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  1. Article ; Online: Performing Computed Tomography Instead of Invasive Coronary Angiography: Sex Effects in Patients With Suspected CAD.

    Bosserdt, Maria / Feger, Sarah / Rief, Matthias / Preuß, Daniel / Ibes, Paolo / Martus, Peter / Kofoed, Klaus F / Laule, Michael / Perez, Ivan / Dewey, Marc

    JACC. Cardiovascular imaging

    2019  Volume 13, Issue 3, Page(s) 888–889

    MeSH term(s) Computed Tomography Angiography/adverse effects ; Coronary Angiography/adverse effects ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/mortality ; Coronary Artery Disease/therapy ; Female ; Health Status Disparities ; Humans ; Male ; Predictive Value of Tests ; Prognosis ; Risk Factors ; Sex Factors
    Language English
    Publishing date 2019-12-18
    Publishing country United States
    Document type Comparative Study ; Letter ; Randomized Controlled Trial
    ZDB-ID 2491503-8
    ISSN 1876-7591 ; 1936-878X
    ISSN (online) 1876-7591
    ISSN 1936-878X
    DOI 10.1016/j.jcmg.2019.10.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Clinical pre-test probability for obstructive coronary artery disease: insights from the European DISCHARGE pilot study.

    Feger, Sarah / Ibes, Paolo / Napp, Adriane E / Lembcke, Alexander / Laule, Michael / Dreger, Henryk / Bokelmann, Björn / Davis, Gershan K / Roditi, Giles / Diez, Ignacio / Schröder, Stephen / Plank, Fabian / Maurovich-Horvat, Pal / Vidakovic, Radosav / Veselka, Josef / Ilnicka-Suckiel, Malgorzata / Erglis, Andrejs / Benedek, Teodora / Rodriguez-Palomares, José /
    Saba, Luca / Kofoed, Klaus F / Gutberlet, Matthias / Ađić, Filip / Pietilä, Mikko / Faria, Rita / Vaitiekiene, Audrone / Dodd, Jonathan D / Donnelly, Patrick / Francone, Marco / Kepka, Cezary / Ruzsics, Balazs / Müller-Nordhorn, Jacqueline / Schlattmann, Peter / Dewey, Marc

    European radiology

    2020  Volume 31, Issue 3, Page(s) 1471–1481

    Abstract: Objectives: To test the accuracy of clinical pre-test probability (PTP) for prediction of obstructive coronary artery disease (CAD) in a pan-European setting.: Methods: Patients with suspected CAD and stable chest pain who were clinically referred ... ...

    Abstract Objectives: To test the accuracy of clinical pre-test probability (PTP) for prediction of obstructive coronary artery disease (CAD) in a pan-European setting.
    Methods: Patients with suspected CAD and stable chest pain who were clinically referred for invasive coronary angiography (ICA) or computed tomography (CT) were included by clinical sites participating in the pilot study of the European multi-centre DISCHARGE trial. PTP of CAD was determined using the Diamond-Forrester (D+F) prediction model initially introduced in 1979 and the updated D+F model from 2011. Obstructive coronary artery disease (CAD) was defined by one at least 50% diameter coronary stenosis by both CT and ICA.
    Results: In total, 1440 patients (654 female, 786 male) were included at 25 clinical sites from May 2014 until July 2017. Of these patients, 725 underwent CT, while 715 underwent ICA. Both prediction models overestimated the prevalence of obstructive CAD (31.7%, 456 of 1440 patients, PTP: initial D+F 58.9% (28.1-90.6%), updated D+F 47.3% (34.2-59.9%), both p < 0.001), but overestimation of disease prevalence was higher for the initial D+F (p < 0.001). The discriminative ability was higher for the updated D+F 2011 (AUC of 0.73 95% confidence interval [CI] 0.70-0.76 versus AUC of 0.70 CI 0.67-0.73 for the initial D+F; p < 0.001; odds ratio (or) 1.55 CI 1.29-1.86, net reclassification index 0.11 CI 0.05-0.16, p < 0.001).
    Conclusions: Clinical PTP calculation using the initial and updated D+F prediction models relevantly overestimates the actual prevalence of obstructive CAD in patients with stable chest pain clinically referred for ICA and CT suggesting that further refinements to improve clinical decision-making are needed.
    Trial registration: https://www.clinicaltrials.gov/ct2/show/NCT02400229 KEY POINTS: • Clinical pre-test probability calculation using the initial and updated D+F model overestimates the prevalence of obstructive CAD identified by ICA and CT. • Overestimation of disease prevalence is higher for the initial D+F compared with the updated D+F. • Diagnostic accuracy of PTP assessment varies strongly between different clinical sites throughout Europe.
    MeSH term(s) Computed Tomography Angiography ; Coronary Angiography ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/epidemiology ; Coronary Stenosis/diagnostic imaging ; Coronary Stenosis/epidemiology ; Europe ; Female ; Humans ; Male ; Patient Discharge ; Pilot Projects ; Predictive Value of Tests ; Risk Assessment ; Risk Factors
    Language English
    Publishing date 2020-09-09
    Publishing country Germany
    Document type Clinical Trial ; Journal Article
    ZDB-ID 1085366-2
    ISSN 1432-1084 ; 0938-7994 ; 1613-3749
    ISSN (online) 1432-1084
    ISSN 0938-7994 ; 1613-3749
    DOI 10.1007/s00330-020-07175-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain.

    Rieckmann, Nina / Neumann, Konrad / Feger, Sarah / Ibes, Paolo / Napp, Adriane / Preuß, Daniel / Dreger, Henryk / Feuchtner, Gudrun / Plank, Fabian / Suchánek, Vojtěch / Veselka, Josef / Engstrøm, Thomas / Kofoed, Klaus F / Schröder, Stephen / Zelesny, Thomas / Gutberlet, Matthias / Woinke, Michael / Maurovich-Horvat, Pál / Merkely, Béla /
    Donnelly, Patrick / Ball, Peter / Dodd, Jonathan D / Hensey, Mark / Loi, Bruno / Saba, Luca / Francone, Marco / Mancone, Massimo / Berzina, Marina / Erglis, Andrejs / Vaitiekiene, Audrone / Zajanckauskiene, Laura / Harań, Tomasz / Suckiel, Malgorzata Ilnicka / Faria, Rita / Gama-Ribeiro, Vasco / Benedek, Imre / Rodean, Ioana / Adjić, Filip / Čemerlić Adjić, Nada / Rodriguez-Palomares, José / Garcia Del Blanco, Bruno / Brooksbank, Katriona / Collison, Damien / Davis, Gershan / Thwaite, Erica / Knuuti, Juhani / Saraste, Antti / Kępka, Cezary / Kruk, Mariusz / Benedek, Theodora / Ratiu, Mihaela / Neskovic, Aleksandar N / Vidakovic, Radosav / Diez, Ignacio / Lecumberri, Iñigo / Fisher, Michael / Ruzsics, Balazs / Hollingworth, William / Gutiérrez-Ibarluzea, Iñaki / Dewey, Marc / Müller-Nordhorn, Jacqueline

    Health and quality of life outcomes

    2020  Volume 18, Issue 1, Page(s) 140

    Abstract: Background: Health-related quality of life (HRQoL) is impaired in patients with stable angina but patients often present with other forms of chest pain. The aim of this study was to compare the pre-diagnostic HRQoL in patients with suspected coronary ... ...

    Abstract Background: Health-related quality of life (HRQoL) is impaired in patients with stable angina but patients often present with other forms of chest pain. The aim of this study was to compare the pre-diagnostic HRQoL in patients with suspected coronary artery disease (CAD) according to angina type, gender, and presence of obstructive CAD.
    Methods: From the pilot study for the European DISCHARGE trial, we analysed data from 24 sites including 1263 patients (45.9% women, 61.1 ± 11.3 years) who were clinically referred for invasive coronary angiography (ICA; 617 patients) or coronary computed tomography angiography (CTA; 646 patients). Prior to the procedures, patients completed HRQoL questionnaires: the Short Form (SF)-12v2, the EuroQoL (EQ-5D-3 L) and the Hospital Anxiety and Depression Scale.
    Results: Fifty-five percent of ICA and 35% of CTA patients had typical angina, 23 and 33% had atypical angina, 18 and 28% had non-anginal chest discomfort and 5 and 5% had other chest discomfort, respectively. Patients with typical angina had the poorest physical functioning compared to the other angina groups (SF-12 physical component score; 41.2 ± 8.8, 43.3 ± 9.1, 46.2 ± 9.0, 46.4 ± 11.4, respectively, all age and gender-adjusted p < 0.01), and highest anxiety levels (8.3 ± 4.1, 7.5 ± 4.1, 6.5 ± 4.0, 4.7 ± 4.5, respectively, all adjusted p < 0.01). On all other measures, patients with typical or atypical angina had lower HRQoL compared to the two other groups (all adjusted p < 0.05). HRQoL did not differ between patients with and without obstructive CAD while women had worse HRQoL compared with men, irrespective of age and angina type.
    Conclusions: Prior to a diagnostic procedure for stable chest pain, HRQoL is associated with chest pain characteristics, but not with obstructive CAD, and is significantly lower in women.
    Trial registration: Clinicaltrials.gov, NCT02400229.
    MeSH term(s) Aged ; Angina Pectoris/classification ; Angina Pectoris/diagnosis ; Angina Pectoris/physiopathology ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/physiopathology ; Female ; Humans ; Male ; Middle Aged ; Pilot Projects ; Quality of Life ; Sex Distribution ; Surveys and Questionnaires
    Language English
    Publishing date 2020-05-14
    Publishing country England
    Document type Journal Article ; Multicenter Study ; Pragmatic Clinical Trial
    ISSN 1477-7525
    ISSN (online) 1477-7525
    DOI 10.1186/s12955-020-01312-4
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  4. Article ; Online: Correction to: Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain.

    Rieckmann, Nina / Neumann, Konrad / Feger, Sarah / Ibes, Paolo / Napp, Adriane / Preuß, Daniel / Dreger, Henryk / Feuchtner, Gudrun / Plank, Fabian / Suchánek, Vojtěch / Veselka, Josef / Engstrøm, Thomas / Kofoed, Klaus F / Schröder, Stephen / Zelesny, Thomas / Gutberlet, Matthias / Woinke, Michael / Maurovich-Horvat, Pál / Merkely, Béla /
    Donnelly, Patrick / Ball, Peter / Dodd, Jonathan D / Hensey, Mark / Loi, Bruno / Saba, Luca / Francone, Marco / Mancone, Massimo / Berzina, Marina / Erglis, Andrejs / Vaitiekiene, Audrone / Zajanckauskiene, Laura / Harań, Tomasz / Suckiel, Malgorzata Ilnicka / Faria, Rita / Gama-Ribeiro, Vasco / Benedek, Imre / Rodean, Ioana / Adjić, Filip / Adjić, Nada Čemerlić / Rodriguez-Palomares, José / Del Blanco, Bruno Garcia / Brooksbank, Katriona / Collison, Damien / Davis, Gershan / Thwaite, Erica / Knuuti, Juhani / Saraste, Antti / Kępka, Cezary / Kruk, Mariusz / Benedek, Theodora / Ratiu, Mihaela / Neskovic, Aleksandar N / Vidakovic, Radosav / Diez, Ignacio / Lecumberri, Iñigo / Fisher, Michael / Ruzsics, Balazs / Hollingworth, William / Gutiérrez-Ibarluzea, Iñaki / Dewey, Marc / Müller-Nordhorn, Jacqueline

    Health and quality of life outcomes

    2020  Volume 18, Issue 1, Page(s) 205

    Abstract: An amendment to this paper has been published and can be accessed via the original article. ...

    Abstract An amendment to this paper has been published and can be accessed via the original article.
    Keywords covid19
    Language English
    Publishing date 2020-06-29
    Publishing country England
    Document type Journal Article ; Published Erratum
    ISSN 1477-7525
    ISSN (online) 1477-7525
    DOI 10.1186/s12955-020-01443-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Correction to: Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain

    Rieckmann, Nina / Neumann, Konrad / Feger, Sarah / Ibes, Paolo / Napp, Adriane / Preuß, Daniel / Dreger, Henryk / Feuchtner, Gudrun / Plank, Fabian / Suchánek, Vojtech / Veselka, Josef / Engstrøm, Thomas / Kofoed, Klaus F / Schröder, Stephen / Zelesny, Thomas / Gutberlet, Matthias / Woinke, Michael / Maurovich-Horvat, Pál / Merkely, Béla /
    Donnelly, Patrick / Ball, Peter / Dodd, Jonathan D / Hensey, Mark / Loi, Bruno / Saba, Luca / Francone, Marco / Mancone, Massimo / Berzina, Marina / Erglis, Andrejs / Vaitiekiene, Audrone / Zajanckauskiene, Laura / Haran, Tomasz / Suckiel, Malgorzata Ilnicka / Faria, Rita / Gama-Ribeiro, Vasco / Benedek, Imre / Rodean, Ioana / Adjic, Filip / Adjic, Nada Cemerlic / Rodriguez-Palomares, José / Del Blanco, Bruno Garcia / Brooksbank, Katriona / Collison, Damien / Davis, Gershan / Thwaite, Erica / Knuuti, Juhani / Saraste, Antti / Kepka, Cezary / Kruk, Mariusz / Benedek, Theodora

    Health Qual Life Outcomes

    Abstract: An amendment to this paper has been published and can be accessed via the original article. ...

    Abstract An amendment to this paper has been published and can be accessed via the original article.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32600467
    Database COVID19

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