Article ; Online: GBT1118, a potent allosteric modifier of hemoglobin O
American journal of physiology. Heart and circulatory physiology
2017 Volume 313, Issue 2, Page(s) H381–H391
Abstract: Adaptation to hypoxia requires compensatory mechanisms that affect ... ...
| Abstract | Adaptation to hypoxia requires compensatory mechanisms that affect O |
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| MeSH term(s) | Adaptation, Physiological ; Administration, Oral ; Animals ; Benzaldehydes/administration & dosage ; Benzaldehydes/pharmacokinetics ; Benzaldehydes/pharmacology ; Biomarkers/blood ; Blood Flow Velocity ; Blood Pressure ; Disease Models, Animal ; Heart Rate ; Hypoxia/blood ; Hypoxia/drug therapy ; Hypoxia/physiopathology ; Male ; Mice, Inbred C57BL ; Microcirculation/drug effects ; Niacinamide/administration & dosage ; Niacinamide/analogs & derivatives ; Niacinamide/pharmacokinetics ; Niacinamide/pharmacology ; Oxygen/blood ; Oxyhemoglobins/metabolism ; Regional Blood Flow ; Severity of Illness Index ; Skin/blood supply | |||||
| Chemical Substances | Benzaldehydes ; Biomarkers ; GBT1118 ; Oxyhemoglobins ; Niacinamide (25X51I8RD4) ; Oxygen (S88TT14065) | |||||
| Language | English | |||||
| Publishing date | 2017-05-19 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 603838-4 | |||||
| ISSN | 1522-1539 ; 0363-6135 | |||||
| ISSN (online) | 1522-1539 | |||||
| ISSN | 0363-6135 | |||||
| DOI | 10.1152/ajpheart.00772.2016 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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