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  1. Article: Sturge-Weber syndrome with massive macroglossia and anterior neck space infection- a case report and review of literature.

    Iftikhar, Namirah / Khalid, Osama / Ghori, Uzma

    JPMA. The Journal of the Pakistan Medical Association

    2024  Volume 74, Issue 2, Page(s) 394–397

    Abstract: Sturge- Weber syndrome (SWS), is a rare neuro-cutaneous angiomatosis which affects male and females alike. The clinical manifestations include angiomas, haemangiomas of the lips, tongue and palatine region. The oral manifestations are usually unilateral ... ...

    Abstract Sturge- Weber syndrome (SWS), is a rare neuro-cutaneous angiomatosis which affects male and females alike. The clinical manifestations include angiomas, haemangiomas of the lips, tongue and palatine region. The oral manifestations are usually unilateral and are susceptible to bleed. Patients can also present with macroglossia and maxillary bone hypertrophy which can lead to malocclusion of the oral cavity. Food accumulation due to occlusion can cause growth of bacteria which can intensify infections and can cause gingival hyperplasia. A case of a middle-aged 39 year old female was reported in the Ziauddin Hospital, Karachi on 2nd of February,2022 with the presenting complaints of intermittent fever and drowsiness for 10 days. On examination she had massive tongue enlargement, drooling, malocclusion, difficulty in eating and breathing. She was a known case of Sturgeweber syndrome. Based on the clinical and radiological findings, she was managed along the lines of prelaryngeal soft tissue and submandibular infection.
    MeSH term(s) Female ; Humans ; Male ; Middle Aged ; Adult ; Sturge-Weber Syndrome/complications ; Sturge-Weber Syndrome/diagnosis ; Macroglossia/etiology ; Macroglossia/congenital ; Hemangioma ; Hypertrophy ; Malocclusion
    Language English
    Publishing date 2024-02-28
    Publishing country Pakistan
    Document type Review ; Case Reports
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.47391/JPMA.9033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Ogilvie Syndrome Secondary Due To Underlying Hypokalaemia And Anticholinergics: Case Report And Brief Review Of The Literature.

    Iftikhar, Namirah / Rehman Khalid, Muhammad Osama / Ghori, Uzma

    JPMA. The Journal of the Pakistan Medical Association

    2023  Volume 73, Issue 11, Page(s) 2277–2279

    Abstract: Ogilvie's syndrome is a rare but potentially life-threatening condition characterised by massive dilation of the colon without a mechanical obstruction. It typically affects older adults and those with underlying medical conditions, such as neurological ... ...

    Abstract Ogilvie's syndrome is a rare but potentially life-threatening condition characterised by massive dilation of the colon without a mechanical obstruction. It typically affects older adults and those with underlying medical conditions, such as neurological or cardiovascular diseases, and may result in severe complications such as perforation or sepsis. Diagnosis is based on clinical presentation and radiological studies, and treatment involves a combination of conservative measures, such as bowel rest and pharmacological agents, and interventional procedures, such as endoscopic decompression or surgery. Here we present the case of a 67 year old male who presented with Ogilvie's syndrome after changes in his antipsychotic medications. He was given laxatives which led to persistent hypokalemia contributing to worsening distention. This case report highlights the important aspects in management such as cautious use of secretory laxatives (causing worsening Hypokalemia) and combination of motility agents in pseudo colonic obstruction.
    MeSH term(s) Male ; Humans ; Aged ; Colonic Pseudo-Obstruction/diagnostic imaging ; Colonic Pseudo-Obstruction/etiology ; Hypokalemia/chemically induced ; Cholinergic Antagonists ; Decompression, Surgical ; Laxatives ; Lumbar Vertebrae/surgery
    Chemical Substances Cholinergic Antagonists ; Laxatives
    Language English
    Publishing date 2023-11-27
    Publishing country Pakistan
    Document type Review ; Case Reports
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.47391/JPMA.8661
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 845: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Primary Hodgkin's Lymphoma of bone in 7-year-old- an exceptional case report of youngest child in literature.

    Siddiqui, Durr-E-Amna / Akbar, Hira Feroz / Sadiq, Hassan / Iftikhar, Namirah / Khan, Muhammad Rahil / Raza, Muhammad Rafie

    Cancer treatment and research communications

    2021  Volume 29, Page(s) 100448

    Abstract: Hodgkin lymphoma (HL) is mainly considered a nodal disease but extra nodal involvement can also be seen with variable frequency. Solitary bone involvement in HL known as Primary osseous hodgkin lymphoma (POHL) is very rare. It is defined as a lymphoma ... ...

    Abstract Hodgkin lymphoma (HL) is mainly considered a nodal disease but extra nodal involvement can also be seen with variable frequency. Solitary bone involvement in HL known as Primary osseous hodgkin lymphoma (POHL) is very rare. It is defined as a lymphoma that is restricted to the bone without any simultaneous organ or lymph node involvement at the time of initial diagnosis. Primary Hodgkin lymphoma of the bone can be very challenging to diagnose because of its rarity especially in children and its variable presentation. Here we report the youngest case of POHL in a girl 7 years of age. She presented with the left leg pain and B-symptoms of fever and weight loss. Initial workup and imaging were suggestive of infection or a bone tumor. Bone biopsy of left hip joint after the multiple courses of antibiotics revealed Reed Sternberg cells in the mixed inflammatory background with CD30 and PAX-5 immunohistochemical positivity confirming classical hodgkin lymphoma, mixed cellularity type. CD99 and CD1a were negative excluding ewing sarcoma and langerhan cell Histiocytosis respectively. Absence of significant lymphadenopathy or visceromegaly on staging computerized tomography (CT) scan confirmed a very rare POHL. She received standard conventional chemotherapy with radiation. Our patient is in remission for five years after treatment.
    MeSH term(s) Bone Neoplasms/diagnosis ; Bone Neoplasms/pathology ; Child ; Female ; Hodgkin Disease/diagnosis ; Hodgkin Disease/pathology ; Humans
    Language English
    Publishing date 2021-08-19
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 2468-2942
    ISSN (online) 2468-2942
    DOI 10.1016/j.ctarc.2021.100448
    Database MEDical Literature Analysis and Retrieval System OnLINE

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