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  1. Article: Infective endocarditis by Abiotrophia defectiva presenting as acute coronary syndrome.

    Jacob, Aneeta / Idikula, Mercy John

    The National medical journal of India

    2023  Volume 35, Issue 5, Page(s) 318

    MeSH term(s) Humans ; Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/drug therapy ; Endocarditis, Bacterial/diagnosis ; Endocarditis, Bacterial/drug therapy ; Endocarditis/drug therapy ; Abiotrophia ; Anti-Bacterial Agents/therapeutic use
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-05-11
    Publishing country India
    Document type Journal Article
    ZDB-ID 645116-0
    ISSN 0970-258X
    ISSN 0970-258X
    DOI 10.25259/NMJI_483_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Brain tuberculoma: a 52-year-old woman case report.

    Shankar, Gokul S / Nair, Sreeja / Jacob, Teena / Idikula, Mercy John

    Access microbiology

    2023  Volume 5, Issue 10

    Abstract: Introduction: One of the most serious extrapulmonary type of tuberculosis that affects people under the age of 40 is brain tuberculoma. They are space-occupying masses of granulomatous tissue that result from hematogenous spread from a distant focus of ... ...

    Abstract Introduction: One of the most serious extrapulmonary type of tuberculosis that affects people under the age of 40 is brain tuberculoma. They are space-occupying masses of granulomatous tissue that result from hematogenous spread from a distant focus of tuberculous infection by
    Case report: The authors present a case report of a 52-year-old diabetic woman, who presented to the Emergency Department of a tertiary care hospital and was diagnosed with brain tuberculomas with a brain biopsy. Brain tuberculomas are rare and could be overlooked. Therefore, this is an important consideration in cases with higher suspicions, given the rapid decline in patient condition.
    Conclusion: Due to their rarity, ambiguous symptoms, and radiographic characteristics, intracranial tuberculomas continue to provide a clinical challenge and must always be considered in the differential diagnosis of cerebral space occupying lesions. As CSF may not yield positivity for both CBNAAT and smear examination, a brain biopsy specimen for culture should always be kept in mind for detecting tuberculoma and initiating anti-tubercular treatment at the earliest.
    Language English
    Publishing date 2023-10-16
    Publishing country England
    Document type Case Reports
    ISSN 2516-8290
    ISSN (online) 2516-8290
    DOI 10.1099/acmi.0.000634.v4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Incidence, prevalence, clinical features, and outcomes of COVID-19 in persons with cystic fibrosis: a systematic review protocol.

    Antony, Sherly / Vargese, Saritha Susan / Idikula, Mercy John / Cherian, Carol Sara / Mathew, Elsheba / Green, Heidi / Fernandez, Ritin

    JBI evidence synthesis

    2022  Volume 20, Issue 11, Page(s) 2721–2726

    Abstract: Objective: The objective of this review is to determine the incidence and prevalence, clinical features, and outcomes of COVID-19 in persons with cystic fibrosis.: Introduction: Cystic fibrosis, predominantly a chronic respiratory illness, has long ... ...

    Abstract Objective: The objective of this review is to determine the incidence and prevalence, clinical features, and outcomes of COVID-19 in persons with cystic fibrosis.
    Introduction: Cystic fibrosis, predominantly a chronic respiratory illness, has long been known to be fatal with concomitant bacterial or viral infections. Consequently, the effects of COVID-19 on this protracted disease need to be understood, especially since the major manifestations affect the respiratory system. Hence, this review aims to examine the burden, clinical features, and outcomes of COVID-19 on individuals with cystic fibrosis.
    Inclusion criteria: This review will consider studies of persons in all age groups with preexisting cystic fibrosis who are diagnosed with COVID-19 using either a polymerase chain reaction, serology, or point-of-care test for SARS-CoV-2. Eligible studies will report the incidence, prevalence, clinical features, or outcomes of COVID-19 in individuals with cystic fibrosis. Studies in community or health care settings from any geographic location will be considered.
    Methods: The JBI methodology for systematic reviews of prevalence and incidence will be used for this review. A methodical search for eligible studies in English (as well as available translations) in MEDLINE, Embase, Scopus, and CINAHL, and unpublished literature in Google Scholar, Dissertation Abstracts International, ProQuest Dissertations and Theses, and MedNar will be conducted from the year 2020 onwards. Studies meeting the inclusion criteria will be selected for appraisal and their methodological quality will be assessed by two independent reviewers based on study titles and abstracts, followed by full-text review focusing on sampling and statistical analysis. Data extraction will be accomplished using a standardized tool. If adequate synthesized data are obtained, a meta-analysis will be conducted; otherwise, the findings will be presented in narrative format, including tables and figures to aid in data presentation.
    Systematic review registration number: PROSPERO CRD42021237792.
    MeSH term(s) Humans ; COVID-19/epidemiology ; Cystic Fibrosis/complications ; Cystic Fibrosis/epidemiology ; Incidence ; Prevalence ; SARS-CoV-2 ; Systematic Reviews as Topic
    Language English
    Publishing date 2022-11-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2689-8381
    ISSN (online) 2689-8381
    DOI 10.11124/JBIES-22-00018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A fatal combination of disseminated strongyloidiasis with two bacterial infections in an immunocompromised host.

    Vini, Vineeta / Antony, Sherly / Jacob, Teena / Sasimohan, Archana / Jacob, Aneeta Mary / Idikula, Mercy John / Cherian, Jacob

    Access microbiology

    2021  Volume 3, Issue 7, Page(s) 246

    Abstract: Introduction: Strongyloides stercoralis: Case report: We report a case of chronic diarrhoea and decreased appetite in a 53-year-old man. He was a chronic alcoholic with diabetes, hypertension and dyslipidaemia and had earlier been treated for ... ...

    Abstract Introduction: Strongyloides stercoralis
    Case report: We report a case of chronic diarrhoea and decreased appetite in a 53-year-old man. He was a chronic alcoholic with diabetes, hypertension and dyslipidaemia and had earlier been treated for pulmonary tuberculosis. He was treated symptomatically for loose stools at a primary health care facility without relief. Following referral to our tertiary care centre, microscopic examination of the stool showed numerous larvae and a few eggs of
    Conclusion: Strongyloidiasis can be diagnosed easily using a very simple but often neglected investigation, namely stool microscopy. This provides an early diagnosis, based on which prompt treatment with the appropriate antihelminthics can be started, thereby reducing the probability of disseminated infection. Disseminated strongyloidiasis is a medical emergency with a poor prognosis, especially in an immunocompromised state. Such patients should be treated aggressively with antihelminthics. They must be monitored for sufficient duration in the hospital for early signs of complication. Their discharge from hospital should be planned based on a negative stool microscopy report in addition to clinical improvement, so as to decrease the mortality reported for both untreated and treated individuals.
    Language English
    Publishing date 2021-07-22
    Publishing country England
    Document type Case Reports
    ISSN 2516-8290
    ISSN (online) 2516-8290
    DOI 10.1099/acmi.0.000246
    Database MEDical Literature Analysis and Retrieval System OnLINE

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