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  1. Article: High-precision neural stimulation by a highly efficient candle soot fiber optoacoustic emitter.

    Chen, Guo / Shi, Linli / Lan, Lu / Wang, Runyu / Li, Yueming / Du, Zhiyi / Hyman, Mackenzie / Cheng, Ji-Xin / Yang, Chen

    Frontiers in neuroscience

    2022  Volume 16, Page(s) 1005810

    Abstract: Highly precise neuromodulation with a high efficacy poses great importance in neuroscience. Here we developed a candle soot fiber optoacoustic emitter (CSFOE), capable of generating a high pressure of over 10 MPa with a central frequency of 12.8 MHz, ... ...

    Abstract Highly precise neuromodulation with a high efficacy poses great importance in neuroscience. Here we developed a candle soot fiber optoacoustic emitter (CSFOE), capable of generating a high pressure of over 10 MPa with a central frequency of 12.8 MHz, enabling highly efficient neuromodulation
    Language English
    Publishing date 2022-11-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2022.1005810
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Multi-Scale Label-Free Human Brain Imaging with Integrated Serial Sectioning Polarization Sensitive Optical Coherence Tomography and Two-Photon Microscopy.

    Chang, Shuaibin / Yang, Jiarui / Novoseltseva, Anna / Abdelhakeem, Ayman / Hyman, Mackenzie / Fu, Xinlei / Li, Chenglin / Chen, Shih-Chi / Augustinack, Jean C / Magnain, Caroline / Fischl, Bruce / Mckee, Ann C / Boas, David A / Chen, Ichun Anderson / Wang, Hui

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2023  Volume 10, Issue 35, Page(s) e2303381

    Abstract: The study of aging and neurodegenerative processes in the human brain requires a comprehensive understanding of cytoarchitectonic, myeloarchitectonic, and vascular structures. Recent computational advances have enabled volumetric reconstruction of the ... ...

    Abstract The study of aging and neurodegenerative processes in the human brain requires a comprehensive understanding of cytoarchitectonic, myeloarchitectonic, and vascular structures. Recent computational advances have enabled volumetric reconstruction of the human brain using thousands of stained slices, however, tissue distortions and loss resulting from standard histological processing have hindered deformation-free reconstruction. Here, the authors describe an integrated serial sectioning polarization-sensitive optical coherence tomography (PSOCT) and two photon microscopy (2PM) system to provide label-free multi-contrast imaging of intact brain structures, including scattering, birefringence, and autofluorescence of human brain tissue. The authors demonstrate high-throughput reconstruction of 4 × 4 × 2cm
    MeSH term(s) Humans ; Tomography, Optical Coherence/methods ; Microscopy/methods ; Lipofuscin ; Brain/diagnostic imaging ; Neuroimaging
    Chemical Substances Lipofuscin
    Language English
    Publishing date 2023-10-26
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202303381
    Database MEDical Literature Analysis and Retrieval System OnLINE

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