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  1. Article: Intracranial hypertension: classification and patterns of evolution.

    Iencean, St M / Ciurea, A V

    Journal of medicine and life

    2010  Volume 1, Issue 2, Page(s) 101–107

    Abstract: Intracranial hypertension (ICH) was systematized in four categories according to its aetiology and pathogenic mechanisms: parenchymatous ICH with an intrinsic cerebral cause; vascular ICH, which has its actiology in disorders of cerebral blood ... ...

    Abstract Intracranial hypertension (ICH) was systematized in four categories according to its aetiology and pathogenic mechanisms: parenchymatous ICH with an intrinsic cerebral cause; vascular ICH, which has its actiology in disorders of cerebral blood circulation: ICH caused by disorders of cerebro-spinal fluid dynamics and idiopathic ICH. The increase of intracranial pressure is the first to happen and then intracranial hypertension develops from this initial effect becoming symptomatic: it then acquires its individuality, surpassing the initial disease. The intracranial hypertension syndrome corresponds to the stage at which the increased intracranial pressure can be compensated and the acute form of intracranial hypertension is equivalent to a decompensated ICH syndrome. The decompensation of intracranial hypertension is a condition of instability and appears when the normal intrinsic ratio of intracranial pressure time fluctuation is changed. The essential conditions for decompensation of intracranial hypertension are: the speed of intracranial pressure increase over normal values, the highest value of abnormal intracranial pressure and the duration of high ICP values. Medical objectives are preventing ICP from exceeding 20 mm Hg and maintaining a normal cerebral blood flow. The emergency therapy is the same for the acute form but each of the four forms of ICH has a specific therapy, according to the pathogenic mechanism and if possible to aetiology.
    MeSH term(s) Disease Progression ; Humans ; Intracranial Hypertension/classification ; Intracranial Hypertension/diagnosis ; Intracranial Hypertension/physiopathology ; Magnetic Resonance Imaging ; Tomography, X-Ray Computed
    Language English
    Publishing date 2010-01-19
    Publishing country Romania
    Document type Journal Article ; Review
    ZDB-ID 2559353-5
    ISSN 1844-3117 ; 1844-3109 ; 1844-122X
    ISSN (online) 1844-3117 ; 1844-3109
    ISSN 1844-122X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Angiogenesis in the degeneration of the lumbar intervertebral disc.

    David, Gh / Ciurea, A V / Iencean, St M / Mohan, A

    Journal of medicine and life

    2010  Volume 3, Issue 2, Page(s) 154–161

    Abstract: The goal of the study is to show the histological and biochemical changes that indicate the angiogenesis of the intervertebral disc in lumbar intervertebral disc hernia and the existence of epidemiological correlations between these changes and the risk ... ...

    Abstract The goal of the study is to show the histological and biochemical changes that indicate the angiogenesis of the intervertebral disc in lumbar intervertebral disc hernia and the existence of epidemiological correlations between these changes and the risk factors of lumbar intervertebral disc hernia, as well as the patient's quality of life (QOL). We have studied 50 patients aged between 18 and 73 years old, who have undergone lumbar intervertebral disc hernia surgery, making fibroblast growth factor and vascular endothelial growth factor level measurements, as elements in the process of appreciating the disc angiogenesis. Also, pre-surgery and post-surgery QOL has been measured, as well as the intensity of the pain syndrome. We have identified factors capable of stimulating vascular endothelial growth (VEGF, FGF-2) for the examined disc material, but histological examination did not show angiogenesis. The process of angiogenesis at the degenerated intervertebral disc level affects the patient's quality of life both pre and postoperatively, and may be a predictive factor for the post-operative results. Patients can prevent the appearance of angiogenesis type degenerative processes of the intervertebral disc by avoiding angiogenesis correlated factors (weight control, physical effort, and smoking).
    MeSH term(s) Adolescent ; Adult ; Aged ; Cohort Studies ; Female ; Fibroblast Growth Factor 2/metabolism ; Humans ; Intervertebral Disc Degeneration/pathology ; Intervertebral Disc Degeneration/physiopathology ; Intervertebral Disc Degeneration/surgery ; Longitudinal Studies ; Low Back Pain/physiopathology ; Lumbar Vertebrae ; Male ; Middle Aged ; Neovascularization, Pathologic ; Quality of Life ; Vascular Endothelial Growth Factor A/metabolism ; Young Adult
    Chemical Substances VEGFA protein, human ; Vascular Endothelial Growth Factor A ; Fibroblast Growth Factor 2 (103107-01-3)
    Language English
    Publishing date 2010-10-22
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 2559353-5
    ISSN 1844-3117 ; 1844-3109 ; 1844-122X
    ISSN (online) 1844-3117 ; 1844-3109
    ISSN 1844-122X
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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