast imaging reading room. This paper describes how we applied Lean principles, including plan-do-study-act testing, level-loading (heijunka), and visual management, to level the workload of the diagnostic radiologists in our practice. Implementation of these principles to improve the diagnostic workflow in breast imaging is described along with examples from our practice, including challenges and future opportunities.
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 2631-6129
    ISSN (online) 2631-6129
    DOI 10.1093/jbi/wbab090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: PPV of the Molecular Breast Imaging Lexicon.

    Hunt, Katie N / Conners, Amy Lynn / Samreen, Naziya / Rhodes, Deborah / Johnson, Matthew P / Hruska, Carrie B

    AJR. American journal of roentgenology

    2022  

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-07-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.21.27047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.57: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Molecular Breast Imaging in Patients with Suspicious Calcifications.

    Hunt, Katie N / Hruska, Carrie B / Johnson, Matthew P / Conners, Amy Lynn / O'connor, Michael K / Rhodes, Deborah J / Basappa, Susanna / Wahner-Roedler, Dietlind

    Journal of breast imaging

    2024  Volume 1, Issue 4, Page(s) 303–309

    Abstract: Objective: We evaluated the accuracy of molecular breast imaging (MBI)-a nuclear medicine technique that employs dedicated dual-detector, cadmium zinc telluride gamma cameras to image the functional uptake of a radiopharmaceutical (typically Tc-99m ... ...

    Abstract Objective: We evaluated the accuracy of molecular breast imaging (MBI)-a nuclear medicine technique that employs dedicated dual-detector, cadmium zinc telluride gamma cameras to image the functional uptake of a radiopharmaceutical (typically Tc-99m sestamibi) in the breast-in patients with suspicious calcifications on mammography.
    Methods: Women scheduled for stereotactic biopsy of calcifications detected on 2D digital mammography were prospectively enrolled to undergo MBI before biopsy. Molecular breast imaging was performed with injection of Tc-99m sestamibi and a dual-detector, cadmium zinc telluride gamma camera. Positive findings on either modality were biopsied. High-risk and malignant biopsy findings were excised.
    Results: In 71 participants, 76 areas of calcifications were recommended for biopsy after mammography, and 24 (32%) were malignant, including 20 cases of ductal carcinoma in situ (DCIS) and 4 cases of invasive ductal cancer. Prebiopsy MBI was positive in 17 of the 76 (22%) calcifications, including 10 of 20 (50%) DCISs and 2 of 4 (50%) invasive cancers. The median pathologic size for MBI-positive cancers was 1.5 cm (range 0.5-3.2 cm) compared with 0.9 cm (range 0.1-2.0 cm) for MBI-negative cancers (P = 0.09).Non-mass uptake on MBI led to additional biopsies of 6 sites in 6 patients, and 2 of 6 (33%) MBI-detected incidental lesions showed malignancy; both DCIS contralateral to the mammographically detected calcifications. The overall per-lesion positive and negative predictive values of MBI in this prebiopsy setting were 61% (14 of 23) and 80% (47 of 59), respectively.
    Conclusion: Molecular breast imaging has insufficient negative predictive value to identify calcifications in which biopsy could be avoided. However, among women presenting for biopsy of suspicious calcifications, MBI revealed additional sites of mammographically occult breast cancer.To avoid biopsy of suspicious calcifications on mammography, negative findings on MBI should not be used.
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 2631-6129
    ISSN (online) 2631-6129
    DOI 10.1093/jbi/wbz054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Molecular breast imaging detected invasive lobular carcinoma in dense breasts: A case report.

    Samreen, Naziya / Hunt, Katie N / Hruska, Carrie B / Rhodes, Deborah J

    Clinical case reports

    2019  Volume 7, Issue 3, Page(s) 442–444

    Abstract: This case highlights the role of molecular breast imaging (MBI) in evaluating persistent clinical concerns after a negative diagnostic mammogram and ultrasound. MBI is especially useful in the diagnosis of invasive lobular carcinoma due to its occult ... ...

    Abstract This case highlights the role of molecular breast imaging (MBI) in evaluating persistent clinical concerns after a negative diagnostic mammogram and ultrasound. MBI is especially useful in the diagnosis of invasive lobular carcinoma due to its occult nature on conventional imaging modalities.
    Language English
    Publishing date 2019-01-28
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.1945
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Molecular Breast Imaging in Clinical Practice.

    Dibble, Elizabeth H / Hunt, Katie N / Ehman, Eric C / O'Connor, Michael K

    AJR. American journal of roentgenology

    2020  Volume 215, Issue 2, Page(s) 277–284

    Abstract: OBJECTIVE. ...

    Abstract OBJECTIVE.
    MeSH term(s) Breast Density ; Breast Neoplasms/diagnostic imaging ; Female ; Humans ; Molecular Imaging ; Radiation Injuries/epidemiology ; Risk Assessment
    Language English
    Publishing date 2020-06-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.19.22622
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.57: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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