Article ; Online: In Silico Investigation of the Human GTP Cyclohydrolase 1 Enzyme Reveals the Potential of Drug Repurposing Approaches towards the Discovery of Effective BH
International journal of molecular sciences
2023 Volume 24, Issue 2
Abstract: The GTP cyclohydrolase 1 enzyme (GTPCH1) is the rate-limiting enzyme of the tetrahydrobiopterin ( ... ...
Abstract | The GTP cyclohydrolase 1 enzyme (GTPCH1) is the rate-limiting enzyme of the tetrahydrobiopterin (BH |
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MeSH term(s) | Humans ; GTP Cyclohydrolase/genetics ; GTP Cyclohydrolase/chemistry ; Biopterins/pharmacology ; Drug Repositioning ; Molecular Docking Simulation ; Neuralgia/metabolism ; Nitric Oxide/metabolism |
Chemical Substances | GTP Cyclohydrolase (EC 3.5.4.16) ; Biopterins ; Nitric Oxide (31C4KY9ESH) |
Language | English |
Publishing date | 2023-01-07 |
Publishing country | Switzerland |
Document type | Journal Article |
ZDB-ID | 2019364-6 |
ISSN | 1422-0067 ; 1422-0067 ; 1661-6596 |
ISSN (online) | 1422-0067 |
ISSN | 1422-0067 ; 1661-6596 |
DOI | 10.3390/ijms24021210 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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