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  1. Article ; Online: Recent Trends on Production Sources, Biosynthesis Pathways and Antiviral Efficacies of Artemisinin: A Candidate Phytomedicine against SARS-CoV-2.

    Hussain, Adil

    Current pharmaceutical biotechnology

    2023  Volume 24, Issue 15, Page(s) 1859–1880

    Abstract: Background: Artemisinin is a lactone sesquiterpenoid with an endo-peroxide bridge in the 1, 2, 3-trioxane structure employed for the treatment and management of lethal viral diseases. In the current review, emphasis has been given on the production of ... ...

    Abstract Background: Artemisinin is a lactone sesquiterpenoid with an endo-peroxide bridge in the 1, 2, 3-trioxane structure employed for the treatment and management of lethal viral diseases. In the current review, emphasis has been given on the production of artemisinin from natural sources with biosynthesis pathways and potential antiviral activity.
    Methods: A wide-ranging inquiry on artemisinin was made electronically on the basis of articles published in peer-reviewed journals, abstracts, published in conference proceedings, government reports, preprints, books, Master's and Ph.D. theses,
    Results: The evidence reviewed here indicates that out of the hundreds of species of the genus
    Conclusion: On the whole, it is concluded that the primary natural sources of artemisinin and its derivatives are the
    MeSH term(s) Antimalarials/metabolism ; SARS-CoV-2 ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; COVID-19 ; Artemisinins/pharmacology ; Artemisinins/therapeutic use ; Artemisia/chemistry ; Artemisia/metabolism
    Chemical Substances Antimalarials ; Antiviral Agents ; artemisinin (9RMU91N5K2) ; Artemisinins
    Language English
    Publishing date 2023-03-28
    Publishing country Netherlands
    Document type Review ; Journal Article
    ZDB-ID 2132197-8
    ISSN 1873-4316 ; 1389-2010
    ISSN (online) 1873-4316
    ISSN 1389-2010
    DOI 10.2174/1389201024666230327082051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A phylogenetic perspective of antiviral species of the genus

    Hussain, Adil

    Journal of herbal medicine

    2022  Volume 36, Page(s) 100601

    Abstract: Introduction: Different classes of disease-causing viruses are widely distributed universally. Plant-based medicines are anticipated to be effective cures for viral diseases including the COVID-19, instigated by severe acute respiratory syndrome ... ...

    Abstract Introduction: Different classes of disease-causing viruses are widely distributed universally. Plant-based medicines are anticipated to be effective cures for viral diseases including the COVID-19, instigated by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). This study displays the phylogenetic perspective of
    Methods: Data of
    Results: In total, 23
    Discussion: Artemisia
    Language English
    Publishing date 2022-09-28
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2210-8033
    ISSN 2210-8033
    DOI 10.1016/j.hermed.2022.100601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Hazardous or Advantageous: Uncovering the Roles of Heavy Metals and Humic Substances in Shilajit (Phyto-mineral) with Emphasis on Heavy Metals Toxicity and Their Detoxification Mechanisms.

    Hussain, Adil / Saeed, Asma

    Biological trace element research

    2024  

    Abstract: Shilajit is a phyto-mineral diffusion and semi-solid matter used as traditional medicine with extraordinary health benefits. This study provides a comprehensive data on Shilajit with emphasis on heavy metal profile, associated toxicities, and metal ... ...

    Abstract Shilajit is a phyto-mineral diffusion and semi-solid matter used as traditional medicine with extraordinary health benefits. This study provides a comprehensive data on Shilajit with emphasis on heavy metal profile, associated toxicities, and metal detoxification mechanisms by humic substances present in Shilajit. Data was searched across papers and traditional books using Google Scholar, PubMed, Science Direct, Medline, SciELO, Web of Science, and Scopus as key scientific databases. Findings showed that Shilajit is distributed in almost 20 regions of the world with uses against 20 health problems as traditional medicine. With various humic substances, almost 11 biological activities were reported in Shilajit. This phyto-mineral diffusion possesses around 65 heavy metals including the toxic heavy metals like Cu, Al, Pb, As, Cd, and Hg. However, humic substances in Shilajit actively detoxify around 12 heavy metals. The recommended levels of heavy metals by WHO and FDA in herbal drugs is 0.20 and 0.30 ppm for Cd, 1 ppm for Hg, 10.00 ppm for As and Pb, 20 ppm for Cu, and 50 ppm for Zn. The levels of reported metals in Shilajit were found to be lower than the permissible limits set by WHO and FDA, except in few studies where exceeded levels were reported. Shilajit consumption without knowing permissible levels of metals is not safe and could pose serious health problems. Although the humic substances and few metals in Shilajit are beneficial in terms of chelating toxic heavy metals, the data on metal detoxification still needs to be clarified.
    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 445336-0
    ISSN 1559-0720 ; 0163-4984
    ISSN (online) 1559-0720
    ISSN 0163-4984
    DOI 10.1007/s12011-024-04109-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Challenges in Implementing Universal Design of ICT Among Teachers in Higher Education in Norway.

    Hussain, Adil / Sanderson, Norun Christine

    Studies in health technology and informatics

    2022  Volume 297, Page(s) 557–564

    Abstract: Equal access to education for all is a prioritized goal in many parts of the world and included in several national and international regulations. Universal Design (UD) of information and communication technology (ICT) can ensure accessibility of digital ...

    Abstract Equal access to education for all is a prioritized goal in many parts of the world and included in several national and international regulations. Universal Design (UD) of information and communication technology (ICT) can ensure accessibility of digital learning materials (DLMs). However, until recently the implementation of UD of ICT in higher education institutions (HEIs) has been lacking. This study investigates the practical implementation of UD of ICT of DLMs among teachers in HEIs, challenges experienced by them, and what support is offered by their HEI or what support they believe would be helpful when implementing UD in DLMs. Data was collected through interviews and an online survey from a total of twelve faculty members recruited from eight universities in Norway and analyzed using thematic analysis. Findings indicate that teachers in HEIs do not practice UD of ICT on their DLMs, and that they lack training, sufficient time, and practical support from their HEIs to make their DLMs universally designed. The paper concludes that although HEIs appear willing to provide the necessary support and actions to implement UD of ICT, there seems to be a lack of internal policy on UD.
    MeSH term(s) Communication ; Faculty ; Humans ; Information Technology ; Norway ; Universal Design
    Language English
    Publishing date 2022-08-29
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1879-8365
    ISSN (online) 1879-8365
    DOI 10.3233/SHTI220887
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A Preliminary Up-To-Date Review on Pakistani Medicinal Plants with Potential Antioxidant Activity

    Hussain, Adil

    RADS journal of biological research & applied science. 2020, v. 11, no. 1

    2020  

    Abstract: Background: There exist natural antioxidants in plants that scavenge harmful free radicals from the body. Free radicals are species of chemical origin with an unpaired electron and play a pivotal role in combating against health-related problems like ... ...

    Abstract Background: There exist natural antioxidants in plants that scavenge harmful free radicals from the body. Free radicals are species of chemical origin with an unpaired electron and play a pivotal role in combating against health-related problems like lung damage, inflammation, and cardiovascular ailments etc. Antioxidants halt the development of these free radicals called the reactive oxygen species either by chelating the trace elements or by enzymes inhibition. Objectives: The aim of present review was to collect information about Pakistani medicinally important plants with the exploration of their antioxidant potential. Methodology: Total 206 papers were looked over, which were obtained from numerous sources like; Google Scholar, Medline, PubMed, Research Gate, Science Direct, Scopus and Web of Science. Results: Overall, 93 plants representing 44 families with potential antioxidant activity reported from Pakistan have been presented in this review. Maximum number of species from Asteracea, Poaceae and Rutaceae familes were scrutinized for their potential antioxidant activity from Pakistan. Conclusion: The present review clearly designates that the presence of phytochemicals and antioxidant activity of medicinal plants from Pakistan vary with the species of the plants and material/extracts used. From this review, it is recommended to perform comprehensive experimental investigations based on toxicology and ethnopharmacology on these precious plants from Pakistan. It will be advantageous in the provision of trustworthy information to patients and determine further innovative compounds for safer and new drugs development with fewer side effects.
    Keywords Poaceae ; Rutaceae ; antioxidant activity ; inflammation ; lungs ; phytochemicals ; reactive oxygen species ; research ; toxicology ; traditional medicine ; Pakistan
    Language English
    Publishing place Jinnah University for Women
    Document type Article
    ISSN 2521-8573
    DOI 10.37962/jbas.v11i1.275
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Valuing the Recreational Uses of Pakistan’s Wetlands

    Iftikhar Hussain Adil / Ali Dehlavi

    NUST Journal of Social Sciences and Humanities, Vol 3, Iss

    An Application of the Travel Cost Method

    2021  Volume 2

    Abstract: The Keenjhar Lake, Pakistan’s largest freshwater lake and a Ramsar site, is located in the Lower Indus Basin of the Indus Ecoregion. Global 200, which scientifically ranks outstanding terrestrial and aquatic ecosystems in 238 ecoregions worldwide, the ... ...

    Abstract The Keenjhar Lake, Pakistan’s largest freshwater lake and a Ramsar site, is located in the Lower Indus Basin of the Indus Ecoregion. Global 200, which scientifically ranks outstanding terrestrial and aquatic ecosystems in 238 ecoregions worldwide, the Indus Ecoregion is one of the 40 priority Ecoregions. This study uses a single-site truncated count data travel cost method to estimate the access values of visitors to Keenjhar Lake. Policy makers may use these estimates on the recreational value of the lake to assess the returns on conservation investments. A basic version of the model applied to a subset of visitors using charter transportation allows analysis of impacts on welfare measurement from altering assumptions about embarkation points. This study finds the assumption that this category of visitor does not incur travel and time costs before boarding charter transport to be both unrealistic and simplifying, leading in turn to an underestimate of consumer surplus values. The strongest argument in favour of revising data collection and processing strategies in this regard is perhaps the finding that shared and rented transportation is common in developing countries, while cost coefficients tend to figure prominently in welfare measurement irrespective of the functional form.
    Keywords Travel Cost Method ; Truncated Count Data Model ; Ecotourism ; Keenjhar Lake ; Social Sciences ; H
    Subject code 380
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher National University of Sciences and Technology
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Valuing the Recreational Uses of Pakistan’s Wetlands

    Iftikhar Hussain Adil / Ali Dehlavi

    NUST Journal of Social Sciences and Humanities, Vol 3, Iss

    An Application of the Travel Cost Method

    2021  Volume 2

    Abstract: The Keenjhar Lake, Pakistan’s largest freshwater lake and a Ramsar site, is located in the Lower Indus Basin of the Indus Ecoregion. Global 200, which scientifically ranks outstanding terrestrial and aquatic ecosystems in 238 ecoregions worldwide, the ... ...

    Abstract The Keenjhar Lake, Pakistan’s largest freshwater lake and a Ramsar site, is located in the Lower Indus Basin of the Indus Ecoregion. Global 200, which scientifically ranks outstanding terrestrial and aquatic ecosystems in 238 ecoregions worldwide, the Indus Ecoregion is one of the 40 priority Ecoregions. This study uses a single-site truncated count data travel cost method to estimate the access values of visitors to Keenjhar Lake. Policy makers may use these estimates on the recreational value of the lake to assess the returns on conservation investments. A basic version of the model applied to a subset of visitors using charter transportation allows analysis of impacts on welfare measurement from altering assumptions about embarkation points. This study finds the assumption that this category of visitor does not incur travel and time costs before boarding charter transport to be both unrealistic and simplifying, leading in turn to an underestimate of consumer surplus values. The strongest argument in favour of revising data collection and processing strategies in this regard is perhaps the finding that shared and rented transportation is common in developing countries, while cost coefficients tend to figure prominently in welfare measurement irrespective of the functional form.
    Keywords Travel Cost Method ; Truncated Count Data Model ; Ecotourism ; Keenjhar Lake ; Social Sciences ; H
    Subject code 380
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher National University of Sciences and Technology
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: In Search of Exchange Rate Undershooting in Pakistan

    Wajiha Haq Haq / Iftikhar Hussain Adil

    NUST Journal of Social Sciences and Humanities, Vol 2, Iss

    2021  Volume 2

    Abstract: Exchange rate behaviour does not follow very obvious and predicted pattern. Many attempts have been made to predict its behaviour as much as possible. This research re-examines the Dornbusch’s model of exchange rate overshooting caused by price ... ...

    Abstract Exchange rate behaviour does not follow very obvious and predicted pattern. Many attempts have been made to predict its behaviour as much as possible. This research re-examines the Dornbusch’s model of exchange rate overshooting caused by price rigidities. Dornbusch’s assumption of full employment in economy has been violated in this research which creates the possibility of exchange rate undershooting. In response to positive monetary shock, interest rate decreases and exchange rate undershoots its long run equilibrium. This research explains the dynamics of anti-intuitive exchange rate undershooting. Apart from theoretical formations of exchange rate undershooting, this research also analyses Pakistani data for exchange rate undershooting or overshooting in response to increase in money supply. Quarterly data of twenty three years for exchange rate, nominal interest rate, price, real output and money have been taken and vector autoregressive technique has been used. Evidence of exchange rate undershooting in response to positive money supply shock was found. It also gives an important insight into policy making by identifying some probable behaviour of exchange rate.
    Keywords Undershooting ; Saddle Path ; Price Rigidities ; Monetary Shock ; Social Sciences ; H
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher National University of Sciences and Technology
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Perceptions of Glacier Grafting

    Ramsha Munir / Umer Khayyam / Iftikhar Hussain Adil

    Sustainability, Vol 13, Iss 5208, p

    An Indigenous Technique of Water Conservation for Food Security in Gilgit-Baltistan, Pakistan

    2021  Volume 5208

    Abstract: Climate change and disruption in the water cycle patterns are leading to water scarcity. This unsustained water provision is drastically affecting the areas of limited water resources. This research has studied the impacts of climate change on water ... ...

    Abstract Climate change and disruption in the water cycle patterns are leading to water scarcity. This unsustained water provision is drastically affecting the areas of limited water resources. This research has studied the impacts of climate change on water availability and the localized indigenous technique of glacier grafting for sustained water provision. This adaptation strategy helps the water-stressed locality to conserve water for food security. For this reason, 160 self-administered questionnaires were deployed at the household level, and the primary data were analyzed through STATA Software for ordinal logit regression to estimate the results for both restricted and unrestricted models, against the three dependent variables of glacier grafting, glacier melt water and food security. It is found that glacier grafting ensures sustained water provision for irrigation. It increases fertile land and agricultural production to achieve food security. The income of the households from non-/agricultural products leads to afford a better standard of living. The extension of the glacier grafting strategy to curb climatic effects can help global societies to address the food insecurity issue for sustained living.
    Keywords climate change ; glacier melt water ; glacier grafting ; agriculture ; Gilgit-Baltistan ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 333
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Correction

    Ramsha Munir / Tehzeeb Bano / Iftikhar Hussain Adil / Umer Khayyam

    Sustainability, Vol 14, Iss 16, p

    Munir et al. Perceptions of Glacier Grafting: An Indigenous Technique of Water Conservation for Food Security in Gilgit-Baltistan, Pakistan. Sustainability 2021, 13 , 5208

    2022  Volume 10408

    Abstract: The authors would like to make the following corrections about in published paper [.] ...

    Abstract The authors would like to make the following corrections about in published paper [.]
    Keywords n/a ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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