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  1. Article ; Online: Preventing transmission among operating room staff during COVID-19 pandemic: the role of the Aerosol Box and other personal protective equipment.

    Bianco, F / Incollingo, P / Grossi, U / Gallo, G

    Updates in surgery

    2020  Volume 72, Issue 3, Page(s) 907–910

    Abstract: The COVID-19 pandemic is highly challenging for the operating room staff and healthcare workers in emergency departments. SARS-CoV-2 is a positive-sense single-stranded RNA beta-coronavirus that primarily targets the human respiratory system, with fever, ...

    Abstract The COVID-19 pandemic is highly challenging for the operating room staff and healthcare workers in emergency departments. SARS-CoV-2 is a positive-sense single-stranded RNA beta-coronavirus that primarily targets the human respiratory system, with fever, cough, myalgia, and pneumonia as the most common manifestations. However, since SARS-CoV-2 RNA was detected in stool specimens much more attention has been paid to gastrointestinal symptoms such as loss of appetite, nausea, and diarrhea. Furthermore, the expression of ACE-2 receptors in absorptive enterocytes from ileum and colon suggests that these organs should also be considered as a potential high risk for SARS-CoV-2 infection. During aerosol-generating medical procedures (AGMP; e.g. intubating and extubating patients or any surgical procedures), the production of both airborne particles and droplets may increase the risk of infection. In this situation, the surgical staff is strongly recommended to wear personal protective equipment (PPE). A transparent plastic cube, the so-called "Aerosol Box" (AB), has been recently designed to lend further protection against droplets and aerosol exposure during the AGMP.
    MeSH term(s) Aged ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Humans ; Infection Control/instrumentation ; Infection Control/organization & administration ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Intubation, Intratracheal/instrumentation ; Laparotomy ; Laryngoscopy ; Male ; Middle Aged ; Operating Rooms ; Pandemics/prevention & control ; Personal Protective Equipment ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; Retrospective Studies ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-24
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-020-00818-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Preventing transmission among operating room staff during COVID-19 pandemic: the role of the Aerosol Box and other personal protective equipment

    Bianco, F / Incollingo, P / Grossi, U / Gallo, G

    Updates Surg

    Abstract: The COVID-19 pandemic is highly challenging for the operating room staff and healthcare workers in emergency departments. SARS-CoV-2 is a positive-sense single-stranded RNA beta-coronavirus that primarily targets the human respiratory system, with fever, ...

    Abstract The COVID-19 pandemic is highly challenging for the operating room staff and healthcare workers in emergency departments. SARS-CoV-2 is a positive-sense single-stranded RNA beta-coronavirus that primarily targets the human respiratory system, with fever, cough, myalgia, and pneumonia as the most common manifestations. However, since SARS-CoV-2 RNA was detected in stool specimens much more attention has been paid to gastrointestinal symptoms such as loss of appetite, nausea, and diarrhea. Furthermore, the expression of ACE-2 receptors in absorptive enterocytes from ileum and colon suggests that these organs should also be considered as a potential high risk for SARS-CoV-2 infection. During aerosol-generating medical procedures (AGMP; e.g. intubating and extubating patients or any surgical procedures), the production of both airborne particles and droplets may increase the risk of infection. In this situation, the surgical staff is strongly recommended to wear personal protective equipment (PPE). A transparent plastic cube, the so-called "Aerosol Box" (AB), has been recently designed to lend further protection against droplets and aerosol exposure during the AGMP.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #343406
    Database COVID19

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  3. Article ; Online: Preventing transmission among operating room staff during COVID-19 pandemic

    Bianco, F / Incollingo, P / Grossi, U / Gallo, G

    the role of the Aerosol Box and other personal protective equipment.

    2020  

    Abstract: The COVID-19 pandemic is highly challenging for the operating room staff and healthcare workers in emergency departments. SARS-CoV-2 is a positive-sense single-stranded RNA beta-coronavirus that primarily targets the human respiratory system, with fever, ...

    Abstract The COVID-19 pandemic is highly challenging for the operating room staff and healthcare workers in emergency departments. SARS-CoV-2 is a positive-sense single-stranded RNA beta-coronavirus that primarily targets the human respiratory system, with fever, cough, myalgia, and pneumonia as the most common manifestations. However, since SARS-CoV-2 RNA was detected in stool specimens much more attention has been paid to gastrointestinal symptoms such as loss of appetite, nausea, and diarrhea. Furthermore, the expression of ACE-2 receptors in absorptive enterocytes from ileum and colon suggests that these organs should also be considered as a potential high risk for SARS-CoV-2 infection. During aerosol-generating medical procedures (AGMP; e.g. intubating and extubating patients or any surgical procedures), the production of both airborne particles and droplets may increase the risk of infection. In this situation, the surgical staff is strongly recommended to wear personal protective equipment (PPE). A transparent plastic cube, the so-called "Aerosol Box" (AB), has been recently designed to lend further protection against droplets and aerosol exposure during the AGMP.
    Keywords Aerosol Box ; Aerosol-generating medical procedures ; COVID-19 pandemic ; Operating room ; Personal protective equipment ; Aged ; Betacoronavirus ; Coronavirus Infections ; Humans ; Infection Control ; Infectious Disease Transmission ; Patient-to-Professional ; Intubation ; Intratracheal ; Laparotomy ; Laryngoscopy ; Male ; Middle Aged ; Operating Rooms ; Pandemics ; Pneumonia ; Viral ; Retrospective Studies ; covid19
    Language English
    Publishing country uk
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Preventing transmission among operating room staff during COVID-19 pandemic

    Bianco, F. / Incollingo, P. / Grossi, U. / Gallo, G.

    Updates in Surgery

    the role of the Aerosol Box and other personal protective equipment

    2020  Volume 72, Issue 3, Page(s) 907–910

    Keywords Surgery ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-020-00818-2
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: The short stump and high anastomosis pull-through procedure for delayed coloanal anastomosis with no protective stoma for low rectal cancer - a video vignette.

    Bianco, Francesco / Novi, Alessandra / Incollingo, Paola / Gallo, Gaetano / Grassia, Sebastiano

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2022  Volume 24, Issue 6, Page(s) 801–802

    MeSH term(s) Anal Canal/surgery ; Anastomosis, Surgical/methods ; Colon/surgery ; Digestive System Surgical Procedures ; Humans ; Rectal Neoplasms/surgery ; Surgical Stomas
    Language English
    Publishing date 2022-02-23
    Publishing country England
    Document type Letter ; Video-Audio Media
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Short stump and high anastomosis pull-through (SHiP) procedure for delayed coloanal anastomosis with no protective stoma for low rectal cancer.

    Bianco, Francesco / Incollingo, Paola / Falato, Armando / De Franciscis, Silvia / Belli, Andrea / Carbone, Fabio / Gallo, Gaetano / Fusco, Mario / Romano, Giovanni Maria

    Updates in surgery

    2021  Volume 73, Issue 2, Page(s) 495–502

    Abstract: Despite advances in coloanal anastomosis techniques, satisfactory procedures completed without complications remain lacking. We investigated the effectiveness of our recently developed 'Short stump and High anastomosis Pull-through' (SHiP) procedure for ... ...

    Abstract Despite advances in coloanal anastomosis techniques, satisfactory procedures completed without complications remain lacking. We investigated the effectiveness of our recently developed 'Short stump and High anastomosis Pull-through' (SHiP) procedure for delayed coloanal anastomosis without a stoma. In this retrospective study, we analysed functional outcomes, morbidity, and mortality rates and local recurrence of 37 patients treated using SHiP procedure, out of the 282 patients affected by rectal cancer treated in our institution between 2012 and 2020. The inclusion criterion was that the rectal cancer be located within 4 cm from the anal margin. One patient died of local and pulmonary recurrence after 6 years, one developed lung and liver metastases after 2 years, and one experienced local recurrence 2.5 years after surgery. No major leak, retraction, or ischaemia of the colonic stump occurred; the perioperative mortality rate was zero. Five patients (13.51%) had early complications. Stenosis of the anastomosis, which occurred in nine patients (24.3%), was the only long-term complication; only three (8.1%) were symptomatic and were treated with endoscopic dilation. The mean Wexner scores at 24 and 36 months were 8.3 and 8.1 points, respectively. At the 36-month check-up, six patients (24%) had major LARS, ten (40%) had minor LARS, and nine (36%) had no LARS. The functional results in terms of LARS were similar to those previously reported after immediate coloanal anastomosis with protective stoma. The SHiP procedure resulted in a drastic reduction in major complications, and none of the patients had a stoma.
    MeSH term(s) Anal Canal/surgery ; Anastomosis, Surgical ; Colon/surgery ; Humans ; Neoplasm Recurrence, Local ; Postoperative Complications ; Rectal Neoplasms/surgery ; Retrospective Studies
    Language English
    Publishing date 2021-03-16
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-021-01022-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Comment on "State of the art in magnetic resonance imaging of hepatocellular carcinoma": the role of DWI.

    Granata, Vincenza / Fusco, Roberta / Filice, Salvatore / Incollingo, Paola / Belli, Andrea / Izzo, Francesco / Petrillo, Antonella

    Radiology and oncology

    2019  Volume 53, Issue 3, Page(s) 369–370

    MeSH term(s) Carcinoma, Hepatocellular ; Gadolinium DTPA ; Humans ; Liver Neoplasms ; Magnetic Resonance Imaging
    Chemical Substances Gadolinium DTPA (K2I13DR72L)
    Language English
    Publishing date 2019-07-13
    Publishing country Poland
    Document type Letter ; Comment
    ZDB-ID 1128829-2
    ISSN 1581-3207 ; 0485-893X ; 1318-2099
    ISSN (online) 1581-3207
    ISSN 0485-893X ; 1318-2099
    DOI 10.2478/raon-2019-0031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Our Timing to Remove Peritoneal Catheter Dialysis After Kidney Transplant.

    Peluso, G / Incollingo, P / Carlomagno, N / D'Alessandro, V / Tammaro, V / Caggiano, M / Sandoval Sotelo, M L / Rupealta, N / Candida, M / Mazzoni, G / Campanile, S / Chiacchio, G / Scotti, A / Santangelo, M L

    Transplantation proceedings

    2018  Volume 51, Issue 1, Page(s) 160–163

    Abstract: Background: Patients on peritoneal dialysis treatment represent 15% of the global dialysis population. The major complication of peritoneal dialysis is catheter and peritoneal infection. Peritoneal dialysis patients who receive kidney transplants are at ...

    Abstract Background: Patients on peritoneal dialysis treatment represent 15% of the global dialysis population. The major complication of peritoneal dialysis is catheter and peritoneal infection. Peritoneal dialysis patients who receive kidney transplants are at increased risk of infection because of immunosuppressive therapy.
    Aim: The purpose of this study is to show our ideal timing to remove peritoneal catheter after kidney transplant, which gives adequate security on renal function recovery and reduction of septic risk.
    Method of study: We analyzed the outcomes of 65 patients on peritoneal dialysis who underwent kidney transplant between 2000 and 2016.
    Results: In 61 cases there was an immediate graft functional recovery. In 4 cases there was a delayed graft function (DGF), and we performed a hemodialysis with temporary placement of a venous catheter. In all patients we removed peritoneal dialysis catheter 30 to 45 days after transplant. There has been 1 case of catheter infection, which was treated with antibiotic therapy.
    Discussion: Our average time to remove the peritoneal dialysis catheter was shorter than times in previous studies, between the 30th and 45th postoperative day. In the 4 cases in which there has been a DGF, we performed hemodialysis treatment to avoid, in the immediate postoperative period, direct insults to the peritoneum by local dialysis procedures.
    Conclusion: Our experience show that the 30th to 45th postoperative day is a good time frame, better yet a good watershed between the safe removal of peritoneal catheter when patients have a stabilized renal function and the possibility of leaving it in situ, to resume peritoneal dialysis in case of persistent DGF.
    MeSH term(s) Adult ; Catheters, Indwelling ; Female ; Humans ; Kidney Transplantation ; Male ; Middle Aged ; Peritoneal Dialysis/methods ; Retrospective Studies ; Time Factors
    Language English
    Publishing date 2018-06-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82046-5
    ISSN 1873-2623 ; 0041-1345
    ISSN (online) 1873-2623
    ISSN 0041-1345
    DOI 10.1016/j.transproceed.2018.04.075
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Ethical Issues in the Use of Suboptimal Kidneys for Transplants: An Italian Point of View.

    Incollingo, P / Peluso, G / Pelosio, L / Jamshidi, A A / Montanaro, V / Dodaro, C / Vernillo, A / Minieri, G / Esposito, A / Atontsa, F / Capezzuoli, L / Apostolico, G / Menkulazi, M / Paternoster, M / Calogero, A / Santangelo, M L

    Transplantation proceedings

    2018  Volume 51, Issue 1, Page(s) 106–110

    Abstract: The shortage of organs leads to the need for utilizing suboptimal kidneys for transplantation. The distinction between optimal, marginal, and suboptimal kidneys leads surgeons to face not only technical problems but also ethical and legal issues related ... ...

    Abstract The shortage of organs leads to the need for utilizing suboptimal kidneys for transplantation. The distinction between optimal, marginal, and suboptimal kidneys leads surgeons to face not only technical problems but also ethical and legal issues related to clinical advantages offered by the transplant of a nonstandard kidney and the acquisition of consent. Between 1999 and 2015, we performed 658 transplants, 49 (7.5%) using suboptimal kidneys. All patients were alive and with vital graft throughout follow-up. We did not encounter any major surgical complications. From a technical point of view, our experience and literature review confirm that transplant of suboptimal kidney leads to good clinical results but exposes patients to a increased risks of surgical complications. Therefore, these interventions must take place in hospitals fully prepared for this type of surgery and performed by experienced transplant surgeons with proper matching between organ and recipient. Considering the insufficient resources available, from an ethical and legal point of view, doctors play an essential role in optimizing the use of these kidneys by avoiding wastage of organs, ensuring that transplants are done in suitable patients, and that patients are fully informed and aware of the risks and benefits associated with the specific suboptimal kidney being transplanted. We believe that, in highly specialized centers, the number of suboptimal kidney transplants should be increased, as their use has shown good clinical results and carries fewer ethical issues compared with marginal kidneys. Further, suboptimal kidneys may also be proposed for use in young patients with end-stage renal disease.
    MeSH term(s) Adult ; Graft Survival ; Humans ; Italy ; Kidney/abnormalities ; Kidney Failure, Chronic/surgery ; Kidney Transplantation/ethics ; Kidney Transplantation/methods ; Kidney Transplantation/mortality ; Tissue Donors/legislation & jurisprudence ; Transplants/abnormalities ; Transplants/supply & distribution
    Language English
    Publishing date 2018-06-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82046-5
    ISSN 1873-2623 ; 0041-1345
    ISSN (online) 1873-2623
    ISSN 0041-1345
    DOI 10.1016/j.transproceed.2018.05.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Relation Between Wound Complication and Lymphocele After Kidney Transplantation: A Monocentric Study.

    Peluso, Gaia / Incollingo, Paola / Campanile, Silvia / Menkulazi, Marsela / Scotti, Alessandro / Tammaro, Vincenzo / Calogero, Armando / Dodaro, Concetta / Carlomagno, Nicola / Santangelo, Michele L

    Transplantation proceedings

    2020  Volume 52, Issue 5, Page(s) 1562–1565

    Abstract: Introduction: Wound complication frequently arises after kidney transplantation and its risk factors are well known. In a previous paper we analyzed these factors, and in this new retrospective study we evaluate the influence of lymphocele in the ... ...

    Abstract Introduction: Wound complication frequently arises after kidney transplantation and its risk factors are well known. In a previous paper we analyzed these factors, and in this new retrospective study we evaluate the influence of lymphocele in the development of wound complications.
    Patients and methods: From January 2000 to December 2018, 731 consecutive kidney transplants have been performed in our center. We have analyzed the incidence of wound complication and lymphocele and their risk factors.
    Results: Out of 731 kidney transplants, we have observed wound complications in 115 patients (15.7%) and lymphocele in 158 patients (21.7%). Of these, 70 patients developed both complications (9.5%), but 6 patients have been excluded because they were in therapy with mammalian target of rapamycin inhibitors. Twenty-nine patients (45.3%) presented a first level and 35 patients (54.7%) showed second level wound complications. Lymphocele was the only present factor in just 3 cases (4.6%). The other patients showed diabetes in 28 cases (43.7%), overweight/obesity in 38 (59.3%), delayed graft function in 17 (26.5%), and 60 years or more in 38 (57.8%). The association has been found in 30 out 64 patients treated with tacrolimus (46.8%) and in 34 with cyclosporine (53.1%); 40 patients did not receive muscular layer's reconstruction (62.5%).
    Conclusion: Our experience shows that lymphocele alone is not a predisposing factor for wound dehiscence after kidney transplantation, and they often coexist because they share the same risk factors, the most important being obesity, diabetes and delayed graft function, older age, and surgical techniques. No relation has been observed with calcineurin inhibitor therapy.
    MeSH term(s) Adult ; Aged ; Cyclosporine/therapeutic use ; Delayed Graft Function/complications ; Diabetes Complications/complications ; Female ; Humans ; Immunosuppressive Agents/therapeutic use ; Incidence ; Kidney Transplantation/adverse effects ; Lymphocele/complications ; Male ; Middle Aged ; Obesity/complications ; Retrospective Studies ; Risk Factors ; Sirolimus/therapeutic use ; Surgical Wound Dehiscence/epidemiology ; Tacrolimus/therapeutic use
    Chemical Substances Immunosuppressive Agents ; Cyclosporine (83HN0GTJ6D) ; Sirolimus (W36ZG6FT64) ; Tacrolimus (WM0HAQ4WNM)
    Language English
    Publishing date 2020-04-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82046-5
    ISSN 1873-2623 ; 0041-1345
    ISSN (online) 1873-2623
    ISSN 0041-1345
    DOI 10.1016/j.transproceed.2020.02.053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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