Article ; Online: Breast Cancer after Radiation Therapy in a Patient with Li-Fraumeni Syndrome
대한영상의학회지, Vol 83, Iss 1, Pp 246-
A Case Report
2022 Volume 251
Abstract: Li-Fraumeni syndrome (LFS) is an inherited autosomal-dominant tumor-predisposition disorder caused by germline mutations in the TP53 tumor suppressor gene. Since patients with LFS are likely to develop therapy-related cancers, radiation therapy should be ...
Abstract | Li-Fraumeni syndrome (LFS) is an inherited autosomal-dominant tumor-predisposition disorder caused by germline mutations in the TP53 tumor suppressor gene. Since patients with LFS are likely to develop therapy-related cancers, radiation therapy should be avoided if breast cancer is found in these individuals. Herein, we present a case of secondary breast cancer in an LFS patient after radiation and chemotherapy for the first diagnosed breast sarcoma. |
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Keywords | breast neoplasms ; li-fraumeni syndrome ; sarcoma ; second primary ; Medical physics. Medical radiology. Nuclear medicine ; R895-920 |
Language | English |
Publishing date | 2022-01-01T00:00:00Z |
Publisher | The Korean Society of Radiology |
Document type | Article ; Online |
Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
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