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Article ; Online: Evaluating the impact of a darts game intervention on cognitive function in older adults with and without mild cognitive impairment: a pilot study.

Kawabata, Nami / Iida, Tadayuki / Kunishige, Masafumi / Fukuda, Hiroshi / Miyaguchi, Hideki / Harada, Toshihide

Frontiers in rehabilitation sciences

2024 Volume 5, Page(s) 1327494

Abstract: Introduction: The current study investigated the relationship between the characteristics of a darts game, including the throwing motion toward a target, and mild cognitive impairment (MCI). To this end, we examined the associations between cognitive ... ...

Abstract	Introduction: The current study investigated the relationship between the characteristics of a darts game, including the throwing motion toward a target, and mild cognitive impairment (MCI). To this end, we examined the associations between cognitive function and mental health, and the shift in center of gravity while throwing darts. In a preliminary investigation, a 1-month dart game intervention was conducted among older individuals living in the community. The participants were divided into the non-MCI and MCI groups, and the relationship between center of gravity movement during throwing and the presence of dementia was examined. Methods: The intervention lasted for 1 month and was tested on healthy older individuals (aged ≥ 65 years) recruited from the community. The Japanese version of the Montreal Cognitive Assessment and the Trail Making Test was used to assess cognitive function. Mental health was evaluated using the Kessler Psychological Distress Scale and the Subjective Well-being Inventory. The center of pressure was analyzed to determine the center of gravity shift during dart throwing. Results: The analysis of factors influencing the determination of the MCI score during the intervention revealed a tendency for the center of gravity shift to be associated as a protective factor in the non-MCI group, although this association did not reach statistical significance (odds ratio = 0.942, Conclusion: The current findings suggest that conducting center of gravity shift testing could potentially provide a helpful tool for predicting early decline in cognitive function.
Language	English
Publishing date	2024-02-05
Publishing country	Switzerland
Document type	Journal Article
ISSN	2673-6861
ISSN (online)	2673-6861
DOI	10.3389/fresc.2024.1327494
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Article: Persistence of Low Back Pain and Predictive Ability of Pain Intensity and Disability in Daily Life among Nursery School Workers in Japan: A Five-Year Panel Study.

Aoshima, Megumi / Shi, Xuliang / Iida, Tadayuki / Hiruta, Shuichi / Ono, Yuichiro / Ota, Atsuhiko

Healthcare (Basel, Switzerland)

2024 Volume 12, Issue 2

Abstract: Nursery school workers are known for having a high prevalence of low back pain (LBP). The natural history of LBP and the determinants of persistent LBP remain unclear. We examined the prevalence of persistent LBP and whether pain intensity and disability ...

Abstract	Nursery school workers are known for having a high prevalence of low back pain (LBP). The natural history of LBP and the determinants of persistent LBP remain unclear. We examined the prevalence of persistent LBP and whether pain intensity and disability in daily life due to LBP affected the persistence of LBP among these workers. A five-year panel study was conducted for 446 nursery school workers in Japan. LBP, pain intensity, and disability in daily life due to LBP were assessed with a self-administered questionnaire survey. Pain intensity was assessed using the numerical rating scale (NRS). The Roland-Morris Disability Questionnaire (RDQ) was used to assess disability in daily life due to LBP. At baseline, 270 nursery school workers (60.5%) suffered from LBP. The estimated prevalence of persistent LBP was 84.6% (80.3-88.9%), 82.2% (77.7-86.8%), and 82.0% (77.4-86.5%) at 1, 3, and 5 years after the initial study, respectively. NRS scores of 5 or greater predicted the persistence of LBP at 1 and 3 years after the initial survey (adjusted odds ratios: 4.01 (1.27-12.6) and 8.51 (1.87-38.7), respectively), while RDQ scores did not. In conclusion, LBP highly persisted for a long time and pain intensity predicted persistent LBP among nursery school workers in Japan.
Language	English
Publishing date	2024-01-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2721009-1
ISSN	2227-9032
ISSN	2227-9032
DOI	10.3390/healthcare12020128
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Article: Association of Mammary Gland Disease With Metabolic Syndrome Factors in Japanese Women-Case-Control Study Based on Health Screening Results.

Sumida, Sakika / Iida, Tadayuki / Yoshikawa, Masao / Nagaoka, Kaoru

Breast cancer : basic and clinical research

2022 Volume 16, Page(s) 11782234221127652

Abstract: Background: The association of obesity with breast cancer is clear. Although body mass index (BMI) is used as an indicator of obesity, its accuracy remains questionable. Although, there factors for diagnosing metabolic syndrome are caused by obesity, ... ...

Abstract	Background: The association of obesity with breast cancer is clear. Although body mass index (BMI) is used as an indicator of obesity, its accuracy remains questionable. Although, there factors for diagnosing metabolic syndrome are caused by obesity, the association with breast cancer has not been clarified. Methods: Women who underwent breast cancer screening with mammography and measurements of metabolic syndrome factors, including waist circumference, blood glucose, triglycerides, HDL (high-density lipoprotein) cholesterol levels, and systolic and diastolic pressure, twice within a 2-year period were enrolled (n = 314), with a final sample size of 256. To determine the presence of mammary gland disease, 2 expert physicians interpreted radiogram findings, with category 3 or higher shown by mammography considered to indicate an abnormality. Results and conclusions: Waist circumference at the initial measurement was marginally significant as a risk factor for onset of mammary gland disease (odds ratio [OR] = 1.036,
Language	English
Publishing date	2022-11-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	2423804-1
ISSN	1178-2234
ISSN	1178-2234
DOI	10.1177/11782234221127652
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Article ; Online: Psychosocial work characteristics and low back pain in daycare (nursery) workers in Japan: a prospective cohort study.

Shi, Xuliang / Aoshima, Megumi / Iida, Tadayuki / Hiruta, Shuichi / Ono, Yuichiro / Ota, Atsuhiko

BMC musculoskeletal disorders

2022 Volume 23, Issue 1, Page(s) 1055

Abstract: Background: Low back pain (LBP) is one of the most common musculoskeletal problems affecting daycare (nursery) workers. We aimed to identify the psychosocial factors influencing LBP in daycare workers.: Methods: We conducted a prospective cohort ... ...

Abstract	Background: Low back pain (LBP) is one of the most common musculoskeletal problems affecting daycare (nursery) workers. We aimed to identify the psychosocial factors influencing LBP in daycare workers. Methods: We conducted a prospective cohort study with a one-year observation period. The baseline sample was a convenience sample of 444 daycare workers from 34 daycare facilities in Nagoya, Japan, and its suburbs. All the data were collected through a questionnaire survey. The question "Where are you currently feeling LBP?" was used to determine whether the subjects suffered from LBP. We examined the prospective relationships of the psychosocial work characteristics, i.e., high job strain, low social support, effort-reward imbalance, and overcommitment, at baseline and LBP after one year. We used multiple logistic regression analyses to calculate the odds ratios of psychosocial work characteristics for the persistence and onset of LBP, adjusted for age, sex, body mass index, smoking, employment status, occupation, and working schedule. Results: At baseline, 270 (60.8%) subjects suffered from LBP. Of 208 who also gave information on LBP one year later, 176 (84.6%) suffered from the persistence of LBP. Low social support at baseline was significantly related to persistent LBP one year later. The incidence of persistent LBP was 89.9% and 80.0% among those with and without low social support at baseline, respectively. The adjusted odds ratio (95% confidence interval) of low social support at baseline for the persistence of LBP was 2.43 (1.01-5.87). Of 150 who were without LBP at baseline and provided information on LBP one year later, 45 (30.0%) suffered from the onset of LBP. None of the psychosocial work characteristics showed significant relationships with the onset of LBP one year later. Conclusion: Low social support was related to the persistence, but not to the onset of LBP in a prospective cohort analysis among daycare workers in Japan. High job strain, ERI, or overcommitment did not show a significant prospective effect on LBP.
MeSH term(s)	Humans ; Low Back Pain/diagnosis ; Low Back Pain/epidemiology ; Prospective Studies ; Japan/epidemiology ; Employment ; Social Support
Language	English
Publishing date	2022-12-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2041355-5
ISSN	1471-2474 ; 1471-2474
ISSN (online)	1471-2474
ISSN	1471-2474
DOI	10.1186/s12891-022-06009-x
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Article ; Online: Brazilian Propolis Intake Decreases Body Fat Mass and Oxidative Stress in Community-Dwelling Elderly Females: A Randomized Placebo-Controlled Trial.

Kanazashi, Miho / Iida, Tadayuki / Nakanishi, Ryosuke / Tanaka, Masayuki / Ikeda, Hiromi / Takamiya, Naomi / Maeshige, Noriaki / Kondo, Hiroyo / Nishigami, Tomohiko / Harada, Toshihide / Fujino, Hidemi

Nutrients

2023 Volume 15, Issue 2

Abstract: This study aimed to investigate the effects of Brazilian propolis on body fat mass and levels of adiponectin and reactive oxygen species among community-dwelling elderly females. This was a double-blind randomized placebo-controlled trial. Altogether, 78 ...

Abstract	This study aimed to investigate the effects of Brazilian propolis on body fat mass and levels of adiponectin and reactive oxygen species among community-dwelling elderly females. This was a double-blind randomized placebo-controlled trial. Altogether, 78 females aged 66-84 years were randomly assigned to the propolis (PRO;
MeSH term(s)	Aged ; Female ; Humans ; Adiponectin ; Adipose Tissue ; Brazil ; Dietary Supplements ; Independent Living ; Oxidative Stress ; Polyesters ; Propolis/pharmacology ; Propolis/therapeutic use ; Aged, 80 and over
Chemical Substances	Adiponectin ; Polyesters ; Propolis (9009-62-5)
Language	English
Publishing date	2023-01-11
Publishing country	Switzerland
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15020364
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Article ; Online: Spatial navigation ability is associated with the assessment of smoothness of driving during changing lanes in older drivers.

Kunishige, Masafumi / Miyaguchi, Hideki / Fukuda, Hiroshi / Iida, Tadayuki / Nami, Kawabata / Ishizuki, Chinami

Journal of physiological anthropology

2020 Volume 39, Issue 1, Page(s) 25

Abstract: Background: Age-related changes affect driving ability, including the smoothness of driving. This operation requires the use of both allocentric strategies (based on world-centered representations) and egocentric strategies (based on self-centered ... ...

Abstract	Background: Age-related changes affect driving ability, including the smoothness of driving. This operation requires the use of both allocentric strategies (based on world-centered representations) and egocentric strategies (based on self-centered representations); however, with age, a greater preference for egocentric strategies is evident when driving. Furthermore, an age-related decline occurs in both driving ability and spatial navigation. We therefore assessed the relationship between spatial navigation and driving smoothness and tested whether a driving simulator can be used to evaluate smooth lane changes in older drivers. Methods: A total of 34 healthy older drivers (mean age: 68.2 ± 5.4 years old) and 20 younger drivers (mean age = 20.2 ± 5.4 years old) participated in this study. The smoothness of driving was assessed using a driving simulator and spatial navigation was assessed using the Card-Placing Test-A/B. We also assessed visual perception and general intellectual function using standard neuropsychological tests. Results: Older drivers had significantly worse spatial navigation and exhibited less smooth driving than younger drivers. Furthermore, we found a negative correlation between the smoothness of driving and spatial navigation within both groups. These results suggest that the deterioration in spatial navigation in older people may underlie the observed decrease in driving smoothness, and that spatial navigation and smooth driving deteriorate with age. Conclusions: Considering these results, we found a significant correlation in the older group between the smoothness of vehicle movement and spatial navigation, in the smoothness of vehicle movement between the young and old groups. The smoothness values, which indices thoroughly derived from the driving simulator are indeed showing some evidence in ego/allocentric cognitions, which may change by age. The driving simulator could aid the development of intervention programs or assessment measures for drivers with a decreased function.
MeSH term(s)	Adult ; Aged ; Automobile Driving/psychology ; Automobile Driving/statistics & numerical data ; Computer Simulation ; Female ; Humans ; Male ; Middle Aged ; Spatial Navigation/physiology ; Task Performance and Analysis ; Young Adult
Language	English
Publishing date	2020-08-27
Publishing country	England
Document type	Journal Article
ZDB-ID	2248072-9
ISSN	1880-6805 ; 1880-6791 ; 1345-3475
ISSN (online)	1880-6805
ISSN	1880-6791 ; 1345-3475
DOI	10.1186/s40101-020-00227-9
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Article: Effects of Psychological and Physical Stress on Oxidative Stress, Serotonin, and Fatigue in Young Females Induced by Objective Structured Clinical Examination: Pilot Study of u-8-OHdG, u-5HT, and s-HHV-6.

Iida, Tadayuki / Ito, Yasuhiro / Kanazashi, Miho / Murayama, Susumu / Miyake, Takashi / Yoshimaru, Yuki / Tatsumi, Asami / Ezoe, Satoko

International journal of tryptophan research : IJTR

2021 Volume 14, Page(s) 11786469211048443

Abstract: Background: To establish a method to prevent and manage fatigue caused by psychological and physical stress in young females, early detection factors, such as understanding of fatigue and causes of psychological and physical stress, as well as a review ... ...

Abstract	Background: To establish a method to prevent and manage fatigue caused by psychological and physical stress in young females, early detection factors, such as understanding of fatigue and causes of psychological and physical stress, as well as a review of early management of psychiatric disease, are important. With increasing knowledge regarding the diverse causes of stress, it is important to select biomarkers with consideration of the types of stress burden and mechanisms underlying the development of physical symptoms. The methods used to search for stress characteristics is an issue that needs to be addressed. However, consensus regarding objective assessment methods for impaired mental health is lacking. Methods: We examined the effects of an objective structured clinical examination (OSCE), considered to be a uniform source of psychological and physical stress, on biomarkers of oxidative stress and fatigue in 16 third-year female medical university students (21.3 ± 2.1 years old) in Japan with a normal menstrual cycle. A self-administered questionnaire consisting of Zung's Self-rating Depression Scale (SDS) and State-Trait Anxiety Inventory (STAI) was used to assess subjective stress. Furthermore, stress-related biomarkers (urinary 8-hydroxy-2'-deoxyguanosine [u-8-OHdG], urinary 5-hydroxytryptamine [u-5-HT], and salivary human herpesvirus-6 [s-HHV-6]) were examined at 1 month, 1 week, and 1 day before, and 1 week after the OSCE. Results: The results indicated that the OSCE did not have effects on u-8-OHdG, a biomarker of oxidative stress. However, u-5-HT and s-HHV-6 were found to be elevated in examinations performed prior to the OSCE. Conclusions: The present findings suggest that u-5-HT and s-HHV-6 levels can be used for objective assessment of mental and physical fatigue in young females, including that produced not only by knowledge regarding an upcoming OSCE, but also by skill and attitude aspects related to that examination.
Language	English
Publishing date	2021-10-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2517435-6
ISSN	1178-6469
ISSN	1178-6469
DOI	10.1177/11786469211048443
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Article: Effects of Lemon Beverage Containing Citric Acid with Calcium Supplementation on Bone Metabolism and Mineral Density in Postmenopausal Women: Double-Blind 11-Month Intervention Study.

Ikeda, Hiromi / Iida, Tadayuki / Hiramitsu, Masanori / Inoue, Takashi / Aoi, Satomi / Kanazashi, Miho / Ishizaki, Fumiko / Harada, Toshihide

Journal of nutrition and metabolism

2021 Volume 2021, Page(s) 8824753

Abstract: A critical factor for preventing osteoporosis after menopause is attenuation of the accelerated turnover rate of bone metabolism. The present randomized controlled study was conducted to clarify the effects of a lemon beverage with calcium (Ca) ... ...

Abstract	A critical factor for preventing osteoporosis after menopause is attenuation of the accelerated turnover rate of bone metabolism. The present randomized controlled study was conducted to clarify the effects of a lemon beverage with calcium (Ca) supplementation that makes use of the chelating action of citric acid. Comprehensive evaluations of bone were performed by assessments of bone mineral density (BMD) and biomarkers related to bone turnover. Seventy-nine postmenopausal women were enrolled and asked to participate in an 11-month continuous intake of the test beverages. The subjects were divided into three groups: those who consumed a lemon beverage containing citric acid with Ca supplementation (LECA group), those who consumed a lemon beverage containing citric acid without Ca supplementation (LE group), and those who consumed no test beverage (control group). Using a double-blind protocol, subjects in the LECA and LE groups consumed one bottle containing 290 mL of the test beverage each day. The ratio of change in BMD after 11 months was significantly higher in the LECA group as compared to the control and LE groups. The LECA group also showed significant decreases in concentrations of tartrate-resistant acid phosphatase 5b (TRACP-5b), a bone resorption marker, and bone alkaline phosphatase (BAP) as compared to the other groups, as well as a significant decrease in concentration of osteocalcin (OC), a bone formation marker, as compared to the LE group. Based on our findings, we speculated that bone resorption and bone formation in postmenopausal women might be suppressed along with an increase in Ca resorption caused by chelation of citric acid in association with continuous ingestion of a Ca-supplemented lemon beverage containing citric acid, resulting in suppression of high bone metabolic turnover. In addition, the results provide information regarding BMD maintenance in the bones of the trunk, including the lumbar spine and proximal femur.
Language	English
Publishing date	2021-02-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	2573563-9
ISSN	2090-0732 ; 2090-0724
ISSN (online)	2090-0732
ISSN	2090-0724
DOI	10.1155/2021/8824753
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Article ; Online: Spatial navigation ability and gaze switching in older drivers: A driving simulator study.

Kunishige, Masafumi / Fukuda, Hiroshi / Iida, Tadayuki / Kawabata, Nami / Ishizuki, Chinami / MIyaguchi, Hideki

Hong Kong journal of occupational therapy : HKJOT

2019 Volume 32, Issue 1, Page(s) 22–31

Abstract: Objective: Driving ability in older people is affected by declining motor, cognitive and visual functions. We compared perceptual and cognitive skills and driving behaviour in a Japanese population.: Methods: We used a driving simulator to measure ... ...

Abstract	Objective: Driving ability in older people is affected by declining motor, cognitive and visual functions. We compared perceptual and cognitive skills and driving behaviour in a Japanese population. Methods: We used a driving simulator to measure the effects of spatial navigation skills and eye movements on driving ability. Participants were 34 older and 20 young adults who completed a simulated driving task involving a lane change and a right turn at an intersection. We used an eye tracker to measure gaze. We measured visual recognition (Benton Judgment of Line Orientation Test (BJLO)), spatial navigation (Card-Placing Test (CPT A & B)), visual perception (Raven's Colored Progressive Matrices (RCPM)) and driving ability (Stroke Drivers' Screening Assessment). Results: Older participants scored significantly lower on the BJLO, CPT-A & B and RCPM, showed a significant correlation between gaze time and CPT-A & B scores (both p < .01) and had a longer gaze time. There were significant between-group differences in saccade switching (p < .01 right turn), distance per saccade (p < .05 for right turn and lane change) and saccade total distance (p < .05 right turn; p < .01 lane change). There was an association between age and rate of gaze at the right door mirror (p = 0.04). Conclusion: The findings indicate that older drivers have poorer eye movement control and spatial navigation. This is likely to result in delayed responses and difficulties in predicting the on-coming driving environment. Driving simulation could help older drivers in their driving abilities.
Language	English
Publishing date	2019-02-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2202253-3
ISSN	1876-4398 ; 1569-1861
ISSN (online)	1876-4398
ISSN	1569-1861
DOI	10.1177/1569186118823872
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Article ; Online: Knowledge, attitudes, and practices of Japanese travelers on infectious disease risks and immunization uptake.

Namikawa, Kyoko / Iida, Tadayuki / Ouchi, Kazunobu / Kimura, Mikio

Journal of travel medicine

2010 Volume 17, Issue 3, Page(s) 171–175

Abstract: Background: There is concern that Japanese travelers are poorly protected against travel-associated infectious diseases including vaccine-preventable infections. This prompted us to study Japanese travelers for measures taken to reduce their risk of ... ...

Abstract	Background: There is concern that Japanese travelers are poorly protected against travel-associated infectious diseases including vaccine-preventable infections. This prompted us to study Japanese travelers for measures taken to reduce their risk of acquiring an infectious disease and their immunization uptake. Methods: During April 2007 to May 2008, a questionnaire study was conducted using the European Travel Health Advisory Board (ETHAB) protocol and targeting Japanese group tour clients as well as individual travelers to developing countries. Results: A total of 302 returned questionnaires were analyzed. While the majority (87.4%) sought general information on their destination, few (38.7%) sought the travel health information. Very few (2.0%) got the health information from travel medicine specialists. More than half were either unaware of the risks or thought there was no risk of hepatitis A, hepatitis B, and typhoid fever in their destination. Only half (50.7%) thought vaccines provided sufficient protection and very few (13.6%) believed that vaccines were safe. For most of the vaccine-preventable diseases, only fewer than 10% had received the vaccines. Conclusions: There is a need for specialized travel health services in Japan and health professionals should be encouraged to expand these services. Japanese travelers should be made aware of the importance of seeking pre-travel health advice and information on the health risks at their destination. Travel health professionals should provide a balanced view of the risks and benefits of immunization, and misperceptions about immunization should be addressed.
MeSH term(s)	Adult ; Asian Continental Ancestry Group ; Communicable Disease Control ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Immunization/statistics & numerical data ; Immunization/utilization ; Japan ; Male ; Middle Aged ; Patient Acceptance of Health Care/ethnology ; Patient Acceptance of Health Care/statistics & numerical data ; Risk ; Surveys and Questionnaires ; Travel ; Young Adult
Language	English
Publishing date	2010-05
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1212504-0
ISSN	1708-8305 ; 1195-1982
ISSN (online)	1708-8305
ISSN	1195-1982
DOI	10.1111/j.1708-8305.2010.00405.x
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