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  1. Article ; Online: High- Versus Low-Energy Intertrochanteric Hip Fractures in Young Patients: Injury Characteristics and Factors Associated With Complications.

    Stenquist, Derek S / Albertson, Spencer / Bailey, Daniel / Paladino, Lucas / Flanagan, Christopher D / Stang, Thomas / Watson, David T / Shah, Anjan R / Maxson, Benjamin J / Infante, Anthony F / Donohue, David / Sanders, Roy W / Mir, Hassan R

    Journal of orthopaedic trauma

    2023  Volume 37, Issue 5, Page(s) 222–229

    Abstract: Objective: To compare fracture patterns and associated injuries for young patients with high- versus low-energy intertrochanteric hip fractures and to report on factors associated with complications after surgical fixation of high-energy fractures.: ... ...

    Abstract Objective: To compare fracture patterns and associated injuries for young patients with high- versus low-energy intertrochanteric hip fractures and to report on factors associated with complications after surgical fixation of high-energy fractures.
    Design: Retrospective comparative study.
    Setting: Academic Level 1 Trauma Center.
    Patients: A total of 103 patients 50 years of age or younger were included: 80 high-energy fractures and 23 low-energy fractures.
    Intervention: Cephalomedullary nailing (N = 92) or a sliding hip screw (N = 11).
    Main outcome measures: Radiographic characteristics of fracture morphology, implant position, and reduction quality and postoperative complications were the main outcome measures.
    Results: Compared with young patients with low-energy fractures, those with high-energy fractures had more fracture comminution ( P = 0.013) and higher ISS scores ( P < 0.003) and were more likely to require open reduction ( P < 0.001). Patients with low-energy fractures from a ground-level fall had higher rates of alcohol abuse (0.032), cirrhosis (0.010), and chronic steroid use (0.048). Overall reoperation rate for high-energy fractures was 7%, including 2 IT fracture nonunions (5%) and 1 deep infection (2%). For high-energy fractures, ASA class ( P = 0.026), anterior lag screw position ( P = 0.001), and varus malreduction ( P < 0.001) were associated with malunion. Four-part fracture (OTA/AO 31A2.3/Jensen 5) ( P = 0.028) and residual calcar gap >3 mm ( P = 0.03) were associated with reoperation.
    Conclusions: Surgical treatment of high-energy IT fractures in young patients is technically demanding with potential untoward outcomes. Injury characteristics and severity are significantly different for young patients with high-energy IT fractures compared with low-energy fractures. For young patients with a high-energy IT fracture, surgeons can anticipate a high rate of associated injuries and complex fracture patterns requiring open reduction. For young patients with a low-energy IT fracture, comanagement with a hospitalist or a geriatrician should be considered because they may be physiologically older.
    Level of evidence: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
    MeSH term(s) Humans ; Bone Nails ; Bone Screws/adverse effects ; Fracture Fixation, Intramedullary/adverse effects ; Hip Fractures/diagnostic imaging ; Hip Fractures/epidemiology ; Hip Fractures/surgery ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2023-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639099-7
    ISSN 1531-2291 ; 0890-5339
    ISSN (online) 1531-2291
    ISSN 0890-5339
    DOI 10.1097/BOT.0000000000002587
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Outcomes of Various Antibiotic Cement-Coated Intramedullary Implants on the Treatment of Long Bone Septic Nonunion.

    Lopas, Luke A / Albertson, Spencer / Solomon, Eric / Watson, David T / Shah, Anjan R / Maxson, Benjamin J / Infante, Anthony F / Donohue, David / Downes, Katheryne L / Sanders, Roy W / Mir, Hassan R

    Journal of orthopaedic trauma

    2021  Volume 36, Issue 2, Page(s) 44–50

    Abstract: Objective: To determine the effectiveness of various types of antibiotic-coated intramedullary implants in the treatment of septic long bone nonunion.: Design: Retrospective chart review.: Setting: Level 1 trauma center.: Participants: Forty- ... ...

    Abstract Objective: To determine the effectiveness of various types of antibiotic-coated intramedullary implants in the treatment of septic long bone nonunion.
    Design: Retrospective chart review.
    Setting: Level 1 trauma center.
    Participants: Forty-one patients with septic long bone nonunion treated with an antibiotic cement-coated intramedullary implant.
    Intervention: Surgical debridement and placement of a type of antibiotic-coated intramedullary implant.
    Main outcome measurements: Union and need for reoperation.
    Results: At an average 27-month follow-up (6-104), 27 patients (66%) had a modified radiographic union score of the tibia of 11.5 or greater, 12 patients (29%) a score lower than 11.5, and 2 patients (5%) underwent subsequent amputation. Six patients underwent no further surgical procedures after the index operation. Patients treated with a rigid, locked antibiotic nail achieved earlier weight-bearing (P = 0.001), less frequently required autograft (P = 0.005), and underwent fewer subsequent procedures (average 0.38 vs. 3.60, P = 0.004) than those treated with flexible core antibiotic rods.
    Conclusions: Antibiotic-coated intramedullary implants are successful in the treatment of septic nonunions in long bones. In our cohort, rigid, statically locked nails allowed faster rehabilitation, decreased the need for autograft, and decreased the number of additional surgical procedures. Further study is needed to confirm these findings.
    Level of evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Bone Nails ; Fracture Fixation, Intramedullary ; Fracture Healing ; Humans ; Retrospective Studies ; Tibial Fractures/diagnostic imaging ; Tibial Fractures/drug therapy ; Tibial Fractures/surgery ; Treatment Outcome
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-09-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639099-7
    ISSN 1531-2291 ; 0890-5339
    ISSN (online) 1531-2291
    ISSN 0890-5339
    DOI 10.1097/BOT.0000000000002215
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: "Unstable" Pediatric Femoral Shaft Fractures Treated With Flexible Elastic Nails Have Few Complications.

    Atassi, Omar / Fontenot, Philip B / Busel, Gennadiy / De La Fuente, Guadalupe / Donohue, David / Maxson, Benjamin / Shah, Anjan R / Watson, David T / Infante, Anthony F / Downes, Katheryne / Sanders, Roy W / Mir, Hassan R

    Journal of orthopaedic trauma

    2020  Volume 35, Issue 2, Page(s) e56–e60

    Abstract: Objectives: To determine our complication rate in pediatric femoral shaft fractures treated with flexible elastic nailing and to determine fracture characteristics that may predict complications.: Design: Retrospective cohort study.: Setting: One ... ...

    Abstract Objectives: To determine our complication rate in pediatric femoral shaft fractures treated with flexible elastic nailing and to determine fracture characteristics that may predict complications.
    Design: Retrospective cohort study.
    Setting: One Level 1 and One Level 2 academic trauma centers.
    Patients/participants: One hundred one pediatric femoral shaft fractures treated from 2006 to 2018.
    Main outcome measurement: Major and minor complications.
    Results: One hundred one femurs met inclusion criteria. The average age was 7 years (range 3-12 years). The average weight was 29.0 kg (range 16-55 kg). The average follow-up was 11 months (6-36 months). Ninety-three patients underwent elective implant removal at our institution. Fifty-one of the 101 (50%) fractures were "unstable" patterns. Ninety-three percent had implants that filled >80% of the canal (69 titanium and 32 stainless steel). Seventeen percent (18) had cast immobilization. All fractures went on to union. No patient required revision surgery for malunion as follows: 6 had coronal/sagittal malalignment >10 degrees, 3 had malrotation >15 degrees, and none had a leg length inequality >1 cm. Three patients had an unplanned surgery as follows: 2 for prominent implants and 1 for refracture after a second injury. There were no patient, fracture, or treatment characteristics that were predictive of complications or unplanned surgery, including "unstable" fractures (P = 0.78).
    Conclusion: Our study demonstrates that flexible elastic nailing can be safely used in most pediatric femoral shaft fractures, including those previously described as "unstable."
    Level of evidence: Therapeutic Level IV. See Instructions to Authors for a complete description of levels of evidence.
    MeSH term(s) Bone Nails ; Child ; Child, Preschool ; Femoral Fractures/diagnostic imaging ; Femoral Fractures/surgery ; Fracture Fixation, Intramedullary/adverse effects ; Fracture Healing ; Humans ; Nails ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2020-12-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639099-7
    ISSN 1531-2291 ; 0890-5339
    ISSN (online) 1531-2291
    ISSN 0890-5339
    DOI 10.1097/BOT.0000000000001886
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Cephalomedullary Nail Fixation of Intertrochanteric Femur Fractures: Are Two Proximal Screws Better Than One?

    Serrano, Rafael / Blair, James A / Watson, David T / Infante, Anthony F / Shah, Anjan R / Mir, Hassan R / Maxson, Benjamin J / Downes, Katheryne L / Sanders, Roy W

    Journal of orthopaedic trauma

    2017  Volume 31, Issue 11, Page(s) 577–582

    Abstract: Objectives: To analyze radiographic changes in intertrochanteric (IT) fracture alignment after treatment with either a single sliding lag screw or an integrated compressed and locked, dual screw, cephalomedullary nail construct.: Design: ... ...

    Abstract Objectives: To analyze radiographic changes in intertrochanteric (IT) fracture alignment after treatment with either a single sliding lag screw or an integrated compressed and locked, dual screw, cephalomedullary nail construct.
    Design: Retrospective comparative study.
    Setting: Level 1 regional trauma center.
    Patients: 1004 OTA/AO 31A, 31B2.1 fractures treated with either a single screw cephalomedullary nail (Gamma 3) or an integrated dual screw cephalomedullary nail (InterTAN) between February 1, 2005, and June 30, 2013. Four hundred thirteen remained after exclusion criteria; 130 were treated with a single screw device (79 stable and 51 unstable), and 283 with an integrated dual screw device (155 stable and 128 unstable).
    Intervention: Cephalomedullary nail insertion.
    Outcome measures: Radiographic analysis included fracture pattern, fracture reduction, neck-shaft angle (NSA), and femoral neck shortening (FNS) differences at 3, 6, and 12 months. Measurements were normalized using known lag screw dimensions, digitally corrected for magnification. Rotation between x-rays was controlled using a ratio of known to measured dimensions. The Mann-Whitney U test was used for statistical analysis.
    Results: The single screw device resulted in 2.5 times more varus collapse (NSA) and 2 times more FNS over 1 year, as compared to the locked, integrated dual screw device, regardless of stability (P < 0.001). NSA and FNS changes were greater for both devices in unstable fracture patterns, but significantly less movement occurred with the dual screw device (P < 0.001).
    Conclusions: A cephalomedullary nail with 2 integrated proximal screws that can be compressed and then locked seems to maintain initial IT fracture reduction and subsequent position over time, with less varus collapse and less shortening than a single screw device.
    Level of evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
    MeSH term(s) Aged ; Aged, 80 and over ; Bone Screws ; Cohort Studies ; Confidence Intervals ; Equipment Design ; Female ; Fracture Fixation, Intramedullary/instrumentation ; Fracture Fixation, Intramedullary/methods ; Fracture Healing/physiology ; Hip Fractures/diagnostic imaging ; Hip Fractures/surgery ; Humans ; Internal Fixators ; Middle Aged ; Postoperative Complications/physiopathology ; Postoperative Complications/surgery ; Range of Motion, Articular/physiology ; Recovery of Function ; Retrospective Studies ; Risk Assessment ; Statistics, Nonparametric ; Trauma Centers ; Treatment Outcome ; United States
    Language English
    Publishing date 2017-08-18
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 639099-7
    ISSN 1531-2291 ; 0890-5339
    ISSN (online) 1531-2291
    ISSN 0890-5339
    DOI 10.1097/BOT.0000000000000967
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Open fractures of the calcaneus: soft-tissue injury determines outcome.

    Heier, Keith A / Infante, Anthony F / Walling, Arthur K / Sanders, Roy W

    The Journal of bone and joint surgery. American volume

    2003  Volume 85, Issue 12, Page(s) 2276–2282

    Abstract: Background: Studies of open calcaneal fractures have been limited and have not analyzed results according to wound location, severity of soft-tissue disruption, fracture type, or treatment method. In this study, results were evaluated on the basis of ... ...

    Abstract Background: Studies of open calcaneal fractures have been limited and have not analyzed results according to wound location, severity of soft-tissue disruption, fracture type, or treatment method. In this study, results were evaluated on the basis of the hypothesis that early surgical intervention was indicated.
    Methods: Between 1989 and 1997, 503 calcaneal fractures were treated at our institution, and forty-three of these fractures, in forty-two patients, were open (8.5%). According to the Gustilo classification there were nine type-I, eight type-II, twelve type-IIIA, and thirteen type-IIIB open fractures as well as one type-IIIC open fracture. All fractures were treated according to the same protocol, consisting of intravenous administration of antibiotics chosen on the basis of the wound type, irrigation and débridement in the operating room, temporary wound coverage, and initial stabilization of the limb. Definitive final fixation was performed after the wound was clean, and soft-tissue swelling was minimal. The final follow-up examinations were performed at a minimum of two years after treatment. Clinical results were graded with use of the AOFAS (American Orthopaedic Foot and Ankle Society) score.
    Results: An infection developed at the sites of 37% of the forty-three fractures, with osteomyelitis developing at the sites of 19%. Seven of the nine type-I open fractures were treated with open reduction and internal fixation or with primary fusion, with no major complications and a good-to-excellent short-term result. Three of the eight type-II open fractures were complicated by an infection. Three of the twelve type-IIIA open fractures and ten of the thirteen type-IIIB open fractures were complicated by an infection. Six of the infections associated with a type-IIIB open fracture progressed to osteomyelitis, and three of those cases led to an amputation. Overall, thirteen (50%) of the twenty-six type-III open fractures were complicated by an infection, with osteomyelitis occurring in seven (27%). Thirty-three patients with a total of thirty-four open calcaneal fractures were available for follow-up at a minimum of two years, and an average of fifty-five months. The average AOFAS hindfoot score for the twenty-seven patients who had not undergone amputation was 71 points.
    Conclusions: Open calcaneal fractures have a high propensity for deep infection despite the use of an aggressive treatment protocol to prevent it. It appears that type-I and type-II open fractures associated with a medial wound can be treated with open reduction and internal fixation. Type-II fractures associated with a wound in another location should be treated with limited or no internal fixation. Type-III open fractures, and especially type-IIIB open fractures, require extensive débridement and prompt soft-tissue coverage as soon as possible. Early internal fixation should be avoided in this subgroup because of the high rates of osteomyelitis and subsequent amputation.
    MeSH term(s) Adult ; Age Distribution ; Aged ; Anti-Bacterial Agents/therapeutic use ; Calcaneus/injuries ; Cohort Studies ; Combined Modality Therapy ; Debridement/methods ; Female ; Florida ; Fracture Fixation, Internal/adverse effects ; Fracture Fixation, Internal/methods ; Fracture Healing/physiology ; Fractures, Open/diagnosis ; Fractures, Open/epidemiology ; Fractures, Open/therapy ; Humans ; Incidence ; Injury Severity Score ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Risk Assessment ; Sex Distribution ; Surgical Wound Infection/epidemiology ; Surgical Wound Infection/therapy ; Treatment Outcome ; Wound Healing/physiology
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2003-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 220625-0
    ISSN 1535-1386 ; 0021-9355
    ISSN (online) 1535-1386
    ISSN 0021-9355
    Database MEDical Literature Analysis and Retrieval System OnLINE

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