Article ; Online: Estudio transversal de comorbilidades y medicaciones concomitantes en una cohorte de pacientes infectados por el virus de la inmunodeficiencia humana.
2016 Volume 49, Issue 5, Page(s) 286–293
Abstract: Aim: To assess the prevalence of comorbidities, concomitant therapies and adverse effects associated with the medication in a cohort of patients with HIV infection.: Design: Multicentre cross-sectional study.: Settings: Infectious Diseases or ... ...
Title translation | Cross sectional study of comorbidities and concomitant medications in a cohort of human immunodeficiency virus-infected patients. |
---|---|
Abstract | Aim: To assess the prevalence of comorbidities, concomitant therapies and adverse effects associated with the medication in a cohort of patients with HIV infection. Design: Multicentre cross-sectional study. Settings: Infectious Diseases or Internal Medicine outpatient Clinics of 3 hospitals in the Basque Country. Participants: During a 3 month period, patients with the following inclusion criteria were randomly selected: HIV infection, age>18years, antiretroviral treatment (ART) for at least 6months, and no changes in ART in the previous 4weeks. A total of 224 patients (of the 225 expected) were included. Measurements: Data were collected using a form, and include, epidemiological and anthropometric data, data related to HIV infection, comorbidities, current therapies, and adverse effects. Results: Of the 224 patients, 95.5% had at least one comorbidity, the most common being HCV infection (51.3%), dyslipidaemia (37.9%), diabetes mellitus or impaired fasting glucose (21.9%), and hypertension (21.9%). A total of 155 patients (69.2%) were taking concomitant medication: anxiolytics (21.4%), antihypertensives (19.6%), proton pump inhibitors (17.9%), statins (17%), and antidepressants (16.5%). Adverse effects (AE) were observed in 62.9% of subjects, the most common being, changes in body fat distribution (32.6%) and gastrointestinal (24.1%). Conclusions: Patients with HIV infection are getting older, with more comorbidities, with very frequent use of concomitant treatments, and high number of adverse effects. This requires a multidisciplinary approach and a coordinated effort within the Primary Care setting. |
MeSH term(s) | Adult ; Aged ; Cross-Sectional Studies ; Drug-Related Side Effects and Adverse Reactions ; Female ; HIV Infections/complications ; HIV Infections/drug therapy ; Humans ; Male ; Middle Aged ; Polypharmacy ; Young Adult |
Language | Spanish |
Publishing date | 2016-10-05 |
Publishing country | Spain |
Document type | Journal Article ; Multicenter Study ; Observational Study |
ZDB-ID | 1200787-0 |
ISSN | 1578-1275 ; 0212-6567 |
ISSN (online) | 1578-1275 |
ISSN | 0212-6567 |
DOI | 10.1016/j.aprim.2016.06.010 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
Zs.A 4054: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.