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  1. Book ; Conference proceedings: Proceedings of the 2016 International Protein Summit

    Hurt, Ryan T.

    (Nutrition in clinical practice ; volume 32, supplement 1 (April 2017))

    2007  

    Event/congress International Protein Summit (2016, CharlestonSC)
    Author's details contributing editor: Ryan T. Hurt, MD, PhD
    Series title Nutrition in clinical practice ; volume 32, supplement 1 (April 2017)
    Collection
    Language English
    Size 151S Seiten, Illustrationen
    Publisher Sage
    Publishing place Thousand Oaks, CA
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT019340733
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Contributing Editor's Note.

    Hurt, Ryan T

    Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition

    2017  Volume 32, Issue 1_suppl, Page(s) 5S

    Language English
    Publishing date 2017-04-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645074-x
    ISSN 1941-2452 ; 0884-5336
    ISSN (online) 1941-2452
    ISSN 0884-5336
    DOI 10.1177/0884533617693825
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Peptide‐based formula: Clinical applications and benefits

    Mohamed Elfadil, Osman / Shah, Raj N. / Hurt, Ryan T. / Mundi, Manpreet S.

    Nutrition in Clinical Practice. 2023 Apr., v. 38, no. 2 p.318-328

    2023  

    Abstract: The use of enteral nutrition (EN) continues to increase given benefits. However, with this increase in use, it is also becoming evident that enteral feeding intolerance (EFI) is also quite prevalent, leading to the inability to meet nutrition needs in ... ...

    Abstract The use of enteral nutrition (EN) continues to increase given benefits. However, with this increase in use, it is also becoming evident that enteral feeding intolerance (EFI) is also quite prevalent, leading to the inability to meet nutrition needs in many patients. Given the wide variability in the EN population as well as the number of formulas available, there is not a clear consensus regarding the best approach to EFI management. One approach that is emerging to improve EN tolerance is the use of peptide‐based formulas (PBFs). PBFs refer to enteral formulas containing proteins that have been enzymatically hydrolyzed to dipeptides and tripeptides. These hydrolyzed proteins are often combined with higher medium‐chain triglyceride content to generate an enteral formula that is essentially easier to absorb and utilize. Emerging data demonstrate that the use of PBF in patients with EFI may improve clinical outcomes along with a corresponding reduction in healthcare utilization and potentially the cost of care. This review aims to navigate through key clinical applications and benefits of PBF and to discuss relevant data shared in the literature.
    Keywords dipeptides ; enteral feeding ; health services ; hydrolysis ; medium chain triacylglycerols ; tripeptides
    Language English
    Dates of publication 2023-04
    Size p. 318-328.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 645074-x
    ISSN 1941-2452 ; 0884-5336
    ISSN (online) 1941-2452
    ISSN 0884-5336
    DOI 10.1002/ncp.10961
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Symptom presentation by phenotype of postural orthostatic tachycardia syndrome.

    Angeli, Allison M / Salonen, Bradley R / Ganesh, Ravindra / Hurt, Ryan T / Abdalrhim, Ahmed / Mueller, Michael / Volcheck, Mary / Aakre, Christopher

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 205

    Abstract: Postural orthostatic tachycardia syndrome (POTS) presents heterogeneously and is diagnosed when appropriate symptoms are present in conjunction with a heart rate increase of at least 30 beats-per-minute upon standing without orthostatic hypotension. Much ...

    Abstract Postural orthostatic tachycardia syndrome (POTS) presents heterogeneously and is diagnosed when appropriate symptoms are present in conjunction with a heart rate increase of at least 30 beats-per-minute upon standing without orthostatic hypotension. Much of the current understanding of POTS is based on clinical expertise, particularly regarding POTS phenotypes and their potential role in targeting pharmacologic treatment. This study describes the symptom presentation of POTS by phenotypes at a subspecialty POTS clinic. Data was collected prospectively during clinical visits between April 17, 2014 and February 8, 2021. This data was abstracted retrospectively by chart review. Most of the 378 study participants were female (89.9%) with a mean age 23.0 ± 4.9 years. Lightheadedness was the most common (97.6%) symptom and the most disruptive of quality of life (29.9%). Patients reported substantial functional impairment across multiple life domains, with 3.0 ± 2.8 days lost and 4.7 ± 2.3 unproductive days per week. There were no differences in symptom presentation among POTS phenotypes. POTS phenotypes are not distinguishable based on symptoms alone; if phenotyping is sought, testing is necessary. Further research is needed in better classifying POTS phenotypes with the potential goal of tailoring treatment.
    MeSH term(s) Humans ; Female ; Adolescent ; Young Adult ; Adult ; Male ; Postural Orthostatic Tachycardia Syndrome/diagnosis ; Quality of Life ; Retrospective Studies ; Heart Rate/physiology ; Hypotension, Orthostatic
    Language English
    Publishing date 2024-01-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-50886-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Post-COVID-19 syndrome: persistent neuroimaging changes and symptoms 9 months after initial infection.

    Grach, Stephanie L / Ganesh, Ravindra / Messina, Steven A / Hurt, Ryan T

    BMJ case reports

    2022  Volume 15, Issue 4

    Abstract: A previously healthy and active middle-aged woman acquired COVID-19 as an occupational exposure with subsequent persistent post-COVID-19 symptoms including headache, dyspnoea on exertion, chest pressure, tachycardia, anosmia, parosmia, persistent myalgia, ...

    Abstract A previously healthy and active middle-aged woman acquired COVID-19 as an occupational exposure with subsequent persistent post-COVID-19 symptoms including headache, dyspnoea on exertion, chest pressure, tachycardia, anosmia, parosmia, persistent myalgia, vertigo, cognitive decline and fatigue. She presented to a tertiary medical centre for further evaluation after 9 months of persistent symptoms and had a largely unremarkable workup with the exception of a persistently elevated monocyte chemoattractant protein 1, blunted cardiovagal response and non-specific scattered areas of low-level hypometabolism at the bilateral frontal, left precuneus, occipital and parietal regions on PET scan.
    MeSH term(s) COVID-19/complications ; Female ; Headache/etiology ; Humans ; Middle Aged ; Neuroimaging ; SARS-CoV-2 ; Syndrome
    Language English
    Publishing date 2022-04-08
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2021-248448
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Post-COVID Conditions.

    Mueller, Michael R / Ganesh, Ravindra / Hurt, Ryan T / Beckman, Thomas J

    Mayo Clinic proceedings

    2022  Volume 98, Issue 7, Page(s) 1071–1078

    Abstract: Postinfectious syndromes have been described since the Spanish influenza pandemic of 1918. A similar syndrome-post-COVID condition (PCC)-is common; it occurs months after COVID-19 infection and involves fatigue, postexertional malaise, dyspnea, memory ... ...

    Abstract Postinfectious syndromes have been described since the Spanish influenza pandemic of 1918. A similar syndrome-post-COVID condition (PCC)-is common; it occurs months after COVID-19 infection and involves fatigue, postexertional malaise, dyspnea, memory loss, diffuse pain, and orthostasis. The medical, psychosocial, and economic impact of PCC is immense. In the United States, PCC has caused widespread unemployment and billions in lost wages. Risk factors for development of PCC are female sex and severity of acute COVID-19 infection. Proposed pathophysiologic mechanisms include central nervous system inflammation, viral reservoirs, persistent spike protein, cell receptor dysregulation, and autoimmunity. Because presenting symptoms are often vague, the approach to evaluation should be comprehensive with consideration of other diseases that could masquerade as PCC. Treatments of PCC are little researched, are largely expert based, and are likely to evolve as more evidence emerges. Current therapies, which are symptom targeted, include medications and nonpharmacologic therapies such as optimizing fluid intake, compression garments, progressive activity, meditation, biofeedback, cognitive rehabilitation, and addressing concomitant mood disorders. Many patients will enjoy significant improvements in their quality of life with multimodal treatments and longitudinal care.
    MeSH term(s) Humans ; Female ; Male ; Post-Acute COVID-19 Syndrome ; COVID-19/therapy ; Influenza, Human ; Quality of Life ; Autoimmunity ; Fatigue
    Language English
    Publishing date 2022-02-15
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2023.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Peptide-based formula: Clinical applications and benefits.

    Mohamed Elfadil, Osman / Shah, Raj N / Hurt, Ryan T / Mundi, Manpreet S

    Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition

    2023  Volume 38, Issue 2, Page(s) 318–328

    Abstract: The use of enteral nutrition (EN) continues to increase given benefits. However, with this increase in use, it is also becoming evident that enteral feeding intolerance (EFI) is also quite prevalent, leading to the inability to meet nutrition needs in ... ...

    Abstract The use of enteral nutrition (EN) continues to increase given benefits. However, with this increase in use, it is also becoming evident that enteral feeding intolerance (EFI) is also quite prevalent, leading to the inability to meet nutrition needs in many patients. Given the wide variability in the EN population as well as the number of formulas available, there is not a clear consensus regarding the best approach to EFI management. One approach that is emerging to improve EN tolerance is the use of peptide-based formulas (PBFs). PBFs refer to enteral formulas containing proteins that have been enzymatically hydrolyzed to dipeptides and tripeptides. These hydrolyzed proteins are often combined with higher medium-chain triglyceride content to generate an enteral formula that is essentially easier to absorb and utilize. Emerging data demonstrate that the use of PBF in patients with EFI may improve clinical outcomes along with a corresponding reduction in healthcare utilization and potentially the cost of care. This review aims to navigate through key clinical applications and benefits of PBF and to discuss relevant data shared in the literature.
    MeSH term(s) Humans ; Infant, Newborn ; Food, Formulated ; Enteral Nutrition ; Triglycerides ; Nutritional Status ; Peptides/therapeutic use
    Chemical Substances Triglycerides ; Peptides
    Language English
    Publishing date 2023-02-21
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 645074-x
    ISSN 1941-2452 ; 0884-5336
    ISSN (online) 1941-2452
    ISSN 0884-5336
    DOI 10.1002/ncp.10961
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Early History of Home Parenteral Nutrition: From Hospital to Home.

    Hurt, Ryan T / Steiger, Ezra

    Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition

    2018  Volume 33, Issue 5, Page(s) 598–613

    Abstract: Technologic advances in the past century have led to the ability to safely deliver parenteral nutrition (PN) to hospitalized patients. Key breakthroughs included the development of saline and glucose infusions, infusion pumps, macronutrients (lipids, ... ...

    Abstract Technologic advances in the past century have led to the ability to safely deliver parenteral nutrition (PN) to hospitalized patients. Key breakthroughs included the development of saline and glucose infusions, infusion pumps, macronutrients (lipids, dextrose, and amino acids), and central venous catheters. In the 1960s, centrally delivered PN was performed in short-term hospitalized patients by Lincoln James Lawson (North Staffordshire Royal Infirmatory, United Kingdom) and long-term patients by Stanley Dudrick (University of Pennsylvania, United States). These early studies showed that a system was needed that would allow patients with intestinal failure to be discharged from the hospital and receive home PN (HPN). In the late 1960s and early 1970s, Belding Scribner, Maurice Shils, Khursheed Jeejeebhoy, Marvin Ament, Dudrick, and their teams discharged patients from the hospital who then self-administered HPN. Shortly after these early cases of HPN, multidisciplinary centers were established first in North America, and later in Europe, to manage these complex cases. The current article describes the patients treated by these early HPN pioneers, in addition to subsequent case series reported by them and others.
    MeSH term(s) Animals ; Central Venous Catheters/history ; Europe ; History, 20th Century ; Hospitals/history ; Humans ; Infusion Pumps/history ; Intestinal Diseases/history ; Intestinal Diseases/therapy ; Intestines ; North America ; Parenteral Nutrition, Home/history ; Parenteral Nutrition, Total/history ; Patient Discharge
    Language English
    Publishing date 2018-08-23
    Publishing country United States
    Document type Historical Article ; Journal Article ; Review
    ZDB-ID 645074-x
    ISSN 1941-2452 ; 0884-5336
    ISSN (online) 1941-2452
    ISSN 0884-5336
    DOI 10.1002/ncp.10180
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Over-the-Counter Adrenal Supplements: More Than Meets the Eye.

    Hurt, Ryan T / Mundi, Manpreet S

    Mayo Clinic proceedings

    2018  Volume 93, Issue 3, Page(s) 276–277

    MeSH term(s) Dietary Supplements ; Nonprescription Drugs ; Steroids ; Thyroid Gland
    Chemical Substances Nonprescription Drugs ; Steroids
    Language English
    Publishing date 2018-03-03
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2018.01.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The Role of Parenteral Nutrition for Incurable Cancer: Bridging Expectations and Reality.

    Salonen, Bradley R / Mundi, Manpreet S / Hurt, Ryan T / Bonnes, Sara L

    Current nutrition reports

    2021  Volume 10, Issue 3, Page(s) 226–231

    Abstract: Purpose of review: In this review, we examine the role for parenteral nutrition (PN) for nutritional support of patients with advanced, incurable cancer with an emphasis on bridging the divide between expectations and reality.: Recent findings: As ... ...

    Abstract Purpose of review: In this review, we examine the role for parenteral nutrition (PN) for nutritional support of patients with advanced, incurable cancer with an emphasis on bridging the divide between expectations and reality.
    Recent findings: As the rates of cancer have continued to rise worldwide, the utility of PN has continued to be studied. Due to multiple reasons, high-quality research studies have been scarce, and much of the data is based on observational studies. The recent trend appears to support the use of PN in carefully selected patients. Importantly, the effect on quality of life also should be considered when deciding to initiate PN. PN can be a supportive lifeline for patients with advanced, incurable cancer. The medical team should consider each patient individually to decide if PN should be offered. It is of paramount important for the medical team to engage in shared decision-making with the patient and caregiver(s) to ensure that PN is aligned with their goals and wishes.
    MeSH term(s) Humans ; Motivation ; Neoplasms/therapy ; Parenteral Nutrition ; Parenteral Nutrition, Total ; Quality of Life
    Language English
    Publishing date 2021-05-28
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2161-3311
    ISSN (online) 2161-3311
    DOI 10.1007/s13668-021-00361-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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