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Article ; Online: Two case reports using a proposed oral risk assessment tool for older people near the end of life.

Tanaka, Kumi / Kikutani, Takeshi / Tohara, Takashi / Sato, Shiho / Ichikawa, Yoko / Takahashi, Noriaki / Tamura, Fumiyo

Clinical and experimental dental research

2022 Volume 8, Issue 2, Page(s) 600–609

Abstract: Objectives: We developed a prototype technique that expresses the need for intervention and the effectiveness of the treatment when "not being at risk of injury to the oral cavity or to general health" due to the presence of teeth or prostheses is taken ...

Abstract	Objectives: We developed a prototype technique that expresses the need for intervention and the effectiveness of the treatment when "not being at risk of injury to the oral cavity or to general health" due to the presence of teeth or prostheses is taken as the desired outcome of dental treatment for older people near the end of life. The objective of this study was to use the prototype risk assessment matrix to identify the risk for each patient according to their course and show the effectiveness of treatment. Material and methods: We produced a prototype Dental Risk Map (Dental R-map) based on the risk map method of risk management. Risk is classified into three levels according to the level of tolerability: (A) Risk for which watchful waiting should be included among measures to be considered; (B) risk for which intervention should be considered; or (C) risk requiring urgent intervention. Results: We report the application of this technique to two men in their 80s. Both were assessed as risk tolerability Level C, requiring immediate intervention. Dental treatment eliminated this risk in one and reduced it to Level B in the other. Conclusions: We developed the prototype Dental R-map to identify oral risks and indicate the need for intervention to address these risks and the effectiveness of treatment for older people near the end of life. We used the Dental R-map for two patients and successfully avoided oral risks that might cause physical injury in both cases until their deaths.
MeSH term(s)	Aged ; Death ; Humans ; Male ; Risk Assessment
Language	English
Publishing date	2022-03-29
Publishing country	United States
Document type	Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2829558-4
ISSN	2057-4347 ; 2057-4347
ISSN (online)	2057-4347
ISSN	2057-4347
DOI	10.1002/cre2.566
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Article ; Online: Co-ingestion of traditional Japanese barley mixed rice (Mugi gohan) with yam paste in healthy Japanese adults decreases postprandial glucose and insulin secretion in a randomized crossover trial.

Matsuoka, Tsubasa / Yamaji, Ayako / Kurosawa, Chihiro / Shinohara, Manabu / Takayama, Ichiro / Nakagomi, Hiromi / Izumi, Keiko / Ichikawa, Yoko / Hariya, Natsuyo / Mochizuki, Kazuki

Asia Pacific journal of clinical nutrition

2023 Volume 32, Issue 1, Page(s) 40–47

Abstract: Background and objectives: Barley mixed rice, "Mugi gohan," is traditionally eaten with yam paste in Japan. Both ingredients contain dietary fiber and reportedly reduce postprandial hyperglycemia. However, evidence supporting the benefits of combining ... ...

Abstract	Background and objectives: Barley mixed rice, "Mugi gohan," is traditionally eaten with yam paste in Japan. Both ingredients contain dietary fiber and reportedly reduce postprandial hyperglycemia. However, evidence supporting the benefits of combining barley mixed rice with yam paste is limited. In this study, we evaluated whether ingesting a combination of barley mixed rice and yam paste affected postprandial blood glucose concentration and insulin secretion. Methods and study design: This study followed an open-label, randomized controlled crossover design, following the unified protocol of the Japanese Association for the Study of Glycemic Index. Fourteen healthy subjects each consumed four different test meals: white rice only, white rice with yam paste, barley mixed rice, and barley mixed rice with yam paste. We measured their postprandial blood glucose and insulin concentrations after every meal, and we calculated the area under curve for glucose and insulin. Results: Participants had significantly reduced area under curve for glucose and insulin after eating barley mixed rice with yam paste compared to when they ate white rice only. Participants had similar area under curve for glucose and insulin after eating barley mixed rice only, or eating white rice with yam paste. Participants had lower blood glucose concentrations 15 min after eating barley mixed rice only, whilst eating white rice with yam paste did not maintain lower blood glucose after 15 min. Conclusions: Eating barley mixed rice with yam paste decreases postprandial blood glucose concentrations and reduces insulin secretion.
MeSH term(s)	Adult ; Humans ; Blood Glucose ; Cross-Over Studies ; Dioscorea ; East Asian People ; Eating ; Hordeum ; Insulin ; Insulin Secretion ; Meals ; Oryza ; Postprandial Period
Chemical Substances	Blood Glucose ; Insulin
Language	English
Publishing date	2023-03-30
Publishing country	Australia
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	1460012-2
ISSN	1440-6047 ; 0964-7058
ISSN (online)	1440-6047
ISSN	0964-7058
DOI	10.6133/apjcn.202303_32(1).0007
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Article: Effect of food intake on the ventilatory response to increasing core temperature during exercise

Hayashi, Keiji / Ito, Nozomi / Ichikawa, Yoko / Suzuki, Yuichi

Applied physiology, nutrition and metabolism. 2019, v. 44, no. 1

2019

Abstract: Food intake increases metabolism and body temperature, which may in turn influence ventilatory responses. Our aim was to assess the effect of food intake on ventilatory sensitivity to rising core temperature during exercise. Nine healthy male subjects ... ...

Abstract	Food intake increases metabolism and body temperature, which may in turn influence ventilatory responses. Our aim was to assess the effect of food intake on ventilatory sensitivity to rising core temperature during exercise. Nine healthy male subjects exercised on a cycle ergometer at 50% of peak oxygen uptake in sessions with and without prior food intake. Ventilatory sensitivity to rising core temperature was defined by the slopes of regression lines relating ventilatory parameters to core temperature. Mean skin temperature, mean body temperature (calculated from esophageal temperature and mean skin temperature), oxygen uptake, carbon dioxide elimination, minute ventilation, alveolar ventilation, and tidal volume (VT) were all significantly higher at baseline in sessions with food intake than without food intake. During exercise, esophageal temperature, mean skin temperature, mean body temperature, carbon dioxide elimination, and end-tidal CO2 pressure were all significantly higher in sessions with food intake than without it. By contrast, ventilatory parameters did not differ between sessions with and without food intake, with the exception of VT during the first 5 min of exercise. The ventilatory sensitivities to rising core temperature also did not differ, with the exception of an early transient effect on VT. Food intake increases body temperature before and during exercise. Other than during the first 5 min of exercise, food intake does not affect ventilatory parameters during exercise, despite elevation of both body temperature and metabolism. Thus, with the exception of an early transient effect on VT, ventilatory sensitivity to rising core temperature is not affected by food intake.
Keywords	body temperature ; breathing ; carbon dioxide ; exercise ; food intake ; males ; metabolism ; oxygen ; peak oxygen uptake ; skin temperature ; tidal volume
Language	English
Size	p. 22-30.
Publishing place	NRC Research Press
Document type	Article
ZDB-ID	2236708-1
ISSN	1715-5320 ; 1715-5312
ISSN (online)	1715-5320
ISSN	1715-5312
DOI	10.1139/apnm-2018-0069
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Article: Changes in peripheral inflammation-related gene expression by postprandial glycemic response in healthy Japanese men

Honma, Kazue / Jin, Fangru / Tonaka, Ryota / Sabashi, Toru / Otsuki, Naoko / Ichikawa, Yoko / Goda, Toshinao

Nutrition. 2021 Apr., v. 84

2021

Abstract: Continuous postprandial hyperglycemia is associated with the onset of cardiovascular disease. In recent years, the mRNA expression of inflammation-related genes in peripheral blood leukocytes has been shown to be induced by an increase in blood glucose ... ...

Abstract	Continuous postprandial hyperglycemia is associated with the onset of cardiovascular disease. In recent years, the mRNA expression of inflammation-related genes in peripheral blood leukocytes has been shown to be induced by an increase in blood glucose levels. The aim of this study was to investigate differences in the expression of inflammation-related genes in peripheral blood leukocytes in response to an increase in blood glucose from individuals who consumed two kinds of breakfast meals with different glycemic indexes (GIs).Twenty healthy Japanese men 40 to 70 y of age were given low- or high-GI meals for breakfast for 14 d. Clinical examinations were performed on days 7 and 14. Their blood glucose levels and insulin concentrations were measured from before breakfast ingestion to 120 min after. Additionally, using the blood obtained before and 120 min after breakfast, the mRNA expression levels of inflammation-related genes in peripheral leukocytes were measured.The blood glucose levels were significantly lower in the low-GI meal intake group at 30, 60, and 120 min after breakfast than in the high-GI meal intake group. The intake of high-GI meals for 6 d led to an increase in the mRNA levels of interleukin-1β, S100A4, and CD18 compared with the period of low-GI meals.The intake of a low-GI breakfast for 1 wk in healthy Japanese men resulted in lower postprandial blood glucose and insulin levels, which were accompanied by a reduced expression of inflammation-related genes in peripheral blood leukocytes.
Keywords	blood glucose ; breakfast ; cardiovascular diseases ; gene expression ; glycemic effect ; hyperglycemia ; ingestion ; insulin
Language	English
Dates of publication	2021-04
Publishing place	Elsevier Inc.
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	639259-3
ISSN	1873-1244 ; 0899-9007
ISSN (online)	1873-1244
ISSN	0899-9007
DOI	10.1016/j.nut.2020.111026
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Article ; Online: Effect of chest compression with kneeling on the bed in clinical situations.

Hasegawa, Tomoyuki / Okane, Ritsu / Ichikawa, Yoko / Inukai, Sayuri / Saito, Shin

Japan journal of nursing science : JJNS

2020 Volume 17, Issue 2, Page(s) e12314

Abstract: Aim: Cardiopulmonary resuscitation is vital for survival after cardiac arrest, and chest compressions are an important aspect of this. When performing chest compression in a hospital setting, the rescuer often has to kneel on the bed to overcome ... ...

Abstract	Aim: Cardiopulmonary resuscitation is vital for survival after cardiac arrest, and chest compressions are an important aspect of this. When performing chest compression in a hospital setting, the rescuer often has to kneel on the bed to overcome inconvenient differences in height between the rescuer and the bed. However, as yet no study has evaluated the quality of chest compressions in this position. The aim of this study was to examine the impact on the quality of chest compressions while kneeling on the bed. Methods: Fifteen female students performed 2-min chest compressions on a manikin placed on the floor and a bed. Measurement parameters included compression depth, heart rate, integrated electromyogram, and a visual analog scale. The parameters were measured every 30 s and were statistically compared between the conditions. Results: Compression depth at 30, 60, 90, and 120 s differed significantly between the conditions. Heart rate values at 150 and 210 s of recovery significantly differed between the conditions. Integrated electromyogram values for the trapezius, rectus femoris, and biceps femoris differed between the floor and bed conditions during 2-min chest compressions, whereas the external oblique muscle significantly differed at 60 and 120 s. Visual analog scales for fatigue, effectiveness, and stability significantly differed between the conditions. Conclusion: Kneeling on the bed does not enable grounding of the toe, causing the upper body to be unstable and limiting generation of the power required for chest compression. Our results suggest that rotation every minute is necessary to maintain effective cardiopulmonary resuscitation while kneeling on the bed.
MeSH term(s)	Cardiopulmonary Resuscitation ; Fatigue ; Female ; Heart Rate ; Humans ; Male ; Manikins ; Posture ; Young Adult
Language	English
Publishing date	2020-01-19
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2156618-5
ISSN	1742-7924 ; 1742-7932
ISSN (online)	1742-7924
ISSN	1742-7932
DOI	10.1111/jjns.12314
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Article ; Online: Effect of food intake on the ventilatory response to increasing core temperature during exercise.

Hayashi, Keiji / Ito, Nozomi / Ichikawa, Yoko / Suzuki, Yuichi

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme

2018 Volume 44, Issue 1, Page(s) 22–30

Abstract	Food intake increases metabolism and body temperature, which may in turn influence ventilatory responses. Our aim was to assess the effect of food intake on ventilatory sensitivity to rising core temperature during exercise. Nine healthy male subjects exercised on a cycle ergometer at 50% of peak oxygen uptake in sessions with and without prior food intake. Ventilatory sensitivity to rising core temperature was defined by the slopes of regression lines relating ventilatory parameters to core temperature. Mean skin temperature, mean body temperature (calculated from esophageal temperature and mean skin temperature), oxygen uptake, carbon dioxide elimination, minute ventilation, alveolar ventilation, and tidal volume (V
MeSH term(s)	Adaptation, Physiological ; Adult ; Bicycling ; Body Temperature Regulation ; Eating ; Energy Metabolism ; Exercise/physiology ; Healthy Volunteers ; Humans ; Lung/physiology ; Male ; Muscle Contraction ; Muscle, Skeletal/metabolism ; Oxygen Consumption ; Pulmonary Ventilation ; Skin Temperature ; Time Factors ; Young Adult
Language	English
Publishing date	2018-06-26
Publishing country	Canada
Document type	Journal Article
ZDB-ID	2236708-1
ISSN	1715-5320 ; 1715-5312
ISSN (online)	1715-5320
ISSN	1715-5312
DOI	10.1139/apnm-2018-0069
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Article ; Online: Neonatal skin dysbiosis to infantile atopic dermatitis: Mitigating effects of skin care.

Aoyama, Reika / Nakagawa, Seitaro / Ichikawa, Yoko / Inohara, Naohiro / Yamazaki, Yuriko / Ito, Tomoka / Sugihira, Takashi / Kono, Michihiro / Akiyama, Masashi / Takahashi, Hiroki / Takaya, Akiko / Ichikawa, Fumitaka / Nakano, Taiji / Tanaka, Seiko / Koyano, Yutaka / Fujimoto, Manabu / Núñez, Gabriel / Shimojo, Naoki / Nakamura, Yuumi

Allergy

2024

Language	English
Publishing date	2024-03-09
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	391933-x
ISSN	1398-9995 ; 0105-4538
ISSN (online)	1398-9995
ISSN	0105-4538
DOI	10.1111/all.16095
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Article ; Online: Problems experienced when swallowing solid oral dosage forms in older Japanese patients with dysphagia: A cross-sectional study.

Tanaka, Kumi / Kikutani, Takeshi / Tamura, Fumiyo / Sato, Shiho / Komagata, Yuka / Shibasaki, Ikumi / Tomioka, Kosei / Ichikawa, Yoko / Shiobara, Yuichiro / Sato, Takanobu / Tohara, Takashi

Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry

2023 Volume 44, Issue 1, Page(s) 214–220

Abstract: Aims: We aimed to assess the difficulty in taking solid oral dosage forms (SODFs) among older people with dysphagia and clarify the relationship between difficulty in swallowing SODFs and swallowing function.: Methods and results: Outpatients from a ... ...

Abstract	Aims: We aimed to assess the difficulty in taking solid oral dosage forms (SODFs) among older people with dysphagia and clarify the relationship between difficulty in swallowing SODFs and swallowing function. Methods and results: Outpatients from a dysphagia clinic aged ≥65 years were asked yes-or-no questions about the applicability of eight items regarding difficulty in taking SODFs. Additionally, a videofluorographic swallowing study (VFSS) was performed to assess their swallowing function. The Kruskal-Wallis test and Spearman's rank correlation coefficient were used to analyze the relationship between difficulty in taking SODFs and swallowing function. Results: Among the 93 participants, the average number of SODFs consumed was 5.8 ± 3.1. In the questionnaire, the average number of "yes" answers was 2.2 ± 2.2, and 65 patients (71.0%) answered "yes" to at least one question. Additionally, no significant relationship was observed between the perceived difficulty in swallowing SODFs and VFSS findings. Conclusion: Approximately 70% of participants reported subjective difficulty in taking SODFs, showing that patients uniformly reported perceived difficulty in taking SODFs regardless of actual swallowing function. The results of this study suggest that patients must be questioned thoroughly about their SODFs use, regardless of the objective severity of their dysphagia.
MeSH term(s)	Humans ; Aged ; Deglutition ; Deglutition Disorders ; Cross-Sectional Studies ; Japan ; Surveys and Questionnaires
Language	English
Publishing date	2023-04-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	604118-8
ISSN	1754-4505 ; 0275-1879
ISSN (online)	1754-4505
ISSN	0275-1879
DOI	10.1111/scd.12853
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Article ; Online: Changes in peripheral inflammation-related gene expression by postprandial glycemic response in healthy Japanese men.

Honma, Kazue / Jin, Fangru / Tonaka, Ryota / Sabashi, Toru / Otsuki, Naoko / Ichikawa, Yoko / Goda, Toshinao

Nutrition (Burbank, Los Angeles County, Calif.)

2020 Volume 84, Page(s) 111026

Abstract: Objectives: Continuous postprandial hyperglycemia is associated with the onset of cardiovascular disease. In recent years, the mRNA expression of inflammation-related genes in peripheral blood leukocytes has been shown to be induced by an increase in ... ...

Abstract	Objectives: Continuous postprandial hyperglycemia is associated with the onset of cardiovascular disease. In recent years, the mRNA expression of inflammation-related genes in peripheral blood leukocytes has been shown to be induced by an increase in blood glucose levels. The aim of this study was to investigate differences in the expression of inflammation-related genes in peripheral blood leukocytes in response to an increase in blood glucose from individuals who consumed two kinds of breakfast meals with different glycemic indexes (GIs). Methods: Twenty healthy Japanese men 40 to 70 y of age were given low- or high-GI meals for breakfast for 14 d. Clinical examinations were performed on days 7 and 14. Their blood glucose levels and insulin concentrations were measured from before breakfast ingestion to 120 min after. Additionally, using the blood obtained before and 120 min after breakfast, the mRNA expression levels of inflammation-related genes in peripheral leukocytes were measured. Results: The blood glucose levels were significantly lower in the low-GI meal intake group at 30, 60, and 120 min after breakfast than in the high-GI meal intake group. The intake of high-GI meals for 6 d led to an increase in the mRNA levels of interleukin-1β, S100A4, and CD18 compared with the period of low-GI meals. Conclusion: The intake of a low-GI breakfast for 1 wk in healthy Japanese men resulted in lower postprandial blood glucose and insulin levels, which were accompanied by a reduced expression of inflammation-related genes in peripheral blood leukocytes.
MeSH term(s)	Blood Glucose ; Cross-Over Studies ; Gene Expression ; Glycemic Index ; Humans ; Inflammation/genetics ; Insulin ; Japan ; Male ; Postprandial Period
Chemical Substances	Blood Glucose ; Insulin
Language	English
Publishing date	2020-09-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	639259-3
ISSN	1873-1244 ; 0899-9007
ISSN (online)	1873-1244
ISSN	0899-9007
DOI	10.1016/j.nut.2020.111026
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Article ; Online: COVID-19 Infection-Related Weight Loss Decreases Eating/Swallowing Function in Schizophrenic Patients.

Kikutani, Takeshi / Ichikawa, Yoko / Kitazume, Eri / Mizukoshi, Arato / Tohara, Takashi / Takahashi, Noriaki / Tamura, Fumiyo / Matsutani, Manami / Onishi, Junko / Makino, Eiichiro

Nutrients

2021 Volume 13, Issue 4

Abstract: Background: In older people with psychoneurological diseases, COVID-19 infection may be associated with a risk of developing or exacerbating dysphagia. The aim of the present study was to examine the relationship between eating/swallowing function and ... ...

Abstract	Background: In older people with psychoneurological diseases, COVID-19 infection may be associated with a risk of developing or exacerbating dysphagia. The aim of the present study was to examine the relationship between eating/swallowing function and COVID-19 infection. Methods: Subjects were 44 inpatients with confirmed COVID-19 infection being treated for schizophrenia in a psychiatric ward. Eating function was assessed using the Food Intake Level Scale (FILS) before and after infection. We also evaluated age, comorbidities, COVID-19 hospital stay, obesity index, weight loss rate, and chlorpromazine equivalent. Results: Subjects had a mean age of 68.86 years. Pre-infection, 20 subjects had a FILS score of 7-9 (presence of eating/swallowing disorder) and 24 subjects had a score of 10 (normal). Eating function after infection resolution showed decreasing FILS score compared to that before infection in 14 subjects (74.14 years). Six subjects (79.3 years) transitioned from oral feeding to parenteral feeding. A ≥ 10% weight loss during infection treatment was significantly associated with decreased eating function and a transition to parenteral feeding. Chlorpromazine equivalents, comorbidities, and number of days of hospitalization showed no associations with decreased eating function. Conclusions: Preventing malnutrition during treatment for COVID-19 infection is important for improving post-infection life prognosis and maintaining quality of life (QOL).
MeSH term(s)	Aged ; COVID-19/complications ; COVID-19/physiopathology ; COVID-19/psychology ; Deglutition Disorders/etiology ; Deglutition Disorders/physiopathology ; Deglutition Disorders/psychology ; Eating/physiology ; Eating/psychology ; Feeding and Eating Disorders/etiology ; Feeding and Eating Disorders/physiopathology ; Feeding and Eating Disorders/psychology ; Female ; Humans ; Male ; Middle Aged ; Nutritional Status ; Schizophrenia/complications ; Schizophrenia/virology ; Weight Loss
Language	English
Publishing date	2021-03-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu13041113
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