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Article ; Online: Increasing emergency department admissions for chemsex-related intoxications in Barcelona, Spain, among people living with HIV: an observational study from 2018 to 2020.

Vallecillo, Gabriel / Losada, Alejandra / Inciarte, Alexy / Jiwei, Chen / Monterde, Albert / Salgado, Emilio / Doi, Adriana Laura / Monclus, Esther / Perelló, Rafael

BMC public health

2022 Volume 22, Issue 1, Page(s) 346

Abstract: Background: Chemsex is a novel phenomenon referring to the use of drugs, including crystal methamphetamine, gammahydroxybutyric acid (GHB)/gamma-butyrolactone (GABA) and mephedrone, to facilitate, enhance, and prolong the sexual experience in men who ... ...

Abstract	Background: Chemsex is a novel phenomenon referring to the use of drugs, including crystal methamphetamine, gammahydroxybutyric acid (GHB)/gamma-butyrolactone (GABA) and mephedrone, to facilitate, enhance, and prolong the sexual experience in men who have sex with men in large cities internationally. There is a growing concern about chemsex and fatal cases among people living with HIV on antiretroviral therapy. This study aimed to describe the clinical characteristics of chemsex-related intoxications. Material and methods: An observational study was conducted in people living with HIV who were admitted for chemsex-related intoxications in an emergency department of a teaching hospital in Barcelona, Spain, from 2018 to 2020. Severe acute intoxications were defined according to the Poisoning Severity Score. Results: One hundred and fifteen male patients with a median age of 35.6±7 years were included in the study:15 (13.1%) in 2018, 32 (27.8%) in 2019 and 68 (59.1%) in 2020. All patients had stable housing, 107(93.0%) were Spanish citizen and 32 (27.8%) had mental health disorders. Median CD4 lymphocyte count was 624 (500-765) cells/mm Conclusions: Chemsex-related intoxications are an increasing clinical problem in people living with HIV. Chemsex should be routinely screened and addressed in clinical practice, particularly for people with mental illness and low CD4 cell counts, who are at higher risk for severe intoxications.
MeSH term(s)	Adult ; Emergency Service, Hospital ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; Homosexuality, Male/psychology ; Humans ; Male ; Methamphetamine ; Sexual Behavior ; Sexual and Gender Minorities ; Spain/epidemiology ; Substance-Related Disorders/epidemiology
Chemical Substances	Methamphetamine (44RAL3456C)
Language	English
Publishing date	2022-02-18
Publishing country	England
Document type	Journal Article ; Observational Study
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-022-12763-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Disparities in Coronavirus Disease 2019 Clinical Outcomes and Vaccination Coverage Among Migrants With Human Immunodeficiency Virus in the PISCIS Cohort: A Population-Based Propensity Score-Matched Analysis.

Nomah, Daniel K / Díaz, Yesika / Bruguera, Andreu / Moreno-Fornés, Sergio / Aceiton, Jordi / Reyes-Urueña, Juliana / Llibre, Josep M / Falcó, Vicenç / Imaz, Arkaitz / Fanjul, Francisco Javier / Peraire, Joaquim / Deig, Elisabet / Domingo, Pere / Inciarte, Alexy / Casabona, Jordi / Miró, José M

Open forum infectious diseases

2024 Volume 11, Issue 1, Page(s) ofad693

Abstract: Background: Coronavirus disease 2019 (COVID-19) disproportionately affects migrants and ethnic minorities, including those with human immunodeficiency virus (HIV). Comprehensive studies are needed to understand the impact and risk factors.: Methods: ... ...

Abstract	Background: Coronavirus disease 2019 (COVID-19) disproportionately affects migrants and ethnic minorities, including those with human immunodeficiency virus (HIV). Comprehensive studies are needed to understand the impact and risk factors. Methods: Using data from the PISCIS cohort of people with HIV (PWH) in Catalonia, Spain, we investigated COVID-19 outcomes and vaccination coverage. Among 10 640 PWH we compared migrants and non-migrants assessing rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing, diagnosis, and associated clinical outcomes through propensity score matching and multivariable Cox regression. Results: The cohort (mean age, 43 years; 83.5% male) included 57.4% (3053) Latin American migrants. Migrants with HIV (MWH) had fewer SARS-CoV-2 tests (67.8% vs 72.1%, Conclusions: MWH had lower rates of SARS-CoV-2 testing and vaccination coverage, although the rates of COVID-19 diagnosis were similar between migrants and non-migrants. Rates of COVID-19-associated hospitalizations and ICU admissions were higher among migrants in comparison with non-migrants, with similar hospitalization duration and mortality. These findings can inform policies to address disparities in future pandemic responses for MWH.
Language	English
Publishing date	2024-01-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2757767-3
ISSN	2328-8957
ISSN	2328-8957
DOI	10.1093/ofid/ofad693
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Article: Toxic-Induced Encephalopathy Following Chemsex in a Young HIV-Positive Male: A Complex Case of Acute Cognitive Impairment with Anterograde Amnesia and Behavioral Alterations.

Inciarte, Alexy / de la Mora, Lorena / Huaier-Arriazu, Emilio / Torres, Berta / Cañizares, Silvia / Zamora, Elizabeth / Laguno, Montserrat / Gonzalez-Cordón, Ana / Foncillas, Alberto / Chivite, Ivan / Calvo, Júlia / Ambrosioni, Juan / Martínez, Esteban / Blanco, Jose Luis / Miro, J M / Martinez-Rebollar, Maria / Mallolas, Josep

Infectious diseases and therapy

2024 Volume 13, Issue 4, Page(s) 647–658

Abstract: Background: A broadened clinical spectrum of concomitant complications emerges among the escalating incidence of substance use, particularly within the 'chemsex' context. This case exemplifies the profound neurotoxic repercussions and neurological risk ... ...

Abstract	Background: A broadened clinical spectrum of concomitant complications emerges among the escalating incidence of substance use, particularly within the 'chemsex' context. This case exemplifies the profound neurotoxic repercussions and neurological risk of chemsex in a young HIV-positive male and addresses the multifaceted challenges of such evolving paradigms in substance utilization. Clinical finding: After consuming cannabis, poppers, methamphetamine, and cocaine, a 28-year-old HIV-positive male exhibited significant neurological and cognitive impairment. The initial presentation included dysarthria and profound anterograde amnesia. Laboratory findings showed leukocytosis with a PCR of 3 mg/dl - elevated cerebrospinal fluid protein levels with no cells. Urine toxicology returned positive for cannabis and amphetamines. A brain CT scan revealed bilateral and symmetrical hippocampi and pale globes hypodensity, indicative of toxic-metabolic encephalopathy. MRI further identified lesions in the globus pallidus, cerebellum, and hippocampi. Following the detection of toxic encephalopathy, Initial neuropsychological was performed screening using the Montreal Cognitive Assessment (MoCA), which highlighted immediate memory deficits. An in-depth neuropsychological assessment conducted 3 weeks later included the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV), the Rey Auditory Verbal Learning Test (RAVLT), and tests for visuospatial skills, motor functions, and memory recall. The evaluations revealed pronounced anterograde amnesia, persistent long-term memory inconsistencies, and notable executive function challenges, detailed in Table 1. Conclusions: The detailed analysis of this case underpins the severe neurological consequences that can manifest from heavy substance use. Comprehensive diagnostic evaluations, including neuroimaging and neuropsychological assessments, are crucial in elucidating the full spectrum of substance-induced cognitive impairments. There is an urgent need for enhanced public awareness and preventative measures, especially in the context of chemsex, to bring forth multifaceted health, social, and government implications that modern society must adeptly navigate.
Language	English
Publishing date	2024-04-03
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2701611-0
ISSN	2193-6382 ; 2193-8229
ISSN (online)	2193-6382
ISSN	2193-8229
DOI	10.1007/s40121-024-00962-x
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Article ; Online: About "Executive summary of the GeSIDA consensus document on control and monitoring of HIV-infected patients".

Modesto Dos Santos, Joao Luis / Laguno, Montserrat / Inciarte, Alexy / González-Cordón, Ana

Enfermedades infecciosas y microbiologia clinica (English ed.)

2020 Volume 38, Issue 6, Page(s) 299–300

MeSH term(s)	Anti-HIV Agents/therapeutic use ; Antiretroviral Therapy, Highly Active ; Consensus ; HIV Infections/drug therapy ; Humans
Chemical Substances	Anti-HIV Agents
Language	Spanish
Publishing date	2020-01-10
Document type	Letter ; Comment
ISSN	2529-993X
ISSN (online)	2529-993X
DOI	10.1016/j.eimc.2019.12.006
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Article: The Combination of an mRNA Immunogen, a TLR7 Agonist and a PD1 Blocking Agent Enhances In-Vitro HIV T-Cell Immune Responses.

Usero, Lorena / Leal, Lorna / Gómez, Carmen Elena / Miralles, Laia / Aurrecoechea, Elena / Esteban, Ignasi / Torres, Berta / Inciarte, Alexy / Perdiguero, Beatriz / Esteban, Mariano / García, Felipe / Plana, Montserrat

Vaccines

2023 Volume 11, Issue 2

Abstract: The development of new strategies to achieve a functional cure for HIV remains a priority. We tested a novel HIV therapeutic vaccine using unmodified mRNA (TMEP-B) and mRNA modified by 1-methyl-3'-pseudouridylyl (TMEP-Bmod) expressing both a ... ...

Abstract	The development of new strategies to achieve a functional cure for HIV remains a priority. We tested a novel HIV therapeutic vaccine using unmodified mRNA (TMEP-B) and mRNA modified by 1-methyl-3'-pseudouridylyl (TMEP-Bmod) expressing both a multiepitopic sequences from Gag, Pol, and Nef proteins, including different CD4 and CD8 T-cell epitopes functionally associated with HIV control in transfected monocyte-derived dendritic cells (MDDCs) obtained from HIV infected patients. In vitro assays were used to test the mRNAs alone and in combination with immunomodulator agents, such as the TLR-7 agonist Vesatolimod and the PD-1 antagonist Nivolumab to try to improve HIV-specific cellular immune responses. Combining the mRNAs with the immunomodulators enhanced HIV-specific T-cell responses, together with the secretion of IFNγ, IP10, MIP-1α, and MIP-1β, which are fundamental mediators of viral control. Our data suggest that the mRNA vaccine prototypes TMEP-B and TMEP-Bmod, when combined with Vesatolimod and/or Nivolumab, could achieve functional cure for patients with HIV.
Language	English
Publishing date	2023-01-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2703319-3
ISSN	2076-393X
ISSN	2076-393X
DOI	10.3390/vaccines11020286
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Article ; Online: Clinical use and effectiveness of dolutegravir and lamivudine: a long-term, real-world, retrospective study.

Martínez-Serra, Adrián / De Lazzari, Elisa / Berrocal, Leire / Foncillas, Alberto / De La Mora, Lorena / Inciarte, Alexy / Chivite, Iván / González-Cordón, Ana / Martínez-Rebollar, María / Torres, Berta / Laguno, Montserrat / Blanco, José Luis / Martínez, Esteban / Mallolas, Josep / Ambrosioni, Juan

The Journal of antimicrobial chemotherapy

2023 Volume 78, Issue 8, Page(s) 1955–1962

Abstract: Background: The use of dolutegravir/lamivudine is based on solid clinical trials; however, real-world data remain limited.: Objectives: To provide data on the clinical use and effectiveness of dolutegravir/lamivudine in persons with HIV in a real- ... ...

Abstract	Background: The use of dolutegravir/lamivudine is based on solid clinical trials; however, real-world data remain limited. Objectives: To provide data on the clinical use and effectiveness of dolutegravir/lamivudine in persons with HIV in a real-world scenario. Patients and methods: Retrospective, single-centre and observational study. We included all adults starting dolutegravir/lamivudine since November 2014. We reported all demographic, virological and immunological variables at baseline and assessed effectiveness [on treatment (OT), modified ITT (mITT) and ITT in those persons who reached 6 and 12 month follow-ups (M6 and M12). Results: Of the 1058 persons, 9 were treatment-naive; the final analysis included 1049 treatment-experienced people with HIV. Median (IQR) follow-up was 1 (0.3-1.6) years, with 81% and 63% persons reaching M6 and M12, respectively. The longest use of dolutegravir/lamivudine was 7.4 years. Per OT, mITT and ITT, HIV-RNA < 50 copies/mL was 97%, 92% and 81% (M6) and 98%, 90% and 80% (M12), respectively. Females [adjusted risk ratio, aRR (95% CI): 1.69 (1.19-2.40)]; immediate, previous PI-based regimen [aRR (95% CI): 1.67 (1.09-2.56)]; and viral load (VL) ≥ 50 copies/mL at dolutegravir/lamivudine initiation [aRR (95% CI): 3.36 (2.32-4.88)] were independently associated with lack of effectiveness at M12; other demographic, immunological and virological variables like previous M184V/I substitutions or virological failure, were unrelated. Of the total, 944 (90%) continued dolutegravir/lamivudine. The most frequent known reason for discontinuation was toxicity [48 (46%) cases]. Conclusions: In our real-world experience, virological suppression rates were high for treatment-experienced persons on dolutegravir/lamivudine; however, we identified subgroups with a higher risk of lack of effectiveness at M12, who may benefit from closer follow-ups.
MeSH term(s)	Adult ; Female ; Humans ; Lamivudine/therapeutic use ; Retrospective Studies ; HIV Infections/drug therapy ; Anti-HIV Agents/therapeutic use ; Drug Therapy, Combination ; Heterocyclic Compounds, 3-Ring/therapeutic use ; Oxazines/therapeutic use ; Pyridones/therapeutic use
Chemical Substances	Lamivudine (2T8Q726O95) ; dolutegravir (DKO1W9H7M1) ; Anti-HIV Agents ; Heterocyclic Compounds, 3-Ring ; Oxazines ; Pyridones
Language	English
Publishing date	2023-06-13
Publishing country	England
Document type	Observational Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	191709-2
ISSN	1460-2091 ; 0305-7453
ISSN (online)	1460-2091
ISSN	0305-7453
DOI	10.1093/jac/dkad189
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Article ; Online: Sex-based epidemiological and immunovirological characteristics of people living with HIV in current follow-up at a tertiary hospital: a comparative retrospective study, Catalonia, Spain, 1982 to 2020.

Toyos, Sara / Berrocal, Leire / González-Cordón, Ana / Inciarte, Alexy / de la Mora, Lorena / Martínez-Rebollar, María / Laguno, Montserrat / Fernández, Emma / Ambrosioni, Juan / Chivite, Iván / de Lazzari, Elisa / Blanco, José Luis / Martínez, Esteban / Miró, José M / Mallolas, Josep / Torres, Berta

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

2023 Volume 28, Issue 10

Abstract: BackgroundEpidemiological and immunovirological features of people living with HIV (PLWH) can vary by sex.AimTo investigate, particularly according to sex, characteristics of PLWH who consulted a tertiary hospital in Barcelona, Spain, in 1982-2020 ... ...

Abstract	BackgroundEpidemiological and immunovirological features of people living with HIV (PLWH) can vary by sex.AimTo investigate, particularly according to sex, characteristics of PLWH who consulted a tertiary hospital in Barcelona, Spain, in 1982-2020.MethodsPLWH, still in active follow-up in 2020 were retrospectively analysed by sex, age at diagnosis, age at data extraction (December 2020), birth place, CD4+ cell counts, and virological failure.ResultsIn total, 5,377 PLWH (comprising 828 women; 15%) were included. HIV diagnoses in women appeared to decrease from the 1990s, representing 7.4% (61/828) of new diagnoses in 2015-2020. From 1997, proportions of new HIV diagnoses from patients born in Latin America seemed to increase; moreover, for women born outside of Spain, the median age at diagnosis appeared to become younger than for those born in Spain, with significant differences observed in 2005-2009 and 2010-2014 (31 vs 39 years (p = 0.001), and 32 vs 42 years (p < 0.001) respectively), but not in 2015-2020 (35 vs 42 years; p = 0.254). Among women, proportions of late diagnoses (CD4+ cells/mm3 < 350) were higher than men (significantly in 2015-2020: 62% (32/52) vs 46% (300/656); p = 0.030). Initially, virological failure rates were higher in women than men, but they were similar in 2015-2020 (12% (6/52) vs 8% (55/659); p = 0.431). Women ≥ 50 years old represented 68% (564/828) of women actively followed up in 2020.ConclusionsWomen still have higher rates of late HIV diagnoses than men. Among currently-followed-up women, ≥ 50 year-olds, who need age-adapted care represent a high percentage. Stratifying PLWH by sex matters for HIV prevention and control interventions.
MeSH term(s)	Male ; Humans ; Female ; Middle Aged ; Spain/epidemiology ; Retrospective Studies ; HIV Infections/diagnosis ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; Tertiary Care Centers ; Follow-Up Studies
Language	English
Publishing date	2023-02-22
Publishing country	Sweden
Document type	Journal Article
ZDB-ID	1338803-4
ISSN	1560-7917 ; 1025-496X
ISSN (online)	1560-7917
ISSN	1025-496X
DOI	10.2807/1560-7917.ES.2023.28.10.2200317
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Zs.A 5066: Show issues

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Article ; Online: Simplification from tenofovir disoproxil fumarate plus lamivudine or emtricitabine plus ritonavir-boosted protease inhibitor to ritonavir-boosted atazanavir plus lamivudine in virologically suppressed HIV-infected adults with osteopenia: a pilot study.

Blanco, José L / Rojas, Jhon / de Lazzari, Elisa / Inciarte, Alexy / Subirana, Mar / Callau, Pilar / Martinez-Rebollar, María / Laguno, Montserrat / Mallolas, Josep / de la Mora, Lorena / Torres, Berta / Gonzalez-Cordón, Ana / Martinez, Esteban

The Journal of antimicrobial chemotherapy

2022 Volume 77, Issue 7, Page(s) 1974–1979

Abstract: Background: Tenofovir disoproxil fumarate, particularly when given with a ritonavir-boosted PI, reduces bone mineral density (BMD) and increases bone turnover markers (BTMs). Ritonavir-boosted atazanavir plus lamivudine is a feasible simplified option. ... ...

Abstract	Background: Tenofovir disoproxil fumarate, particularly when given with a ritonavir-boosted PI, reduces bone mineral density (BMD) and increases bone turnover markers (BTMs). Ritonavir-boosted atazanavir plus lamivudine is a feasible simplified option. We evaluated whether switching from a triple ritonavir-boosted PI plus tenofovir disoproxil fumarate to a two-drug regimen of lamivudine plus ritonavir-boosted atazanavir would improve BMD. Methods: Single-arm pilot study. Virologically suppressed patients on tenofovir disoproxil fumarate plus lamivudine or emtricitabine plus ritonavir-boosted PI with low BMD, without previous resistance mutations and/or virological failure to study drugs were switched to 100/300 mg of ritonavir-boosted atazanavir plus 300 mg of lamivudine once daily. The primary endpoint was BMD change by DXA at Week 48. Results: There were 31 patients, 4 (13%) female, and median age was 40 years. Seven participants (22.5%) had osteoporosis. At 48 weeks, mean (SD) changes in spine and hip BMD were +0.01 (0.03) (P = 0.0239) and +0.013 (0.03) g/cm2 (P = 0.0046), respectively. Mean (SD) T-score changes were +0.1 (0.23) (P = 0.0089) and +0.25 (0.76) (P = 0.0197), respectively. N-telopeptide and urine tenofovir disoproxil fumarate toxicity markers showed significant improvements. One participant withdrew from the study and two were lost to follow-up. There were no virological failures, or serious or grade 3-4 adverse events. Conclusions: Switching from a tenofovir disoproxil fumarate plus ritonavir-boosted PI triple therapy to a lamivudine plus ritonavir-boosted atazanavir two-drug regimen in virologically suppressed HIV-infected adults with low BMD was safe, increased low BMD and reduced plasma markers of bone turnover and urine markers of tenofovir disoproxil fumarate toxicity over 48 weeks.
MeSH term(s)	Adult ; Anti-HIV Agents/therapeutic use ; Atazanavir Sulfate/therapeutic use ; Bone Diseases, Metabolic/chemically induced ; Bone Diseases, Metabolic/prevention & control ; Drug Substitution ; Emtricitabine/therapeutic use ; Female ; HIV Infections/complications ; HIV Infections/drug therapy ; HIV Protease Inhibitors/therapeutic use ; Humans ; Lamivudine/therapeutic use ; Male ; Pilot Projects ; Ritonavir/adverse effects ; Ritonavir/therapeutic use ; Tenofovir/adverse effects ; Tenofovir/therapeutic use
Chemical Substances	Anti-HIV Agents ; HIV Protease Inhibitors ; Lamivudine (2T8Q726O95) ; Atazanavir Sulfate (4MT4VIE29P) ; Tenofovir (99YXE507IL) ; Emtricitabine (G70B4ETF4S) ; Ritonavir (O3J8G9O825)
Language	English
Publishing date	2022-05-05
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	191709-2
ISSN	1460-2091 ; 0305-7453
ISSN (online)	1460-2091
ISSN	0305-7453
DOI	10.1093/jac/dkac137
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Article: Correction to: Impact of Sexualized Substance Use and Other Risk Practices on HCV Microelimination in gbMSM Living with HIV: Urgent Need for Targeted Strategies. Results of a Retrospective Cohort Study.

Martínez-Rebollar, María / De La Mora, Lorena / Campistol, Miriam / Cabrera, Bruno / Bagué, Albert / De Lazzari, Elisa / Torres, Berta / González-Cordón, Ana / Inciarte, Alexy / Ambrosioni, Juan / Martínez, Esteban / Blanco, José L / Forns, Xavier / Blanch, Jordi / Mallolas, Josep / Laguno, Montserrat

Infectious diseases and therapy

2022 Volume 11, Issue 2, Page(s) 933

Language	English
Publishing date	2022-02-16
Publishing country	New Zealand
Document type	Published Erratum
ZDB-ID	2701611-0
ISSN	2193-6382 ; 2193-8229
ISSN (online)	2193-6382
ISSN	2193-8229
DOI	10.1007/s40121-022-00601-3
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Article ; Online: PrEP program experience in a hospital HIV unit. Description of baseline user profile and identification of opportunities for improvement.

Laguno, Montserrat / Ugarte, Ainoa / Martinez-Rebollar, María / Sobrino, Yeray / Font, Guillermo / de Lazzari, Elisa / de la Mora, Lorena / Torres, Berta / Chivite, Iván / Riera, Josep / Ambrosioni, Juan / Inciarte, Alexy / Gonzalez-Cordon, Ana / Rojas, Jhon / Cordon, Encarna / Blanco, José Luis / Martinez, Esteban / Mallolas, Josep

Enfermedades infecciosas y microbiologia clinica (English ed.)

2022 Volume 41, Issue 1, Page(s) 24–28

Abstract: Introduction: Pre-Exposure Prophylaxis (PrEP) is a biomedical intervention to prevent HIV infection in seronegative people at high risk of becoming infected. This strategy was endorsed in October 2019 by the Spanish Ministry of Health.: Objective: To ...

Abstract	Introduction: Pre-Exposure Prophylaxis (PrEP) is a biomedical intervention to prevent HIV infection in seronegative people at high risk of becoming infected. This strategy was endorsed in October 2019 by the Spanish Ministry of Health. Objective: To present the PrEP initial experience in the HIV Unit of the Hospital Clínic of Barcelona, paying special attention to the analysis of the vulnerability factors in the cohort. Materials and methods: Retrospective, descriptive study. The epidemiological, sociodemographic, and clinical characteristics of the users included in the program during the first year are analyzed, paying particular attention to Infections, risky practices, and substance use. Results: 190 individuals were included, 177 men and 12 trans women with a mean age of 35 years (8 SD). 70% had higher education, and half had Spanish nationality. An average of 10 couples per trimester and 60% reported unprotected anal sex. 31% had at least one positive PCR for STIs, with N. gonorrhoeae being the most prevalent microorganism (51%) and the rectal sample the most affected (21%). 63% reported chemsex use, 19% polydrug use, and 8% "slamming". Half expressed concern about consumption and/or sexual practices and 25% the need for help. Conclusions: The PrEP user profile attended in our Hospital Unit justifies the creation of multidisciplinary teams that allow us to provide holistic attention to the sexual life of these people.
MeSH term(s)	Male ; Humans ; Female ; Adult ; HIV Infections/epidemiology ; HIV Infections/prevention & control ; Retrospective Studies ; Homosexuality, Male ; Substance-Related Disorders/epidemiology ; Hospital Units ; Hospitals
Language	English
Publishing date	2022-07-06
Publishing country	Spain
Document type	Journal Article ; Comment
ISSN	2529-993X
ISSN (online)	2529-993X
DOI	10.1016/j.eimce.2022.06.009
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