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  1. Article ; Online: Successful low-dose corticosteroid treatment of aggressive pyoderma gangrenosum with irritable bowel syndrome: a case report.

    Ilyas, Faridha

    Acta dermatovenerologica Alpina, Pannonica, et Adriatica

    2022  Volume 31, Issue 3, Page(s) 111–114

    Abstract: Pyoderma gangrenosum (PG) is a rare and chronic cutaneous disorder characterized by painful ulcers that progresses rapidly. The disease is thought to be immune-mediated. However, the exact etiopathogenesis of the disease has yet to be clearly established. ...

    Abstract Pyoderma gangrenosum (PG) is a rare and chronic cutaneous disorder characterized by painful ulcers that progresses rapidly. The disease is thought to be immune-mediated. However, the exact etiopathogenesis of the disease has yet to be clearly established. The disease is often misdiagnosed as other cutaneous disorders, most notably infections such as cellulitis in its initial stage. Failure of antibiotic treatment is one of the signs when a diagnosis of PG should be considered. Due to its rampant lesion evolution, aggressive corticosteroid therapy has long been used as the mainstay treatment for PG. However, this can lead to side effects such as gastrointestinal bleeding, especially in patients with autoimmune diseases such as inflammatory bowel disease (IBD). We report the case of a 54-year-old female patient with PG that was initially misdiagnosed as cellulitis and furunculosis along with IBD. She was treated using a low-dose regimen of methylprednisolone, which resulted in significant clinical improvement and complete resolution after 2 months of therapy.
    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Cellulitis/complications ; Female ; Humans ; Inflammatory Bowel Diseases/complications ; Irritable Bowel Syndrome/complications ; Methylprednisolone/therapeutic use ; Middle Aged ; Pyoderma Gangrenosum/complications ; Pyoderma Gangrenosum/drug therapy
    Chemical Substances Adrenal Cortex Hormones ; Anti-Bacterial Agents ; Methylprednisolone (X4W7ZR7023)
    Language English
    Publishing date 2022-09-23
    Publishing country Slovenia
    Document type Case Reports ; Journal Article
    ZDB-ID 1235900-2
    ISSN 1581-2979 ; 1318-4458 ; 0302-4466
    ISSN (online) 1581-2979
    ISSN 1318-4458 ; 0302-4466
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Effects of

    Sara, Meutia / Ilyas, Faridha / Hasballah, Kartini / Nurjannah, Nurjannah / Mudatsir, Mudatsir

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 11

    Abstract: Background and ... ...

    Abstract Background and Objectives
    MeSH term(s) Child ; Humans ; Animals ; Dermatitis, Atopic/drug therapy ; Staphylococcus aureus ; Oligochaeta ; Staphylococcal Infections ; Interleukins ; Fluocinolone Acetonide/pharmacology ; Fluocinolone Acetonide/therapeutic use ; Severity of Illness Index
    Chemical Substances Interleukins ; Fluocinolone Acetonide (0CD5FD6S2M)
    Language English
    Publishing date 2023-11-15
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59112007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Prevalence of the HLA-Cw6 genotype and zinc deficiency in psoriasis vulgaris patients in Indonesia.

    Sangian, Timothy Yusuf / Waspodo, Nurelly Noro / Ilyas, Faridha / Djawad, Khairuddin / Seweng, Arifin / Tawali, Suryani

    Acta dermatovenerologica Alpina, Pannonica, et Adriatica

    2023  Volume 32, Issue 3, Page(s) 93–97

    Abstract: Introduction: Psoriasis vulgaris is an immune-mediated inflammatory disease influenced by genetic and immunologic factors, including micronutrient deficiencies. The HLA-Cw6 gene and zinc level have been separately studied in psoriasis patients, yielding ...

    Abstract Introduction: Psoriasis vulgaris is an immune-mediated inflammatory disease influenced by genetic and immunologic factors, including micronutrient deficiencies. The HLA-Cw6 gene and zinc level have been separately studied in psoriasis patients, yielding inconsistent findings. A descriptive study regarding HLA-Cw6 allele expression, zinc levels, and their direct correlation in Indonesia is lacking.
    Methods: This prospective case-control study involved 33 psoriasis patients and 33 age- and sex-matched control patients at the dermatology clinic affiliated with Hasanuddin University in South Sulawesi in 2021. Cases were classified into mild, moderate, and severe psoriasis according to Psoriasis Area and Severity Index (PASI) score. An EDTA tube was used to take a 5 ml blood sample, followed by analysis for PCR of the HLA-Cw6 allele and a colorimetric assay to measure zinc level. Statistical analysis was performed to determine the association between HLA-Cw6 and zinc level and psoriasis disease severity.
    Results: Among the 33 psoriatic patients enrolled in this study, three (9.1%) of the cases were classified as mild psoriasis, 10 (30.3%) were classified as moderate psoriasis, and 20 (60.6%) were classified as severe psoriasis. The HLA-Cw6 allele was detected in 93.9% of psoriasis cases and in 3% of control patients (p < 0.001). The HLA-Cw6 allele was detected consecutively in 66.7%, 90.0%, and 100% of mild, moderate, and severe psoriasis patients, respectively. Zinc levels were lower in psoriasis patients compared to controls (16.85 ± 3.55 vs. 13.74 ± 3.78 μmol/l). Severe psoriasis patients exhibited the lowest average zinc level (14.76 ± 1.40 μmol/l, 15.48 ± 4.20 μmol/l, and 12.72 ± 3.56 μmol/l in mild, moderate, and severe patients, respectively). The mean zinc level in HLA-Cw6-positive patients was 13.68 μmol/l, and 14.6 μmol/l in HLA-Cw6-negative patients (p = 0.495).
    Conclusions: The study revealed the presence of HLA-Cw6 allele expression and decreased serum zinc levels in psoriasis patients compared to controls. Both factors demonstrated associations with psoriasis disease severity.
    MeSH term(s) Humans ; Indonesia ; Prevalence ; Case-Control Studies ; Psoriasis/genetics ; Genotype ; Zinc
    Chemical Substances HLA-C*06 antigen ; Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2023-09-25
    Publishing country Slovenia
    Document type Journal Article
    ZDB-ID 1235900-2
    ISSN 1581-2979 ; 1318-4458 ; 0302-4466
    ISSN (online) 1581-2979
    ISSN 1318-4458 ; 0302-4466
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Recalcitrant Cutaneous Lupus Erythematosus during COVID-19 Pandemic: A Case Report.

    Yunus, Muhlis / Dahliana, Andi Putri / Habar, Wiwiek / Ilyas, Faridha / Wijaya, Jonathan Kurnia

    Skinmed

    2023  Volume 21, Issue 2, Page(s) 118–121

    Abstract: A 30-year-old woman visited the dermatology and venereology clinic with red rashes on her cheeks with spreading wounds to the ears present for 6 months. Similar ailments were also found on the chest and upper arms accompanying black spots on both palms. ... ...

    Abstract A 30-year-old woman visited the dermatology and venereology clinic with red rashes on her cheeks with spreading wounds to the ears present for 6 months. Similar ailments were also found on the chest and upper arms accompanying black spots on both palms. Initially, red rashes appeared intermittently, observed around the eyes and cheeks, especially at sun exposure. Tenderness or pruritus was not present; however, the patient had joints ache, sore fingers, hair loss as well as frequent fever.
    MeSH term(s) Female ; Humans ; Adult ; Pandemics ; COVID-19/complications ; Lupus Erythematosus, Cutaneous ; Alopecia/complications ; Lupus Erythematosus, Systemic/complications
    Language English
    Publishing date 2023-05-09
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2171125-2
    ISSN 1751-7125 ; 1540-9740
    ISSN (online) 1751-7125
    ISSN 1540-9740
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Nail Fold Dermatoscopic Findings in Scleroderma Patients.

    Djuardi, Irene / Ilyas, Faridha / Djawad, Khairuddin / Helina, Irma / Wibisono, Olivia

    Skinmed

    2020  Volume 18, Issue 5, Page(s) 308–310

    Abstract: Case 1: A 28-year-old woman with previously excellent health presented with pain, swelling, and stiffness on the face and hands, which had persisted for over 18 months. She had initially experienced intermittent pain in both knees. Skin hardening spread ...

    Abstract Case 1: A 28-year-old woman with previously excellent health presented with pain, swelling, and stiffness on the face and hands, which had persisted for over 18 months. She had initially experienced intermittent pain in both knees. Skin hardening spread to both hands until the fingers could no longer be straightened. There were intermittent pain and skin hardening on the cheeks extending to the neck. These were accompanied by breathing difficulty, especially during high-intensity activity.
    MeSH term(s) Adult ; Dermoscopy/methods ; Face/pathology ; Female ; Hand/pathology ; Humans ; Middle Aged ; Nails/pathology ; Pain/etiology ; Scleroderma, Systemic/diagnosis ; Scleroderma, Systemic/pathology
    Language English
    Publishing date 2020-10-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2171125-2
    ISSN 1751-7125 ; 1540-9740
    ISSN (online) 1751-7125
    ISSN 1540-9740
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Glove-Induced Hand Dermatitis: A Study in Healthcare Workers during COVID-19 Pandemic in Indonesia.

    Prakoeswa, Cita Rosita Sigit / Damayanti / Anggraeni, Sylvia / Umborowati, Menul Ayu / Waskito, Fajar / Indrastuti, Niken / Febriana, Sri Awalia / Sari, Agnes Rosarina Prita / Nababan, Kristo Alberto / Hazlianda, Cut Putri / Nopriyati / Budianti, Windy Keumala / Pangastuti, Miranti / Ilyas, Faridha / Kartini, Agnes / Rusetiyanti, Nurwestu / Anggraini, Ika / Idrus, Idrianti / Brahmanti, Herwinda /
    Akhyar, Gardenia

    Dermatology research and practice

    2023  Volume 2023, Page(s) 6600382

    Abstract: Skin damage among healthcare workers has been reported by many centers around the world. Occupational hand dermatitis is one of the most commonly known occupational skin diseases and a socially significant health issue. The use of gloves is one of the ... ...

    Abstract Skin damage among healthcare workers has been reported by many centers around the world. Occupational hand dermatitis is one of the most commonly known occupational skin diseases and a socially significant health issue. The use of gloves is one of the risk factors for the occurrence and/or aggravation of hand dermatitis. This cross-sectional study involved healthcare workers in 14 referral hospitals for COVID-19 throughout Indonesia. Questionnaires were distributed to the participants, which consisted of the subject's characteristics, glove-related skin problems, history of glove use, and clinical history. This study involved a total of 845 healthcare workers. Approximately 156 healthcare workers (18.46%) had glove-induced hand dermatitis during the pandemic. Itchy skin was the most common symptom (44.23%), and the palm was the most frequently complained area (48.72%). There was a significant association between glove use and glove-induced hand dermatitis among healthcare workers. In particular, equal to or more than 2 hours per day of glove use was significantly associated with hand dermatitis. Glove-induced hand dermatitis also had a significant association with the subject's history of atopic dermatitis and previous history of hand dermatitis. The use of gloves by healthcare workers should be considered carefully, especially in individuals at increased risk, including those who use gloves for 2 hours or more per day and those who have a history of atopic or hand dermatitis, in order to prevent the incidence of glove-induced hand dermatitis among healthcare workers, as well as to provide a safe working environment.
    Language English
    Publishing date 2023-08-02
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2548952-5
    ISSN 1687-6113 ; 1687-6105
    ISSN (online) 1687-6113
    ISSN 1687-6105
    DOI 10.1155/2023/6600382
    Database MEDical Literature Analysis and Retrieval System OnLINE

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