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  1. Article ; Online: Mortality predictors of patients diagnosed with severe hyponatremia in the emergency department.

    Gurbuz, Mesut / Acehan, Selen / Satar, Salim / Gulen, Muge / Sevdımbas, Sarper / Ince, Cagdas / Onan, Engin

    Irish journal of medical science

    2024  

    Abstract: Purpose: To determine the factors affecting mortality as a result of the analysis of the demographic and clinical characteristics and laboratory parameters of patients whose serum Na value was determined to be 125 mEq/L or below at the time of admission ...

    Abstract Purpose: To determine the factors affecting mortality as a result of the analysis of the demographic and clinical characteristics and laboratory parameters of patients whose serum Na value was determined to be 125 mEq/L or below at the time of admission to the emergency department (ED).
    Method: Patients over 18 years of age who admitted to the ED of a tertiary hospital between September 2021 and September 2022 and whose serum sodium level was determined to be 125 mEq/L and below were included in the study. Demographic and clinical characteristics, admission complaints, medications used, Charles comorbidity index (CCI), laboratory parameters, and outcomes of the patients included in the study were recorded in the data form.
    Results: Three hundred ninety-nine patients were included in the study. When the 30-day mortality of the patients is examined, the mortality rate was found to be 21.6%. In the analyses performed for the predictive power of laboratory parameters for mortality, it was determined that the highest predictive power among the predictive values determined by the area under the curve (AUC) was the albumin level (AUC 0.801, 95% CI 0.753-0.849, p < 0.001). In the binary logistic regression analysis, urea and albumin were independent predictors of 30-day mortality.
    Conclusion: According to study data, albumin and urea levels are independent predictors of 30-day mortality in patients diagnosed with severe hyponatremia in the emergency department.
    Language English
    Publishing date 2024-01-31
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 390895-1
    ISSN 1863-4362 ; 0021-1265
    ISSN (online) 1863-4362
    ISSN 0021-1265
    DOI 10.1007/s11845-024-03615-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A fatal case of acetamiprid poisoning with turquoise urine.

    Gulen, Muge / Satar, Salim / Ince, Cagdas

    Journal of forensic and legal medicine

    2022  Volume 87, Page(s) 102335

    Abstract: Acetamiprid is a member of neonicotinoid insecticides with a low risk of toxicity in humans. However, ingestion of large amounts may cause severe poisoning. This is the first case reported in the literature in which severe toxicity and death occurred ... ...

    Abstract Acetamiprid is a member of neonicotinoid insecticides with a low risk of toxicity in humans. However, ingestion of large amounts may cause severe poisoning. This is the first case reported in the literature in which severe toxicity and death occurred after acetamiprid ingestion. A 57-year-old male patient consumed 50g/250mL of an insecticide formulation containing acetamiprid for suicidal purposes. The ambulance team performed cardiopulmonary resuscitation on the patient who had a cardiac arrest. His heart beat returned after a 15-min cardiopulmonary resuscitation, and afterward, he had tachycardia, hypotension, respiratory failure, high gap metabolic acidosis with a high lactate, hypokalemia, hypocalcemia, mydriasis, and coma. The patient underwent supportive treatment for a variety of symptoms. However, he died despite all supportive treatment. This case demonstrates that ingestion of large amounts of the acetamiprid and late presentation can be fatal despite all supportive care.
    MeSH term(s) Fatal Outcome ; Heart Arrest ; Humans ; Insecticides ; Male ; Middle Aged ; Neonicotinoids ; Poisoning/diagnosis ; Respiratory Insufficiency
    Chemical Substances Insecticides ; Neonicotinoids ; acetamiprid (5HL5N372P0)
    Language English
    Publishing date 2022-03-17
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2268721-X
    ISSN 1878-7487 ; 1752-928X
    ISSN (online) 1878-7487
    ISSN 1752-928X
    DOI 10.1016/j.jflm.2022.102335
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Comparison of syncope risk scores in predicting the prognosis of patients presenting to the emergency department with syncope.

    Ince, Cagdas / Gulen, Muge / Acehan, Selen / Sevdimbas, Sarper / Balcik, Muhammet / Yuksek, Ali / Satar, Salim

    Irish journal of medical science

    2023  Volume 192, Issue 6, Page(s) 2727–2734

    Abstract: Background: Various scores have been derived for the assessment of syncope patients in the emergency department (ED).: Aim: We aimed to compare the effectiveness of Canadian Syncope Risk Scores (CSRS), San Francisco Syncope Rules (SFSR), and ... ...

    Abstract Background: Various scores have been derived for the assessment of syncope patients in the emergency department (ED).
    Aim: We aimed to compare the effectiveness of Canadian Syncope Risk Scores (CSRS), San Francisco Syncope Rules (SFSR), and Osservatorio Epidemiologico sulla Sincope nel Lazio (OESIL) risk scores in predicting the risk of major adverse cardiac events (MACE) and mortality among syncope patients within 30 days of the initial ED visit.
    Methods: We performed a prospective, observational case series study of adults (≥ 18 years) with unexplained syncope/near-syncope who presented to ED. Demographic characteristics of the patients and clinical and laboratory data were recorded in the standard data collection form of the study. Our primary outcome was a 30-day mortality.
    Results: A total of 421 patients (mean age 50.9 ± 20.8, 51.5% male) were enrolled. The rate of MACE development in the 30-day follow-up of the patients was 12.8% (n = 54). While 20.2% (n = 85) of the patients were hospitalized, two of the patients died in the emergency room and the 30-day mortality was 5.5% (n = 23). CSRS was found to have the highest predictive power of mortality (AUC: 0.869, 95% CI 0.799-0.939, p < 0.001). If the cut-off value of CSRS was 0.5, the sensitivity was found to be 82.6% and the specificity was 81.9%. Also CSRS (OR: 1.402, 95% CI: 1.053-1.867, p = 0.021) was found to be an independent predictor of the 30-day mortality.
    Conclusion: The CSRS may be used as a safety risk score for a 30-day risk of MACE and mortality after discharge from the emergency department.
    MeSH term(s) Adult ; Female ; Humans ; Male ; Canada ; Emergency Service, Hospital ; Prognosis ; Prospective Studies ; Risk Assessment ; Risk Factors ; Syncope/diagnosis ; Syncope/etiology
    Language English
    Publishing date 2023-05-12
    Publishing country Ireland
    Document type Journal Article ; Observational Study
    ZDB-ID 390895-1
    ISSN 1863-4362 ; 0021-1265
    ISSN (online) 1863-4362
    ISSN 0021-1265
    DOI 10.1007/s11845-023-03395-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Predictors of 30-day mortality in patients diagnosed with hepatic encephalopathy on admission to the emergency department.

    Yuksek, Ali / Acehan, Selen / Satar, Salim / Gulen, Muge / Balcik, Muhammet / Sevdimbas, Sarper / Ince, Cagdas / Koca, Ahmet Naci / Tas, Adnan

    European journal of gastroenterology & hepatology

    2023  Volume 35, Issue 12, Page(s) 1402–1409

    Abstract: Background: The aim of this study is to compare the laboratory findings and disease severity scores of patients diagnosed with hepatic encephalopathy (HE) in the emergency department (ED) to predict 30-day mortality.: Method: The patients over 18 ... ...

    Abstract Background: The aim of this study is to compare the laboratory findings and disease severity scores of patients diagnosed with hepatic encephalopathy (HE) in the emergency department (ED) to predict 30-day mortality.
    Method: The patients over 18 years old and diagnosed HE in the ED of a tertiary hospital were included in the study. Demographic and clinical characteristics, laboratory parameters, predisposing causes and outcomes of the patients included in the study were recorded in the data form. Severity of liver disease was assessed by Child Pugh Score (CPS), End-stage liver disease model (MELD), MELD-Na and MELD-Lactate scores.
    Results: Two hundred fifty-four patients diagnosed with HE were included in the study. 59.1% of the patients were male. The mean age of the patients was 65.2 ± 12.6 years. The mortality rate of the patients was 47.2%. When the receiver operating characteristic (ROC) analysis, which determines the predictive properties of laboratory parameters and disease severity scores, was examined, the area under curve value of the MELD-Lactate score (0.858 95% CI 0.812-0.904, P  < 0.001) was the highest. Binary logistic regression analysis for the estimation of patients' 30-day mortality showed that CPS and MELD-Lactate scores and blood ammonia and B-type natriuretic peptide levels were independent predictors of mortality.
    Conclusion: According to the study data, MELD-Lactate and BNP levels in patients diagnosed with HE in the ED may help the clinician in the prediction of 30-day mortality in the early period.
    MeSH term(s) Humans ; Male ; Middle Aged ; Aged ; Adolescent ; Female ; Hepatic Encephalopathy/diagnosis ; Prognosis ; Retrospective Studies ; End Stage Liver Disease ; ROC Curve ; Lactates ; Emergency Service, Hospital ; Severity of Illness Index
    Chemical Substances Lactates
    Language English
    Publishing date 2023-09-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 1034239-4
    ISSN 1473-5687 ; 0954-691X
    ISSN (online) 1473-5687
    ISSN 0954-691X
    DOI 10.1097/MEG.0000000000002646
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: BUN/albumin ratio predicts short-term mortality better than SYNTAX score in ST-elevation myocardial infarction patients.

    Balcik, Muhammet / Satar, Salim / Gulen, Muge / Acehan, Selen / Sevdimbas, Sarper / Acele, Armagan / Sahin, Gonca Koksaldi / Ince, Cagdas / Aksay, Erdem / Yuksek, Ali

    Journal of cardiovascular medicine (Hagerstown, Md.)

    2023  Volume 24, Issue 6, Page(s) 326–333

    Abstract: Objective: The aim of the study is to compare the prognostic power of the BUN/albumin ratio (BAR) calculated on admission to the emergency department and the SYNergy between Percutaneous Coronary Intervention with TAXus (SYNTAX) score calculated after ... ...

    Abstract Objective: The aim of the study is to compare the prognostic power of the BUN/albumin ratio (BAR) calculated on admission to the emergency department and the SYNergy between Percutaneous Coronary Intervention with TAXus (SYNTAX) score calculated after coronary angiography (CAG) in predicting 30-day mortality in patients with ST-segment elevation myocardial infarction (STEMI).
    Method and material: The study was conducted prospectively between March 2021 and March 2022 in the emergency department of a tertiary hospital. Patients over the age of 18 who underwent CAG with a diagnosis of STEMI were included in the study. Demographic charecteristics, comorbidities, laboratory parameters of the patients at the time of admission and SYNTAX (SX) score were recorded in the data form.
    Results: A total of 1147 patients (77% male) diagnosed with STEMI were included in the study. When the receiver-operating characteristic analysis for SX score and laboratory parameters' power to predict mortality was examined, it was found that the AUC value of the BAR level (AUC: 0.736; 95% confidence interval: 0.670-0.802, P  < 0.001) was the highest. If the threshold value of the serum BAR level, which was determined to predict mortality, was taken as 4, the sensitivity was found to be 76.7% and the specificity was 56.9%. With multivariate logistic analysis, it was determined that the risk of mortality increased by 1.25 for each unit increase in the BAR value in STEMI patients ( P  < 0.001).
    Conclusion: According to the study data, the BAR may guide the clinician in the early period as a practical and valuable predictor of 30-day mortality in patients diagnosed with STEMI.
    MeSH term(s) Humans ; Male ; Adult ; Middle Aged ; Female ; ST Elevation Myocardial Infarction/diagnostic imaging ; ST Elevation Myocardial Infarction/therapy ; Blood Urea Nitrogen ; Prognosis ; Percutaneous Coronary Intervention ; Albumins ; Retrospective Studies ; Coronary Angiography ; Risk Factors
    Chemical Substances Albumins
    Language English
    Publishing date 2023-04-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2223461-5
    ISSN 1558-2035 ; 1558-2027
    ISSN (online) 1558-2035
    ISSN 1558-2027
    DOI 10.2459/JCM.0000000000001473
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Evaluation of Nutrition Risk in Patients Over 65 Years of Age With Nontraumatic Acute Abdominal Syndrome

    Acehan, Selen / Gulen, Muge / Satar, Salim / Kuvvetli, Adnan / Isikber, Cem / Yesiloglu, Onder / Toptas Firat, Basak / Sonmez, Ahmet / Segmen, Mustafa Sencer / Ince, Cagdas

    Nutrition in clinical practice. 2020 Dec., v. 35, no. 6

    2020  

    Abstract: BACKGROUND: The objective of this study is to investigate the power of CRP/Albumin ratio, NRS‐2002, mNUTRIC scores to predict nutritional needs and mortality in patients over 65 years of age diagnosed with acute abdominal syndrome in the emergency ... ...

    Abstract BACKGROUND: The objective of this study is to investigate the power of CRP/Albumin ratio, NRS‐2002, mNUTRIC scores to predict nutritional needs and mortality in patients over 65 years of age diagnosed with acute abdominal syndrome in the emergency department and then transferred to the surgical intensive care unit. MATERIAL AND METHOD: CRP/Albumin ratio, APACHE II, SOFA, NRS‐2002 and mNUTRIC scores were calculated. The analysis of the data was conducted in IBM SPSS Statistics Base 22.0 package program. RESULTS: In the analytical evaluation made for nutritional needs, AUC value for mNUTRIC was found to be: 0,683, 95% CI 0,611‐0,755, p < 0.001. It was found out that mortality of patients had a statistically significant and moderate correlation with mNUTRIC score (r = 0.537; p < 0.001). In the analytical evaluation made for mortality, mNUTRIC's AUC value (AUC: 0.808, 95% CI 0.736‐0.880, p < 0.001) was found to be the highest. When the cut‐off value determined to predict mortality was taken as 3.5 for mNUTRIC score, sensitivity was 75.9% and specificity was 69.4%. CONCLUSION: The evaluation of the risk of malnutrition through nutritional risk tools in intensive care patients over 65 years of age with acute abdominal syndrome can also predict nutritional needs in the early period besides mortality. Based on our data, the fact that mNUTRIC score cut‐off value in older patients hospitalized in intensive care is 3.5 and higher may be a predictor for ICU mortality.
    Keywords albumins ; malnutrition ; mortality ; nutrition risk assessment ; risk
    Language English
    Dates of publication 2020-12
    Size p. 1070-1079.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 645074-x
    ISSN 1941-2452 ; 0884-5336
    ISSN (online) 1941-2452
    ISSN 0884-5336
    DOI 10.1002/ncp.10575
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Evaluation of Nutrition Risk in Patients Over 65 Years of Age With Nontraumatic Acute Abdominal Syndrome.

    Acehan, Selen / Gulen, Muge / Satar, Salim / Kuvvetli, Adnan / Isikber, Cem / Yesiloglu, Onder / Toptas Firat, Basak / Sonmez, Ahmet / Segmen, Mustafa Sencer / Ince, Cagdas

    Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition

    2020  Volume 35, Issue 6, Page(s) 1070–1079

    Abstract: Background: The objective of this study is to investigate the power of CRP/Albumin ratio, NRS-2002, mNUTRIC scores to predict nutritional needs and mortality in patients over 65 years of age diagnosed with acute abdominal syndrome in the emergency ... ...

    Abstract Background: The objective of this study is to investigate the power of CRP/Albumin ratio, NRS-2002, mNUTRIC scores to predict nutritional needs and mortality in patients over 65 years of age diagnosed with acute abdominal syndrome in the emergency department and then transferred to the surgical intensive care unit.
    Material and method: CRP/Albumin ratio, APACHE II, SOFA, NRS-2002 and mNUTRIC scores were calculated. The analysis of the data was conducted in IBM SPSS Statistics Base 22.0 package program.
    Results: In the analytical evaluation made for nutritional needs, AUC value for mNUTRIC was found to be: 0,683, 95% CI 0,611-0,755, p < 0.001. It was found out that mortality of patients had a statistically significant and moderate correlation with mNUTRIC score (r = 0.537; p < 0.001). In the analytical evaluation made for mortality, mNUTRIC's AUC value (AUC: 0.808, 95% CI 0.736-0.880, p < 0.001) was found to be the highest. When the cut-off value determined to predict mortality was taken as 3.5 for mNUTRIC score, sensitivity was 75.9% and specificity was 69.4%.
    Conclusion: The evaluation of the risk of malnutrition through nutritional risk tools in intensive care patients over 65 years of age with acute abdominal syndrome can also predict nutritional needs in the early period besides mortality. Based on our data, the fact that mNUTRIC score cut-off value in older patients hospitalized in intensive care is 3.5 and higher may be a predictor for ICU mortality.
    MeSH term(s) APACHE ; Abdomen, Acute/complications ; Aged ; Humans ; Intensive Care Units ; Malnutrition ; Nutrition Assessment ; Nutritional Status ; Prognosis ; ROC Curve ; Retrospective Studies
    Language English
    Publishing date 2020-09-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645074-x
    ISSN 1941-2452 ; 0884-5336
    ISSN (online) 1941-2452
    ISSN 0884-5336
    DOI 10.1002/ncp.10575
    Database MEDical Literature Analysis and Retrieval System OnLINE

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