Article: Late-stage modification of bioactive compounds: Improving druggability through efficient molecular editing.
Acta pharmaceutica Sinica. B
2023 Volume 14, Issue 3, Page(s) 1030–1076
Abstract: Synthetic chemistry plays an indispensable role in drug discovery, contributing to hit compounds identification, lead compounds optimization, candidate drugs preparation, and so on. As Nobel Prize laureate James Black emphasized, "the most fruitful basis ...
| Abstract | Synthetic chemistry plays an indispensable role in drug discovery, contributing to hit compounds identification, lead compounds optimization, candidate drugs preparation, and so on. As Nobel Prize laureate James Black emphasized, "the most fruitful basis for the discovery of a new drug is to start with an old drug" |
|---|---|
| Language | English |
| Publishing date | 2023-11-18 |
| Publishing country | Netherlands |
| Document type | Journal Article ; Review |
| ISSN | 2211-3835 |
| ISSN | 2211-3835 |
| DOI | 10.1016/j.apsb.2023.11.021 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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