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  1. Book ; Online ; E-Book: Neurology

    Perlman, Jeffrey M. / Inder, Terrie E.

    (Neonatology questions and controversies series)

    2023  

    Abstract: Dr. Richard Polin's Neonatology Questions and Controversies series highlights the toughest challenges facing physicians and care providers in clinical practice, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In ...

    Title variant Neurology :
    Author's details edited by Jeffrey M. Perlman, Terrie Inder
    Series title Neonatology questions and controversies series
    Abstract Dr. Richard Polin's Neonatology Questions and Controversies series highlights the toughest challenges facing physicians and care providers in clinical practice, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today's practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient.
    MeSH term(s) Infant, Newborn, Diseases ; Nervous System Diseases ; Infant, Newborn ; Neonatology/methods ; Neonatology
    Keywords Neonatology ; Newborn infants/Diseases ; Nervous system/Diseases ; Newborn infants
    Subject code 618.928
    Language English
    Dates of publication 2023-2024
    Size 1 online resource (663 pages)
    Edition Fourth edition.
    Publisher Elsevier Inc
    Publishing place Philadelphia, PA
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-323-88078-9 ; 9780323880770 ; 978-0-323-88078-7 ; 0323880770
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Turns out not where but who you're with that really matters.

    Inder, Terrie Eleanor

    Pediatric research

    2020  Volume 88, Issue 4, Page(s) 533–534

    MeSH term(s) Delivery of Health Care, Integrated ; Humans ; Infant, Newborn ; Infant, Premature ; Retrospective Studies ; Sepsis
    Language English
    Publishing date 2020-06-29
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 4411-8
    ISSN 1530-0447 ; 0031-3998
    ISSN (online) 1530-0447
    ISSN 0031-3998
    DOI 10.1038/s41390-020-1040-1
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  3. Article ; Online: Human Milk and Preterm Infant Brain Development: A Narrative Review.

    Belfort, Mandy Brown / Inder, Terrie E

    Clinical therapeutics

    2022  Volume 44, Issue 4, Page(s) 612–621

    Abstract: Purpose: To review and synthesize the literature on human milk and structural brain development and injury in preterm infants, focusing on the application of quantitative brain magnetic resonance imaging (MRI) in this field.: Methods: For this ... ...

    Abstract Purpose: To review and synthesize the literature on human milk and structural brain development and injury in preterm infants, focusing on the application of quantitative brain magnetic resonance imaging (MRI) in this field.
    Methods: For this narrative review, we searched PubMed for articles published from 1990 to 2021 that reported observational or interventional studies of maternal milk or donor milk in relation to brain development and/or injury in preterm infants assessed with quantitative MRI at term equivalent age. Studies were characterized with respect to key aspects of study design, milk exposure definition, and MRI outcomes.
    Findings: We identified 7 relevant studies, all of which were observational in design and published between 2013 and 2021. Included preterm infants were born at or below 33 weeks' gestation. Sample sizes ranged from 22 to 377 infants. Exposure to human milk included both maternal and donor milk. No study included a full-term comparison group. Main MRI outcome domains were white matter integrity (assessed with diffusion tensor imaging, resting state functional connectivity, or semiautomated segmentation of white matter abnormality) and total and regional brain volumes. Studies revealed that greater exposure to human milk versus formula was associated with favorable outcomes, including more mature and connected cerebral white matter with less injury and larger regional brain volumes, notably in the deep nuclear gray matter, amygdala-hippocampus, and cerebellum. No consistent signature effect of human milk exposure was found; instead, the beneficial associations were regional and tissue-specific neuroprotective effects on the areas of known vulnerability in the preterm infant.
    Implications: Evidence to date suggests that human milk may protect the preterm infant from the white matter injury and dysmaturation to which this population is vulnerable. Brain MRI at term equivalent age is emerging as a useful tool to investigate the effects of human milk on the preterm brain. When grounded in neurobiological knowledge about preterm brain injury and development, this approach holds promise for allowing further insight into the mechanisms and pathways underlying beneficial associations of human milk with neurodevelopmental outcomes in this population and in the investigation of specific milk bioactive components with neuroprotective or neurorestorative potential.
    MeSH term(s) Brain/diagnostic imaging ; Diffusion Tensor Imaging ; Humans ; Infant ; Infant, Newborn ; Infant, Premature ; Magnetic Resonance Imaging ; Milk, Human
    Language English
    Publishing date 2022-03-17
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 603113-4
    ISSN 1879-114X ; 0149-2918
    ISSN (online) 1879-114X
    ISSN 0149-2918
    DOI 10.1016/j.clinthera.2022.02.011
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  4. Article ; Online: White Matter Injury on Early-versus-Term-Equivalent Age Brain MRI in Infants Born Preterm.

    Roychaudhuri, Sriya / Côté-Corriveau, Gabriel / Erdei, Carmina / Inder, Terrie E

    AJNR. American journal of neuroradiology

    2024  Volume 45, Issue 2, Page(s) 224–228

    Abstract: Background and purpose: White matter injury in infants born preterm is associated with adverse neurodevelopmental outcomes, depending on the extent and location. White matter injury can be visualized with MR imaging in the initial weeks following ... ...

    Abstract Background and purpose: White matter injury in infants born preterm is associated with adverse neurodevelopmental outcomes, depending on the extent and location. White matter injury can be visualized with MR imaging in the initial weeks following preterm birth but is more commonly defined at term-equivalent-age MR imaging. Our aim was to see how white matter injury detection in MR imaging compares between the 2 time points.
    Materials and methods: This study compared white matter injury on early brain MR imaging (30-34 weeks' postmenstrual age) with white matter injury assessment at term-equivalent (37-42 weeks) MR imaging, using 2 previously published and standardized scoring systems, in a cohort of 30 preterm infants born at <33 weeks' gestational age.
    Results: There was a strong association between the systematic assessments of white matter injury at the 2 time points (
    Conclusions: Although the optimal timing to undertake neuroimaging in the preterm infant remains to be determined, both early (30-34 weeks) and term-equivalent MR imaging provide valuable information on white matter injury and the risk of associated sequelae.
    MeSH term(s) Infant ; Female ; Infant, Newborn ; Humans ; Infant, Premature ; White Matter/diagnostic imaging ; Premature Birth/diagnostic imaging ; Brain/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Brain Injuries/diagnostic imaging ; Neuroimaging ; Gestational Age
    Language English
    Publishing date 2024-02-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603808-6
    ISSN 1936-959X ; 0195-6108
    ISSN (online) 1936-959X
    ISSN 0195-6108
    DOI 10.3174/ajnr.A8105
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  5. Article ; Online: Hypotension: a modifiable risk factor impacting surgical NEC-associated AKI and brain injury in preterm infants.

    Garg, Parvesh Mohan / South, Andrew M / Inder, Terrie / Shenberger, Jeffrey S

    Pediatric research

    2024  

    Language English
    Publishing date 2024-05-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 4411-8
    ISSN 1530-0447 ; 0031-3998
    ISSN (online) 1530-0447
    ISSN 0031-3998
    DOI 10.1038/s41390-024-03244-x
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  6. Article ; Online: Defining the Neurologic Consequences of Preterm Birth. Reply.

    Inder, Terrie E / Volpe, Joseph J / Anderson, Peter J

    The New England journal of medicine

    2023  Volume 389, Issue 19, Page(s) 1827

    MeSH term(s) Female ; Infant, Newborn ; Humans ; Premature Birth/etiology ; Gestational Age ; Neurologic Examination
    Language English
    Publishing date 2023-11-08
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2310222
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  7. Article ; Online: Defining the Neurologic Consequences of Preterm Birth.

    Inder, Terrie E / Volpe, Joseph J / Anderson, Peter J

    The New England journal of medicine

    2023  Volume 389, Issue 5, Page(s) 441–453

    MeSH term(s) Female ; Infant, Newborn ; Humans ; Premature Birth/etiology ; Gestational Age ; Neurologic Examination
    Language English
    Publishing date 2023-07-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMra2303347
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  8. Article ; Online: A unit's experience with hybrid NICU design: description of care model and implications for patients, families, and professionals.

    Erdei, Carmina / Corriveau, Gabriel Cote / Inder, Terrie E

    Journal of perinatology : official journal of the California Perinatal Association

    2023  Volume 43, Issue Suppl 1, Page(s) 35–39

    Abstract: As the first extra-uterine setting for hospitalized infants, the neonatal intensive care unit (NICU) environment can make a lasting impact on their long-term neurodevelopment. This impact is likely mediated through both specific characteristics of the ... ...

    Abstract As the first extra-uterine setting for hospitalized infants, the neonatal intensive care unit (NICU) environment can make a lasting impact on their long-term neurodevelopment. This impact is likely mediated through both specific characteristics of the physical design of the care environment, as well as the experiences that occur within this environment. Recent studies document many established benefits of single-family rooms (SFRs). However, there is concern that infants who spend a prolonged time in SFRs without their parents being intimately involved in their care have reduced opportunities for meaningful experiences, with possible adverse consequences. The purpose of this report is to share an example of an application of the family-centered developmental care model through a hybrid NICU design, inclusive of both SFRs and semi-private bays. In this paper, we empirically describe the physical and operational considerations of a hybrid model, outline the strengths and challenges of this approach, and discuss implications for patients, families, and professionals.
    MeSH term(s) Infant, Newborn ; Humans ; Intensive Care Units, Neonatal ; Parents ; Patients' Rooms ; Patients
    Language English
    Publishing date 2023-12-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645021-0
    ISSN 1476-5543 ; 0743-8346
    ISSN (online) 1476-5543
    ISSN 0743-8346
    DOI 10.1038/s41372-023-01815-0
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  9. Article ; Online: Effect of music-based interventions on physiologic stability of hospitalized preterm infants. A pilot study.

    Erdei, Carmina / Sunwoo, John / Corriveau, Gabriel Cote / Forde, Madison / El-Dib, Mohamed / Inder, Terrie

    Journal of perinatology : official journal of the California Perinatal Association

    2024  Volume 44, Issue 5, Page(s) 665–670

    Abstract: Background and objective: Hospitalized preterm infants experience reduced meaningful auditory exposures during a critical period of brain development. Music-based interventions (MBI) may be beneficial, though it remains unclear which stimuli optimally ... ...

    Abstract Background and objective: Hospitalized preterm infants experience reduced meaningful auditory exposures during a critical period of brain development. Music-based interventions (MBI) may be beneficial, though it remains unclear which stimuli optimally enhance infant stabilization. We investigated the relationship between three conceptually-different MBIs and short-term responses in hospitalized preterm infants.
    Study design: This is a case-crossover pilot study including 21 preterm infants between 30 and 35 weeks postmenstrual age. Participants listened to three MBIs and 'no music'; each condition was provided three times in random order. We monitored physiologic and behavioral parameters around each exposure and analyzed results using linear mixed models.
    Results: Respiratory rates decreased after each MBI compared with 'no music' (p = 0.02). The most notable decrease occurred following exposure to a low, repetitive musical pattern resembling a lullaby (p = 0.01). We noted no significant changes for the remaining parameters.
    Conclusion: Specific MBI characteristics may preferentially enhance physiologic stabilization in hospitalized preterm infants.
    MeSH term(s) Humans ; Pilot Projects ; Infant, Newborn ; Infant, Premature ; Male ; Female ; Cross-Over Studies ; Music Therapy/methods ; Respiratory Rate ; Music
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645021-0
    ISSN 1476-5543 ; 0743-8346
    ISSN (online) 1476-5543
    ISSN 0743-8346
    DOI 10.1038/s41372-024-01907-5
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  10. Article ; Online: Therapeutic hypothermia for preterm infants 34-35 weeks gestational age with neonatal encephalopathy.

    Kim, Seh Hyun / El-Shibiny, Hoda / Inder, Terrie / El-Dib, Mohamed

    Journal of perinatology : official journal of the California Perinatal Association

    2024  Volume 44, Issue 4, Page(s) 528–531

    Abstract: Objective: To evaluate the short-term outcomes and safety of therapeutic hypothermia (TH) for neonatal encephalopathy in preterm infants at 34-35 weeks of gestation.: Study design: A matched retrospective cohort study of 20 preterm infants at 34-35 ... ...

    Abstract Objective: To evaluate the short-term outcomes and safety of therapeutic hypothermia (TH) for neonatal encephalopathy in preterm infants at 34-35 weeks of gestation.
    Study design: A matched retrospective cohort study of 20 preterm infants at 34-35 weeks of gestation and 40 infants at 36 weeks of gestation or more who received TH between the years 2015-2021.
    Result: Short-term outcomes of preterm infants at 34-35 weeks of gestation who received TH were comparable with infants at 36 weeks or more of gestation who received TH regarding seizures, intraventricular hemorrhage, blood transfusions, subcutaneous fat necrosis, brain injury on magnetic resonance imaging, and mortality. These findings were consistent when short-term outcomes were adjusted for birthweight.
    Conclusion: TH in preterm infants at 34-35 weeks of gestation is feasible and safe in our study population.
    MeSH term(s) Infant ; Infant, Newborn ; Humans ; Infant, Premature ; Gestational Age ; Retrospective Studies ; Infant, Newborn, Diseases ; Cerebral Hemorrhage ; Hypothermia, Induced/methods
    Language English
    Publishing date 2024-01-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645021-0
    ISSN 1476-5543 ; 0743-8346
    ISSN (online) 1476-5543
    ISSN 0743-8346
    DOI 10.1038/s41372-024-01874-x
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